Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Qinghua Wu, Junjie Chen, Ziming Tan, Dehuai Wang, Jianwen Zhou, Dan Li, Ying Ce. Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) regulates fibroblast growth factor receptor substrate 2 (FRS2) by targeting microRNA (miR)-29-3p in hypertrophic scar fibroblasts. Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34414852. |
long non-coding rna (lncrna) nuclear enriched abundant transcript 1 (neat1) regulates fibroblast growth factor receptor substrate 2 (frs2) by targeting microrna (mir)-29-3p in hypertrophic scar fibroblasts. |
2021-09-27 |
2023-08-13 |
human |
Qinghua Wu, Junjie Chen, Ziming Tan, Dehuai Wang, Jianwen Zhou, Dan Li, Ying Ce. Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) regulates fibroblast growth factor receptor substrate 2 (FRS2) by targeting microRNA (miR)-29-3p in hypertrophic scar fibroblasts. Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34414852. |
however, the detailed role of lncrnas in hypertrophic scar fibroblasts (hsfs) is inadequately understood. |
2021-09-27 |
2023-08-13 |
human |
Qinghua Wu, Junjie Chen, Ziming Tan, Dehuai Wang, Jianwen Zhou, Dan Li, Ying Ce. Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) regulates fibroblast growth factor receptor substrate 2 (FRS2) by targeting microRNA (miR)-29-3p in hypertrophic scar fibroblasts. Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34414852. |
in conclusion, neat1 knockdown protected against hypertrophic scarring by modulating the mir-29-3p/frs2 axis, which is a viable target in scar treatment. |
2021-09-27 |
2023-08-13 |
human |
Quanchen Xu, Yuanxin Miao, Jizheng Ren, Yu Sun, Cong Li, Xia Cai, Zhiguo Wan. Silencing of Nesprin-2 inhibits the differentiation of myofibroblasts from fibroblasts induced by mechanical stretch. International wound journal. 2021-09-24. PMID:34558192. |
mechanical force plays a pivotal role in the pathogenesis of hypertrophic scar (hts). |
2021-09-24 |
2023-08-13 |
human |
Jihong Shi, Shan Shi, Wenbo Xie, Ming Zhao, Yan Li, Jian Zhang, Na Li, Xiaozhi Bai, Weixia Cai, Xiaolong Hu, Dahai Hu, Juntao Han, Hao Gua. IL-10 alleviates lipopolysaccharide-induced skin scarring via IL-10R/STAT3 axis regulating TLR4/NF-κB pathway in dermal fibroblasts. Journal of cellular and molecular medicine. vol 25. issue 3. 2021-09-22. PMID:33410606. |
hypertrophic scar (hs) is a severe fibrotic skin disease. |
2021-09-22 |
2023-08-13 |
Not clear |
Yueming Xue, Chunxiao Qi, Yunsheng Dong, Lin Zhang, Xiangsheng Liu, Yufei Liu, Shufang Wan. Poly (γ-glutamic acid)/chitooligo-saccharide/papain hydrogel prevents hypertrophic scar during skin wound healing. Journal of biomedical materials research. Part B, Applied biomaterials. vol 109. issue 11. 2021-09-22. PMID:33739603. |
poly (γ-glutamic acid)/chitooligo-saccharide/papain hydrogel prevents hypertrophic scar during skin wound healing. |
2021-09-22 |
2023-08-13 |
rabbit |
Yueming Xue, Chunxiao Qi, Yunsheng Dong, Lin Zhang, Xiangsheng Liu, Yufei Liu, Shufang Wan. Poly (γ-glutamic acid)/chitooligo-saccharide/papain hydrogel prevents hypertrophic scar during skin wound healing. Journal of biomedical materials research. Part B, Applied biomaterials. vol 109. issue 11. 2021-09-22. PMID:33739603. |
hypertrophic scar, a common skin disorder typically caused by deep burns or scald were usually treated via surgical resection, laser irradiation, and drugs. |
2021-09-22 |
2023-08-13 |
rabbit |
Jia Huang, Xiaobo Zhou, Lingling Xia, Weiwei Liu, Fei Guo, Jianhui Liu, Wei Li. Inhibition of hypertrophic scar formation with oral asiaticoside treatment in a rabbit ear scar model. International wound journal. vol 18. issue 5. 2021-09-21. PMID:33666348. |
inhibition of hypertrophic scar formation with oral asiaticoside treatment in a rabbit ear scar model. |
2021-09-21 |
2023-08-13 |
rabbit |
Jia Huang, Xiaobo Zhou, Lingling Xia, Weiwei Liu, Fei Guo, Jianhui Liu, Wei Li. Inhibition of hypertrophic scar formation with oral asiaticoside treatment in a rabbit ear scar model. International wound journal. vol 18. issue 5. 2021-09-21. PMID:33666348. |
hypertrophic scar (hs) is a fibrotic skin disease characterised by over-productive collagen and excessive inflammatory reaction, which can be functionally and cosmetically problematic. |
2021-09-21 |
2023-08-13 |
rabbit |
Jangyoun Choi, Yu Na Han, Eun Young Rha, Hwi Ju Kang, Ki Joo Kim, Il Kyu Park, Hyun-Jung Kim, Jong Won Rhi. Verapamil-containing silicone gel reduces scar hypertrophy. International wound journal. vol 18. issue 5. 2021-09-21. PMID:33733593. |
verapamil-containing silicone gel reduces scar hypertrophy. |
2021-09-21 |
2023-08-13 |
rabbit |
Jangyoun Choi, Yu Na Han, Eun Young Rha, Hwi Ju Kang, Ki Joo Kim, Il Kyu Park, Hyun-Jung Kim, Jong Won Rhi. Verapamil-containing silicone gel reduces scar hypertrophy. International wound journal. vol 18. issue 5. 2021-09-21. PMID:33733593. |
a hypertrophic scar is a common dermal fibroproliferative lesion usually treated with topical silicone. |
2021-09-21 |
2023-08-13 |
rabbit |
Ruihong Yuan, Xiaoming Dai, Yisong Li, Chunshan Li, Liu Li. Exosomes from miR-29a-modified adipose-derived mesenchymal stem cells reduce excessive scar formation by inhibiting TGF-β2/Smad3 signaling. Molecular medicine reports. vol 24. issue 5. 2021-09-18. PMID:34476508. |
firstly, the expression of mir‑29a in thermal skin tissues of mice and human hypertrophic scar fibroblasts (hsfbs) was detected via reverse transcription‑quantitative pcr. |
2021-09-18 |
2023-08-13 |
mouse |
Natasha Barone, Tyler Safran, Joshua Vorstenbosch, Peter G Davison, Sabrina Cugno, Amanda M Murph. Current Advances in Hypertrophic Scar and Keloid Management. Seminars in plastic surgery. vol 35. issue 3. 2021-09-17. PMID:34526861. |
current advances in hypertrophic scar and keloid management. |
2021-09-17 |
2023-08-13 |
Not clear |
Seigo Suganuma, Kaoru Tada, Daisuke Yamauchi, Shingo Takagawa, Hidetoshi Yasutake, Keito Shimanuki, Hiroshi Minato, Hiroyuki Tsuchiy. Reverse digital artery flap for Pacinian hypertrophy of the fingertip: A rare case report. JPRAS open. vol 30. 2021-09-16. PMID:34522755. |
haematoxylin and eosin staining of the resected specimen revealed scar tissue with foreign body reaction and mild pacinian hypertrophy. |
2021-09-16 |
2023-08-13 |
Not clear |
Zha Ru, Ying Hu, Shenghua Huang, Li Bai, Kun Zhang, Yue L. Bioflavonoid Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-09-15. PMID:34518767. |
bioflavonoid hypertrophic scar (hs) is a benign fibroproliferative skin disease resulting from an aberrant wound healing process and can cause aesthetic and functional damage to patients. |
2021-09-15 |
2023-08-13 |
Not clear |
Jiahao He, Bin Fang, Shengzhou Shan, Yun Xie, Chuandong Wang, Yifan Zhang, Xiaoling Zhang, Qingfeng L. Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1. Cell death & disease. vol 12. issue 3. 2021-09-14. PMID:33649312. |
mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel piezo1. |
2021-09-14 |
2023-08-13 |
human |
Jiahao He, Bin Fang, Shengzhou Shan, Yun Xie, Chuandong Wang, Yifan Zhang, Xiaoling Zhang, Qingfeng L. Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1. Cell death & disease. vol 12. issue 3. 2021-09-14. PMID:33649312. |
hypertrophic scar (hs) formation is a skin fibroproliferative disease that occurs following a cutaneous injury, leading to functional and cosmetic impairment. |
2021-09-14 |
2023-08-13 |
human |
Jun Huang, Jun Chen, Yan Wo, Xue Wang, Yixin Zhang, Xiangdong Chen, Zhen Zhang, Ewelina Bisku. CO Rejuvenation research. vol 24. issue 2. 2021-09-10. PMID:32578501. |
co the treatment of hypertrophic scar (hs) has thus far been a clinical challenge. |
2021-09-10 |
2023-08-13 |
Not clear |
Yan Li, Jian Zhang, Jihong Shi, Kaituo Liu, Xujie Wang, Yanhui Jia, Ting He, Kuo Shen, Yunchuan Wang, Jiaqi Liu, Wei Zhang, Hongtao Wang, Zhao Zheng, Dahai H. Correction to: Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis. Stem cell research & therapy. vol 12. issue 1. 2021-09-10. PMID:34474691. |
correction to: exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by mir-192-5p/il-17ra/smad axis. |
2021-09-10 |
2023-08-13 |
human |
Xian-Min Li, Wen-Yuan Yu, Qi Chen, Hui-Ru Zhuang, Su-Yue Gao, Tian-Lan Zha. LncRNA TUG1 exhibits pro-fibrosis activity in hypertrophic scar through TAK1/YAP/TAZ pathway via miR-27b-3p. Molecular and cellular biochemistry. vol 476. issue 8. 2021-09-06. PMID:33791919. |
lncrna tug1 exhibits pro-fibrosis activity in hypertrophic scar through tak1/yap/taz pathway via mir-27b-3p. |
2021-09-06 |
2023-08-13 |
Not clear |