| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuan. MicroRNA-18a-5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression. Experimental and therapeutic medicine. vol 22. issue 5. 2021-10-12. PMID:34630672. |
the aim of the present study was to investigate the expression and role of microrna-18a-5p (mir-18a-5p) during the formation of hypertrophic scar (hs), and to further explore the molecular mechanisms involved. |
2021-10-12 |
2023-08-13 |
human |
| Qiang Dai, Qian Yu, Ran Xiao, Lei Ca. Early Intervention with Autologous Fat Grafting to Reduce Hypertrophic Scar Formation: A Prelimilary Study. Aesthetic plastic surgery. vol 45. issue 5. 2021-10-11. PMID:33885941. |
early intervention with autologous fat grafting to reduce hypertrophic scar formation: a prelimilary study. |
2021-10-11 |
2023-08-13 |
Not clear |
| Qiang Dai, Qian Yu, Ran Xiao, Lei Ca. Early Intervention with Autologous Fat Grafting to Reduce Hypertrophic Scar Formation: A Prelimilary Study. Aesthetic plastic surgery. vol 45. issue 5. 2021-10-11. PMID:33885941. |
once an early-stage immature scar develops into a hypertrophic scar, it is difficult to achieve satisfactory improvement with existing treatments. |
2021-10-11 |
2023-08-13 |
Not clear |
| Qiang Dai, Qian Yu, Ran Xiao, Lei Ca. Early Intervention with Autologous Fat Grafting to Reduce Hypertrophic Scar Formation: A Prelimilary Study. Aesthetic plastic surgery. vol 45. issue 5. 2021-10-11. PMID:33885941. |
therefore, the prevention of hypertrophic scar formation should be given priority. |
2021-10-11 |
2023-08-13 |
Not clear |
| Wenxuan Zu, Banghong Jiang, Hongwei Li. Establishment of a long-term hypertrophic scar model by injection of anhydrous alcohol: A rabbit model. International journal of experimental pathology. vol 102. issue 2. 2021-10-08. PMID:33710702. |
establishment of a long-term hypertrophic scar model by injection of anhydrous alcohol: a rabbit model. |
2021-10-08 |
2023-08-13 |
human |
| Wenxuan Zu, Banghong Jiang, Hongwei Li. Establishment of a long-term hypertrophic scar model by injection of anhydrous alcohol: A rabbit model. International journal of experimental pathology. vol 102. issue 2. 2021-10-08. PMID:33710702. |
the processes of hypertrophic scar formation are extremely complex, and current animal models have limitations in terms of the complete characterization of lesions. |
2021-10-08 |
2023-08-13 |
human |
| Wenxuan Zu, Banghong Jiang, Hongwei Li. Establishment of a long-term hypertrophic scar model by injection of anhydrous alcohol: A rabbit model. International journal of experimental pathology. vol 102. issue 2. 2021-10-08. PMID:33710702. |
the dermal scar was generated by treating with 2 ml/kg anhydrous alcohol and displayed histopathologic features that characterize human hypertrophic scarring, including a parallel collagen fibre orientation, dermal and epidermal thickening, broad collagen deposition and the loss of dermal adnexal structures. |
2021-10-08 |
2023-08-13 |
human |
| Karina Teja Putri, Theddeus Octavianus Hari Prasetyon. A critical review on the potential role of adipose-derived stem cells for future treatment of hypertrophic scars. Journal of cosmetic dermatology. 2021-10-07. PMID:34619011. |
adipose-derived stem cells (ascs) have recently gained researchers' interest as a solution to various diseases and conditions, including hypertrophic scar. |
2021-10-07 |
2023-08-13 |
human |
| Karina Teja Putri, Theddeus Octavianus Hari Prasetyon. A critical review on the potential role of adipose-derived stem cells for future treatment of hypertrophic scars. Journal of cosmetic dermatology. 2021-10-07. PMID:34619011. |
this literature review aims to elucidate ascs as a potential solution to alleviate hypertrophic scar in human subjects. |
2021-10-07 |
2023-08-13 |
human |
| Bernadette Nedelec, Leo LaSalle, Ana de Oliveira, José A Corre. Within-Patient, Single-Blinded, Randomized Controlled Clinical Trial to Evaluate the Efficacy of Triamcinolone Acetonide Injections for the Treatment of Hypertrophic Scar in Adult Burn Survivors. Journal of burn care & research : official publication of the American Burn Association. vol 41. issue 4. 2021-10-05. PMID:32303737. |
within-patient, single-blinded, randomized controlled clinical trial to evaluate the efficacy of triamcinolone acetonide injections for the treatment of hypertrophic scar in adult burn survivors. |
2021-10-05 |
2023-08-13 |
human |
| Bernadette Nedelec, Leo LaSalle, Ana de Oliveira, José A Corre. Within-Patient, Single-Blinded, Randomized Controlled Clinical Trial to Evaluate the Efficacy of Triamcinolone Acetonide Injections for the Treatment of Hypertrophic Scar in Adult Burn Survivors. Journal of burn care & research : official publication of the American Burn Association. vol 41. issue 4. 2021-10-05. PMID:32303737. |
intralesional corticosteroid (triamcinolone acetonide [tac]) injections have become one of the cornerstone treatments of hypertrophic scar (hsc). |
2021-10-05 |
2023-08-13 |
human |
| Song Tian, Yongjun Zheng, Shichu Xiao, Pengfei Luo, Rongju Sun, Jun Liu, Zhaofan Xi. Ivermectin inhibits cell proliferation and the expression levels of type I collagen, α‑SMA and CCN2 in hypertrophic scar fibroblasts. Molecular medicine reports. vol 24. issue 1. 2021-10-05. PMID:33955514. |
ivermectin inhibits cell proliferation and the expression levels of type i collagen, α‑sma and ccn2 in hypertrophic scar fibroblasts. |
2021-10-05 |
2023-08-13 |
Not clear |
| Zhi Zhang, Changling Liu, Bin Chen, Wenbin Tang, Zhihe Liu, Wenjuan Cao, Xiaojian L. Smad7 down-regulation via ubiquitin degradation mediated by Smurf2 in fibroblasts of hypertrophic scars in burned patients. Burns : journal of the International Society for Burn Injuries. vol 47. issue 6. 2021-10-04. PMID:33436154. |
we thus made a hypothesis that smad7 could not inhibit tgf-β1 because smurf2 ubiquitin degradation was increased in hypertrophic scar fibroblasts. |
2021-10-04 |
2023-08-13 |
Not clear |
| Zhi Zhang, Changling Liu, Bin Chen, Wenbin Tang, Zhihe Liu, Wenjuan Cao, Xiaojian L. Smad7 down-regulation via ubiquitin degradation mediated by Smurf2 in fibroblasts of hypertrophic scars in burned patients. Burns : journal of the International Society for Burn Injuries. vol 47. issue 6. 2021-10-04. PMID:33436154. |
furthermore, it was found that tgf-β1 stimulation increased smad7 protein expression after silencing smurf2 gene in hypertrophic scar fibroblasts, and enhanced smad7 degradation was prevented in hypertrophic scar fibroblasts after smurf2 was silenced. |
2021-10-04 |
2023-08-13 |
Not clear |
| Christine Bojanic, Kendrick To, Adam Hatoum, Jessie Shea, K T Matthew Seah, Wasim Khan, Charles M Malat. Mesenchymal stem cell therapy in hypertrophic and keloid scars. Cell and tissue research. vol 383. issue 3. 2021-10-01. PMID:33386995. |
when a scar does not resolve, uncontrolled chronic inflammation can persist and elicits excessive scarring that leads to a range of abnormal phenotypes such as hypertrophic and keloid scars. |
2021-10-01 |
2023-08-13 |
human |
| Xiaoyu Ning, Christian Wiraja, Wan Ting Sharon Chew, Chen Fan, Chenjie X. Transdermal delivery of Chinese herbal medicine extract using dissolvable microneedles for hypertrophic scar treatment. Acta pharmaceutica Sinica. B. vol 11. issue 9. 2021-10-01. PMID:34589406. |
transdermal delivery of chinese herbal medicine extract using dissolvable microneedles for hypertrophic scar treatment. |
2021-10-01 |
2023-08-13 |
Not clear |
| Renpeng Zhou, Chuandong Wang, Dongze Lv, Yangbai Sun, Yimin Lian. TNF-α inhibits fibrosis and migration of fibroblasts in hypertrophic scar by miR-141-3p. Acta biochimica et biophysica Sinica. vol 53. issue 8. 2021-09-30. PMID:34143861. |
tnf-α inhibits fibrosis and migration of fibroblasts in hypertrophic scar by mir-141-3p. |
2021-09-30 |
2023-08-13 |
Not clear |
| Yogesh M Bhingaradia, Shailika J Gondaliy. Utilization of Nonabsorbable (Polyamide Black) Buried Subcutaneous Suture Material in Closure of Elliptical Excision in Various Indications for Better Aesthetic Outcome. Journal of cutaneous and aesthetic surgery. vol 14. issue 2. 2021-09-29. PMID:34566365. |
by using a modified vancouver scar scale, which includes an assessment of pliability, the height of scar, vascularity, and pigmentation, all postoperative scars were classified into five categories: excellent, good, moderate, hypertrophic scar, or keloid. |
2021-09-29 |
2023-08-13 |
Not clear |
| Yogesh M Bhingaradia, Shailika J Gondaliy. Utilization of Nonabsorbable (Polyamide Black) Buried Subcutaneous Suture Material in Closure of Elliptical Excision in Various Indications for Better Aesthetic Outcome. Journal of cutaneous and aesthetic surgery. vol 14. issue 2. 2021-09-29. PMID:34566365. |
of 155 patients, 72% of patients had excellent cosmetic outcome (0 score), 21.29% had good cosmetic outcome (1 score), and 2.58% had a moderate cosmetic outcome (2 score) without any hypertrophic scar or keloid by using a modified vancouver scar scale. |
2021-09-29 |
2023-08-13 |
Not clear |
| Sha Yang, Yujia J Luo, Cong Lu. Network Meta-Analysis of Different Clinical Commonly Used Drugs for the Treatment of Hypertrophic Scar and Keloid. Frontiers in medicine. vol 8. 2021-09-29. PMID:34568361. |
network meta-analysis of different clinical commonly used drugs for the treatment of hypertrophic scar and keloid. |
2021-09-29 |
2023-08-13 |
Not clear |