| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Molly H B Amador, M Danielle McDonal. Molecular and functional characterization of the Gulf toadfish serotonin transporter SLC6A4. The Journal of experimental biology. vol 221. issue Pt 7. 2019-07-17. PMID:29487159. |
the serotonin transporter (sert) functions in the uptake of the neurotransmitter serotonin (5-ht) from the extracellular milieu and is the molecular target of the selective serotonin re-uptake inhibitors (ssris), a common group of anti-depressants. |
2019-07-17 |
2023-08-13 |
zebrafish |
| Ying-Peng Chen, Shu-Song Ying, Hong-Hong Zheng, Yan-Ting Liu, Zhong-Ping Wang, Hu Zhang, Xu Deng, Yi-Jing Wu, Xiu-Mei Gao, Tian-Xiang Li, Yan Zhu, Yan-Tong Xu, Hong-Hua W. Novel serotonin transporter regulators: Natural aristolane- and nardosinane- types of sesquiterpenoids from Nardostachys chinensis Batal. Scientific reports. vol 7. issue 1. 2019-07-08. PMID:29118341. |
serotonin transporter (sert) is a classic target of drug discovery for neuropsychiatric and digestive disorders, and against those disorders, plants of nardostachys genus have been valued for centuries in the systems of traditional chinese medicine, ayurvedic and unani. |
2019-07-08 |
2023-08-13 |
Not clear |
| Zhenjiang Xia, Yan Xu, Jichun Han, Qiangqiang He, Jinjin Dong, Xiaoyan Zou, Yuzhi DU, Jing Shang, Lixin We. [Metabolic analysis of serotonin system in serum and gastric tissues of ovalbumin-induced allergic mice]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 34. issue 4. 2019-07-08. PMID:29973322. |
the mrna levels of tryptophan hydroxylase-1 (tph1), indolamine-2, 3-dioxygenase 1 (ido1), monoamine oxidase a (mao-a), 5-hydroxytryptamine 1a receptor (htr1a), 5-hydroxytryptamine 3 receptor (htr3), 5-hydroxytryptamine 4 receptor (htr4) and serotonin reuptake transporter (sert) were determined by real-time quantitative pcr. |
2019-07-08 |
2023-08-13 |
mouse |
| Murugan Mukilan, David Mary Rajathei, Edwin Jeyaraj, Nagarajan Kayalvizhi, Koilmani Emmanuvel Raja. MiR-132 regulated olfactory bulb proteins linked to olfactory learning in greater short-nosed fruit bat Cynopterus sphinx. Gene. vol 671. 2019-07-05. PMID:29859284. |
in addition, western blot analysis depicts that hprt, serotonin transporter (sert), n-methyl-d-asparate (nmda) receptors (2a,b) were down-regulated, but not altered in ob of non-sense oligodeoxynucleotide (ns-odn) infused groups. |
2019-07-05 |
2023-08-13 |
Not clear |
| Eun-Jae Lee, Mi-Sun Oh, Jong S Kim, Dae-Il Chang, Jong-Ho Park, Jae-Kwan Cha, Ji Hoe Heo, Sung-Il Sohn, Dong-Eog Kim, Hahn Young Kim, Jei Kim, Woo-Keun Seo, Jun Lee, Sang-Won Park, Yun Joong Kim, Byung-Chul Le. Serotonin transporter gene polymorphisms may be associated with poststroke neurological recovery after escitalopram use. Journal of neurology, neurosurgery, and psychiatry. vol 89. issue 3. 2019-07-03. PMID:29030421. |
we aimed to investigate whether serotonin transporter (sert) gene polymorphisms are related to the responsiveness to ssris in the poststroke neurological recovery. |
2019-07-03 |
2023-08-13 |
Not clear |
| Stefano Gabriele, Marco Canali, Carla Lintas, Roberto Sacco, Maria Cristina Tirindelli, Arianna Ricciardello, Antonio M Persic. Evidence that ITGB3 promoter variants increase serotonin blood levels by regulating platelet serotonin transporter trafficking. Human molecular genetics. vol 28. issue 7. 2019-07-01. PMID:30535103. |
hyperserotonemia is mainly due to greater 5-ht uptake into platelets, mediated by the 5-ht transporter (sert) located at the platelet plasma membrane. |
2019-07-01 |
2023-08-13 |
Not clear |
| Stefano Gabriele, Marco Canali, Carla Lintas, Roberto Sacco, Maria Cristina Tirindelli, Arianna Ricciardello, Antonio M Persic. Evidence that ITGB3 promoter variants increase serotonin blood levels by regulating platelet serotonin transporter trafficking. Human molecular genetics. vol 28. issue 7. 2019-07-01. PMID:30535103. |
this same allele is strongly associated with (a) higher 5-ht blood levels in 176 autistic individuals (p < 0.001), (b) greater platelet integrin β3 protein expression (p < 0.05) and (c) enhanced sert trafficking from the cytosol toward the platelet plasma membrane (p = 4.05 × 10-11). |
2019-07-01 |
2023-08-13 |
Not clear |
| Mamangam Subaraja, Arambakkam Janardhanam Vanisre. Aberrant neurotransmissional mRNAs in cerebral ganglions of rotenone-exposed Lumbricus terrestris exhibiting motor dysfunction and altered cognitive behavior. Environmental science and pollution research international. vol 26. issue 14. 2019-06-19. PMID:30868461. |
gaba, cholinergic receptor, serotonin transporter (sert), acetylcholine esterase (ache), and dopamine-β-hydroxylase that are well known for their involvement in neuromuscular junctions were investigated by qrt-pcr. |
2019-06-19 |
2023-08-13 |
Not clear |
| Linda D Simmler, Matthias E Liecht. Pharmacology of MDMA- and Amphetamine-Like New Psychoactive Substances. Handbook of experimental pharmacology. vol 252. 2019-06-13. PMID:29633178. |
these mdma-like substances primarily act by inhibiting the serotonin (5-ht) transporter (sert) and net, also inducing 5-ht and ne release. |
2019-06-13 |
2023-08-13 |
Not clear |
| Philip L Johnson, Andrei I Molosh, Lauren M Federici, Cristian Bernabe, David Haggerty, Stephanie D Fitz, Eugene Nalivaiko, William Truitt, Anantha Shekha. Assessment of fear and anxiety associated behaviors, physiology and neural circuits in rats with reduced serotonin transporter (SERT) levels. Translational psychiatry. vol 9. issue 1. 2019-06-12. PMID:30670681. |
assessment of fear and anxiety associated behaviors, physiology and neural circuits in rats with reduced serotonin transporter (sert) levels. |
2019-06-12 |
2023-08-13 |
rat |
| Philip L Johnson, Andrei I Molosh, Lauren M Federici, Cristian Bernabe, David Haggerty, Stephanie D Fitz, Eugene Nalivaiko, William Truitt, Anantha Shekha. Assessment of fear and anxiety associated behaviors, physiology and neural circuits in rats with reduced serotonin transporter (SERT) levels. Translational psychiatry. vol 9. issue 1. 2019-06-12. PMID:30670681. |
genetic variation in serotonin transporter (sert) that reduces transcriptional efficiency is associated with higher anxiety and fear traits and a greater incidence of post traumatic stress disorder (ptsd). |
2019-06-12 |
2023-08-13 |
rat |
| Neil C Lax, Stacy-Ann J Parker, Edward J Hilton, Youstina Seliman, Kevin J Tidgewell, Benedict J Kolbe. Cyanobacterial extract with serotonin receptor subtype 7 (5-HT Synapse (New York, N.Y.). vol 72. issue 11. 2019-06-10. PMID:29992647. |
out of 276 fractions screened, 21% had activity at 5-htrs and/or the 5-ht transporter (sert). |
2019-06-10 |
2023-08-13 |
Not clear |
| Sonali N Reisinger, Thomas Wanek, Oliver Langer, Daniela D Polla. PET imaging of the mouse brain reveals a dynamic regulation of SERT density in a chronic stress model. Translational psychiatry. vol 9. issue 1. 2019-06-10. PMID:30745564. |
the serotonin transporter (sert, slc6a4) plays an important role in the regulation of serotonergic neurotransmission and its aberrant expression has been linked to several psychiatric conditions. |
2019-06-10 |
2023-08-13 |
mouse |
| Brenda Mc Mahon, Martin Nørgaard, Claus Svarer, Sofie B Andersen, Martin K Madsen, William F C Baaré, Jacob Madsen, Vibe G Frokjaer, Gitte M Knudse. Seasonality-resilient individuals downregulate their cerebral 5-HT transporter binding in winter - A longitudinal combined European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 10. 2019-06-03. PMID:30077433. |
seasonality-resilient individuals downregulate their cerebral 5-ht transporter binding in winter - a longitudinal combined we have recently shown that the emergence and severity of seasonal affective disorder (sad) symptoms in the winter is associated with an increase in cerebral serotonin (5-ht) transporter (sert) binding. |
2019-06-03 |
2023-08-13 |
Not clear |
| Anouk Schrantee, Paul J Lucassen, Jan Booij, Liesbeth Renema. Serotonin transporter occupancy by the SSRI citalopram predicts default-mode network connectivity. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 10. 2019-06-03. PMID:30082141. |
therefore, we investigated the association between serotonin transporter (sert) occupancy by the selective serotonin reuptake inhibitor citalopram and dmn functional connectivity. |
2019-06-03 |
2023-08-13 |
human |
| Adam Henke, Yekaterina Kovalyova, Matthew Dunn, Dominik Dreier, Niko G Gubernator, Iva Dincheva, Christopher Hwu, Peter Šebej, Mark S Ansorge, David Sulzer, Dalibor Same. Toward Serotonin Fluorescent False Neurotransmitters: Development of Fluorescent Dual Serotonin and Vesicular Monoamine Transporter Substrates for Visualizing Serotonin Neurons. ACS chemical neuroscience. vol 9. issue 5. 2019-05-21. PMID:29281252. |
a systematic structure-activity study revealed the basic structural chemotype of aminoalkyl acridones required for serotonin transporter (sert) activity and enabled lowering the background labeling of these probes while maintaining sert activity, which proved essential for obtaining sufficient signal in the brain tissue (ffn246). |
2019-05-21 |
2023-08-13 |
mouse |
| Verena Burtscher, Matej Hotka, Yang Li, Michael Freissmuth, Walter Sandtne. A label-free approach to detect ligand binding to cell surface proteins in real time. eLife. vol 7. 2019-05-15. PMID:29697048. |
here, we describe a novel type of current by using the serotonin transporter (sert) as a model. |
2019-05-15 |
2023-08-13 |
Not clear |
| Rebecca L Brindley, Mary Beth Bauer, L Anne Walker, Meagan A Quinlan, Ana M D Carneiro, Ji-Ying Sze, Randy D Blakely, Kevin P M Curri. Adrenal serotonin derives from accumulation by the antidepressant-sensitive serotonin transporter. Pharmacological research. vol 140. 2019-05-13. PMID:29894763. |
deletion of the serotonin (5-ht) transporter (sert) gene in mice (sert |
2019-05-13 |
2023-08-13 |
mouse |
| Anthonya Cooper, Donna Woulfe, Fusun Kili. Post-translational modifications of serotonin transporter. Pharmacological research. vol 140. 2019-05-13. PMID:30394319. |
the serotonin transporter (sert) is an oligomeric glycoprotein with two sialic acid residues on each of two complex oligosaccharide molecules. |
2019-05-13 |
2023-08-13 |
Not clear |
| Anthonya Cooper, Donna Woulfe, Fusun Kili. Post-translational modifications of serotonin transporter. Pharmacological research. vol 140. 2019-05-13. PMID:30394319. |
this review discusses the post-translational modifications and their importance on the structure, maturation, and serotonin (5-ht) uptake ability of sert. |
2019-05-13 |
2023-08-13 |
Not clear |