| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ruixia Kuang, Zhiguo Wang, Quanchen Xu, Xia Cai, Tao Li. Exposure to Varying Strain Magnitudes Influences the Conversion of Normal Skin Fibroblasts Into Hypertrophic Scar Cells. Annals of plastic surgery. vol 76. issue 4. 2016-12-22. PMID:26545222. |
cultured fibroblasts isolated from hypertrophic scar and normal skin tissue were subjected to cyclic mechanical stretching under individual 10%, 15%, and 20% strain magnitudes at a frequency of 0.1 hz for 24 hours. |
2016-12-22 |
2023-08-13 |
human |
| Ruixia Kuang, Zhiguo Wang, Quanchen Xu, Xia Cai, Tao Li. Exposure to Varying Strain Magnitudes Influences the Conversion of Normal Skin Fibroblasts Into Hypertrophic Scar Cells. Annals of plastic surgery. vol 76. issue 4. 2016-12-22. PMID:26545222. |
the demonstrable conversion of normal skin fibroblasts into hypertrophic scar fibroblasts was also observed when 10% stretching magnitude was applied to cultured fibroblasts in vitro. |
2016-12-22 |
2023-08-13 |
human |
| Ying-ying Xiao, Peng-ju Fan, Shao-rong Lei, Min Qi, Xing-hua Yan. MiR-138/peroxisome proliferator-activated receptor β signaling regulates human hypertrophic scar fibroblast proliferation and movement in vitro. The Journal of dermatology. vol 42. issue 5. 2016-12-13. PMID:25752881. |
mir-138/peroxisome proliferator-activated receptor β signaling regulates human hypertrophic scar fibroblast proliferation and movement in vitro. |
2016-12-13 |
2023-08-13 |
human |
| Ying-ying Xiao, Peng-ju Fan, Shao-rong Lei, Min Qi, Xing-hua Yan. MiR-138/peroxisome proliferator-activated receptor β signaling regulates human hypertrophic scar fibroblast proliferation and movement in vitro. The Journal of dermatology. vol 42. issue 5. 2016-12-13. PMID:25752881. |
because there is a poor understanding of the complex mechanisms underlying the processes of hypertrophic scar formation, most therapeutic approaches remain clinically unsatisfactory. |
2016-12-13 |
2023-08-13 |
human |
| Ying-ying Xiao, Peng-ju Fan, Shao-rong Lei, Min Qi, Xing-hua Yan. MiR-138/peroxisome proliferator-activated receptor β signaling regulates human hypertrophic scar fibroblast proliferation and movement in vitro. The Journal of dermatology. vol 42. issue 5. 2016-12-13. PMID:25752881. |
in this study, we found that mir-138 was downregulated and peroxisome proliferator-activated receptor (pparβ) was inversely upregulated in hypertrophic scar tissues compared to in paired normal skin tissues. |
2016-12-13 |
2023-08-13 |
human |
| Ying-ying Xiao, Peng-ju Fan, Shao-rong Lei, Min Qi, Xing-hua Yan. MiR-138/peroxisome proliferator-activated receptor β signaling regulates human hypertrophic scar fibroblast proliferation and movement in vitro. The Journal of dermatology. vol 42. issue 5. 2016-12-13. PMID:25752881. |
in gain-and-loss experiments, we found that mir-138/pparβ signaling regulated human hypertrophic scar fibroblast proliferation and movement, and affected scarring-related protein expression, which suggests that mir-138/pparβ signaling is important for hypertrophic scarring. |
2016-12-13 |
2023-08-13 |
human |
| Y F Zhang, S Z Zhou, X Y Cheng, B Yi, S Z Shan, J Wang, Q F L. Baicalein attenuates hypertrophic scar formation via inhibition of the transforming growth factor-β/Smad2/3 signalling pathway. The British journal of dermatology. vol 174. issue 1. 2016-12-13. PMID:26301336. |
baicalein attenuates hypertrophic scar formation via inhibition of the transforming growth factor-β/smad2/3 signalling pathway. |
2016-12-13 |
2023-08-13 |
Not clear |
| Satishkumar Kolekar, Chandrashekhar Munjewar, Satyavan Sharm. Dabigatran for left ventricular thrombus. Indian heart journal. vol 67. issue 5. 2016-12-13. PMID:26432747. |
male patient in dilated phase of hypertrophic cardiomyopathy had multiple hospitalizations during the past 2 years either due to congestive heart failure, stroke, scar epilepsy, or atrial fibrillation and ventricular tachycardia. |
2016-12-13 |
2023-08-13 |
Not clear |
| Qing-Qing Yang, Si-Si Yang, Jiang-Lin Tan, Gao-Xing Luo, Wei-Feng He, Jun W. Process of Hypertrophic Scar Formation: Expression of Eukaryotic Initiation Factor 6. Chinese medical journal. vol 128. issue 20. 2016-12-13. PMID:26481747. |
process of hypertrophic scar formation: expression of eukaryotic initiation factor 6. |
2016-12-13 |
2023-08-13 |
human |
| Qing-Qing Yang, Si-Si Yang, Jiang-Lin Tan, Gao-Xing Luo, Wei-Feng He, Jun W. Process of Hypertrophic Scar Formation: Expression of Eukaryotic Initiation Factor 6. Chinese medical journal. vol 128. issue 20. 2016-12-13. PMID:26481747. |
hypertrophic scar is one of the most common complications and often causes the disfigurement or deformity in burn or trauma patients. |
2016-12-13 |
2023-08-13 |
human |
| Qing-Qing Yang, Si-Si Yang, Jiang-Lin Tan, Gao-Xing Luo, Wei-Feng He, Jun W. Process of Hypertrophic Scar Formation: Expression of Eukaryotic Initiation Factor 6. Chinese medical journal. vol 128. issue 20. 2016-12-13. PMID:26481747. |
therapeutic methods on hypertrophic scar treatment have limitations due to the poor understanding of mechanisms of hypertrophic scar formation. |
2016-12-13 |
2023-08-13 |
human |
| Qing-Qing Yang, Si-Si Yang, Jiang-Lin Tan, Gao-Xing Luo, Wei-Feng He, Jun W. Process of Hypertrophic Scar Formation: Expression of Eukaryotic Initiation Factor 6. Chinese medical journal. vol 128. issue 20. 2016-12-13. PMID:26481747. |
to throw light on the molecular mechanism of hypertrophic scar formation will definitely improve the outcome of the treatment. |
2016-12-13 |
2023-08-13 |
human |
| Qing-Qing Yang, Si-Si Yang, Jiang-Lin Tan, Gao-Xing Luo, Wei-Feng He, Jun W. Process of Hypertrophic Scar Formation: Expression of Eukaryotic Initiation Factor 6. Chinese medical journal. vol 128. issue 20. 2016-12-13. PMID:26481747. |
this study aimed to illustrate the negative role of eukaryotic initiation factor 6 (eif6) in the process of human hypertrophic scar formation, and provide a possible indicator of hypertrophic scar treatment and a potential target molecule for hypertrophic scar. |
2016-12-13 |
2023-08-13 |
human |
| P Sáez, E Kuh. Computational modeling of acute myocardial infarction. Computer methods in biomechanics and biomedical engineering. vol 19. issue 10. 2016-12-13. PMID:26583449. |
in the later stages, collagenous scar formation in the infarcted zone and hypertrophy of the non-infarcted zone are auto-regulatory mechanisms to partly correct for these events. |
2016-12-13 |
2023-08-13 |
Not clear |
| S A Afanasiev, D S Kondratieva, T Yu Rebrova, R E Batalov, S V Popo. Coupling of the Functional Stability of Rat Myocardium and Activity of Lipid Peroxidation in Combined Development of Postinfarction Remodeling and Diabetes Mellitus. Journal of diabetes research. vol 2016. 2016-12-13. PMID:26844230. |
the functional stability of myocardium was studied by means of the analysis of inotropic reaction on extrasystolic stimulus, the degree of left ventricular hypertrophy, and the size of scar zone. |
2016-12-13 |
2023-08-13 |
rat |
| P Ning, Y Peng, D W Liu, Y H Hu, Y Liu, D M Li. Tetrandrine induces microRNA differential expression in human hypertrophic scar fibroblasts in vitro. Genetics and molecular research : GMR. vol 15. issue 1. 2016-11-14. PMID:26909951. |
tetrandrine induces microrna differential expression in human hypertrophic scar fibroblasts in vitro. |
2016-11-14 |
2023-08-13 |
human |
| P Ning, Y Peng, D W Liu, Y H Hu, Y Liu, D M Li. Tetrandrine induces microRNA differential expression in human hypertrophic scar fibroblasts in vitro. Genetics and molecular research : GMR. vol 15. issue 1. 2016-11-14. PMID:26909951. |
this study aimed to explore the effects of tetrandrine on the mirna expression profile in human hypertrophic scar fibroblasts (hsfs) in vitro. |
2016-11-14 |
2023-08-13 |
human |
| J Shi, H Wang, H Guan, S Shi, Y Li, X Wu, N Li, C Yang, X Bai, W Cai, F Yang, X Wang, L Su, Z Zheng, D H. IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathways. Cell death & disease. vol 7. 2016-11-14. PMID:26962683. |
il10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the il10-il10r-stat3 and il10-akt-mtor pathways. |
2016-11-14 |
2023-08-13 |
Not clear |
| J Shi, H Wang, H Guan, S Shi, Y Li, X Wu, N Li, C Yang, X Bai, W Cai, F Yang, X Wang, L Su, Z Zheng, D H. IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathways. Cell death & disease. vol 7. 2016-11-14. PMID:26962683. |
hypertrophic scar (hs) is a serious skin fibrotic disease characterized by excessive hypercellularity and extracellular matrix (ecm) component deposition. |
2016-11-14 |
2023-08-13 |
Not clear |
| Elizabeth R Lorden, Kyle J Miller, Mohamed M Ibrahim, Latif Bashirov, Ellen Hammett, Syandan Chakraborty, Carlos Quiles-Torres, M Angelica Selim, Kam W Leong, Howard Levinso. Biostable electrospun microfibrous scaffolds mitigate hypertrophic scar contraction in an immune-competent murine model. Acta biomaterialia. vol 32. 2016-11-07. PMID:26708709. |
biostable electrospun microfibrous scaffolds mitigate hypertrophic scar contraction in an immune-competent murine model. |
2016-11-07 |
2023-08-13 |
Not clear |