| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiao Wei, Cheng-An Chiang, Da Zhou, Qingfeng Li, Kai Li. Domino Flaps for Repairing of Secondary Bilateral Cleft Lip With Severe Columella Deformity. The Journal of craniofacial surgery. vol 28. issue 1. 2018-02-01. PMID:27875514. |
among them, 3 of the patients got hypertrophic scar on the upper lip and were modified 1 year after their first operations. |
2018-02-01 |
2023-08-13 |
Not clear |
| Liselotte Butzelaar, Dennis P M Schooneman, Ezgi A Soykan, Wendy Talhout, Magda M W Ulrich, Lenie J van den Broek, Susan Gibbs, Robert H J Beelen, Aebele B Mink van der Molen, Frank B Niesse. Inhibited early immunologic response is associated with hypertrophic scarring. Experimental dermatology. vol 25. issue 10. 2018-01-30. PMID:27249786. |
the immune system is thought to be involved in hypertrophic scar formation. |
2018-01-30 |
2023-08-13 |
Not clear |
| Liselotte Butzelaar, Dennis P M Schooneman, Ezgi A Soykan, Wendy Talhout, Magda M W Ulrich, Lenie J van den Broek, Susan Gibbs, Robert H J Beelen, Aebele B Mink van der Molen, Frank B Niesse. Inhibited early immunologic response is associated with hypertrophic scarring. Experimental dermatology. vol 25. issue 10. 2018-01-30. PMID:27249786. |
the endpoint was scar outcome (hypertrophic (hts) or normal (nts)) at one year after surgery. |
2018-01-30 |
2023-08-13 |
Not clear |
| Daniël C Koppenol, Fred J Vermolen, Frank B Niessen, Paul P M van Zuijlen, Kees Vui. A mathematical model for the simulation of the formation and the subsequent regression of hypertrophic scar tissue after dermal wounding. Biomechanics and modeling in mechanobiology. vol 16. issue 1. 2018-01-26. PMID:27229739. |
a mathematical model for the simulation of the formation and the subsequent regression of hypertrophic scar tissue after dermal wounding. |
2018-01-26 |
2023-08-13 |
human |
| Daniël C Koppenol, Fred J Vermolen, Frank B Niessen, Paul P M van Zuijlen, Kees Vui. A mathematical model for the simulation of the formation and the subsequent regression of hypertrophic scar tissue after dermal wounding. Biomechanics and modeling in mechanobiology. vol 16. issue 1. 2018-01-26. PMID:27229739. |
a continuum hypothesis-based model is presented for the simulation of the formation and the subsequent regression of hypertrophic scar tissue after dermal wounding. |
2018-01-26 |
2023-08-13 |
human |
| Daniël C Koppenol, Fred J Vermolen, Frank B Niessen, Paul P M van Zuijlen, Kees Vui. A mathematical model for the simulation of the formation and the subsequent regression of hypertrophic scar tissue after dermal wounding. Biomechanics and modeling in mechanobiology. vol 16. issue 1. 2018-01-26. PMID:27229739. |
interestingly, the comparison between the outcomes of the simulations and the clinical measurements demonstrates that a relatively high apoptosis rate of myofibroblasts results in scar tissue that behaves more like normal scar tissue with respect to the evolution of the thickness of the tissue over time, while a relatively low apoptosis rate results in scar tissue that behaves like hypertrophic scar tissue with respect to the evolution of the thickness of the tissue over time. |
2018-01-26 |
2023-08-13 |
human |
| Jingling Zhao, Bin Shu, Lei Chen, Jinming Tang, Lijun Zhang, Julin Xie, Xusheng Liu, Yingbin Xu, Shaohai Q. Prostaglandin E2 inhibits collagen synthesis in dermal fibroblasts and prevents hypertrophic scar formation in vivo. Experimental dermatology. vol 25. issue 8. 2018-01-25. PMID:26997546. |
prostaglandin e2 inhibits collagen synthesis in dermal fibroblasts and prevents hypertrophic scar formation in vivo. |
2018-01-25 |
2023-08-13 |
Not clear |
| Jingling Zhao, Bin Shu, Lei Chen, Jinming Tang, Lijun Zhang, Julin Xie, Xusheng Liu, Yingbin Xu, Shaohai Q. Prostaglandin E2 inhibits collagen synthesis in dermal fibroblasts and prevents hypertrophic scar formation in vivo. Experimental dermatology. vol 25. issue 8. 2018-01-25. PMID:26997546. |
an in vivo study further confirmed that pge2 inhibits hypertrophic scar formation by decreasing collagen production. |
2018-01-25 |
2023-08-13 |
Not clear |
| Shuting Fan, Benjamin S Y Ung, Edward P J Parrott, Vincent P Wallace, Emma Pickwell-MacPherso. In vivo terahertz reflection imaging of human scars during and after the healing process. Journal of biophotonics. vol 10. issue 9. 2018-01-09. PMID:27804226. |
additionally, we monitored the healing process of a hypertrophic scar. |
2018-01-09 |
2023-08-13 |
human |
| Ilkka Kaartine. Treatment of hypertrophic scars and keloids. Duodecim; laaketieteellinen aikakauskirja. vol 132. issue 16. 2018-01-08. PMID:29188931. |
differentiation of a hypertrophic scar from a keloid is important with regard to the planning of treatment. |
2018-01-08 |
2023-08-13 |
Not clear |
| Ilkka Kaartine. Treatment of hypertrophic scars and keloids. Duodecim; laaketieteellinen aikakauskirja. vol 132. issue 16. 2018-01-08. PMID:29188931. |
treatment of hypertrophic scars aims to abate the symptoms and accelerate scar maturation. |
2018-01-08 |
2023-08-13 |
Not clear |
| Qingwen Nong, Shuntang Li, Yajun Wu, Daen Li. LncRNA COL1A2-AS1 inhibits the scar fibroblasts proliferation via regulating miR-21/Smad7 pathway. Biochemical and biophysical research communications. vol 495. issue 1. 2017-12-29. PMID:29117538. |
lncrna col1a2-as1 (col1a2 antisense rna 1), a lncrna overexpressed in hypertrophic scar, has been demonstrated to be involved in the hypertrophic scar formation. |
2017-12-29 |
2023-08-13 |
Not clear |
| Qingwen Nong, Shuntang Li, Yajun Wu, Daen Li. LncRNA COL1A2-AS1 inhibits the scar fibroblasts proliferation via regulating miR-21/Smad7 pathway. Biochemical and biophysical research communications. vol 495. issue 1. 2017-12-29. PMID:29117538. |
in this study, we demonstrated that lncrna col1a2-as1 was upregulated in hypertrophic scar tissue and fibroblasts, and suppressed fibroblasts proliferation by promoting smad7 expression. |
2017-12-29 |
2023-08-13 |
Not clear |
| Qingwen Nong, Shuntang Li, Yajun Wu, Daen Li. LncRNA COL1A2-AS1 inhibits the scar fibroblasts proliferation via regulating miR-21/Smad7 pathway. Biochemical and biophysical research communications. vol 495. issue 1. 2017-12-29. PMID:29117538. |
furthermore, we found that mir-21 was involved in lncrna col1a2-as1-induced expression of smad7, by which col1a2-as1 acted as endogenous sponge to adsorb mir-21 and in turn regulated smad7 and a cascade of molecular to play a protective role in hypertrophic scar. |
2017-12-29 |
2023-08-13 |
Not clear |
| Qingwen Nong, Shuntang Li, Yajun Wu, Daen Li. LncRNA COL1A2-AS1 inhibits the scar fibroblasts proliferation via regulating miR-21/Smad7 pathway. Biochemical and biophysical research communications. vol 495. issue 1. 2017-12-29. PMID:29117538. |
in addition, overexpression of mir-21 attenuated col1a2-as1-mediated proliferation suppression of hypertrophic scar fibroblasts. |
2017-12-29 |
2023-08-13 |
Not clear |
| Qingwen Nong, Shuntang Li, Yajun Wu, Daen Li. LncRNA COL1A2-AS1 inhibits the scar fibroblasts proliferation via regulating miR-21/Smad7 pathway. Biochemical and biophysical research communications. vol 495. issue 1. 2017-12-29. PMID:29117538. |
in conclusion, our study demonstrated that col1a2-as1/mir-21/smad pathway plays an important role in inhibiting hypertrophic scar formation, and suggested this novel pathway may be a new target for hypertrophic scar treatment. |
2017-12-29 |
2023-08-13 |
Not clear |
| F Kuang, Z Zhang, B Chen, C L Liu, Y Y Zhao, Z R Xu, X J L. [The expression of SnoN in human hypertrophic scar fibroblasts and the mechanism of its participation in hypertrophic scar formation]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 33. issue 10. 2017-12-08. PMID:29056026. |
[the expression of snon in human hypertrophic scar fibroblasts and the mechanism of its participation in hypertrophic scar formation]. |
2017-12-08 |
2023-08-13 |
human |
| Sheng Bi, Linlin Chai, Xi Yuan, Chuan Cao, Shirong L. MicroRNA-98 inhibits the cell proliferation of human hypertrophic scar fibroblasts via targeting Col1A1. Biological research. vol 50. issue 1. 2017-12-04. PMID:28629444. |
microrna-98 inhibits the cell proliferation of human hypertrophic scar fibroblasts via targeting col1a1. |
2017-12-04 |
2023-08-13 |
human |
| Sheng Bi, Linlin Chai, Xi Yuan, Chuan Cao, Shirong L. MicroRNA-98 inhibits the cell proliferation of human hypertrophic scar fibroblasts via targeting Col1A1. Biological research. vol 50. issue 1. 2017-12-04. PMID:28629444. |
col1a1 could promote the hypertrophic scar formation, and the expression of col1a1 in hs tissue was markedly higher than that in the normal. |
2017-12-04 |
2023-08-13 |
human |
| X Wang, Y Zhang, B H Jiang, Q Zhang, R P Zhou, L Zhang, Chen Wan. Study on the role of Hsa-miR-31-5p in hypertrophic scar formation and the mechanism. Experimental cell research. vol 361. issue 2. 2017-11-29. PMID:29056521. |
study on the role of hsa-mir-31-5p in hypertrophic scar formation and the mechanism. |
2017-11-29 |
2023-08-13 |
Not clear |