| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ling Zhou, Zeming Liu, Sichao Chen, Jing Qiu, Qianqian Li, Shipei Wang, Wei Zhou, Danyang Chen, Guang Yang, Liang Gu. Transcription factor EB‑mediated autophagy promotes dermal fibroblast differentiation and collagen production by regulating endoplasmic reticulum stress and autophagy‑dependent secretion. International journal of molecular medicine. vol 47. issue 2. 2021-07-12. PMID:33416091. |
autophagy is reported to be involved in the formation of skin hypertrophic scar (hts). |
2021-07-12 |
2023-08-13 |
Not clear |
| Prashant Pawar, Sagar Vaishampayan, Dinesh H Shah, Ameya Pa. Retro-auricular endo assisted selective neck dissection (how I do it). Oral oncology. vol 110. 2021-07-09. PMID:32827834. |
however sometimes, the neck scar is hypertrophic and is highly unaesthetic and psychologically distressing to the patient. |
2021-07-09 |
2023-08-13 |
Not clear |
| Yan Li, Jian Zhang, Jihong Shi, Kaituo Liu, Xujie Wang, Yanhui Jia, Ting He, Kuo Shen, Yunchuan Wang, Jiaqi Liu, Wei Zhang, Hongtao Wang, Zhao Zheng, Dahai H. Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis. Stem cell research & therapy. vol 12. issue 1. 2021-07-08. PMID:33789737. |
exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by mir-192-5p/il-17ra/smad axis. |
2021-07-08 |
2023-08-13 |
human |
| Yan Li, Jian Zhang, Jihong Shi, Kaituo Liu, Xujie Wang, Yanhui Jia, Ting He, Kuo Shen, Yunchuan Wang, Jiaqi Liu, Wei Zhang, Hongtao Wang, Zhao Zheng, Dahai H. Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis. Stem cell research & therapy. vol 12. issue 1. 2021-07-08. PMID:33789737. |
hypertrophic scar (hs) is a fibro-proliferative disorder of dermis after burn or trauma and usually leads to esthetic disfiguration and functionary impairment for patients. |
2021-07-08 |
2023-08-13 |
human |
| Aishwari S Kumar, Kaladhar Kamalasana. Drug delivery to optimize angiogenesis imbalance in keloid: A review. Journal of controlled release : official journal of the Controlled Release Society. vol 329. 2021-07-05. PMID:33091533. |
where, any imbalance can lead to the formation of unwanted keloids, hypertrophic scar, or tumors. |
2021-07-05 |
2023-08-13 |
Not clear |
| Syrine Arif, Emilie Attiogbe, Véronique J Mouli. Granulation tissue myofibroblasts during normal and pathological skin healing: The interaction between their secretome and the microenvironment. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 29. issue 4. 2021-07-02. PMID:33887793. |
pathologically, granulation tissue can develop into a hypertrophic scar that histologically looks like granulation tissue, but which can remain for months or even years. |
2021-07-02 |
2023-08-13 |
Not clear |
| Mariana Campos Souza Menezes, Marcelo Buzelin, Cristiana Buzelin Nunes, Luiz Ronaldo Albert. Tacrolimus action pathways in an ointment base for hypertrophic scar prevention in a rabbit ear model. Anais brasileiros de dermatologia. vol 96. issue 4. 2021-07-01. PMID:34006401. |
tacrolimus action pathways in an ointment base for hypertrophic scar prevention in a rabbit ear model. |
2021-07-01 |
2023-08-13 |
rabbit |
| Emre Sinan Güngör, Duygu Güzel, Ali Galip Zebitay, Gülşah İlhan, Fatma Ferda Veri. The efficacy of onion extract in the management of subsequent abdominal hypertrophic scar formation. Journal of wound care. vol 29. issue 10. 2021-06-29. PMID:33052789. |
the efficacy of onion extract in the management of subsequent abdominal hypertrophic scar formation. |
2021-06-29 |
2023-08-13 |
Not clear |
| Jialun Li, Jiecong Wang, Zhenxing Wang, Yun Xia, Muran Zhou, Aimei Zhong, Jiaming Su. Experimental models for cutaneous hypertrophic scar research. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 28. issue 1. 2021-06-28. PMID:31509318. |
experimental models for cutaneous hypertrophic scar research. |
2021-06-28 |
2023-08-13 |
human |
| Cheong Hoon Seo, Hui Song Cui, June-Bum Ki. Calpastatin-Mediated Inhibition of Calpain Ameliorates Skin Scar Formation after Burn Injury. International journal of molecular sciences. vol 22. issue 11. 2021-06-28. PMID:34071277. |
this study demonstrates the pathological role of calpain and the antifibrotic effect of calpastatin via calpain inhibition in post-burn hypertrophic scar formation. |
2021-06-28 |
2023-08-13 |
human |
| Q N Zhao, Y M Zhou, C Y Su. [Research advances on the effect of mechanical tension in post-traumatic hypertrophic scar formation]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 37. issue 6. 2021-06-28. PMID:34167285. |
[research advances on the effect of mechanical tension in post-traumatic hypertrophic scar formation]. |
2021-06-28 |
2023-08-13 |
Not clear |
| Q N Zhao, Y M Zhou, C Y Su. [Research advances on the effect of mechanical tension in post-traumatic hypertrophic scar formation]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 37. issue 6. 2021-06-28. PMID:34167285. |
at present, scholars have confirmed from basic research that mechanical tension promotes the proliferation of inflammatory cells, fibroblasts, and other cells, as well as angiogenesis and epithelialization through a variety of mechanical conduction pathways and plays an important role in the formation of hypertrophic scar. |
2021-06-28 |
2023-08-13 |
Not clear |
| Q N Zhao, Y M Zhou, C Y Su. [Research advances on the effect of mechanical tension in post-traumatic hypertrophic scar formation]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 37. issue 6. 2021-06-28. PMID:34167285. |
this article summarizes the mechanism of hypertrophic scar formation, and surgical methods and adjunct means of reducing mechanical tension in traumatic wounds, aiming to provide a reference for reducing formation of hypertrophic scar in clinics. |
2021-06-28 |
2023-08-13 |
Not clear |
| Jun Tang, Jianing Yang, Hua Hu, Ying Cen, Junjie Che. miR-211-5p inhibits the proliferation, migration, invasion, and induces apoptosis of human hypertrophic scar fibroblasts by regulating TGFβR2 expression. Annals of translational medicine. vol 9. issue 10. 2021-06-25. PMID:34164498. |
mir-211-5p inhibits the proliferation, migration, invasion, and induces apoptosis of human hypertrophic scar fibroblasts by regulating tgfβr2 expression. |
2021-06-25 |
2023-08-13 |
human |
| Ling Gao, Lu Wang, Yuhua Wei, Prasanna Krishnamurthy, Gregory P Walcott, Philippe Menasché, Jianyi Zhan. Exosomes secreted by hiPSC-derived cardiac cells improve recovery from myocardial infarction in swine. Science translational medicine. vol 12. issue 561. 2021-06-23. PMID:32938792. |
in vivo, measurements of left ventricular ejection fraction, wall stress, myocardial bioenergetics, cardiac hypertrophy, scar size, cell apoptosis, and angiogenesis in the infarcted region were better in the mi + cell, mi + fra, and mi + exo groups than in the mi group 4 weeks after infarction. |
2021-06-23 |
2023-08-13 |
mouse |
| Woraphong Manuskiatti, Arisa Kaewkes, Chadakan Yan, Janice Natasha Ng, Joshua Zev Glahn, Rungsima Wanitphakdeedech. Hypertrophic Scar Outcomes in Fractional Laser Monotherapy Versus Fractional Laser-Assisted Topical Corticosteroid Delivery: A Randomized Clinical Trial. Acta dermato-venereologica. vol 101. issue 3. 2021-06-23. PMID:33686446. |
hypertrophic scar outcomes in fractional laser monotherapy versus fractional laser-assisted topical corticosteroid delivery: a randomized clinical trial. |
2021-06-23 |
2023-08-13 |
human |
| Bin Hu, Jing Wang, Jiarui Chen, Limin Zhao, Xiaoyan L. The heterogeneity of fibroblasts in laryngotracheal stenosis and skin hypertrophic scar in pediatric patients. International journal of pediatric otorhinolaryngology. vol 145. 2021-06-23. PMID:33910042. |
the heterogeneity of fibroblasts in laryngotracheal stenosis and skin hypertrophic scar in pediatric patients. |
2021-06-23 |
2023-08-13 |
Not clear |
| Bin Hu, Jing Wang, Jiarui Chen, Limin Zhao, Xiaoyan L. The heterogeneity of fibroblasts in laryngotracheal stenosis and skin hypertrophic scar in pediatric patients. International journal of pediatric otorhinolaryngology. vol 145. 2021-06-23. PMID:33910042. |
to investigate the heterogeneity between the laryngotracheal stenosis and hypertrophic scar derived fibroblasts. |
2021-06-23 |
2023-08-13 |
Not clear |
| Yun Li, Zhencheng Yu, Danyang Zhao, Dong Ha. Corilagin alleviates hypertrophic scars via inhibiting the transforming growth factor (TGF)-β/Smad signal pathway. Life sciences. vol 277. 2021-06-22. PMID:33862115. |
exploring the effects of corilagin on hypertrophic scar (hs) and its underlying mechanisms. |
2021-06-22 |
2023-08-13 |
Not clear |
| Ernest A Azzopardi, Robert T Duncan, Mollie Kearns, Francesco Marangoni, Nader Ibrahim, Ernest A F Azzopardi, Dean Boyce, Matteo Tretti, Maxwell S C Mursio. Cutaneous laser surgery for secondary burn reconstruction: Cost benefit analysis. Burns : journal of the International Society for Burn Injuries. vol 46. issue 3. 2021-06-18. PMID:31955979. |
laser surgery has recently come of age as an optimal tool in the secondary reconstruction of burn injury, that is able to simultaneously address significant sheet scar tightness, hypertrophic, atrophic, and keloid complications, pruritus, microstomia, ectropion, skin graft honeycombing, and improve range of movement whilst reducing the risk of infection to <1%. |
2021-06-18 |
2023-08-13 |
Not clear |