| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sasithorn Suda, Helen Williams, Heather J Medbury, Andrew J A Hollan. A Review of Monocytes and Monocyte-Derived Cells in Hypertrophic Scarring Post Burn. Journal of burn care & research : official publication of the American Burn Association. vol 37. issue 5. 2018-03-05. PMID:27003739. |
the formation of the hypertrophic scar arises from excessive production of collagen during wound healing. |
2018-03-05 |
2023-08-13 |
Not clear |
| Linlin Su, Lanqing Fu, Yan Li, Fangfang Yang, Min Zhang, Dahai H. Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. Oncotarget. vol 8. issue 2. 2018-03-05. PMID:27926506. |
disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. |
2018-03-05 |
2023-08-13 |
Not clear |
| Linlin Su, Lanqing Fu, Yan Li, Fangfang Yang, Min Zhang, Dahai H. Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. Oncotarget. vol 8. issue 2. 2018-03-05. PMID:27926506. |
hypertrophic scar is characterized by the overgrowth of fibroblasts and often considered as a kind of benign skin tumor, thus chemotherapeutic drugs have been used to treat scars. |
2018-03-05 |
2023-08-13 |
Not clear |
| Linlin Su, Lanqing Fu, Yan Li, Fangfang Yang, Min Zhang, Dahai H. Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. Oncotarget. vol 8. issue 2. 2018-03-05. PMID:27926506. |
in view of the similarity, this study aims to investigate whether drug resistance in cancer that contributes to the failure of chemotherapy also exists in hypertrophic scar, and what is the possible mechanism. |
2018-03-05 |
2023-08-13 |
Not clear |
| Linlin Su, Lanqing Fu, Yan Li, Fangfang Yang, Min Zhang, Dahai H. Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. Oncotarget. vol 8. issue 2. 2018-03-05. PMID:27926506. |
fibroblasts derived from hypertrophic scar and normal skin tissues were first compared for their resistance to verapamil and etoposide phosphate. |
2018-03-05 |
2023-08-13 |
Not clear |
| Linlin Su, Lanqing Fu, Yan Li, Fangfang Yang, Min Zhang, Dahai H. Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. Oncotarget. vol 8. issue 2. 2018-03-05. PMID:27926506. |
taken together, this study suggests that the enhanced expression of drug resistance-related transporters and their increased association with actin cytoskeleton contribute to the resistance to chemotherapeutic drugs in hypertrophic scar. |
2018-03-05 |
2023-08-13 |
Not clear |
| Linlin Su, Lanqing Fu, Yan Li, Fangfang Yang, Min Zhang, Dahai H. Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. Oncotarget. vol 8. issue 2. 2018-03-05. PMID:27926506. |
thus, down-regulating the expession of drug transporters or disrupting drug transporter-actin filament interaction might be novel and effective ways for hypertrophic scar treatment. |
2018-03-05 |
2023-08-13 |
Not clear |
| Peter O Kwan, Jie Ding, Edward E Tredge. Serum Decorin, Interleukin-1β, and Transforming Growth Factor-β Predict Hypertrophic Scarring Postburn. Journal of burn care & research : official publication of the American Burn Association. vol 37. issue 6. 2018-03-02. PMID:27828834. |
hypertrophic scar after burn injury is a significant problem. |
2018-03-02 |
2023-08-13 |
Not clear |
| Peter O Kwan, Jie Ding, Edward E Tredge. Serum Decorin, Interleukin-1β, and Transforming Growth Factor-β Predict Hypertrophic Scarring Postburn. Journal of burn care & research : official publication of the American Burn Association. vol 37. issue 6. 2018-03-02. PMID:27828834. |
previous studies have examined the roles for decorin, interleukin-1β, and transforming growth factor-β1 in hypertrophic scar formation locally, but few have considered their systemic influence. |
2018-03-02 |
2023-08-13 |
Not clear |
| Peter O Kwan, Jie Ding, Edward E Tredge. Serum Decorin, Interleukin-1β, and Transforming Growth Factor-β Predict Hypertrophic Scarring Postburn. Journal of burn care & research : official publication of the American Burn Association. vol 37. issue 6. 2018-03-02. PMID:27828834. |
the authors conducted a pilot study to examine whether serum levels of these molecules could predict hypertrophic scar formation. |
2018-03-02 |
2023-08-13 |
Not clear |
| Peter O Kwan, Jie Ding, Edward E Tredge. Serum Decorin, Interleukin-1β, and Transforming Growth Factor-β Predict Hypertrophic Scarring Postburn. Journal of burn care & research : official publication of the American Burn Association. vol 37. issue 6. 2018-03-02. PMID:27828834. |
serum levels were measured using enzyme-linked immunosorbent assay, and hypertrophic scar formation determined from chart reviews. |
2018-03-02 |
2023-08-13 |
Not clear |
| Peter O Kwan, Jie Ding, Edward E Tredge. Serum Decorin, Interleukin-1β, and Transforming Growth Factor-β Predict Hypertrophic Scarring Postburn. Journal of burn care & research : official publication of the American Burn Association. vol 37. issue 6. 2018-03-02. PMID:27828834. |
multiple linear regression analysis suggested early serum levels of decorin and interleukin-1β, and late serum levels of transforming growth factor-β1 were predictive of hypertrophic scar formation. |
2018-03-02 |
2023-08-13 |
Not clear |
| Peter O Kwan, Jie Ding, Edward E Tredge. Serum Decorin, Interleukin-1β, and Transforming Growth Factor-β Predict Hypertrophic Scarring Postburn. Journal of burn care & research : official publication of the American Burn Association. vol 37. issue 6. 2018-03-02. PMID:27828834. |
the model predicting hypertrophic scar formation is supported by clinical results and limited in vitro experiments. |
2018-03-02 |
2023-08-13 |
Not clear |
| Patricia A Sharp, Brian Pan, Kevin P Yakuboff, Dawn Rothchil. Development of a Best Evidence Statement for the Use of Pressure Therapy for Management of Hypertrophic Scarring. Journal of burn care & research : official publication of the American Burn Association. vol 37. issue 4. 2018-03-01. PMID:26056760. |
search terms included scar, hypertroph*, pressure therapy, compression therapy, pressure garment, burn, scald, trauma as well as mesh terms cicatrix and hypertrophic. |
2018-03-01 |
2023-08-13 |
Not clear |
| Patricia A Sharp, Brian Pan, Kevin P Yakuboff, Dawn Rothchil. Development of a Best Evidence Statement for the Use of Pressure Therapy for Management of Hypertrophic Scarring. Journal of burn care & research : official publication of the American Burn Association. vol 37. issue 4. 2018-03-01. PMID:26056760. |
among individuals with or at risk to develop active hypertrophic scars, treatment with pressure therapy does improve outcomes, particularly for aesthetic concerns including scar thickness and erythema. |
2018-03-01 |
2023-08-13 |
Not clear |
| Lisa Macintyre, Monali Dahale, Michelle Ra. Impact of Moisture on the Pressure Delivering Potential of Pressure Garments. Journal of burn care & research : official publication of the American Burn Association. vol 37. issue 4. 2018-03-01. PMID:26171677. |
the pressure they exert on the scarred skin prevents contractures forming, reduces the itchiness and pruritus associated with active hypertrophic scars, and is believed, by many, to hasten normalization of the scar tissue. |
2018-03-01 |
2023-08-13 |
Not clear |
| Bonnie C Carney, Zekun Liu, Abdulnaser Alkhalil, Taryn E Travis, Jessica Ramella-Roman, Lauren T Moffatt, Jeffrey W Shup. Elastin Is Differentially Regulated by Pressure Therapy in a Porcine Model of Hypertrophic Scar. Journal of burn care & research : official publication of the American Burn Association. vol 38. issue 1. 2018-02-21. PMID:28009695. |
elastin is differentially regulated by pressure therapy in a porcine model of hypertrophic scar. |
2018-02-21 |
2023-08-13 |
Not clear |
| Li-Wu Qian, Andrea B Fourcaudot, Kai P Leun. Silver Sulfadiazine Retards Wound Healing and Increases Hypertrophic Scarring in a Rabbit Ear Excisional Wound Model. Journal of burn care & research : official publication of the American Burn Association. vol 38. issue 1. 2018-02-21. PMID:28009700. |
at pod 28, when compared to the base cream-treated group (1.44 ± 0.03), ssd-treated-groups (0.1 and 1%) had more (p < .05) hypertrophic scar formation (scar elevation index = 1.65 ± 0.04, 0.1%; 1.63 ± 0.06, 1%). |
2018-02-21 |
2023-08-13 |
rabbit |
| Li-Wu Qian, Andrea B Fourcaudot, Kai P Leun. Silver Sulfadiazine Retards Wound Healing and Increases Hypertrophic Scarring in a Rabbit Ear Excisional Wound Model. Journal of burn care & research : official publication of the American Burn Association. vol 38. issue 1. 2018-02-21. PMID:28009700. |
the results of this study demonstrate that ssd treatment contributes not only to impaired reepithelialization but also to a greater hypertrophic scar formation. |
2018-02-21 |
2023-08-13 |
rabbit |
| Drew Del Toro, Raj Dedhia, Travis T Tollefso. Advances in scar management: prevention and management of hypertrophic scars and keloids. Current opinion in otolaryngology & head and neck surgery. vol 24. issue 4. 2018-02-07. PMID:27163611. |
advances in scar management: prevention and management of hypertrophic scars and keloids. |
2018-02-07 |
2023-08-13 |
Not clear |