| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xingwang Deng, Qian Chen, Lijuan Qiang, Mingwei Chi, Nan Xie, Yinsheng Wu, Ming Yao, Dan Zhao, Jiaxiang Ma, Ning Zhang, Yan Xi. Development of a Porcine Full-Thickness Burn Hypertrophic Scar Model and Investigation of the Effects of Shikonin on Hypertrophic Scar Remediation. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:29922164. |
development of effective scar therapies relies on validated animal models that mimic human hypertrophic scars. |
2020-09-30 |
2023-08-13 |
human |
| Xingwang Deng, Qian Chen, Lijuan Qiang, Mingwei Chi, Nan Xie, Yinsheng Wu, Ming Yao, Dan Zhao, Jiaxiang Ma, Ning Zhang, Yan Xi. Development of a Porcine Full-Thickness Burn Hypertrophic Scar Model and Investigation of the Effects of Shikonin on Hypertrophic Scar Remediation. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:29922164. |
a consistent porcine full-thickness burn hypertrophic scar model has yet to be developed. |
2020-09-30 |
2023-08-13 |
human |
| Xingwang Deng, Qian Chen, Lijuan Qiang, Mingwei Chi, Nan Xie, Yinsheng Wu, Ming Yao, Dan Zhao, Jiaxiang Ma, Ning Zhang, Yan Xi. Development of a Porcine Full-Thickness Burn Hypertrophic Scar Model and Investigation of the Effects of Shikonin on Hypertrophic Scar Remediation. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:29922164. |
we have previously reported that shikonin induces apoptosis and reduces collagen production in hypertrophic scar fibroblasts |
2020-09-30 |
2023-08-13 |
human |
| Mi Young Lee, Eun Shin, Hyunchul Kim, In Suk Kwak, Younghee Cho. Interleukin-31, Interleukin-31RA, and OSMR Expression Levels in Post-burn Hypertrophic Scars. Journal of pathology and translational medicine. vol 52. issue 5. 2020-09-30. PMID:30114861. |
therefore, the histopathological expression levels of il-31, il-31 receptor alpha (il-31ra), and oncostatin m receptor (osmr) in post-burn hypertrophic scar tissues were investigated and compared with normal tissue expression levels. |
2020-09-30 |
2023-08-13 |
Not clear |
| Qi Chen, Tianlan Zhao, Xiaoming Xie, Daojiang Yu, Lijun Wu, Wenyuan Yu, Wei Su. MicroRNA-663 regulates the proliferation of fibroblasts in hypertrophic scars via transforming growth factor-β1. Experimental and therapeutic medicine. vol 16. issue 2. 2020-09-30. PMID:30116380. |
the present study determined the expression of microrna (mir)-663 in hypertrophic scar (hs) tissues and investigate the regulatory mechanisms of mir-663 in hs. |
2020-09-30 |
2023-08-13 |
Not clear |
| Mark J Landau, Zoe E Birnbaum, Lauren G Kurtz, Joel A Aronowit. Review: Proposed Methods to Improve the Survival of Adipose Tissue in Autologous Fat Grafting. Plastic and reconstructive surgery. Global open. vol 6. issue 8. 2020-09-30. PMID:30324057. |
recognition of other regenerative effects of fat grafting expanded the use afg for improvement of hypertrophic scar tissue, postradiation sequelae, lipodystrophy, hyperpigmentation, senile skin changes, and actinic damage. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yi Feng, Zi-Li Sun, Si-Yu Liu, Jun-Jie Wu, Bin-Hong Zhao, Guo-Zhong Lv, Yong Du, Shun Yu, Ming-Lie Yang, Feng-Lai Yuan, Xiao-Jin Zho. Direct and Indirect Roles of Macrophages in Hypertrophic Scar Formation. Frontiers in physiology. vol 10. 2020-09-30. PMID:31555142. |
direct and indirect roles of macrophages in hypertrophic scar formation. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yi Feng, Zi-Li Sun, Si-Yu Liu, Jun-Jie Wu, Bin-Hong Zhao, Guo-Zhong Lv, Yong Du, Shun Yu, Ming-Lie Yang, Feng-Lai Yuan, Xiao-Jin Zho. Direct and Indirect Roles of Macrophages in Hypertrophic Scar Formation. Frontiers in physiology. vol 10. 2020-09-30. PMID:31555142. |
a variety of cell types are involved in hypertrophic scar formation after wound healing, but the underlying molecular mechanisms and cellular origins of hypertrophic scars are not fully understood. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yi Feng, Zi-Li Sun, Si-Yu Liu, Jun-Jie Wu, Bin-Hong Zhao, Guo-Zhong Lv, Yong Du, Shun Yu, Ming-Lie Yang, Feng-Lai Yuan, Xiao-Jin Zho. Direct and Indirect Roles of Macrophages in Hypertrophic Scar Formation. Frontiers in physiology. vol 10. 2020-09-30. PMID:31555142. |
this review intends to summarize the direct and indirect roles of macrophages during hypertrophic scar formation. |
2020-09-30 |
2023-08-13 |
Not clear |
| Shoujie Wang, Caiyun Li, Yijia Yu, Jianjun Qia. Decreased expression of microRNA-145 promotes the biological functions of fibroblasts in hypertrophic scar tissues by upregulating the expression of transcription factor SOX-9. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31602220. |
decreased expression of microrna-145 promotes the biological functions of fibroblasts in hypertrophic scar tissues by upregulating the expression of transcription factor sox-9. |
2020-09-30 |
2023-08-13 |
Not clear |
| Shoujie Wang, Caiyun Li, Yijia Yu, Jianjun Qia. Decreased expression of microRNA-145 promotes the biological functions of fibroblasts in hypertrophic scar tissues by upregulating the expression of transcription factor SOX-9. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31602220. |
a total of 36 patients who were diagnosed with hypertrophic scar were included in the present study. |
2020-09-30 |
2023-08-13 |
Not clear |
| Shoujie Wang, Caiyun Li, Yijia Yu, Jianjun Qia. Decreased expression of microRNA-145 promotes the biological functions of fibroblasts in hypertrophic scar tissues by upregulating the expression of transcription factor SOX-9. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31602220. |
the present study demonstrated that mir-145 expression is reduced in hypertrophic scar tissues and negatively associated with sox-9 expression. |
2020-09-30 |
2023-08-13 |
Not clear |
| Jun Hyuk Son, Joon Hyuk Choi, Su-Ho Li. Hypertrophic scar of the conjunctiva presenting as an eyelid mass: an unusual complication after surgical treatment of a chalazion. SpringerPlus. vol 5. issue 1. 2020-09-30. PMID:27752457. |
hypertrophic scar of the conjunctiva presenting as an eyelid mass: an unusual complication after surgical treatment of a chalazion. |
2020-09-30 |
2023-08-13 |
Not clear |
| Jun Hyuk Son, Joon Hyuk Choi, Su-Ho Li. Hypertrophic scar of the conjunctiva presenting as an eyelid mass: an unusual complication after surgical treatment of a chalazion. SpringerPlus. vol 5. issue 1. 2020-09-30. PMID:27752457. |
to present a rare case of a conjunctival hypertrophic scar presenting as eyelid mass after surgical treatment of a chalazion. |
2020-09-30 |
2023-08-13 |
Not clear |
| Zhouna Li, Zhehu Ji. Comparative effect and safety of verapamil in keloid and hypertrophic scar treatment: a meta-analysis. Therapeutics and clinical risk management. vol 12. 2020-09-30. PMID:27877046. |
comparative effect and safety of verapamil in keloid and hypertrophic scar treatment: a meta-analysis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Amber R Hackett, Jae K Le. Understanding the NG2 Glial Scar after Spinal Cord Injury. Frontiers in neurology. vol 7. 2020-09-30. PMID:27895617. |
similar to astrocytes, these cells hypertrophy, upregulate expression of chondroitin sulfate proteoglycans, inhibit axon regeneration, contribute to the glial-fibrotic scar border, and some even differentiate into astrocytes. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ali Akbar Mohammadi, Shima Eskandari, Hamed Ghoddusi Johari, Ata'ollah Rajabneja. Using Amniotic Membrane as a Novel Method to Reduce Post-burn Hypertrophic Scar Formation: A Prospective Follow-up Study. Journal of cutaneous and aesthetic surgery. vol 10. issue 1. 2020-09-30. PMID:28529415. |
using amniotic membrane as a novel method to reduce post-burn hypertrophic scar formation: a prospective follow-up study. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ali Akbar Mohammadi, Shima Eskandari, Hamed Ghoddusi Johari, Ata'ollah Rajabneja. Using Amniotic Membrane as a Novel Method to Reduce Post-burn Hypertrophic Scar Formation: A Prospective Follow-up Study. Journal of cutaneous and aesthetic surgery. vol 10. issue 1. 2020-09-30. PMID:28529415. |
in this follow-up study, we aimed to evaluate the possible role of amniotic membrane as an adjunct to split thickness skin grafting on reducing itching and severity of hypertrophic scar formation. |
2020-09-30 |
2023-08-13 |
Not clear |
| b' Zrinka Bukvi\\xc4\\x87 Mokos, Anamaria Jovi\\xc4\\x87, Lovorka Grgurevi\\xc4\\x87, Ivo Dumi\\xc4\\x87-\\xc4\\x8cule, Kre\\xc5\\xa1imir Kostovi\\xc4\\x87, Romana \\xc4\\x8ceovi\\xc4\\x87, Branka Marinovi\\xc4\\x8. Current Therapeutic Approach to Hypertrophic Scars. Frontiers in medicine. vol 4. 2020-09-30. PMID:28676850.' |
that is why the apprehension of regular and controlled physiological processes of scar formation is of utmost importance when facing hypertrophic scarring, its pathophysiology, prevention, and therapeutic approach. |
2020-09-30 |
2023-08-13 |
Not clear |
| Hongming Chen, Yanwen Xu, Guanbin Yang, Qianqian Zhang, Xun Huang, Liming Yu, Xianglin Don. Mast cell chymase promotes hypertrophic scar fibroblast proliferation and collagen synthesis by activating TGF-β1/Smads signaling pathway. Experimental and therapeutic medicine. vol 14. issue 5. 2020-09-30. PMID:29104654. |
mast cell chymase promotes hypertrophic scar fibroblast proliferation and collagen synthesis by activating tgf-β1/smads signaling pathway. |
2020-09-30 |
2023-08-13 |
Not clear |