| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniele Freitas, Caren T D Antoniazzi, Hecson J Segat, Vinícia Garzella Metz, Luciana Taschetto Vey, Raquel C S Barcelos, Thiago Duarte, Marta M M F Duarte, Marilise Escobar Burge. Neonatal tactile stimulation decreases depression-like and anxiety-like behaviors and potentiates sertraline action in young rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 47. issue Pt B. 2016-09-16. PMID:26449401. |
this study was carried out in order to assess the influence of neonatal tactile stimulation (ts) on behavioral and morphological responses related to depression-like and anxiety-like behaviors, assessed following the administration of sertraline (sert), a selective serotonin re-uptake inhibitor (ssri). |
2016-09-16 |
2023-08-13 |
rat |
| Evan J Kyzar, Adam Michael Stewart, Allan V Kaluef. Effects of LSD on grooming behavior in serotonin transporter heterozygous (Sert⁺/⁻) mice. Behavioural brain research. vol 296. 2016-09-15. PMID:26340513. |
the serotonin transporter (sert) is responsible for the reuptake of 5-ht from the synaptic cleft and regulates serotonin signaling in the brain. |
2016-09-15 |
2023-08-13 |
mouse |
| Olivia Taylor, Nick Van Laeken, Filip De Vos, Ingeborgh Polis, Tim Bosmans, Ingeborg Goethals, Rik Achten, Andre Dobbeleir, Eva Vandermeulen, Chris Baeken, Jimmy Saunders, Kathelijne Pereman. In vivo quantification of the [(11)C]DASB binding in the normal canine brain using positron emission tomography. BMC veterinary research. vol 11. 2016-09-02. PMID:26704517. |
[(11)c]-3-amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-benzonitrile ([(11)c]dasb) is currently the mostly used radiotracer for positron emission tomography (pet) quantitative studies of the serotonin transporter (sert) in the human brain but has never been validated in dogs. |
2016-09-02 |
2023-08-13 |
human |
| Robert Schwamborn, Eric Brown, Jana Haas. Elevation of cortical serotonin transporter activity upon peripheral immune challenge is regulated independently of p38 mitogen-activated protein kinase activation and transporter phosphorylation. Journal of neurochemistry. vol 137. issue 3. 2016-08-30. PMID:26924154. |
the serotonin transporter (sert) is responsible for high-affinity serotonin (5-ht) uptake from extracellular fluid and is a prominent pharmacological target in the treatment of depression. |
2016-08-30 |
2023-08-13 |
rat |
| Robert Schwamborn, Eric Brown, Jana Haas. Elevation of cortical serotonin transporter activity upon peripheral immune challenge is regulated independently of p38 mitogen-activated protein kinase activation and transporter phosphorylation. Journal of neurochemistry. vol 137. issue 3. 2016-08-30. PMID:26924154. |
we show here that the activity of the serotonin transporter (sert), a prominent antidepressant target, is up-regulated 24 h following lps administration. |
2016-08-30 |
2023-08-13 |
rat |
| Yuan-Hwa Chou, Wen-Chi Hsieh, Li-Chi Chen, Jiing-Feng Lirng, Shyh-Jen Wan. Association between the serotonin transporter and cytokines: Implications for the pathophysiology of bipolar disorder. Journal of affective disorders. vol 191. 2016-08-22. PMID:26630394. |
reduced brain serotonin transporter (sert) has been demonstrated in bipolar disorder (bd). |
2016-08-22 |
2023-08-13 |
Not clear |
| A A Terentev, A E Lychkova, A N Kazimirsky, A M Puziko. [SEROTONERGIC REGULATION OF IMMUNITY. PART I]. Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology. issue 3. 2016-08-18. PMID:27301140. |
the review describes the influence of serotonin (5-ht) and its receptor, transporter sert and nuclear factor nf-kb on the immune function of the body, particularly in the digestive tract. |
2016-08-18 |
2023-08-13 |
Not clear |
| Yi-Wei Yeh, Pei-Shen Ho, Chun-Yen Chen, Shin-Chang Kuo, Chih-Sung Liang, Che-Hung Yen, Chang-Chih Huang, Chyng-Yann Shiue, Wen-Sheng Huang, Kuo-Hsing Ma, Ru-Band Lu, San-Yuan Huan. Suicidal ideation modulates the reduction in serotonin transporter availability in male military conscripts with major depression: A 4-[18F]-ADAM PET study. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 16. issue 7. 2016-08-17. PMID:26068129. |
the serotonin transporter (sert) has been suggested to be involved in the pathophysiology of depression and suicidal behaviours. |
2016-08-17 |
2023-08-13 |
human |
| Henk Temmingh, Dan J Stei. Anxiety in Patients with Schizophrenia: Epidemiology and Management. CNS drugs. vol 29. issue 10. 2016-08-15. PMID:26482261. |
recent findings implicate the serotonin transporter (sert) genes, brain-derived neurotropic factor (bdnf) genes, and the serotonin 1a (5ht1a) receptor, but are preliminary and in need of replication. |
2016-08-15 |
2023-08-13 |
Not clear |
| Akihiro Mouri, Masashi Ikeda, Takenao Koseki, Nakao Iwata, Toshitaka Nabeshim. The ubiquitination of serotonin transporter in lymphoblasts derived from fluvoxamine-resistant depression patients. Neuroscience letters. vol 617. 2016-08-08. PMID:26845564. |
serotonin transporter (sert) plays a critical role in terminating the function of serotoninergic neurons. |
2016-08-08 |
2023-08-13 |
mouse |
| R Kolanos, F Sakloth, A D Jain, J S Partilla, M H Baumann, R A Glenno. Structural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters. ACS chemical neuroscience. vol 6. issue 10. 2016-08-01. PMID:26217965. |
none of the analogs significantly inhibited [(3)h]serotonin uptake when tested at 10 μm at the serotonin transporter (sert). |
2016-08-01 |
2023-08-13 |
rat |
| Rajeshwari R Solanki, Jamie L Scholl, Michael J Watt, Kenneth J Renner, Gina L Forste. Amphetamine Withdrawal Differentially Increases the Expression of Organic Cation Transporter 3 and Serotonin Transporter in Limbic Brain Regions. Journal of experimental neuroscience. vol 10. 2016-08-01. PMID:27478387. |
extracellular serotonin levels are regulated by the serotonin transporter (sert) and organic cation transporter 3 (oct3), and vhipp oct3 expression is enhanced during 24 hours of amphetamine withdrawal, while sert expression is unaltered. |
2016-08-01 |
2023-08-13 |
rat |
| Maria Raffaella Barbaro, Antonio Di Sabatino, Cesare Cremon, Paolo Giuffrida, Michelangelo Fiorentino, Annalisa Altimari, Lara Bellacosa, Vincenzo Stanghellini, Giovanni Barbar. Interferon-γ is increased in the gut of patients with irritable bowel syndrome and modulates serotonin metabolism. American journal of physiology. Gastrointestinal and liver physiology. vol 310. issue 6. 2016-07-25. PMID:26744473. |
we evaluated the expression and release of interferon (ifn)-γ from the colonic mucosa of patients with ibs and its impact on serotonin reuptake transporter (sert) gene expression in caco-2 cells. |
2016-07-25 |
2023-08-13 |
Not clear |
| Maria Raffaella Barbaro, Antonio Di Sabatino, Cesare Cremon, Paolo Giuffrida, Michelangelo Fiorentino, Annalisa Altimari, Lara Bellacosa, Vincenzo Stanghellini, Giovanni Barbar. Interferon-γ is increased in the gut of patients with irritable bowel syndrome and modulates serotonin metabolism. American journal of physiology. Gastrointestinal and liver physiology. vol 310. issue 6. 2016-07-25. PMID:26744473. |
these results suggest that ifn-γ downregulates sert expression, hence likely playing a role in altered serotonin metabolism of patients with ibs. |
2016-07-25 |
2023-08-13 |
Not clear |
| N L Baganz, K M Lindler, C B Zhu, J T Smith, M J Robson, H Iwamoto, E S Deneris, W A Hewlett, R D Blakel. A requirement of serotonergic p38α mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors. Translational psychiatry. vol 5. 2016-07-19. PMID:26529424. |
the antidepressant-sensitive 5-ht transporter (sert, slc6a4), a critical determinant of synaptic 5-ht inactivation, can be regulated by pro-inflammatory cytokine signaling. |
2016-07-19 |
2023-08-13 |
mouse |
| N L Baganz, K M Lindler, C B Zhu, J T Smith, M J Robson, H Iwamoto, E S Deneris, W A Hewlett, R D Blakel. A requirement of serotonergic p38α mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors. Translational psychiatry. vol 5. 2016-07-19. PMID:26529424. |
systemic innate immune system activation via intraperitoneal lipopolysaccharide (lps) injection rapidly elevates brain sert activity and 5-ht clearance. |
2016-07-19 |
2023-08-13 |
mouse |
| N L Baganz, K M Lindler, C B Zhu, J T Smith, M J Robson, H Iwamoto, E S Deneris, W A Hewlett, R D Blakel. A requirement of serotonergic p38α mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors. Translational psychiatry. vol 5. 2016-07-19. PMID:26529424. |
to establish a role of serotonergic p38α mapk signaling in lps/il-1β-induced sert regulation and attendant behavioral responses, we pursued studies in mice that afford conditional elimination of p38α mapk in 5-ht neurons (p38α(5ht-)). |
2016-07-19 |
2023-08-13 |
mouse |
| N L Baganz, K M Lindler, C B Zhu, J T Smith, M J Robson, H Iwamoto, E S Deneris, W A Hewlett, R D Blakel. A requirement of serotonergic p38α mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors. Translational psychiatry. vol 5. 2016-07-19. PMID:26529424. |
we found p38α(5ht-) and control (p38α(5ht+)) littermates to be indistinguishable in viability and growth and to express equivalent levels of sert protein and synaptosomal 5-ht transport activity. |
2016-07-19 |
2023-08-13 |
mouse |
| N L Baganz, K M Lindler, C B Zhu, J T Smith, M J Robson, H Iwamoto, E S Deneris, W A Hewlett, R D Blakel. A requirement of serotonergic p38α mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors. Translational psychiatry. vol 5. 2016-07-19. PMID:26529424. |
our studies support an obligate role of p38α mapk signaling in 5-ht neurons for the translation of immune activation to sert regulation and 5-ht-modulated behaviors. |
2016-07-19 |
2023-08-13 |
mouse |
| Aaron Janowsky, Dilip K Tosh, Amy J Eshleman, Kenneth A Jacobso. Rigid Adenine Nucleoside Derivatives as Novel Modulators of the Human Sodium Symporters for Dopamine and Norepinephrine. The Journal of pharmacology and experimental therapeutics. vol 357. issue 1. 2016-07-19. PMID:26813929. |
several compounds inhibited or enhanced binding at the norepinephrine transporter (net) and serotonin transporter (sert) and inhibited function in the micromolar range; truncation at the 4'-position in compound 23 allowed for weak inhibition of the sert. |
2016-07-19 |
2023-08-13 |
human |