| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nihui Zhang, Tao Gao, Yao Wang, Juan Liu, Junwei Zhang, Ruijuan Yao, Fang W. Modulating cationicity of chitosan hydrogel to prevent hypertrophic scar formation during wound healing. International journal of biological macromolecules. vol 154. 2021-02-19. PMID:32194120. |
it is of great clinical significance to design wound dressing materials with combined excellent wound healing properties and superior capability to suppress hypertrophic scar formation. |
2021-02-19 |
2023-08-13 |
Not clear |
| Nihui Zhang, Tao Gao, Yao Wang, Juan Liu, Junwei Zhang, Ruijuan Yao, Fang W. Modulating cationicity of chitosan hydrogel to prevent hypertrophic scar formation during wound healing. International journal of biological macromolecules. vol 154. 2021-02-19. PMID:32194120. |
an optimum window of chitosan cationicity (5% in our case) demonstrated potential to mitigate hypertrophic scar in wound healing by suppressing the expression of a-smooth muscle actin (a-sma) and promoting secretion of type i matrix metalloproteinases (mmp-1). |
2021-02-19 |
2023-08-13 |
Not clear |
| Tianya Li, Wei Chen, Qun Zhang, Chenliang Den. Human-specific gene CHRFAM7A mediates M2 macrophage polarization via the Notch pathway to ameliorate hypertrophic scar formation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 131. 2021-02-17. PMID:32890966. |
human-specific gene chrfam7a mediates m2 macrophage polarization via the notch pathway to ameliorate hypertrophic scar formation. |
2021-02-17 |
2023-08-13 |
mouse |
| Tianya Li, Wei Chen, Qun Zhang, Chenliang Den. Human-specific gene CHRFAM7A mediates M2 macrophage polarization via the Notch pathway to ameliorate hypertrophic scar formation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 131. 2021-02-17. PMID:32890966. |
it is generally believed that anti-inflammatory scar therapies are the best strategies for treatment because excessive inflammation is observed in hypertrophic scar tissue. |
2021-02-17 |
2023-08-13 |
mouse |
| Tianya Li, Wei Chen, Qun Zhang, Chenliang Den. Human-specific gene CHRFAM7A mediates M2 macrophage polarization via the Notch pathway to ameliorate hypertrophic scar formation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 131. 2021-02-17. PMID:32890966. |
the chrfam7a gene was overexpressed in a hypertrophic scar mouse model using a lentivirus system. |
2021-02-17 |
2023-08-13 |
mouse |
| Tianya Li, Wei Chen, Qun Zhang, Chenliang Den. Human-specific gene CHRFAM7A mediates M2 macrophage polarization via the Notch pathway to ameliorate hypertrophic scar formation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 131. 2021-02-17. PMID:32890966. |
in the chrfam7a-transfected hypertrophic scar mouse group, the number of m1 macrophages increased dramatically in the initial period. |
2021-02-17 |
2023-08-13 |
mouse |
| Tianya Li, Wei Chen, Qun Zhang, Chenliang Den. Human-specific gene CHRFAM7A mediates M2 macrophage polarization via the Notch pathway to ameliorate hypertrophic scar formation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 131. 2021-02-17. PMID:32890966. |
our results demonstrate that chrfam7a can effectively ameliorate hypertrophic scar formation via regulation of macrophage phenotypic transition. |
2021-02-17 |
2023-08-13 |
mouse |
| Lung Chow, Kit-Lun Yick, Yue Sun, Matthew S H Leung, Mei-Ying Kwan, Sun-Pui Ng, Annie Yu, Joanne Yip, Ying-Fan Cha. A Novel Bespoke Hypertrophic Scar Treatment: Actualizing Hybrid Pressure and Silicone Therapies with 3D Printing and Scanning. International journal of bioprinting. vol 7. issue 1. 2021-02-16. PMID:33585716. |
a novel bespoke hypertrophic scar treatment: actualizing hybrid pressure and silicone therapies with 3d printing and scanning. |
2021-02-16 |
2023-08-13 |
Not clear |
| Xianglong Meng, Xinxin Gao, Xinxin Chen, Jiaao Y. Umbilical cord-derived mesenchymal stem cells exert anti-fibrotic action on hypertrophic scar-derived fibroblasts in co-culture by inhibiting the activation of the TGF β1/Smad3 pathway. Experimental and therapeutic medicine. vol 21. issue 3. 2021-02-13. PMID:33574910. |
a hypertrophic scar (hs) is a severe fibrotic skin disease that causes disfigurement and deformity. |
2021-02-13 |
2023-08-13 |
Not clear |
| Xianglong Meng, Xinxin Gao, Xinxin Chen, Jiaao Y. Umbilical cord-derived mesenchymal stem cells exert anti-fibrotic action on hypertrophic scar-derived fibroblasts in co-culture by inhibiting the activation of the TGF β1/Smad3 pathway. Experimental and therapeutic medicine. vol 21. issue 3. 2021-02-13. PMID:33574910. |
the present study aimed to evaluate the effects of umbilical cord-derived mesenchymal stem cells (ucmscs) on hypertrophic scar fibroblasts (hsfs), one of the main effector cells for hs formation, in a co-culture system and to investigate the potential underlying molecular mechanism. |
2021-02-13 |
2023-08-13 |
Not clear |
| Elvira Immacolata Parrotta, Valeria Lucchino, Luana Scaramuzzino, Stefania Scalise, Giovanni Cud. Modeling Cardiac Disease Mechanisms Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Progress, Promises and Challenges. International journal of molecular sciences. vol 21. issue 12. 2021-02-12. PMID:32575374. |
the hallmarks of cardiac diseases include heart dysfunction and cardiomyocyte death, inflammation, fibrosis, scar tissue, hyperplasia, hypertrophy, and abnormal ventricular remodeling. |
2021-02-12 |
2023-08-13 |
human |
| Beibei Yang, Yating Dong, Yifeng Shen, Ailin Hou, Guilan Quan, Xin Pan, Chuanbin W. Bilayer dissolving microneedle array containing 5-fluorouracil and triamcinolone with biphasic release profile for hypertrophic scar therapy. Bioactive materials. vol 6. issue 8. 2021-02-10. PMID:33553824. |
bilayer dissolving microneedle array containing 5-fluorouracil and triamcinolone with biphasic release profile for hypertrophic scar therapy. |
2021-02-10 |
2023-08-13 |
Not clear |
| Beibei Yang, Yating Dong, Yifeng Shen, Ailin Hou, Guilan Quan, Xin Pan, Chuanbin W. Bilayer dissolving microneedle array containing 5-fluorouracil and triamcinolone with biphasic release profile for hypertrophic scar therapy. Bioactive materials. vol 6. issue 8. 2021-02-10. PMID:33553824. |
hypertrophic scar (hs) is an undesirable skin abnormality following deep burns or operations. |
2021-02-10 |
2023-08-13 |
Not clear |
| Huan Deng, Cecilia W P Li-Tsang, Jingbo L. Measuring vascularity of hypertrophic scars by dermoscopy: Construct validity and predictive ability of scar thickness change. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). vol 26. issue 3. 2021-02-08. PMID:31916320. |
measuring vascularity of hypertrophic scars by dermoscopy: construct validity and predictive ability of scar thickness change. |
2021-02-08 |
2023-08-13 |
Not clear |
| Huan Deng, Cecilia W P Li-Tsang, Jingbo L. Measuring vascularity of hypertrophic scars by dermoscopy: Construct validity and predictive ability of scar thickness change. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). vol 26. issue 3. 2021-02-08. PMID:31916320. |
vascularity of hypertrophic scar is a key indicator of scar maturation and a vital parameter of evaluating effects of scar management interventions. |
2021-02-08 |
2023-08-13 |
Not clear |
| Huan Deng, Cecilia W P Li-Tsang, Jingbo L. Measuring vascularity of hypertrophic scars by dermoscopy: Construct validity and predictive ability of scar thickness change. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). vol 26. issue 3. 2021-02-08. PMID:31916320. |
this study aims to explore the construct validity of dermoscopy for measuring vascularity of hypertrophic scar and its predictive ability of scar thickness change. |
2021-02-08 |
2023-08-13 |
Not clear |
| Z Huang, Y Chen, P Wang, D W Zheng, Y L Zong, G Z Ly. [A prospective randomized controlled clinical study on the treatment of hypertrophic scar after burn by fractional carbon dioxide laser combined with autologous fat injection]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 37. issue 1. 2021-01-28. PMID:33499569. |
[a prospective randomized controlled clinical study on the treatment of hypertrophic scar after burn by fractional carbon dioxide laser combined with autologous fat injection]. |
2021-01-28 |
2023-08-13 |
Not clear |
| L Yang, N Li, J Cheng, J T Han, D H H. [A prospective randomized controlled clinical study on the optimal treatment interval of pulsed dye laser in treating hypertrophic scar after burn]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 37. issue 1. 2021-01-28. PMID:33499570. |
[a prospective randomized controlled clinical study on the optimal treatment interval of pulsed dye laser in treating hypertrophic scar after burn]. |
2021-01-28 |
2023-08-13 |
Not clear |
| Margit Juhasz, Nathan Fackler, Christine Pham, Natasha Atanaskova Mesinkovsk. Combination Therapy Using Radiofrequency Microneedling and Corticosteroids for Hypertrophic Scars: A Case Report. The Journal of clinical and aesthetic dermatology. vol 13. issue 12. 2021-01-26. PMID:33488915. |
dysregulated scar formation can cause hypertrophic scarring, a difficult entity to treat. |
2021-01-26 |
2023-08-13 |
Not clear |
| B Y Guo, D W Jiang, Q Hui, J Chai, K Ta. [Expression and effect of microRNA-205 in hypertrophic scar]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 37. issue 2. 2021-01-26. PMID:33498101. |
[expression and effect of microrna-205 in hypertrophic scar]. |
2021-01-26 |
2023-08-13 |
Not clear |