| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Çalıskan, M Gamsızkan, G Açıkgöz, M Durmuş, S Toklu, A Doğrul, A Kurt, M Tunc. Intralesional treatments for hypertrophic scars: comparison among corticosteroid, 5-fluorouracil and botulinum toxin in rabbit ear hypertrophic scar model. European review for medical and pharmacological sciences. vol 20. issue 8. 2017-07-24. PMID:27160135. |
intralesional treatments for hypertrophic scars: comparison among corticosteroid, 5-fluorouracil and botulinum toxin in rabbit ear hypertrophic scar model. |
2017-07-24 |
2023-08-13 |
rabbit |
| E Çalıskan, M Gamsızkan, G Açıkgöz, M Durmuş, S Toklu, A Doğrul, A Kurt, M Tunc. Intralesional treatments for hypertrophic scars: comparison among corticosteroid, 5-fluorouracil and botulinum toxin in rabbit ear hypertrophic scar model. European review for medical and pharmacological sciences. vol 20. issue 8. 2017-07-24. PMID:27160135. |
in order to minimize the variables affecting scar formation, standardized wounds in rabbit ear hypertrophic scar model was used. |
2017-07-24 |
2023-08-13 |
rabbit |
| Liang Guo, Kai Xu, Hongbo Yan, Haifeng Feng, Tao Wang, Linlin Chai, Guozheng X. MicroRNA expression signature and the therapeutic effect of the microRNA‑21 antagomir in hypertrophic scarring. Molecular medicine reports. vol 15. issue 3. 2017-07-13. PMID:28075443. |
of the mirnas identified, mirna‑21 (mir‑21) was significantly increased in hs tissues and hypertrophic scar fibroblasts (hsfbs) as determined by reverse transcription‑quantitative polymerase chain reaction analysis. |
2017-07-13 |
2023-08-13 |
rabbit |
| Shu-Chung Hsieh, Chun-Chi Wu, Shih-Lan Hsu, Jung-Hsing Ye. Molecular mechanisms of gallic acid-induced growth inhibition, apoptosis, and necrosis in hypertrophic scar fibroblasts. Life sciences. vol 179. 2017-06-29. PMID:27515506. |
molecular mechanisms of gallic acid-induced growth inhibition, apoptosis, and necrosis in hypertrophic scar fibroblasts. |
2017-06-29 |
2023-08-13 |
Not clear |
| Shu-Chung Hsieh, Chun-Chi Wu, Shih-Lan Hsu, Jung-Hsing Ye. Molecular mechanisms of gallic acid-induced growth inhibition, apoptosis, and necrosis in hypertrophic scar fibroblasts. Life sciences. vol 179. 2017-06-29. PMID:27515506. |
to explore the effect and molecular mechanism of gallic acid (ga) on the cytostatic and cytotoxicity of hypertrophic scar fibroblasts (hsfs). |
2017-06-29 |
2023-08-13 |
Not clear |
| Kaiyan Xiao, Xusong Luo, Xiuxia Wang, Zhen Ga. MicroRNA‑185 regulates transforming growth factor‑β1 and collagen‑1 in hypertrophic scar fibroblasts. Molecular medicine reports. vol 15. issue 4. 2017-06-19. PMID:28259900. |
microrna‑185 regulates transforming growth factor‑β1 and collagen‑1 in hypertrophic scar fibroblasts. |
2017-06-19 |
2023-08-13 |
Not clear |
| Jingdong Guo, Quan Lin, Ying Shao, Li Rong, Duo Zhan. miR-29b promotes skin wound healing and reduces excessive scar formation by inhibition of the TGF-β1/Smad/CTGF signaling pathway. Canadian journal of physiology and pharmacology. vol 95. issue 4. 2017-06-06. PMID:28092445. |
the hypertrophic scar is a medical difficulty of humans, which has caused great pain to patients. |
2017-06-06 |
2023-08-13 |
mouse |
| Jingdong Guo, Quan Lin, Ying Shao, Li Rong, Duo Zhan. miR-29b promotes skin wound healing and reduces excessive scar formation by inhibition of the TGF-β1/Smad/CTGF signaling pathway. Canadian journal of physiology and pharmacology. vol 95. issue 4. 2017-06-06. PMID:28092445. |
taken together, our data suggest that mir-29b treatment has an inhibitory effect against scar formation via inhibition of the tgf-β1/smad/ctgf signaling pathway and may provide a potential molecular basis for future treatments for hypertrophic scars. |
2017-06-06 |
2023-08-13 |
mouse |
| Deborah Watson, Bharat Panugant. Treating Scars in the Auricle Region. Facial plastic surgery clinics of North America. vol 25. issue 1. 2017-05-22. PMID:27888895. |
the management plan for auricular scarring requires appropriate patient counseling regarding the risk of recurrence in keloids, regrowth of scar tissue in cauliflower ears, scar hypertrophy at the line of closure, widening of the scar, and persisting ear contour deformities. |
2017-05-22 |
2023-08-13 |
Not clear |
| Guangzao Li, Renpeng Zhou, Qi Zhang, Banghong Jiang, Qingkai Wu, Chen Wan. Fibroproliferative effect of microRNA-21 in hypertrophic scar derived fibroblasts. Experimental cell research. vol 345. issue 1. 2017-05-15. PMID:27207585. |
fibroproliferative effect of microrna-21 in hypertrophic scar derived fibroblasts. |
2017-05-15 |
2023-08-13 |
mouse |
| Guangzao Li, Renpeng Zhou, Qi Zhang, Banghong Jiang, Qingkai Wu, Chen Wan. Fibroproliferative effect of microRNA-21 in hypertrophic scar derived fibroblasts. Experimental cell research. vol 345. issue 1. 2017-05-15. PMID:27207585. |
hypertrophic scar (hs) is a fibroproliferative disorder caused by abnormal wound healing, which is characterized by excessive deposition of extracellular matrix (ecm) secreted by fibroblasts. |
2017-05-15 |
2023-08-13 |
mouse |
| Guangzao Li, Renpeng Zhou, Qi Zhang, Banghong Jiang, Qingkai Wu, Chen Wan. Fibroproliferative effect of microRNA-21 in hypertrophic scar derived fibroblasts. Experimental cell research. vol 345. issue 1. 2017-05-15. PMID:27207585. |
in addition, the mir-21 inhibitor inhibited the growth of hypertrophic scar tissue in vivo (nude mice experimental model). |
2017-05-15 |
2023-08-13 |
mouse |
| C Michael DiPersio, Rui Zheng, James Kenney, Livingston Van De Wate. Integrin-mediated regulation of epidermal wound functions. Cell and tissue research. vol 365. issue 3. 2017-05-15. PMID:27351421. |
importantly, it is likely that abnormal integrin expression or function in the epidermis contributes to wound pathologies such as over-exuberant healing (e.g., hypertrophic scar formation) or diminished healing (e.g., chronic wounds). |
2017-05-15 |
2023-08-13 |
Not clear |
| Xin Li, Zizhong Liu, Houfang Liu, Xi Chen, Yue Liu, Honglue Ta. Photodynamic inactivation of fibroblasts and inhibition of Staphylococcus epidermidis adhesion and biofilm formation by toluidine blue O. Molecular medicine reports. vol 15. issue 4. 2017-05-12. PMID:28259957. |
these results indicate that the local use of tbo‑pdt in limb lesions may be a useful treatment method for inhibiting bacterial biofilm formation and fibroblastic hyperproliferation, which may prevent infectious hypertrophic scar formation. |
2017-05-12 |
2023-08-13 |
human |
| Guillermo Ramos-Gallardo, Ariel Miranda-Altamirano, Rebeca Valdes-López, Sandra Figueroa-Jiménez, Leonel García-Benavide. [Verapamil in conjunction with pressure therapy in the treatment of pathologic scar due burn injury]. Revista medica del Instituto Mexicano del Seguro Social. vol 54. issue 4. 2017-05-03. PMID:27197102. |
the aim of this article is to evaluate the use of verapamil and pressure garments in patients with hypertrophic or keloid scar caused by burn injury. |
2017-05-03 |
2023-08-13 |
Not clear |
| Fengjun Fang, Ru-Lin Huang, Yongchao Zheng, Ming Liu, Ran Hu. Bone marrow derived mesenchymal stem cells inhibit the proliferative and profibrotic phenotype of hypertrophic scar fibroblasts and keloid fibroblasts through paracrine signaling. Journal of dermatological science. vol 83. issue 2. 2017-05-02. PMID:27211019. |
bone marrow derived mesenchymal stem cells inhibit the proliferative and profibrotic phenotype of hypertrophic scar fibroblasts and keloid fibroblasts through paracrine signaling. |
2017-05-02 |
2023-08-13 |
Not clear |
| Elif Sari, Bulent Bakar, Gungor Cagdas Dincel, Fatma Azize Budak Yildira. Effects of DMSO on a rabbit ear hypertrophic scar model: A controlled randomized experimental study. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. vol 70. issue 4. 2017-04-21. PMID:28216321. |
effects of dmso on a rabbit ear hypertrophic scar model: a controlled randomized experimental study. |
2017-04-21 |
2023-08-13 |
rabbit |
| Elif Sari, Bulent Bakar, Gungor Cagdas Dincel, Fatma Azize Budak Yildira. Effects of DMSO on a rabbit ear hypertrophic scar model: A controlled randomized experimental study. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. vol 70. issue 4. 2017-04-21. PMID:28216321. |
this study aimed to investigate the possible therapeutic effects of dmso on hypertrophic scar formation in rabbits. |
2017-04-21 |
2023-08-13 |
rabbit |
| Elif Sari, Bulent Bakar, Gungor Cagdas Dincel, Fatma Azize Budak Yildira. Effects of DMSO on a rabbit ear hypertrophic scar model: A controlled randomized experimental study. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. vol 70. issue 4. 2017-04-21. PMID:28216321. |
following the hypertrophic scar formation on day 28, intralesional dmso and triamcinolone acetonide were administered once a week for 4 weeks into these scars of the dmso and tra groups, respectively. |
2017-04-21 |
2023-08-13 |
rabbit |
| Elif Sari, Bulent Bakar, Gungor Cagdas Dincel, Fatma Azize Budak Yildira. Effects of DMSO on a rabbit ear hypertrophic scar model: A controlled randomized experimental study. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. vol 70. issue 4. 2017-04-21. PMID:28216321. |
on the basis of the results, it can be concluded that intralesional administration of dmso decreases hypertrophic scar formation easily and safely. |
2017-04-21 |
2023-08-13 |
rabbit |