| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mariko L Bennett, Angela N Viaen. What are activated and reactive glia and what is their role in neurodegeneration? Neurobiology of disease. vol 148. 2021-03-23. PMID:33171230. |
reactive astrocytes variably undergo process hypertrophy, decrease their normal homeostatic functions such as facilitating synapse formation, and in some cases act to form a tissue scar in response to insult. |
2021-03-23 |
2023-08-13 |
Not clear |
| L Ma, L Y Li, T L Zha. Anti-inflammatory effects of ginsenoside Rg3 on the hypertrophic scar formation via the NF-κB/IκB signaling pathway in rabbit ears. Die Pharmazie. vol 75. issue 2. 2021-03-22. PMID:32213242. |
anti-inflammatory effects of ginsenoside rg3 on the hypertrophic scar formation via the nf-κb/iκb signaling pathway in rabbit ears. |
2021-03-22 |
2023-08-13 |
rabbit |
| L Ma, L Y Li, T L Zha. Anti-inflammatory effects of ginsenoside Rg3 on the hypertrophic scar formation via the NF-κB/IκB signaling pathway in rabbit ears. Die Pharmazie. vol 75. issue 2. 2021-03-22. PMID:32213242. |
the anti-inflammatory effects of rg3 on the hypertrophic scar (hs) formation remain relatively obscure. |
2021-03-22 |
2023-08-13 |
rabbit |
| L Ma, L Y Li, T L Zha. Anti-inflammatory effects of ginsenoside Rg3 on the hypertrophic scar formation via the NF-κB/IκB signaling pathway in rabbit ears. Die Pharmazie. vol 75. issue 2. 2021-03-22. PMID:32213242. |
using histological analyses, we evaluated scar hypertrophy based on the hematoxylin and eosin staining. |
2021-03-22 |
2023-08-13 |
rabbit |
| Ryosuke Nakamura, Shigeyuki Mukudai, Renjie Bing, Michael J Garabedian, Ryan C Bransk. Complex fibroblast response to glucocorticoids may underlie variability of clinical efficacy in the vocal folds. Scientific reports. vol 10. issue 1. 2021-03-22. PMID:33235235. |
similar to the hypertrophic scar and keloids, the efficacy of glucorticoids (gc) for vocal fold injury is highly variable. |
2021-03-22 |
2023-08-13 |
human |
| Jinxia Zhang, Zhikuan Xia, Shuanglin Zhou, Wanting Luo, Zhuoying Peng, Rongya Yan. Effect of Artesunate Combined With Fractional CO Lasers in surgery and medicine. 2021-03-18. PMID:33644924. |
effect of artesunate combined with fractional co hypertrophic scar (hs), a common complication in wound healing, is characterized by the disarrangement of collagen, fibers, and extracellular matrix. |
2021-03-18 |
2023-08-13 |
Not clear |
| Carolina Maria Costa de Oliveira Souza, Clayton Fernandes de Souza, Bassam Felipe Mogharbel, Ana Carolina Irioda, Celia Regina Cavichiolo Franco, Maria Rita Sierakowski, Katherine Athayde Teixeira de Carvalh. Nanostructured Cellulose-Gellan-Xyloglucan-Lysozyme Dressing Seeded with Mesenchymal Stem Cells for Deep Second-Degree Burn Treatment. International journal of nanomedicine. vol 16. 2021-03-12. PMID:33584096. |
in deep burns, wound contraction and hypertrophic scar formation can generate functional derangement and debilitation of the affected part. |
2021-03-12 |
2023-08-13 |
Not clear |
| Thijs C H Oosterhoff, Vivian K Beekman, Jelle P van der List, Frank B Niesse. Laser treatment of specific scar characteristics in hypertrophic scars and keloid: A systematic review. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. vol 74. issue 1. 2021-03-08. PMID:33645505. |
laser treatment of specific scar characteristics in hypertrophic scars and keloid: a systematic review. |
2021-03-08 |
2023-08-13 |
Not clear |
| Ying Zhou, Yuexin Sun, Wenjun Hou, Liwen Ma, Yue Tao, Dan Li, Cui Xu, Jun Bao, Weixin Fa. The JAK2/STAT3 pathway inhibitor, AG490, suppresses the abnormal behavior of keloid fibroblasts in vitro. International journal of molecular medicine. vol 46. issue 1. 2021-03-05. PMID:32377718. |
the effects of ag490 on tgf‑β‑stimulated fibroblasts, including hnfs, hkfs and hypertrophic scar fibroblasts (hsfs) were also evaluated. |
2021-03-05 |
2023-08-13 |
human |
| B Y Guo, D W Jiang, Q Hui, J Chai, K Ta. [Expression and effect of microRNA-205 in human hypertrophic scar]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 37. issue 2. 2021-03-03. PMID:33648329. |
[expression and effect of microrna-205 in human hypertrophic scar]. |
2021-03-03 |
2023-08-13 |
human |
| Yu Zhou, Tianfeng Hua, Xiaojuan Weng, Dameng Ma, Xiaojing L. Calcitonin gene-related peptide alleviates hypertrophic scar formation by inhibiting the inflammation. Archives of dermatological research. 2021-03-02. PMID:33649909. |
calcitonin gene-related peptide alleviates hypertrophic scar formation by inhibiting the inflammation. |
2021-03-02 |
2023-08-13 |
mouse |
| Yu Zhou, Tianfeng Hua, Xiaojuan Weng, Dameng Ma, Xiaojing L. Calcitonin gene-related peptide alleviates hypertrophic scar formation by inhibiting the inflammation. Archives of dermatological research. 2021-03-02. PMID:33649909. |
the present study aims to explore the roles of calcitonin gene-related peptide (cgrp) in the hypertrophic scar and its underlying mechanism. |
2021-03-02 |
2023-08-13 |
mouse |
| Yu Zhou, Tianfeng Hua, Xiaojuan Weng, Dameng Ma, Xiaojing L. Calcitonin gene-related peptide alleviates hypertrophic scar formation by inhibiting the inflammation. Archives of dermatological research. 2021-03-02. PMID:33649909. |
the levels of cgrp were determined in human hypertrophic scar and mouse cutaneous scar using elisa and western blot. |
2021-03-02 |
2023-08-13 |
mouse |
| Yu Zhou, Tianfeng Hua, Xiaojuan Weng, Dameng Ma, Xiaojing L. Calcitonin gene-related peptide alleviates hypertrophic scar formation by inhibiting the inflammation. Archives of dermatological research. 2021-03-02. PMID:33649909. |
elevated levels of cgrp were observed in the hypertrophic scar. |
2021-03-02 |
2023-08-13 |
mouse |
| Deena Hadedeya, Mahmoud Shalaby, Mounika Akkera, Grace Lee, Kendra Harris, Roostam Kholmatov, Muhammad Anwar, Fadi Murad, Saad Alawaad, Emad Kandi. Prophylactic external beam radiation therapy for keloid prevention in thyroid surgery patients. Gland surgery. vol 10. issue 1. 2021-02-27. PMID:33633963. |
poor cosmesis, secondary to keloid or hypertrophic scar, following thyroid surgery may cause considerable patient distress and be a significant challenge to treat. |
2021-02-27 |
2023-08-13 |
Not clear |
| Tao Zhang, Xiao-Feng Wang, Zheng-Cai Wang, Dong Lou, Qing-Qing Fang, Yan-Yan Hu, Wan-Yi Zhao, Li-Yun Zhang, Li-Hong Wu, Wei-Qiang Ta. Current potential therapeutic strategies targeting the TGF-β/Smad signaling pathway to attenuate keloid and hypertrophic scar formation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 129. 2021-02-26. PMID:32540643. |
current potential therapeutic strategies targeting the tgf-β/smad signaling pathway to attenuate keloid and hypertrophic scar formation. |
2021-02-26 |
2023-08-13 |
Not clear |
| Tao Zhang, Xiao-Feng Wang, Zheng-Cai Wang, Dong Lou, Qing-Qing Fang, Yan-Yan Hu, Wan-Yi Zhao, Li-Yun Zhang, Li-Hong Wu, Wei-Qiang Ta. Current potential therapeutic strategies targeting the TGF-β/Smad signaling pathway to attenuate keloid and hypertrophic scar formation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 129. 2021-02-26. PMID:32540643. |
aberrant scar formation, which includes keloid and hypertrophic scars, is associated with a pathological disorganized wound healing process with chronic inflammation. |
2021-02-26 |
2023-08-13 |
Not clear |
| Su-Ben Tsao, Cheng-Chun W. Silicone Breast Implant Injector: A Retooled Breast Augmentation Device. Aesthetic plastic surgery. vol 45. issue 1. 2021-02-25. PMID:32978659. |
there are some complications, including need to ensure that the incision is long enough for the implant to be inserted, scar hypertrophy caused by implant insertion friction damage to the edge of incision, and the occasional need to ask the surgical assistant to lend more fingers to facilitate satisfactory insertion and placement. |
2021-02-25 |
2023-08-13 |
Not clear |
| Susan C Campbell, Carmen Muñoz-Ballester, Lata Chaunsali, William A Mills, Jennifer H Yang, Harald Sontheimer, Stefanie Robe. Potassium and glutamate transport is impaired in scar-forming tumor-associated astrocytes. Neurochemistry international. vol 133. 2021-02-23. PMID:31825815. |
using electrophysiology, immunohistochemistry, fluorescent in situ hybridization, and western blot analysis in different orthotopic xenograft and allograft models of human and mouse gliomas, we find that peritumoral astrocytes exhibit astrocyte scar formation characterized by proliferation, cellular hypertrophy, process elongation, and increased gfap and pstat3. |
2021-02-23 |
2023-08-13 |
mouse |
| Nihui Zhang, Tao Gao, Yao Wang, Juan Liu, Junwei Zhang, Ruijuan Yao, Fang W. Modulating cationicity of chitosan hydrogel to prevent hypertrophic scar formation during wound healing. International journal of biological macromolecules. vol 154. 2021-02-19. PMID:32194120. |
modulating cationicity of chitosan hydrogel to prevent hypertrophic scar formation during wound healing. |
2021-02-19 |
2023-08-13 |
Not clear |