| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rebecca L Brindley, Mary Beth Bauer, Randy D Blakely, Kevin P M Curri. An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus-secretion coupling in sympathoadrenal chromaffin cells. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:27544824. |
5-ht reduced the number of amperometric spikes (vesicular fusion events) evoked by kcl in sert(-/-) cells and wild-type cells treated with escitalopram, a sert antagonist. |
2018-02-22 |
2023-08-13 |
mouse |
| Rebecca L Brindley, Mary Beth Bauer, Randy D Blakely, Kevin P M Curri. An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus-secretion coupling in sympathoadrenal chromaffin cells. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:27544824. |
spike charge and kinetics were not altered by 5-ht receptors but were reduced in sert(-/-) cells compared to wild-type cells. |
2018-02-22 |
2023-08-13 |
mouse |
| Thomas Vanicek, Alexandra Kutzelnigg, Cecile Philippe, Helen L Sigurdardottir, Gregory M James, Andreas Hahn, Georg S Kranz, Anna Höflich, Alexander Kautzky, Tatjana Traub-Weidinger, Marcus Hacker, Wolfgang Wadsak, Markus Mitterhauser, Siegfried Kasper, Rupert Lanzenberge. Altered interregional molecular associations of the serotonin transporter in attention deficit/hyperactivity disorder assessed with PET. Human brain mapping. vol 38. issue 2. 2018-02-12. PMID:27770470. |
the main objectives of this positron emission tomography (pet) study were to investigate the serotonin transporter binding potential (sert bp |
2018-02-12 |
2023-08-13 |
Not clear |
| Danielle Krout, Meghan Rodriquez, Stephen A Brose, Mikhail Y Golovko, L Keith Henry, Brent J Thompso. Inhibition of the Serotonin Transporter Is Altered by Metabolites of Selective Serotonin and Norepinephrine Reuptake Inhibitors and Represents a Caution to Acute or Chronic Treatment Paradigms. ACS chemical neuroscience. vol 8. issue 5. 2018-02-07. PMID:27959497. |
previous studies of transgenic mice carrying a single isoleucine to methionine substitution (i172m) in the serotonin transporter (sert) demonstrated a loss of sensitivity to multiple antidepressants (ads) at sert. |
2018-02-07 |
2023-08-13 |
mouse |
| Alex G Nackenoff, Linda D Simmler, Nicole L Baganz, Alan L Pehrson, Connie Sánchez, Randy D Blakel. Serotonin Transporter-Independent Actions of the Antidepressant Vortioxetine As Revealed Using the SERT Met172 Mouse. ACS chemical neuroscience. vol 8. issue 5. 2018-02-07. PMID:28272863. |
serotonin transporter-independent actions of the antidepressant vortioxetine as revealed using the sert met172 mouse. |
2018-02-07 |
2023-08-13 |
mouse |
| Alex G Nackenoff, Linda D Simmler, Nicole L Baganz, Alan L Pehrson, Connie Sánchez, Randy D Blakel. Serotonin Transporter-Independent Actions of the Antidepressant Vortioxetine As Revealed Using the SERT Met172 Mouse. ACS chemical neuroscience. vol 8. issue 5. 2018-02-07. PMID:28272863. |
selective serotonin (5-ht, sert) reuptake inhibitors (ssris) are the most commonly prescribed treatments for depression. |
2018-02-07 |
2023-08-13 |
mouse |
| Alex G Nackenoff, Linda D Simmler, Nicole L Baganz, Alan L Pehrson, Connie Sánchez, Randy D Blakel. Serotonin Transporter-Independent Actions of the Antidepressant Vortioxetine As Revealed Using the SERT Met172 Mouse. ACS chemical neuroscience. vol 8. issue 5. 2018-02-07. PMID:28272863. |
at therapeutic doses, vortioxetine interacts with sert as well as 5-ht |
2018-02-07 |
2023-08-13 |
mouse |
| Jana Haase, Joanna Grudzinska-Goebel, Heidi Kaastrup Müller, Agnieszka Münster-Wandowski, Elysian Chow, Kieran Wynne, Zohreh Farsi, Johannes-Friedrich Zander, Gudrun Ahnert-Hilge. Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis. ACS chemical neuroscience. vol 8. issue 5. 2018-02-07. PMID:28362488. |
the serotonin transporter (sert) mediates na |
2018-02-07 |
2023-08-13 |
Not clear |
| Rebecca L Brindley, Mary Beth Bauer, Randy D Blakely, Kevin P M Curri. Serotonin and Serotonin Transporters in the Adrenal Medulla: A Potential Hub for Modulation of the Sympathetic Stress Response. ACS chemical neuroscience. vol 8. issue 5. 2018-02-07. PMID:28406285. |
the 5-ht transporter (sert; slc6a4) is a key regulator of 5-ht signaling, and genetic variations in sert are associated with various disorders including depression, anxiety, and autism. |
2018-02-07 |
2023-08-13 |
mouse |
| Franziska Zientek, Karsten Winter, Astrid Müller, Michael Rullmann, Julia Luthardt, Georg-Alexander Becker, Anke Bresch, Marianne Patt, Osama Sabri, Anja Hilbert, Swen Hess. Effortful control as a dimension of temperament is negatively associated with prefrontal serotonin transporter availability in obese and non-obese individuals. The European journal of neuroscience. vol 44. issue 7. 2018-02-01. PMID:27519298. |
we aimed to investigate a possible association between serotonin transmission and regulative temperament in obese and non-obese individuals by using positron emission tomography (pet) imaging of serotonin transporters (sert) and the adult temperament questionnaire. |
2018-02-01 |
2023-08-13 |
Not clear |
| Walid Tajeddinn, Torbjörn Persson, Javier Calvo-Garrido, Mohammed Seed Ahmed, Silvia Maioli, Swetha Vijayaraghavan, Mehmet Selim Kazokoglu, Cristina Parrado-Fernández, Takashi Yoshitake, Jan Kehr, Paul Francis, Bengt Winblad, Kina Höglund, Angel Cedazo-Minguez, Dag Aarslan. Pharmacological Modulations of the Serotonergic System in a Cell-Model of Familial Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 53. issue 1. 2018-01-29. PMID:27163814. |
the 5-ht homeostasis is regulated by many factors, including serotonin transporter (sert), monoamine oxidase enzyme (mao), and several 5-ht receptors, including the 5-ht1b. |
2018-01-29 |
2023-08-13 |
Not clear |
| Walid Tajeddinn, Torbjörn Persson, Javier Calvo-Garrido, Mohammed Seed Ahmed, Silvia Maioli, Swetha Vijayaraghavan, Mehmet Selim Kazokoglu, Cristina Parrado-Fernández, Takashi Yoshitake, Jan Kehr, Paul Francis, Bengt Winblad, Kina Höglund, Angel Cedazo-Minguez, Dag Aarslan. Pharmacological Modulations of the Serotonergic System in a Cell-Model of Familial Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 53. issue 1. 2018-01-29. PMID:27163814. |
sh-sy5y neuroblastoma cells transfected with the amyloid precursor protein (app) gene containing the swedish mutations causing familial ad (appswe), were used as a model to explore the effect of aβ pathology on 5-ht1b and related molecules including the receptor adaptor protein (p11), sert and maoa gene expression, and maoa activity after treatment with selective serotonin reuptake inhibitor (ssri) (sertraline), and a 5-ht1b receptor antagonist. |
2018-01-29 |
2023-08-13 |
Not clear |
| Robin M Hallett, Adele Girgis-Gabardo, William D Gwynne, Andrew O Giacomelli, Jennifer N P Bisson, Jeremy E Jensen, Anna Dvorkin-Gheva, John A Hassel. Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer. Oncotarget. vol 7. issue 33. 2018-01-18. PMID:27447971. |
we found that inhibitors of the serotonin reuptake transporter (sert) and serotonin receptors, which include approved drugs used to treat mood disorders, were potent inhibitors of mouse btic activity as determined by functional sphere-forming assays and the initiation of tumor formation by transplant of drug-exposed tumor cells into syngeneic mice. |
2018-01-18 |
2023-08-13 |
mouse |
| A Komorowski, G M James, C Philippe, G Gryglewski, A Bauer, M Hienert, M Spies, A Kautzky, T Vanicek, A Hahn, T Traub-Weidinger, D Winkler, W Wadsak, M Mitterhauser, M Hacker, S Kasper, R Lanzenberge. Association of Protein Distribution and Gene Expression Revealed by PET and Post-Mortem Quantification in the Serotonergic System of the Human Brain. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 1. 2018-01-15. PMID:27909009. |
pet binding values and gene expression intensities were correlated for the main inhibitory (5-ht1a) and excitatory (5-ht2a) serotonin receptor, the serotonin transporter (sert) as well as monoamine oxidase-a (mao-a), using spearman's correlation coefficients (rs) in a voxel-wise and region-wise analysis. |
2018-01-15 |
2023-08-13 |
human |
| Xiaoning Chen, Emilie I Petit, Kostantin Dobrenis, Ji Ying Sz. Spatiotemporal SERT expression in cortical map development. Neurochemistry international. vol 98. 2018-01-08. PMID:27282696. |
here, we characterize temporal- and spatial-defined expression of serotonin (5-ht) transporter (sert) in glutamatergic neurons during sensory map development in mice. |
2018-01-08 |
2023-08-13 |
mouse |
| Xiaoning Chen, Emilie I Petit, Kostantin Dobrenis, Ji Ying Sz. Spatiotemporal SERT expression in cortical map development. Neurochemistry international. vol 98. 2018-01-08. PMID:27282696. |
we previously identified that knockout of sert in the thalamic neurons blocks 5-ht uptake by their thalamocortical axons, resulting in excessive 5-ht signaling that impairs sensory map architecture. |
2018-01-08 |
2023-08-13 |
mouse |
| Lauren M Federici, Sarah Dorsey Roth, Connie Krier, Stephanie D Fitz, Todd Skaar, Anantha Shekhar, Janet S Carpenter, Philip L Johnso. Anxiogenic CO2 stimulus elicits exacerbated hot flash-like responses in a rat menopause model and hot flashes in postmenopausal women. Menopause (New York, N.Y.). vol 23. issue 11. 2018-01-08. PMID:27465717. |
we also assessed tst responses in ovex serotonin transporter (sert) rats that models a common polymorphism that is associated with increased climacteric symptoms in postmenopausal women and increases in anxiety traits. |
2018-01-08 |
2023-08-13 |
rat |
| Christopher L Muller, Allison Mj Anacker, Tiffany D Rogers, Nick Goeden, Elizabeth H Keller, C Gunnar Forsberg, Travis M Kerr, Carly LA Wender, George M Anderson, Gregg D Stanwood, Randy D Blakely, Alexandre Bonnin, Jeremy Veenstra-VanderWeel. Impact of Maternal Serotonin Transporter Genotype on Placental Serotonin, Fetal Forebrain Serotonin, and Neurodevelopment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 2. 2018-01-05. PMID:27550733. |
biomarker, neuroimaging, and genetic findings implicate the serotonin transporter (sert) in autism spectrum disorder (asd). |
2018-01-05 |
2023-08-13 |
mouse |
| Christopher L Muller, Allison Mj Anacker, Tiffany D Rogers, Nick Goeden, Elizabeth H Keller, C Gunnar Forsberg, Travis M Kerr, Carly LA Wender, George M Anderson, Gregg D Stanwood, Randy D Blakely, Alexandre Bonnin, Jeremy Veenstra-VanderWeel. Impact of Maternal Serotonin Transporter Genotype on Placental Serotonin, Fetal Forebrain Serotonin, and Neurodevelopment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 2. 2018-01-05. PMID:27550733. |
previously, we found that adult male mice expressing the autism-associated sert ala56 variant have altered central serotonin (5-ht) system function, as well as elevated peripheral blood 5-ht levels. |
2018-01-05 |
2023-08-13 |
mouse |
| Christopher L Muller, Allison Mj Anacker, Tiffany D Rogers, Nick Goeden, Elizabeth H Keller, C Gunnar Forsberg, Travis M Kerr, Carly LA Wender, George M Anderson, Gregg D Stanwood, Randy D Blakely, Alexandre Bonnin, Jeremy Veenstra-VanderWeel. Impact of Maternal Serotonin Transporter Genotype on Placental Serotonin, Fetal Forebrain Serotonin, and Neurodevelopment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 2. 2018-01-05. PMID:27550733. |
we therefore used different combinations of maternal and embryo sert ala56 genotypes to examine effects on blood, placenta and embryo serotonin levels and neurodevelopment at embryonic day e14.5, when peripheral sources of 5-ht predominate, and e18.5, when midbrain 5-ht projections have reached the forebrain. |
2018-01-05 |
2023-08-13 |
mouse |