| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irene Lopez-Vilchez, Maribel Diaz-Ricart, Ana M Galan, Merce Roque, Carolina Caballo, Patricia Molina, James G White, Gines Escola. Internalization of Tissue Factor-Rich Microvesicles by Platelets Occurs Independently of GPIIb-IIIa, and Involves CD36 Receptor, Serotonin Transporter and Cytoskeletal Assembly. Journal of cellular biochemistry. vol 117. issue 2. 2016-10-31. PMID:26221761. |
inhibitory strategies to block glycoprotein iib-iiia (gpiib-iiia), scavenger receptor cd36, serotonin transporter (sert) and pi3k, fully prevented platelet aggregation by tf+mvs. |
2016-10-31 |
2023-08-13 |
human |
| Melissa M Conti, Adam A A Goldenberg, Alexandra Kuberka, Mohamed Mohamed, Satie Eissa, David Lindenbach, Christopher Bisho. Effect of tricyclic antidepressants on L-DOPA-induced dyskinesia and motor improvement in hemi-parkinsonian rats. Pharmacology, biochemistry, and behavior. vol 142. 2016-10-31. PMID:26791104. |
therefore, in order to examine the differential roles of monoamine transporters in l-dopa's behavioral effects, three tricyclic antidepressants (tca) with graded affinity for serotonin (sert) vs. norepinephrine (net) transporters were tested in hemi-parkinsonian rats: clomipramine (sert>net), amitriptyline (sert=net), and desipramine (sert
| 2016-10-31 |
2023-08-13 |
rat |
|
| Jui-Hu Shih, Kuo-Hsing Ma, Chien-Fu F Chen, Cheng-Yi Cheng, Li-Heng Pao, Shao-Ju Weng, Yuahn-Sieh Huang, Chyng-Yann Shiue, Ming-Kung Yeh, I-Hsun L. Evaluation of brain SERT occupancy by resveratrol against MDMA-induced neurobiological and behavioral changes in rats: A 4-[¹⁸F]-ADAM/small-animal PET study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 1. 2016-10-27. PMID:26612383. |
mdma abusers are often accompanied by long-term serotonergic neurotoxicity, which is associated with reduced density of cerebral serotonin transporters (sert) and depressive disorders. |
2016-10-27 |
2023-08-13 |
rat |
| Mikko Joensuu, Pasi Ahola, Paul Knekt, Olavi Lindfors, Pirjo Saarinen, Tommi Tolmunen, Minna Valkonen-Korhonen, Ritva Vanninen, Tuija Jääskeläinen, Esa Virtala, Jyrki Kuikka, Jari Tiihonen, Johannes Lehtone. Baseline symptom severity predicts serotonin transporter change during psychotherapy in patients with major depression. Psychiatry and clinical neurosciences. vol 70. issue 1. 2016-10-24. PMID:26311446. |
the role of the serotonin transporter (sert) in the pathophysiology of depression is unclear and only a few follow-up studies exist. |
2016-10-24 |
2023-08-13 |
Not clear |
| Rong Zhu, Doris Sinwel, Peter S Hasenhuetl, Kusumika Saha, Vivek Kumar, Peng Zhang, Christian Rankl, Marion Holy, Sonja Sucic, Oliver Kudlacek, Andreas Karner, Walter Sandtner, Thomas Stockner, Hermann J Gruber, Michael Freissmuth, Amy Hauck Newman, Harald H Sitte, Peter Hinterdorfe. Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites. Angewandte Chemie (International ed. in English). vol 55. issue 5. 2016-10-21. PMID:26695726. |
here, we have designed novel tools for atomic force microscopy that directly measure the interaction forces between the serotonin transporter (sert) and the s- and r-enantiomers of citalopram on the single molecule level. |
2016-10-21 |
2023-08-13 |
Not clear |
| Marion France, Emmalee Skorich, Mark Kadrofske, Greg M Swain, James J Galliga. Sex-related differences in small intestinal transit and serotonin dynamics in high-fat-diet-induced obesity in mice. Experimental physiology. vol 101. issue 1. 2016-10-19. PMID:26381722. |
levels of extracellular 5-ht depend on enterochromaffin (ec) cell release and serotonin transporter (sert) uptake. |
2016-10-19 |
2023-08-13 |
mouse |
| Marion France, Emmalee Skorich, Mark Kadrofske, Greg M Swain, James J Galliga. Sex-related differences in small intestinal transit and serotonin dynamics in high-fat-diet-induced obesity in mice. Experimental physiology. vol 101. issue 1. 2016-10-19. PMID:26381722. |
greater sert protein, decreased extracellular 5-ht and greater mucosal 5-hydroxyindolacetic acid were observed in female hfd-fed compared with cd-fed mice. |
2016-10-19 |
2023-08-13 |
mouse |
| Karen E Murray, Kerry J Ressler, Michael J Owen. In vivo investigation of escitalopram's allosteric site on the serotonin transporter. Pharmacology, biochemistry, and behavior. vol 141. 2016-10-19. PMID:26621784. |
clinical evidence and mapping of the serotonin transporter (sert) identified that escitalopram, in addition to its binding to a primary uptake-blocking site, is capable of binding to the sert via an allosteric site that is hypothesized to alter escitalopram's kinetics at the sert. |
2016-10-19 |
2023-08-13 |
mouse |
| Jonathan Nzakizwanayo, Cinzia Dedi, Guy Standen, Wendy M Macfarlane, Bhavik A Patel, Brian V Jone. Escherichia coli Nissle 1917 enhances bioavailability of serotonin in gut tissues through modulation of synthesis and clearance. Scientific reports. vol 5. 2016-10-13. PMID:26616662. |
the former pointed to modulation of tryptophan hydroxylase-1 to enhance 5-ht synthesis, while the latter indicates an impact on clearance into enterocytes through sert. |
2016-10-13 |
2023-08-13 |
mouse |
| K Berghauzen-Maciejewska, J Wardas, B Kosmowska, H Domin, M Śmiałowska, U Głowacka, K Ossowsk. Adaptive down-regulation of the serotonin transporter in the 6-hydroxydopamine-induced rat model of preclinical stages of Parkinson's disease and after chronic pramipexole treatment. Neuroscience. vol 314. 2016-10-13. PMID:26628402. |
the aim of the present study was to examine the influence of the above lesion and chronic pra treatment on binding to the serotonin transporter (sert) in different brain regions. |
2016-10-13 |
2023-08-13 |
rat |
| Olivér Éliás, Katalin Nógrádi, György Domány, Zoltán Szakács, János Kóti, Csaba Szántay, Ákos Tarcsay, György M Keserű, Anikó Gere, Béla Kiss, Dalma Kurkó, Sándor Kolok, Zsolt Némethy, Zoltán Kapui, Éva Hellinger, Mónika Vastag, Katalin Sághy, Rita Kedves, István Gyertyá. The influence of 5-HT(2A) activity on a 5-HT(2C) specific in vivo assay used for early identification of multiple acting SERT and 5-HT(2C) receptor ligands. Bioorganic & medicinal chemistry letters. vol 26. issue 3. 2016-10-13. PMID:26748694. |
the influence of 5-ht(2a) activity on a 5-ht(2c) specific in vivo assay used for early identification of multiple acting sert and 5-ht(2c) receptor ligands. |
2016-10-13 |
2023-08-13 |
mouse |
| Olivér Éliás, Katalin Nógrádi, György Domány, Zoltán Szakács, János Kóti, Csaba Szántay, Ákos Tarcsay, György M Keserű, Anikó Gere, Béla Kiss, Dalma Kurkó, Sándor Kolok, Zsolt Némethy, Zoltán Kapui, Éva Hellinger, Mónika Vastag, Katalin Sághy, Rita Kedves, István Gyertyá. The influence of 5-HT(2A) activity on a 5-HT(2C) specific in vivo assay used for early identification of multiple acting SERT and 5-HT(2C) receptor ligands. Bioorganic & medicinal chemistry letters. vol 26. issue 3. 2016-10-13. PMID:26748694. |
as a result of our exploratory programme aimed at elaborating dually acting compounds towards the serotonin (5-ht) transporter (sert) and the 5-ht2c receptor a novel series of 3-amino-1-phenylpropoxy substituted diphenylureas was identified. |
2016-10-13 |
2023-08-13 |
mouse |
| Samantha E Yohn, Laura Lopez-Cruz, Peter H Hutson, Merce Correa, John D Salamon. Effects of lisdexamfetamine and s-citalopram, alone and in combination, on effort-related choice behavior in the rat. Psychopharmacology. vol 233. issue 6. 2016-10-12. PMID:26694811. |
motivational symptoms are resistant to some treatments, including serotonin transport (sert) inhibitors. |
2016-10-12 |
2023-08-13 |
rat |
| Ajinkya Sase, Yogesh D Aher, Sivaprakasam R Saroja, Minu Karthika Ganesan, Sunetra Sase, Marion Holy, Harald Höger, Vasiliy Bakulev, Gerhard F Ecker, Thierry Langer, Harald H Sitte, Johann Leban, Gert Lube. A heterocyclic compound CE-103 inhibits dopamine reuptake and modulates dopamine transporter and dopamine D1-D3 containing receptor complexes. Neuropharmacology. vol 102. 2016-10-07. PMID:26407764. |
binding of ce-103 to the dopamine (dat), serotonin (sert) and norepinephrine (net) transporters and dopamine reuptake inhibition was tested as well as blood brain permeation and a screen for gpcr targets. |
2016-10-07 |
2023-08-13 |
rat |
| Anu Aonurm-Helm, Kaili Anier, Tamara Zharkovsky, Eero Castrén, Tomi Rantamäki, Vladimir Stepanov, Jaak Järv, Alexander Zharkovsk. NCAM-deficient mice show prominent abnormalities in serotonergic and BDNF systems in brain - Restoration by chronic amitriptyline. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 12. 2016-10-05. PMID:26499173. |
serotonergic nerve fiber density and sert (serotonin transporter) protein levels were robustly reduced in the hippocampus, prefrontal cortex and basolateral amygdala of adult ncam(-)(/-) mice. |
2016-10-05 |
2023-08-13 |
mouse |
| Zhong-Min Wu, Chun-Hua Zheng, Zhen-Hua Zhu, Feng-Tian Wu, Gui-Lian Ni, Yong Lian. SiRNA-mediated serotonin transporter knockdown in the dorsal raphe nucleus rescues single prolonged stress-induced hippocampal autophagy in rats. Journal of the neurological sciences. vol 360. 2016-10-05. PMID:26723990. |
one of the hypotheses is the dysfunction of serotonin (5-ht) neurotransmission, which is critically regulated by serotonin transporter (sert). |
2016-10-05 |
2023-08-13 |
rat |
| Johan Hygum Dam, Dirk Bender, Dan Peters, Kjell Någre. [¹¹C]NS9531, [¹¹C]NS9762 and [¹¹C]NS6417, specific SERT tracers: pre-clinical evaluation in pigs and optimization of synthesis conditions using [¹¹C]methyl triflate. Nuclear medicine and biology. vol 43. issue 1. 2016-09-26. PMID:26702786. |
ns9531, ns9762 and ns6417 are nitroquinolinyl-diazabicyclo-alkane derivatives that have been developed as inhibitors of serotonin reuptake transporters (sert) by neurosearch a/s. |
2016-09-26 |
2023-08-13 |
Not clear |
| Julie A Marusich, Kateland R Antonazzo, Bruce E Blough, Simon D Brandt, Pierce V Kavanagh, John S Partilla, Michael H Bauman. The new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue. Neuropharmacology. vol 101. 2016-09-22. PMID:26362361. |
here, the monoamine-releasing properties of 5-it, its structural isomer 6-(2-aminopropyl)indole (6-it), and mdma were compared using in vitro release assays at transporters for dopamine (dat), norepinephrine (net), and serotonin (sert) in rat brain synaptosomes. |
2016-09-22 |
2023-08-13 |
mouse |
| Jong-Hoon Kim, Young-Don Son, Jeong-Hee Kim, Eun-Jung Choi, Sang-Yoon Lee, Yo-Han Joo, Young-Bo Kim, Zang-Hee Ch. Self-transcendence trait and its relationship with in vivo serotonin transporter availability in brainstem raphe nuclei: An ultra-high resolution PET-MRI study. Brain research. vol 1629. 2016-09-22. PMID:26459992. |
we examined the relationship between self-transcendence and serotonin transporter (sert) availability in brainstem raphe nuclei, which are collections of five different serotonergic nuclei with rostro-caudal extension, using ultra-high resolution magnetic resonance imaging (mri) and positron emission tomography (pet) with (11)c-3-amino-4-(2-dimethylaminomethylphenylthio)benzonitrile ([(11)c]dasb) to elucidate potential roles of serotonergic neuronal activities in this personality trait. |
2016-09-22 |
2023-08-13 |
human |
| Friederike Matthaeus, Patrick Schloss, Thorsten La. Differential Uptake Mechanisms of Fluorescent Substrates into Stem-Cell-Derived Serotonergic Neurons. ACS chemical neuroscience. vol 6. issue 12. 2016-09-21. PMID:26503837. |
the actions of the neurotransmitters serotonin, dopamine, and norepinephrine are partly terminated by diffusion and in part by their uptake into neurons via the selective, high-affinity transporters for serotonin (sert), dopamine (dat), and norepinephrine (net), respectively. |
2016-09-21 |
2023-08-13 |
Not clear |