| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tarik D Madni, Karen Lu, Paul A Nakonezny, Jonathan B Imran, Holly B Cunningham, Audra T Clark, Luis Taveras, John E Hoopman, Steven E Wolf, Jeffrey M Kenkel, Herb A Phela. Treating Hypertrophic Burn Scar With 2940-nm Er:YAG Laser Fractional Ablation Improves Scar Characteristics as Measured by Noninvasive Technology. Journal of burn care & research : official publication of the American Burn Association. vol 40. issue 4. 2020-10-14. PMID:31046088. |
their group previously demonstrated high-patient satisfaction for the treatment of hypertrophic burn scar (hbs) with the erbium: yttrium aluminum garnet (er:yag) laser, but this and other literature supporting the practice suffer from a common weakness of a reliance on subjective assessments by patients or providers. |
2020-10-14 |
2023-08-13 |
Not clear |
| Sagar P Patel, Ha Vi Nguyen, Diana Mannschreck, Richard J Redett, Katherine B Puttgen, F Dylan Stewar. Fractional CO2 Laser Treatment Outcomes for Pediatric Hypertrophic Burn Scars. Journal of burn care & research : official publication of the American Burn Association. vol 40. issue 4. 2020-10-14. PMID:31225898. |
these findings demonstrate that co2-afl can improve hypertrophic burn scars in pediatric patients providing a lower risk alternative to invasive therapies and a more immediate, efficacious alternative to more conservative scar treatments. |
2020-10-14 |
2023-08-13 |
Not clear |
| Junnan Chen, Zhihua Li, Zhenya Huang, Liming Liang, Minliang Che. Chyle Fat-Derived Stem Cells Conditioned Medium Inhibits Hypertrophic Scar Fibroblast Activity. Annals of plastic surgery. vol 83. issue 3. 2020-10-13. PMID:31149905. |
chyle fat-derived stem cells conditioned medium inhibits hypertrophic scar fibroblast activity. |
2020-10-13 |
2023-08-13 |
human |
| Chen Fan, Lay Keng Priscilla Lim, Zihao Wu, Bhavya Sharma, Shi Qi Gan, Kun Liang, Zee Upton, David Leavesle. In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding. Journal of visualized experiments : JoVE. issue 159. 2020-10-09. PMID:32420993. |
as hypertrophic scarring arises from the excessive deposition of collagen, this protocol aims to construct a collagen-rich in vitro hypertrophic scar model by applying the mmc technique with hhsfs. |
2020-10-09 |
2023-08-13 |
human |
| Yaping Zhang, Qin Deng, Longxiang Tu, Dan Lv, Dewu Li. tRNA‑derived small RNAs: A novel class of small RNAs in human hypertrophic scar fibroblasts. International journal of molecular medicine. vol 45. issue 1. 2020-10-05. PMID:31939611. |
trna‑derived small rnas: a novel class of small rnas in human hypertrophic scar fibroblasts. |
2020-10-05 |
2023-08-13 |
human |
| Yaping Zhang, Qin Deng, Longxiang Tu, Dan Lv, Dewu Li. tRNA‑derived small RNAs: A novel class of small RNAs in human hypertrophic scar fibroblasts. International journal of molecular medicine. vol 45. issue 1. 2020-10-05. PMID:31939611. |
the present study investigated differentially expressed tsrnas in human hypertrophic scar fibroblasts and normal skin fibroblasts via high‑throughput sequencing. |
2020-10-05 |
2023-08-13 |
human |
| Yaping Zhang, Qin Deng, Longxiang Tu, Dan Lv, Dewu Li. tRNA‑derived small RNAs: A novel class of small RNAs in human hypertrophic scar fibroblasts. International journal of molecular medicine. vol 45. issue 1. 2020-10-05. PMID:31939611. |
in total, 67 differentially expressed tsrnas were detected, of which 27 were upregulated and 40 downregulated in hypertrophic scar fibroblasts. |
2020-10-05 |
2023-08-13 |
human |
| Yaping Zhang, Qin Deng, Longxiang Tu, Dan Lv, Dewu Li. tRNA‑derived small RNAs: A novel class of small RNAs in human hypertrophic scar fibroblasts. International journal of molecular medicine. vol 45. issue 1. 2020-10-05. PMID:31939611. |
microrna (mir)‑29b‑1‑5p was identified as a target of tsrna‑23678 and was downregulated in hypertrophic scar fibroblasts, constituting a negative regulatory factor for scar formation. |
2020-10-05 |
2023-08-13 |
human |
| Yaping Zhang, Qin Deng, Longxiang Tu, Dan Lv, Dewu Li. tRNA‑derived small RNAs: A novel class of small RNAs in human hypertrophic scar fibroblasts. International journal of molecular medicine. vol 45. issue 1. 2020-10-05. PMID:31939611. |
collectively, these findings reveal that tsrnas are differentially expressed in human hypertrophic scar fibroblasts, and may contribute to the molecular mechanism and treatment of hypertrophic scars. |
2020-10-05 |
2023-08-13 |
human |
| Mengyao Tang, Wenbo Wang, Liying Cheng, Rong Jin, Lu Zhang, Weiwei Bian, Yuguang Zhan. The inhibitory effects of 20(R)-ginsenoside Rg3 on the proliferation, angiogenesis, and collagen synthesis of hypertrophic scar derived fibroblasts Iranian journal of basic medical sciences. vol 21. issue 3. 2020-10-01. PMID:29511498. |
the inhibitory effects of 20(r)-ginsenoside rg3 on the proliferation, angiogenesis, and collagen synthesis of hypertrophic scar derived fibroblasts therapeutic effect of many selectable methods applied in clinical practice for treating hypertrophic scar (hs) is not still so satisfactory. |
2020-10-01 |
2023-08-13 |
Not clear |
| I Mataro, G Delli Santi, P Palombo, R D'Alessio, M Vestit. Spontaneous healing and scar control following enzymatic debridement of deep second-degree burns. Annals of burns and fire disasters. vol 30. issue 4. 2020-10-01. PMID:29983689. |
the hypertrophic scar represents the most common type of cicatrix after burns, and it has a prevalence of up to 70%. |
2020-10-01 |
2023-08-13 |
Not clear |
| I Mataro, G Delli Santi, P Palombo, R D'Alessio, M Vestit. Spontaneous healing and scar control following enzymatic debridement of deep second-degree burns. Annals of burns and fire disasters. vol 30. issue 4. 2020-10-01. PMID:29983689. |
the pathophysiology of hypertrophic scar formation is based on the perturbation of collagen production or degradation or both. |
2020-10-01 |
2023-08-13 |
Not clear |
| Haihan Chu, Yunpeng Wang, Xiuchun Wang, Xianhui Song, Huaqing Liu, Xue L. Effects of transplanted adipose derived stem cells on the expressions of α-SMA and DCN in fibroblasts of hypertrophic scar tissues in rabbit ears. Experimental and therapeutic medicine. vol 16. issue 3. 2020-10-01. PMID:30186394. |
effects of transplanted adipose derived stem cells on the expressions of α-sma and dcn in fibroblasts of hypertrophic scar tissues in rabbit ears. |
2020-10-01 |
2023-08-13 |
rabbit |
| Haihan Chu, Yunpeng Wang, Xiuchun Wang, Xianhui Song, Huaqing Liu, Xue L. Effects of transplanted adipose derived stem cells on the expressions of α-SMA and DCN in fibroblasts of hypertrophic scar tissues in rabbit ears. Experimental and therapeutic medicine. vol 16. issue 3. 2020-10-01. PMID:30186394. |
to study the effects of transplanted adipose derived stem cells (adscs) on the expressions of α-smooth muscle actin (α-sma) and decorin (dcn) in fibroblasts of hypertrophic scar tissues in rabbit ears. |
2020-10-01 |
2023-08-13 |
rabbit |
| N G Elmelegy, A M Hegazy, M S Sadaka, D E Abdeldai. Electrophotobiomodulation in the treatment of facial post-burn hypertrophic scars in pediatric patients. Annals of burns and fire disasters. vol 31. issue 2. 2020-10-01. PMID:30374265. |
hypertrophic scar continues to be one of the leading reasons for surgical and non-surgical treatments after burn healing. |
2020-10-01 |
2023-08-13 |
Not clear |
| A Ibrahim, R S Chalhou. 5-fu for problematic scarring: a review of the literature. Annals of burns and fire disasters. vol 31. issue 2. 2020-10-01. PMID:30374266. |
current evidence suggests that 5-fu is effective in treating keloids and hypertrophic scars, but further research must be done to correlate therapeutic response with the age of the scar. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jun Qi, Yifei Liu, Kesu Hu, Yi Zhang, Yangyang Wu, Xia Zhan. MicroRNA-205-5p regulates extracellular matrix production in hyperplastic scars by targeting Smad2. Experimental and therapeutic medicine. vol 17. issue 3. 2020-10-01. PMID:30867712. |
hypertrophic scar (hs) formation is the result of poor skin-wound healing. |
2020-10-01 |
2023-08-13 |
human |
| Jun Qi, Yifei Liu, Kesu Hu, Yi Zhang, Yangyang Wu, Xia Zhan. MicroRNA-205-5p regulates extracellular matrix production in hyperplastic scars by targeting Smad2. Experimental and therapeutic medicine. vol 17. issue 3. 2020-10-01. PMID:30867712. |
mir-205-5p expression was decreased in hs tissues and human hypertrophic scar fibroblasts (hhsfs). |
2020-10-01 |
2023-08-13 |
human |
| Jie Ren, Yifei Lu, Yanhong Qian, Bozhou Chen, Tao Wu, Guang J. Recent progress regarding kaempferol for the treatment of various diseases. Experimental and therapeutic medicine. vol 18. issue 4. 2020-10-01. PMID:31572524. |
in addition, it has beneficial effects against cancer, liver injury, obesity and diabetes, inhibits vascular endothelial inflammation, protects the cranial nerve and heart function, and may be used for treating fibroproliferative disorders, including hypertrophic scar. |
2020-10-01 |
2023-08-13 |
Not clear |
| Rei Ogawa, Sadanori Akita, Satoshi Akaishi, Noriko Aramaki-Hattori, Teruyuki Dohi, Toshihiko Hayashi, Kazuo Kishi, Taro Kono, Hajime Matsumura, Gan Muneuchi, Naoki Murao, Munetomo Nagao, Keisuke Okabe, Fumiaki Shimizu, Mamiko Tosa, Yasuyoshi Tosa, Satoko Yamawaki, Shinichi Ansai, Norihisa Inazu, Toshiko Kamo, Reiko Kazki, Shigehiko Kuribayash. Diagnosis and Treatment of Keloids and Hypertrophic Scars-Japan Scar Workshop Consensus Document 2018. Burns & trauma. vol 7. 2020-10-01. PMID:31890718. |
diagnosis and treatment of keloids and hypertrophic scars-japan scar workshop consensus document 2018. |
2020-10-01 |
2023-08-13 |
Not clear |