| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xingwang Deng, Fang Zhao, Dan Zhao, Qing Zhang, Yongzhao Zhu, Qian Chen, Lijuan Qiang, Nan Xie, Jiaxiang Ma, Xiaoliang Pan, Yinsheng Wu, Lifeng Guan, Yan Xi. Oxymatrine promotes hypertrophic scar repair through reduced human scar fibroblast viability, collagen and induced apoptosis via autophagy inhibition. International wound journal. 2021-11-08. PMID:34749441. |
in summary, oxymatrine promoted hypertrophic scar repair by decreasing hsf viability and collagen, and inducing apoptosis via autophagy inhibition. |
2021-11-08 |
2023-08-13 |
human |
| Xingwang Deng, Fang Zhao, Dan Zhao, Qing Zhang, Yongzhao Zhu, Qian Chen, Lijuan Qiang, Nan Xie, Jiaxiang Ma, Xiaoliang Pan, Yinsheng Wu, Lifeng Guan, Yan Xi. Oxymatrine promotes hypertrophic scar repair through reduced human scar fibroblast viability, collagen and induced apoptosis via autophagy inhibition. International wound journal. 2021-11-08. PMID:34749441. |
this study provides a new perspective on the mechanism of hypertrophic burn scar formation, as well as key scientific data for the application of the phytochemical oxymatrine as a new method for the prevention and treatment of hypertrophic scars. |
2021-11-08 |
2023-08-13 |
human |
| Norah Oles, Stephanie Preston, Angelo A Leto Barone, Aadil Khan, Devin Coo. Sensate total clitoris reconstruction via microneurovascular dorsal foot web space flap with pudendal nerve coaptation. Microsurgery. vol 41. issue 8. 2021-11-05. PMID:34655246. |
complications included donor site cellulitis with partial loss of the skin graft and formation of hypertrophic scar tissue. |
2021-11-05 |
2023-08-13 |
Not clear |
| Grace C Limandjaja, Frank B Niessen, Rik J Scheper, Susan Gibb. Hypertrophic scars and keloids: Overview of the evidence and practical guide for differentiating between these abnormal scars. Experimental dermatology. vol 30. issue 1. 2021-11-04. PMID:32479693. |
although hypertrophic scars and keloids both generate excessive scar tissue, keloids are characterized by their extensive growth beyond the borders of the original wound, which is not observed in hypertrophic scars. |
2021-11-04 |
2023-08-13 |
Not clear |
| Erik de Bakker, Mirthe A M van der Putten, Martijn W Heymans, Sander W Spiekstra, Taco Waaijman, Liselotte Butzelaar, Vera L Negenborn, Vivian K Beekman, Erman O Akpinar, Thomas Rustemeyer, Frank B Niessen, Susan Gibb. Prognostic tools for hypertrophic scar formation based on fundamental differences in systemic immunity. Experimental dermatology. vol 30. issue 1. 2021-11-04. PMID:32618380. |
prognostic tools for hypertrophic scar formation based on fundamental differences in systemic immunity. |
2021-11-04 |
2023-08-13 |
Not clear |
| Alexandra Laberge, Mays Merjaneh, Syrine Arif, Sébastien Larochelle, Véronique J Mouli. Shedding of proangiogenic microvesicles from hypertrophic scar myofibroblasts. Experimental dermatology. vol 30. issue 1. 2021-11-04. PMID:32813921. |
shedding of proangiogenic microvesicles from hypertrophic scar myofibroblasts. |
2021-11-04 |
2023-08-13 |
Not clear |
| Liam D Kirkpatrick, Jeffrey W Shupp, Robert D Smith, Abdulnaser Alkhalil, Lauren T Moffatt, Bonnie C Carne. Galectin-1 production is elevated in hypertrophic scar. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 29. issue 1. 2021-11-02. PMID:33073427. |
galectin-1 production is elevated in hypertrophic scar. |
2021-11-02 |
2023-08-13 |
human |
| Sijia Xu, Wenxin Dong, Yu Sh. LncRNA PICSAR binds to miR-485-5p and activates TGF-β1/Smad to promote abnormal proliferation of hypertrophic scar fibroblasts (HSFs) and excessive deposition of extracellular matrix (ECM). Medical molecular morphology. vol 54. issue 4. 2021-11-01. PMID:34255190. |
lncrna picsar binds to mir-485-5p and activates tgf-β1/smad to promote abnormal proliferation of hypertrophic scar fibroblasts (hsfs) and excessive deposition of extracellular matrix (ecm). |
2021-11-01 |
2023-08-13 |
Not clear |
| Sijia Xu, Wenxin Dong, Yu Sh. LncRNA PICSAR binds to miR-485-5p and activates TGF-β1/Smad to promote abnormal proliferation of hypertrophic scar fibroblasts (HSFs) and excessive deposition of extracellular matrix (ECM). Medical molecular morphology. vol 54. issue 4. 2021-11-01. PMID:34255190. |
the purpose of this study is to explore whether lncrna picsar binds to mir-485-5p and thereby activates tgf-β1/smad signaling pathway, influencing the abnormal proliferation of fibroblasts and excessive deposition of ecm in hypertrophic scar formation. |
2021-11-01 |
2023-08-13 |
Not clear |
| Sijia Xu, Wenxin Dong, Yu Sh. LncRNA PICSAR binds to miR-485-5p and activates TGF-β1/Smad to promote abnormal proliferation of hypertrophic scar fibroblasts (HSFs) and excessive deposition of extracellular matrix (ECM). Medical molecular morphology. vol 54. issue 4. 2021-11-01. PMID:34255190. |
interference with picsar inhibited the abnormal proliferation of hypertrophic scar fibroblasts (hsfs) and the excessive deposition of ecm. |
2021-11-01 |
2023-08-13 |
Not clear |
| Sijia Xu, Wenxin Dong, Yu Sh. LncRNA PICSAR binds to miR-485-5p and activates TGF-β1/Smad to promote abnormal proliferation of hypertrophic scar fibroblasts (HSFs) and excessive deposition of extracellular matrix (ECM). Medical molecular morphology. vol 54. issue 4. 2021-11-01. PMID:34255190. |
lncrna picsar binds to mir-485-5p and thereby activates tgf-β1/smad signaling pathway, promoting the abnormal proliferation of fibroblasts and excessive deposition of ecm in hypertrophic scar formation. |
2021-11-01 |
2023-08-13 |
Not clear |
| Jianglin Tan, Junyi Zhou, Ling Huang, Qingqing Fu, Ming Ao, Lili Yuan, Gaoxing Lu. Hypertrophic Scar Improvement by Early Intervention With Ablative Fractional Carbon Dioxide Laser Treatment. Lasers in surgery and medicine. vol 53. issue 4. 2021-10-28. PMID:32677058. |
hypertrophic scar improvement by early intervention with ablative fractional carbon dioxide laser treatment. |
2021-10-28 |
2023-08-13 |
Not clear |
| Keshvad Hedayatyanfard, Nazgol-Sadat Haddadi, Seyed Ali Ziai, Hossein Karim, Feizollah Niazi, Ulrike Muscha Steckelings, Behnam Habibi, Ali Modarressi, Ahmad-Reza Dehpou. The renin-angiotensin system in cutaneous hypertrophic scar and keloid formation. Experimental dermatology. vol 29. issue 9. 2021-10-28. PMID:32678966. |
the renin-angiotensin system in cutaneous hypertrophic scar and keloid formation. |
2021-10-28 |
2023-08-13 |
Not clear |
| Keshvad Hedayatyanfard, Nazgol-Sadat Haddadi, Seyed Ali Ziai, Hossein Karim, Feizollah Niazi, Ulrike Muscha Steckelings, Behnam Habibi, Ali Modarressi, Ahmad-Reza Dehpou. The renin-angiotensin system in cutaneous hypertrophic scar and keloid formation. Experimental dermatology. vol 29. issue 9. 2021-10-28. PMID:32678966. |
hypertrophic scar and keloid are two types of fibroproliferative conditions that result from excessive extracellular matrix production. |
2021-10-28 |
2023-08-13 |
Not clear |
| Mohammed J Manna, Muhannad Sami Jalil, Murtadha S Jabu. Topical Isoxsuprine in experimentally induced hypertrophic scar in rabbits. Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique. vol 28. issue 1. 2021-10-28. PMID:34553572. |
topical isoxsuprine in experimentally induced hypertrophic scar in rabbits. |
2021-10-28 |
2023-08-13 |
Not clear |
| Mohammed J Manna, Muhannad Sami Jalil, Murtadha S Jabu. Topical Isoxsuprine in experimentally induced hypertrophic scar in rabbits. Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique. vol 28. issue 1. 2021-10-28. PMID:34553572. |
different treatment strategies have been tried in their management, but there is no satisfactory option for treating hypertrophic scar currently; moreover the standard steroid therapy is associated with numerous local side effects, and there is a need for researches in new treatment options. |
2021-10-28 |
2023-08-13 |
Not clear |
| Mohammed J Manna, Muhannad Sami Jalil, Murtadha S Jabu. Topical Isoxsuprine in experimentally induced hypertrophic scar in rabbits. Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique. vol 28. issue 1. 2021-10-28. PMID:34553572. |
the aim of this study is to evaluate the role of topical isoxsuprine in experimentally induced hypertrophic scar in rabbits. |
2021-10-28 |
2023-08-13 |
Not clear |
| Wen Shi, Yan Wu, Donghui Bia. p75NTR silencing inhibits proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts by activating autophagy through inhibiting the PI3K/Akt/mTOR pathway. Canadian journal of physiology and pharmacology. vol 99. issue 4. 2021-10-27. PMID:32726570. |
p75ntr silencing inhibits proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts by activating autophagy through inhibiting the pi3k/akt/mtor pathway. |
2021-10-27 |
2023-08-13 |
Not clear |
| Wen Shi, Yan Wu, Donghui Bia. p75NTR silencing inhibits proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts by activating autophagy through inhibiting the PI3K/Akt/mTOR pathway. Canadian journal of physiology and pharmacology. vol 99. issue 4. 2021-10-27. PMID:32726570. |
hypertrophic scar (hs) results from abnormal wound healing, accompanied by excessive hypercellularity, migration, and extracellular matrix (ecm) deposition. |
2021-10-27 |
2023-08-13 |
Not clear |
| Wen Shi, Yan Wu, Donghui Bia. p75NTR silencing inhibits proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts by activating autophagy through inhibiting the PI3K/Akt/mTOR pathway. Canadian journal of physiology and pharmacology. vol 99. issue 4. 2021-10-27. PMID:32726570. |
p75ntr silencing inhibited proliferation, migration, and ecm deposition of hypertrophic scar fibroblasts (hsf), whereas p75ntr overexpression presented the opposite results. |
2021-10-27 |
2023-08-13 |
Not clear |