| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xian-Min Li, Wen-Yuan Yu, Qi Chen, Hui-Ru Zhuang, Su-Yue Gao, Tian-Lan Zha. LncRNA TUG1 exhibits pro-fibrosis activity in hypertrophic scar through TAK1/YAP/TAZ pathway via miR-27b-3p. Molecular and cellular biochemistry. vol 476. issue 8. 2021-09-06. PMID:33791919. |
hypertrophic scar (hs) is a complicated fibrotic disease. |
2021-09-06 |
2023-08-13 |
Not clear |
| Kyle Sylakowski, Alan Well. ECM-regulation of autophagy: The yin and the yang of autophagy during wound healing. Matrix biology : journal of the International Society for Matrix Biology. vol 100-101. 2021-09-02. PMID:33421547. |
disruption of any of these steps results in the process being incomplete as an ulcer or over-exuberant as a hypertrophic scar. |
2021-09-02 |
2023-08-13 |
Not clear |
| Jun Wei, Zhiyong Wang, Chaoyi Zhong, Huarong Ding, Xiqiao Wang, Shuliang L. LncRNA MIR503HG promotes hypertrophic scar progression via miR-143-3p-mediated Smad3 expression. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 29. issue 5. 2021-09-02. PMID:33819360. |
lncrna mir503hg promotes hypertrophic scar progression via mir-143-3p-mediated smad3 expression. |
2021-09-02 |
2023-08-13 |
human |
| Jun Wei, Zhiyong Wang, Chaoyi Zhong, Huarong Ding, Xiqiao Wang, Shuliang L. LncRNA MIR503HG promotes hypertrophic scar progression via miR-143-3p-mediated Smad3 expression. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 29. issue 5. 2021-09-02. PMID:33819360. |
qrt-pcr was applied to examine the levels of mir503hg and mir-143-3p in hs tissues and human hypertrophic scar fibroblasts (hhsfs). |
2021-09-02 |
2023-08-13 |
human |
| Zhimin Jiang, Lichi Zhao, Feixiang He, Haixin Tan, Yongling Li, Yu Tang, Xiaoqun Duan, Yingying L. Palmatine-loaded electrospun poly(ε-caprolactone)/gelatin nanofibrous scaffolds accelerate wound healing and inhibit hypertrophic scar formation in a rabbit ear model. Journal of biomaterials applications. vol 35. issue 7. 2021-08-27. PMID:32799702. |
palmatine-loaded electrospun poly(ε-caprolactone)/gelatin nanofibrous scaffolds accelerate wound healing and inhibit hypertrophic scar formation in a rabbit ear model. |
2021-08-27 |
2023-08-13 |
rabbit |
| Zhimin Jiang, Lichi Zhao, Feixiang He, Haixin Tan, Yongling Li, Yu Tang, Xiaoqun Duan, Yingying L. Palmatine-loaded electrospun poly(ε-caprolactone)/gelatin nanofibrous scaffolds accelerate wound healing and inhibit hypertrophic scar formation in a rabbit ear model. Journal of biomaterials applications. vol 35. issue 7. 2021-08-27. PMID:32799702. |
hypertrophic scar (hs) has been considered as a great concern for patients and a challenging problem for clinicians as it can cause functional debility, cosmetic disfigurement and psychological trauma. |
2021-08-27 |
2023-08-13 |
rabbit |
| Shi Chen, Xuefeng Wang, Liwei Huang, Yucheng Chen, Qing Zhan. Performance of 12-lead electrocardiogram Selvester QRS scoring criteria to diagnose myocardial scar in patients with hypertrophic cardiomyopathy. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc. vol 25. issue 5. 2021-08-24. PMID:32378804. |
performance of 12-lead electrocardiogram selvester qrs scoring criteria to diagnose myocardial scar in patients with hypertrophic cardiomyopathy. |
2021-08-24 |
2023-08-13 |
Not clear |
| Shi Chen, Xuefeng Wang, Liwei Huang, Yucheng Chen, Qing Zhan. Performance of 12-lead electrocardiogram Selvester QRS scoring criteria to diagnose myocardial scar in patients with hypertrophic cardiomyopathy. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc. vol 25. issue 5. 2021-08-24. PMID:32378804. |
the selvester qrs score can identify the presence and extent of myocardial scar in ischemic and nonischemic cardiomyopathy, but its performance in patients with hypertrophic cardiomyopathy (hcm) has not been assessed. |
2021-08-24 |
2023-08-13 |
Not clear |
| Ichiro Kurokawa, Alison M Layton, Rei Ogaw. Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis. Dermatology and therapy. vol 11. issue 4. 2021-08-20. PMID:34115308. |
transforming growth factor-β (tgfβ), il-6, matrix metalloproteinase (mmp), igf-1, and b cells are found in keloid or hypertrophic scar tissues. |
2021-08-20 |
2023-08-13 |
Not clear |
| Samar A M Salem, Sharief M Abdel Hameed, Azza E Mostaf. Intense pulsed light versus cryotherapy in the treatment of hypertrophic scars: A clinical and histopathological study. Journal of cosmetic dermatology. vol 20. issue 9. 2021-08-19. PMID:33533134. |
different therapeutic modalities have been tried for hypertrophic scar treatment. |
2021-08-19 |
2023-08-13 |
Not clear |
| Ling Wang, Xiao-Shan Zhang, Chang-Lin Zhan. [Research progress on Pheretima and earthworms with related origin]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 13. 2021-08-17. PMID:34396748. |
according to recent studies,pheretima has anti-pulmonary and anti-renal interstitial fibrosis,respiratory syncytial virus-inhibiting,human hypertrophic scar fibroblast proliferation-suppressing,and mouse embryonic fibroblast proliferation-promoting effects. |
2021-08-17 |
2023-08-13 |
mouse |
| Lingfeng Pan, Haiyan Qin, Caihong Li, Liehao Yang, Mingxi Li, Jiao Kong, Guang Zhang, Lianbo Zhan. Safety and efficacy of botulinum toxin type A in preventing and treating scars in animal models: A systematic review and meta-analysis. International wound journal. 2021-08-17. PMID:34402205. |
this study shows that btxa is safe and effective in preventing and treating scar hypertrophy in animal models, but excessive doses of btxa and btxa to treat large areas should be avoided. |
2021-08-17 |
2023-08-13 |
Not clear |
| Shuchen Gu, Xin Huang, Xiangwen Xu, Yunhan Liu, Yimin Khoong, Zewei Zhang, Haizhou Li, Yashan Gao, Tao Za. Inhibition of CUB and sushi multiple domains 1 (CSMD1) expression by miRNA-190a-3p enhances hypertrophic scar-derived fibroblast migration in vitro. BMC genomics. vol 22. issue 1. 2021-08-16. PMID:34384362. |
hypertrophic scar (hts) is a fibroproliferative skin disorder characterized by excessive cell proliferation, migration, and extracellular matrix (ecm) deposition. |
2021-08-16 |
2023-08-13 |
Not clear |
| Shuchen Gu, Xin Huang, Xiangwen Xu, Yunhan Liu, Yimin Khoong, Zewei Zhang, Haizhou Li, Yashan Gao, Tao Za. Inhibition of CUB and sushi multiple domains 1 (CSMD1) expression by miRNA-190a-3p enhances hypertrophic scar-derived fibroblast migration in vitro. BMC genomics. vol 22. issue 1. 2021-08-16. PMID:34384362. |
the cub and sushi multiple domains 1 (csmd1) has previously been identified as the key regulatory gene of hypertrophic scar by a large sample gwas study. |
2021-08-16 |
2023-08-13 |
Not clear |
| Kristine M Chaudet, Amrita Goyal, Katy R Veprauskas, Rosalynn M Nazaria. Wnt Signaling Pathway Proteins in Scar, Hypertrophic Scar, and Keloid: Evidence for a Continuum? The American Journal of dermatopathology. vol 42. issue 11. 2021-08-13. PMID:32310858. |
wnt signaling pathway proteins in scar, hypertrophic scar, and keloid: evidence for a continuum? |
2021-08-13 |
2023-08-13 |
Not clear |
| Fang Xie, Li Teng, Jiajie Xu, Jianjian Lu, Chao Zhang, Liya Yang, Xiaoyang Ma, Minghao Zha. Interleukin-10 modified bone marrow mesenchymal stem cells prevent hypertrophic scar formation by inhibiting inflammation. Die Pharmazie. vol 75. issue 11. 2021-08-13. PMID:33239131. |
interleukin-10 modified bone marrow mesenchymal stem cells prevent hypertrophic scar formation by inhibiting inflammation. |
2021-08-13 |
2023-08-13 |
rabbit |
| Fang Xie, Li Teng, Jiajie Xu, Jianjian Lu, Chao Zhang, Liya Yang, Xiaoyang Ma, Minghao Zha. Interleukin-10 modified bone marrow mesenchymal stem cells prevent hypertrophic scar formation by inhibiting inflammation. Die Pharmazie. vol 75. issue 11. 2021-08-13. PMID:33239131. |
this study was performed to examine the effect of interleukin-10 (il-10) modified bone marrow mesenchymal stem cells (bmscs) on hypertrophic scar formation on the rabbit ear hypertrophic scar model. |
2021-08-13 |
2023-08-13 |
rabbit |
| Fang Xie, Li Teng, Jiajie Xu, Jianjian Lu, Chao Zhang, Liya Yang, Xiaoyang Ma, Minghao Zha. Interleukin-10 modified bone marrow mesenchymal stem cells prevent hypertrophic scar formation by inhibiting inflammation. Die Pharmazie. vol 75. issue 11. 2021-08-13. PMID:33239131. |
we treated the rabbit ear hypertrophic scar with bmscs and il-10-bmscs, then evaluated the area and measured the height of the hypertrophic scar, and detected expression using real-time pcr and western blot. |
2021-08-13 |
2023-08-13 |
rabbit |
| Fang Xie, Li Teng, Jiajie Xu, Jianjian Lu, Chao Zhang, Liya Yang, Xiaoyang Ma, Minghao Zha. Interleukin-10 modified bone marrow mesenchymal stem cells prevent hypertrophic scar formation by inhibiting inflammation. Die Pharmazie. vol 75. issue 11. 2021-08-13. PMID:33239131. |
after treating with a local injection of bmscs or il-10-bmscs in the rabbit ear hypertrophic scar, we found that the time of wound healing, the area and height of scar were all significantly reduced in the il-10-bmscs group when compared to those in the bmscs group. |
2021-08-13 |
2023-08-13 |
rabbit |
| Fang Xie, Li Teng, Jiajie Xu, Jianjian Lu, Chao Zhang, Liya Yang, Xiaoyang Ma, Minghao Zha. Interleukin-10 modified bone marrow mesenchymal stem cells prevent hypertrophic scar formation by inhibiting inflammation. Die Pharmazie. vol 75. issue 11. 2021-08-13. PMID:33239131. |
il-10 modified bmscs prevented hypertrophic scar formation in the rabbit ear hypertrophic scar model, and the results suggest this could be due to the inhibition of inflammation by il-10 modified bmscs through the jnk / nf-κb pathway. |
2021-08-13 |
2023-08-13 |
rabbit |