| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andreas Gammelgaard Damsbo, Kristian Lundsgaard Kraglund, Henriette Nørmølle Buttenschøn, Søren Paaske Johnsen, Grethe Andersen, Janne Kaergaard Mortense. Serotonergic Regulation and Cognition after Stroke: The Role of Antidepressant Treatment and Genetic Variation. Cerebrovascular diseases (Basel, Switzerland). vol 47. issue 1-2. 2020-02-04. PMID:30844812. |
sert gene expression may be important for cognition and selective serotonin reuptake inhibitors (ssri) may improve cognition post stroke. |
2020-02-04 |
2023-08-13 |
Not clear |
| Anna Rickli, Marius C Hoener, Matthias E Liecht. Pharmacological profiles of compounds in preworkout supplements ("boosters"). European journal of pharmacology. vol 859. 2020-01-28. PMID:31265842. |
we investigated whether substances that are contained in commercially available athletic multiple-ingredient preworkout supplements exert amphetamine-type activity at norepinephrine, dopamine, and serotonin transporters (net, dat, and sert, respectively). |
2020-01-28 |
2023-08-13 |
human |
| John J Tackett, Neeru Gandotra, Michaela C Bamdad, Eleanor D Muise, Robert A Cowle. Potentiation of serotonin signaling protects against intestinal ischemia and reperfusion injury in mice. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 31. issue 3. 2020-01-22. PMID:30394002. |
knock-out of serotonin re-uptake transporters (sert) or use of selective serotonin re-uptake inhibitors (ssris) potentiates enteric serotonin (5-ht) signaling and stimulates enterocyte proliferation. |
2020-01-22 |
2023-08-13 |
mouse |
| Roberto Laureano-Melo, Janaina Sena de Souza, Rodrigo Rodrigues da Conceição, Josie Marcelle Lira Albuquerque, Nayana Coutinho Rodrigues, Bruno Guimarães Marinho, Emerson Lopes Olivares, Gisele Giannocco, Wellington da Silva Côrte. Prenatal thyroxine treatment promotes anxiolysis in male Swiss mice offspring. Hormones and behavior. vol 108. 2020-01-22. PMID:30576638. |
in the hippocampus, t4 offspring had a higher expression of tryptophan hydroxylase 2 (tph2), serotonin transporter (sert) and glutamate decarboxylase 67 (gad 67) in comparison to controls. |
2020-01-22 |
2023-08-13 |
mouse |
| Vesna Lazarevic, Ioannis Mantas, Ivana Flais, Per Svenningsso. Fluoxetine Suppresses Glutamate- and GABA-Mediated Neurotransmission by Altering SNARE Complex. International journal of molecular sciences. vol 20. issue 17. 2020-01-21. PMID:31480244. |
their primary mechanism of action is considered to be the increased synaptic concentration of serotonin through blockade of the serotonin transporter (sert). |
2020-01-21 |
2023-08-13 |
Not clear |
| Merijn Joling, Chris Vriend, Pieter G H M Raijmakers, Jessica J van der Zande, Afina W Lemstra, Henk W Berendse, Jan Booij, Odile A van den Heuve. Striatal DAT and extrastriatal SERT binding in early-stage Parkinson's disease and dementia with Lewy bodies, compared with healthy controls: An NeuroImage. Clinical. vol 22. 2020-01-17. PMID:30884365. |
we aimed to study degeneration of terminals with dopamine and serotonin transporter (dat and sert, respectively) in patients with early-stage pd and dlb relative to healthy controls, using |
2020-01-17 |
2023-08-13 |
Not clear |
| Brian A Baldo, Michael A Ros. The anaesthetist, opioid analgesic drugs, and serotonin toxicity: a mechanistic and clinical review. British journal of anaesthesia. vol 124. issue 1. 2020-01-06. PMID:31653394. |
the serotonin transporter (sert) maintains low serotonin concentrations and is important for the reuptake of the neurotransmitter into the presynaptic nerve terminals. |
2020-01-06 |
2023-08-13 |
Not clear |
| Brian A Baldo, Michael A Ros. The anaesthetist, opioid analgesic drugs, and serotonin toxicity: a mechanistic and clinical review. British journal of anaesthesia. vol 124. issue 1. 2020-01-06. PMID:31653394. |
some opioids inhibit the reuptake of serotonin by inhibiting sert, thus increasing the plasma and synaptic cleft serotonin concentrations that activate the serotonin receptors. |
2020-01-06 |
2023-08-13 |
Not clear |
| Brian A Baldo, Michael A Ros. The anaesthetist, opioid analgesic drugs, and serotonin toxicity: a mechanistic and clinical review. British journal of anaesthesia. vol 124. issue 1. 2020-01-06. PMID:31653394. |
opioids that are good inhibitors of sert (tramadol, dextromethorphan, methadone, and meperidine) are most frequently associated with serotonin toxicity. |
2020-01-06 |
2023-08-13 |
Not clear |
| Felix P Mayer, Daniela Cintulova, Dorothea A Pittrich, Laurin Wimmer, Dino Luethi, Marion Holy, Kathrin Jaentsch, Sonja Tischberger, Guenter Gmeiner, Marius C Hoener, Matthias E Liechti, Marko D Mihovilovic, Harald H Sitt. Stereochemistry of phase-1 metabolites of mephedrone determines their effectiveness as releasers at the serotonin transporter. Neuropharmacology. vol 148. 2019-12-27. PMID:30610839. |
mephedrone (4-methyl-n-methylcathinone) is a psychostimulant that promotes release of monoamines via the high affinity transporters for dopamine (dat), norepinephrine (net) and serotonin (sert). |
2019-12-27 |
2023-08-13 |
human |
| Felix P Mayer, Diethart Schmid, Marion Holy, Lynette C Daws, Harald H Sitt. "Polytox" synthetic cathinone abuse: A potential role for organic cation transporter 3 in combined cathinone-induced efflux. Neurochemistry international. vol 123. 2019-12-26. PMID:30248432. |
mdpv and mephedrone interfere with the function of the high affinity transporters for dopamine (dat), norepinephrine (net) and serotonin (sert), resulting in increased extracellular levels of these monoamines, though their mechanism of action differs. |
2019-12-26 |
2023-08-13 |
Not clear |
| Danielle M Bailey, Mackenzie A Catron, Oleg Kovtun, Robert L Macdonald, Qi Zhang, Sandra J Rosentha. Single Quantum Dot Tracking Reveals Serotonin Transporter Diffusion Dynamics are Correlated with Cholesterol-Sensitive Threonine 276 Phosphorylation Status in Primary Midbrain Neurons. ACS chemical neuroscience. vol 9. issue 11. 2019-12-23. PMID:29787674. |
serotonin transporter (sert) terminates serotonin signaling in the brain by enabling rapid clearance of the neurotransmitter. |
2019-12-23 |
2023-08-13 |
rat |
| Adele Stewart, Gwynne L Davis, Paul J Gresch, Rania M Katamish, Rodeania Peart, Maximilian J Rabil, Raajaram Gowrishankar, F Ivy Carroll, Maureen K Hahn, Randy D Blakel. Serotonin transporter inhibition and 5-HT Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 5. 2019-12-18. PMID:30578419. |
given that amphetamine and methylphenidate, unlike cocaine, lack high-affinity interactions with the serotonin (5-ht) transporter (sert), we hypothesized that the lack of cocaine-induced hyperlocomotion in dat val559 mice arises from sert blockade and augmented 5-ht signaling relative to cocaine actions on wildtype animals. |
2019-12-18 |
2023-08-13 |
mouse |
| Adele Stewart, Gwynne L Davis, Paul J Gresch, Rania M Katamish, Rodeania Peart, Maximilian J Rabil, Raajaram Gowrishankar, F Ivy Carroll, Maureen K Hahn, Randy D Blakel. Serotonin transporter inhibition and 5-HT Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 5. 2019-12-18. PMID:30578419. |
furthermore, genetic elimination of high-affinity cocaine interactions at sert in dat val559 mice, or specific inhibition of 5-ht |
2019-12-18 |
2023-08-13 |
mouse |
| Aya Matsui, Veronica A Alvare. Cocaine Inhibition of Synaptic Transmission in the Ventral Pallidum Is Pathway-Specific and Mediated by Serotonin. Cell reports. vol 23. issue 13. 2019-12-10. PMID:29949769. |
the inhibition is independent of dopamine receptor activation, absent in 5-ht1b knockout mice, and mimicked by a serotonin transporter (sert) blocker. |
2019-12-10 |
2023-08-13 |
mouse |
| Denis A Nikishin, Nina M Alyoshina, Maria L Semenova, Yuri B Shmukle. Analysis of Expression and Functional Activity of Aromatic L-Amino Acid Decarboxylase (DDC) and Serotonin Transporter (SERT) as Potential Sources of Serotonin in Mouse Ovary. International journal of molecular sciences. vol 20. issue 12. 2019-11-29. PMID:31234589. |
analysis of expression and functional activity of aromatic l-amino acid decarboxylase (ddc) and serotonin transporter (sert) as potential sources of serotonin in mouse ovary. |
2019-11-29 |
2023-08-13 |
mouse |
| Denis A Nikishin, Nina M Alyoshina, Maria L Semenova, Yuri B Shmukle. Analysis of Expression and Functional Activity of Aromatic L-Amino Acid Decarboxylase (DDC) and Serotonin Transporter (SERT) as Potential Sources of Serotonin in Mouse Ovary. International journal of molecular sciences. vol 20. issue 12. 2019-11-29. PMID:31234589. |
we performed a study of the expression and functional activity of the serotonin transporter (sert) and the enzyme for the synthesis of serotonin, aromatic l-amino acid decarboxylase (ddc) in mouse ovary. |
2019-11-29 |
2023-08-13 |
mouse |
| Denis A Nikishin, Nina M Alyoshina, Maria L Semenova, Yuri B Shmukle. Analysis of Expression and Functional Activity of Aromatic L-Amino Acid Decarboxylase (DDC) and Serotonin Transporter (SERT) as Potential Sources of Serotonin in Mouse Ovary. International journal of molecular sciences. vol 20. issue 12. 2019-11-29. PMID:31234589. |
a pronounced peak of sert mrna expression occurs at the age of 14 days, but serotonin synthesis enzymes are expressed at the maximum level in the ovaries of newborn mice. |
2019-11-29 |
2023-08-13 |
mouse |
| Denis A Nikishin, Nina M Alyoshina, Maria L Semenova, Yuri B Shmukle. Analysis of Expression and Functional Activity of Aromatic L-Amino Acid Decarboxylase (DDC) and Serotonin Transporter (SERT) as Potential Sources of Serotonin in Mouse Ovary. International journal of molecular sciences. vol 20. issue 12. 2019-11-29. PMID:31234589. |
these data indicate that the main mechanism of serotonin accumulation in mouse ovary is its uptake by the specific sert membrane transporter, which is active in the oocytes of the growing ovarian follicles. |
2019-11-29 |
2023-08-13 |
mouse |
| Paola Brivio, Judith R Homberg, Marco A Riva, Francesca Calabres. Alterations of Glutamatergic Markers in the Prefrontal Cortex of Serotonin Transporter Knockout Rats: A Developmental Timeline. Cellular and molecular neurobiology. vol 39. issue 5. 2019-11-22. PMID:30915622. |
we previously demonstrated that juvenile serotonin transporter knockout (sert |
2019-11-22 |
2023-08-13 |
rat |