| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yue-Hua Li, Jiaomei Yang, Zhao Zheng, Da-Hai Hu, Zhi-Dong Wan. Botulinum toxin type A attenuates hypertrophic scar formation via the inhibition of TGF-β1/Smad and ERK pathways. Journal of cosmetic dermatology. vol 20. issue 5. 2021-05-14. PMID:33185943. |
previous studies have showed that botulinum toxin type a (bta) has effects on the prevention and treatment of hypertrophic scar, but little is known about the specific mechanisms. |
2021-05-14 |
2023-08-13 |
Not clear |
| Yanpeng Zhou, Xun Shi, Shengfei Li, Quan Gan, Zhengjun Cu. microRNA-181a promotes the proliferation of hypertrophic scar fibroblasts and inhibits their apoptosis via targeting phosphatase and tensin homolog. Annals of palliative medicine. vol 10. issue 4. 2021-05-14. PMID:33966404. |
microrna-181a promotes the proliferation of hypertrophic scar fibroblasts and inhibits their apoptosis via targeting phosphatase and tensin homolog. |
2021-05-14 |
2023-08-13 |
human |
| Yanpeng Zhou, Xun Shi, Shengfei Li, Quan Gan, Zhengjun Cu. microRNA-181a promotes the proliferation of hypertrophic scar fibroblasts and inhibits their apoptosis via targeting phosphatase and tensin homolog. Annals of palliative medicine. vol 10. issue 4. 2021-05-14. PMID:33966404. |
this study aimed to compare the expression of microrna (mir)-181a and phosphatase and tensin homolog (pten) in hypertrophic scar tissue and cells and to explore the effects of mir-181a and pten on the proliferation and apoptosis of the human scar fibroblast cell line hsfb. |
2021-05-14 |
2023-08-13 |
human |
| Chen Fan, Samir El Andaloussi, Taavi Lehto, Kiat Whye Kong, Yiqi Seo. Smad‑binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts. Molecular medicine reports. vol 22. issue 6. 2021-05-13. PMID:33173952. |
smad‑binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts. |
2021-05-13 |
2023-08-13 |
human |
| Chen Fan, Samir El Andaloussi, Taavi Lehto, Kiat Whye Kong, Yiqi Seo. Smad‑binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts. Molecular medicine reports. vol 22. issue 6. 2021-05-13. PMID:33173952. |
however, excessive collagen deposition by fibroblasts has been demonstrated to result in hypertrophic scar formation, and collagen synthesis in dermal fibroblasts is regulated by the transforming growth factor‑β1/smad signaling pathway. |
2021-05-13 |
2023-08-13 |
human |
| Chen Fan, Samir El Andaloussi, Taavi Lehto, Kiat Whye Kong, Yiqi Seo. Smad‑binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts. Molecular medicine reports. vol 22. issue 6. 2021-05-13. PMID:33173952. |
data generated from the present study provide evidence supporting the use of the smad decoy as a potential hypertrophic scar treatment. |
2021-05-13 |
2023-08-13 |
human |
| Rei Ogawa, Teruyuki Dohi, Mamiko Tosa, Masayo Aoki, Satoshi Akaish. The Latest Strategy for Keloid and Hypertrophic Scar Prevention and Treatment: The Nippon Medical School (NMS) Protocol. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. vol 88. issue 1. 2021-05-10. PMID:32741903. |
the latest strategy for keloid and hypertrophic scar prevention and treatment: the nippon medical school (nms) protocol. |
2021-05-10 |
2023-08-13 |
Not clear |
| Dan Zhang, Bo Li, Muxin Zha. Therapeutic Strategies by Regulating Interleukin Family to Suppress Inflammation in Hypertrophic Scar and Keloid. Frontiers in pharmacology. vol 12. 2021-05-08. PMID:33959031. |
therapeutic strategies by regulating interleukin family to suppress inflammation in hypertrophic scar and keloid. |
2021-05-08 |
2023-08-13 |
Not clear |
| Dan Zhang, Bo Li, Muxin Zha. Therapeutic Strategies by Regulating Interleukin Family to Suppress Inflammation in Hypertrophic Scar and Keloid. Frontiers in pharmacology. vol 12. 2021-05-08. PMID:33959031. |
hypertrophic scar (hs) and keloid are fibroproliferative disorders (fpds) of the skin due to aberrant wound healing, which cause disfigured appearance, discomfort, dysfunction, psychological stress, and patient frustration. |
2021-05-08 |
2023-08-13 |
Not clear |
| Qiang Sun, Er-Te Yu, You Zhou, Shuang Tong, Xu Sun, Ke-Zhu Li, Meng-Zhu Lv, Shu Gu. The Effects of Timing of Postoperative Radiotherapy on Hypertrophic Scar in a Rabbit Model. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-05. PMID:32678806. |
the effects of timing of postoperative radiotherapy on hypertrophic scar in a rabbit model. |
2021-05-05 |
2023-08-13 |
rabbit |
| Qiang Sun, Er-Te Yu, You Zhou, Shuang Tong, Xu Sun, Ke-Zhu Li, Meng-Zhu Lv, Shu Gu. The Effects of Timing of Postoperative Radiotherapy on Hypertrophic Scar in a Rabbit Model. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-05. PMID:32678806. |
background hypertrophic scar is associated with excessive proliferation of fibroblasts, the accumulation of collagen fibers, and angiogenesis associated with chronic inflammation. |
2021-05-05 |
2023-08-13 |
rabbit |
| Qiang Sun, Er-Te Yu, You Zhou, Shuang Tong, Xu Sun, Ke-Zhu Li, Meng-Zhu Lv, Shu Gu. The Effects of Timing of Postoperative Radiotherapy on Hypertrophic Scar in a Rabbit Model. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-05. PMID:32678806. |
this study aimed to investigate the association between the timing of postoperative radiotherapy and the effects on hypertrophic scar in a rabbit model. |
2021-05-05 |
2023-08-13 |
rabbit |
| Qiang Sun, Er-Te Yu, You Zhou, Shuang Tong, Xu Sun, Ke-Zhu Li, Meng-Zhu Lv, Shu Gu. The Effects of Timing of Postoperative Radiotherapy on Hypertrophic Scar in a Rabbit Model. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-05. PMID:32678806. |
material and methods forty new zealand white rabbits, 8-12 months old, weighing 1.8-2.3 kg were used in the model of hypertrophic scar and underwent surgical resection with or without postoperative radiotherapy. |
2021-05-05 |
2023-08-13 |
rabbit |
| Qiang Sun, Er-Te Yu, You Zhou, Shuang Tong, Xu Sun, Ke-Zhu Li, Meng-Zhu Lv, Shu Gu. The Effects of Timing of Postoperative Radiotherapy on Hypertrophic Scar in a Rabbit Model. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-05. PMID:32678806. |
the rabbit ear skin was observed after treatment, and the hypertrophic scar index (hi), fibroblast numerical area density (na), and collagen fiber area density (aa) were determined. |
2021-05-05 |
2023-08-13 |
rabbit |
| Qiang Sun, Er-Te Yu, You Zhou, Shuang Tong, Xu Sun, Ke-Zhu Li, Meng-Zhu Lv, Shu Gu. The Effects of Timing of Postoperative Radiotherapy on Hypertrophic Scar in a Rabbit Model. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-05. PMID:32678806. |
conclusions in a rabbit model of hypertrophic scar, surgical resection combined with radiotherapy resulted in an optimal effect within 24 hours after surgery. |
2021-05-05 |
2023-08-13 |
rabbit |
| Xianpeng Ma, Lili Li. Knockdown of FAM225B inhibits the progression of the hypertrophic scar following glaucoma surgery by inhibiting autophagy. Molecular medicine reports. vol 23. issue 3. 2021-05-04. PMID:33495826. |
knockdown of fam225b inhibits the progression of the hypertrophic scar following glaucoma surgery by inhibiting autophagy. |
2021-05-04 |
2023-08-13 |
Not clear |
| Xianpeng Ma, Lili Li. Knockdown of FAM225B inhibits the progression of the hypertrophic scar following glaucoma surgery by inhibiting autophagy. Molecular medicine reports. vol 23. issue 3. 2021-05-04. PMID:33495826. |
the formation of a hypertrophic scar (hs) may lead to failure of glaucoma surgery. |
2021-05-04 |
2023-08-13 |
Not clear |
| Jun Qi, Yangyang Wu, Haijian Zhang, Yifei Li. LncRNA NORAD regulates scar hypertrophy via miRNA-26a mediating the regulation of TGFβR1/2. Advances in clinical and experimental medicine : official organ Wroclaw Medical University. vol 30. issue 4. 2021-05-04. PMID:33857357. |
lncrna norad regulates scar hypertrophy via mirna-26a mediating the regulation of tgfβr1/2. |
2021-05-04 |
2023-08-13 |
Not clear |
| Jun Qi, Yangyang Wu, Haijian Zhang, Yifei Li. LncRNA NORAD regulates scar hypertrophy via miRNA-26a mediating the regulation of TGFβR1/2. Advances in clinical and experimental medicine : official organ Wroclaw Medical University. vol 30. issue 4. 2021-05-04. PMID:33857357. |
transforming growth factor-β (tgf-β) pathway presents dysregulation in pathological scarring and mediates hypertrophic scar (hs) formation. |
2021-05-04 |
2023-08-13 |
Not clear |
| Kun Pang, Bibo Li, Zhiming Tang, Wen Yang, Lin Hao, Zhenduo Shi, Jianjun Zhang, Longjun Cai, Rui Li, Ying Liu, Qian Lv, Jicun Ding, Conghui Ha. Resveratrol inhibits hypertrophic scars formation by activating autophagy via the miR-4654/Rheb axis. Molecular medicine reports. vol 22. issue 4. 2021-04-30. PMID:32945452. |
hypertrophic scars (hss) are a type of pathological scar which are induced by surgery, burn injuries or trauma during the healing process. |
2021-04-30 |
2023-08-13 |
Not clear |