| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fang Ma, Jiangyong Shen, Hui Zhang, Zhenghao Zhang, Anning Yang, Jiantuan Xiong, Yun Jiao, Zhigang Bai, Shengchao Ma, Huiping Zhang, Yideng Jian. A novel lncRNA FPASL regulates fibroblast proliferation via the PI3K/AKT and MAPK signaling pathways in hypertrophic scar. Acta biochimica et biophysica Sinica. 2022-09-09. PMID:36082934. |
in this study, a novel fibroblast proliferation-associated lncrna, named lncrna fpasl (mstrg.389905.1), which is mainly localized in the cytoplasm, is found to be downregulated in hypertrophic scar, as detected by lncrna microarray and qrt-pcr. |
2022-09-09 |
2023-08-14 |
Not clear |
| Fang Ma, Jiangyong Shen, Hui Zhang, Zhenghao Zhang, Anning Yang, Jiantuan Xiong, Yun Jiao, Zhigang Bai, Shengchao Ma, Huiping Zhang, Yideng Jian. A novel lncRNA FPASL regulates fibroblast proliferation via the PI3K/AKT and MAPK signaling pathways in hypertrophic scar. Acta biochimica et biophysica Sinica. 2022-09-09. PMID:36082934. |
our findings contribute to a better understanding of the role of lncrnas in hypertrophic scar and suggest that fpasl may act as a potential novel therapeutic target for hypertrophic scar. |
2022-09-09 |
2023-08-14 |
Not clear |
| Brenda LaTowsky, David W Robertson, Christopher C Capell. Long-term improvement in the appearance of hypertrophic scars following a single treatment with acoustic subcision-A single center proof-of-concept study. Lasers in surgery and medicine. 2022-09-07. PMID:36069160. |
fibrosis, including hypertrophic scar formation, is a pathological condition characterized by excessive production and accumulation of collagen, and loss of tissue architecture, in response to wound healing. |
2022-09-07 |
2023-08-14 |
human |
| Brenda LaTowsky, David W Robertson, Christopher C Capell. Long-term improvement in the appearance of hypertrophic scars following a single treatment with acoustic subcision-A single center proof-of-concept study. Lasers in surgery and medicine. 2022-09-07. PMID:36069160. |
the acoustic subcision device uses rapid acoustic pulse technology to noninvasively improve the appearance of hypertrophic scars through both microdisruption of scar tissue matrix and downregulation of fibrotic fibroblasts leading to scar remodeling. |
2022-09-07 |
2023-08-14 |
human |
| Li Ma, Lei Hua, Wenyuan Yu, Li Ke, Liang-Yong L. TSG-6 inhibits hypertrophic scar fibroblast proliferation by regulating IRE1α/TRAF2/NF-κB signalling. International wound journal. 2022-09-03. PMID:36056472. |
tsg-6 inhibits hypertrophic scar fibroblast proliferation by regulating ire1α/traf2/nf-κb signalling. |
2022-09-03 |
2023-08-14 |
human |
| Li Ma, Lei Hua, Wenyuan Yu, Li Ke, Liang-Yong L. TSG-6 inhibits hypertrophic scar fibroblast proliferation by regulating IRE1α/TRAF2/NF-κB signalling. International wound journal. 2022-09-03. PMID:36056472. |
tnf-stimulated gene (tsg-6) was reported to suppress hypertrophic scar (hs) formation in a rabbit ear model, and the overexpression of tsg-6 in human hs fibroblasts (hsfs) was found to induce their apoptotic death. |
2022-09-03 |
2023-08-14 |
human |
| Yul Hee Kim, Hyeung Kyoo Kim, Jee Woong Choi, You Chan Ki. Photobiomodulation therapy with an 830-nm light-emitting diode for the prevention of thyroidectomy scars: a randomized, double-blind, sham device-controlled clinical trial. Lasers in medical science. 2022-08-31. PMID:36045183. |
in conclusion, early application of 830-nm led-based photobiomodulation treatment significantly prevents hypertrophic scar formation and reduces postoperative pain without noticeable adverse effects. |
2022-08-31 |
2023-08-14 |
human |
| Haowei Lu, Hui Wang, Guohua Huang, Xuchao Wang, Xiaolin B. Therapeutic targeting of mechanical stretch-induced FAK/ERK signaling by fisetin in hypertrophic scars. European journal of pharmacology. 2022-08-25. PMID:36007606. |
mechanical stress has been proven to be crucial for hypertrophic scar (hs) formation. |
2022-08-25 |
2023-08-14 |
mouse |
| Chuang Yin, Shixi Zhang, Chen Ya, Chuandong Wang, Yimin Liang, Chen Wan. sncRNA changes induced by tension in hypertrophic scar. Acta biochimica et biophysica Sinica. 2022-08-19. PMID:35983974. |
sncrna changes induced by tension in hypertrophic scar. |
2022-08-19 |
2023-08-14 |
Not clear |
| Lingren Wang, Tao Gong, Weihua Ming, Xinglong Qiao, Wei Ye, Linna Zhang, ChangJiang Pa. One step preparation of multifunctional poly (ether sulfone) thin films with potential for wound dressing. Biomaterials advances. vol 136. 2022-08-05. PMID:35929327. |
in addition, the mpfs were capable of modulating the expression level of basic fibroblast growth factor (bfgf) and transforming growth factor-beta1 (tgf-β1) in fibroblast, which was beneficial to controlling the formation of hypertrophic scar. |
2022-08-05 |
2023-08-14 |
human |
| Liya Yang, Huihui Deng, Yiman Chen, Yuling Chen, Ling Guo, Min Fen. 5-Aminolevulinic Acid-Hyaluronic Acid Complexes Enhance Skin Retention of 5-Aminolevulinic Acid and Therapeutic Efficacy in the Treatment of Hypertrophic Scar. AAPS PharmSciTech. vol 23. issue 6. 2022-08-04. PMID:35927520. |
5-aminolevulinic acid-hyaluronic acid complexes enhance skin retention of 5-aminolevulinic acid and therapeutic efficacy in the treatment of hypertrophic scar. |
2022-08-04 |
2023-08-14 |
human |
| Liya Yang, Huihui Deng, Yiman Chen, Yuling Chen, Ling Guo, Min Fen. 5-Aminolevulinic Acid-Hyaluronic Acid Complexes Enhance Skin Retention of 5-Aminolevulinic Acid and Therapeutic Efficacy in the Treatment of Hypertrophic Scar. AAPS PharmSciTech. vol 23. issue 6. 2022-08-04. PMID:35927520. |
hypertrophic scar is a serious skin disorder, which reduces the patient's quality of life. |
2022-08-04 |
2023-08-14 |
human |
| Liya Yang, Huihui Deng, Yiman Chen, Yuling Chen, Ling Guo, Min Fen. 5-Aminolevulinic Acid-Hyaluronic Acid Complexes Enhance Skin Retention of 5-Aminolevulinic Acid and Therapeutic Efficacy in the Treatment of Hypertrophic Scar. AAPS PharmSciTech. vol 23. issue 6. 2022-08-04. PMID:35927520. |
5-aminolevulinic acid (5-ala)-mediated photodynamic therapy has been used to treat patients with hypertrophic scar. |
2022-08-04 |
2023-08-14 |
human |
| Liya Yang, Huihui Deng, Yiman Chen, Yuling Chen, Ling Guo, Min Fen. 5-Aminolevulinic Acid-Hyaluronic Acid Complexes Enhance Skin Retention of 5-Aminolevulinic Acid and Therapeutic Efficacy in the Treatment of Hypertrophic Scar. AAPS PharmSciTech. vol 23. issue 6. 2022-08-04. PMID:35927520. |
and then, the accumulative ppix induced by 5-ala-ha in human hypertrophic scar fibroblasts (hsf) was triggered by laser irradiation to produce sufficient reactive oxygen species, leading to efficient necrosis and apoptosis of hsf. |
2022-08-04 |
2023-08-14 |
human |
| Liya Yang, Huihui Deng, Yiman Chen, Yuling Chen, Ling Guo, Min Fen. 5-Aminolevulinic Acid-Hyaluronic Acid Complexes Enhance Skin Retention of 5-Aminolevulinic Acid and Therapeutic Efficacy in the Treatment of Hypertrophic Scar. AAPS PharmSciTech. vol 23. issue 6. 2022-08-04. PMID:35927520. |
therefore, the 5-ala-ha complex enhancing skin retention and ppix accumulation at the lesion site provide a promising therapeutic strategy for hypertrophic scar. |
2022-08-04 |
2023-08-14 |
human |
| Yuan Fang, Yu Han, Shoubao Wang, Jingting Chen, Kerong Dai, Yao Xiong, Binbin Su. Three-dimensional printing bilayer membranous nanofiber scaffold for inhibiting scar hyperplasia of skin. Biomaterials advances. vol 138. 2022-08-01. PMID:35913242. |
hypertrophic scar (hs) is the manifestation of pathological wound healing, which affects the beauty of patients, and even affects the normal physical functions of patients. |
2022-08-01 |
2023-08-14 |
Not clear |
| Zhiguo Yang, Yang Lv, Zizheng Yang, Liuliu Cao, Dongsheng Ca. Concentration-Dependent Inhibition of Hypertrophic Scar Formation by Botulinum Toxin Type A in a Rabbit Ear Model. Aesthetic plastic surgery. 2022-07-21. PMID:35864206. |
concentration-dependent inhibition of hypertrophic scar formation by botulinum toxin type a in a rabbit ear model. |
2022-07-21 |
2023-08-14 |
rabbit |
| Zhiguo Yang, Yang Lv, Zizheng Yang, Liuliu Cao, Dongsheng Ca. Concentration-Dependent Inhibition of Hypertrophic Scar Formation by Botulinum Toxin Type A in a Rabbit Ear Model. Aesthetic plastic surgery. 2022-07-21. PMID:35864206. |
hypertrophic scar (hs), as a disappointing result of wound healing, adversely affects the patient, both physically and psychologically. |
2022-07-21 |
2023-08-14 |
rabbit |
| Esteban A Molina, Brandon Hartmann, Mary A Oliver, Liam D Kirkpatrick, John W Keyloun, Lauren T Moffatt, Jeffrey W Shupp, Taryn E Travis, Bonnie C Carne. Angiogenic gene characterization and vessel permeability of dermal microvascular endothelial cells isolated from burn hypertrophic scar. Scientific reports. vol 12. issue 1. 2022-07-19. PMID:35851095. |
angiogenic gene characterization and vessel permeability of dermal microvascular endothelial cells isolated from burn hypertrophic scar. |
2022-07-19 |
2023-08-14 |
Not clear |
| Esteban A Molina, Brandon Hartmann, Mary A Oliver, Liam D Kirkpatrick, John W Keyloun, Lauren T Moffatt, Jeffrey W Shupp, Taryn E Travis, Bonnie C Carne. Angiogenic gene characterization and vessel permeability of dermal microvascular endothelial cells isolated from burn hypertrophic scar. Scientific reports. vol 12. issue 1. 2022-07-19. PMID:35851095. |
hypertrophic scar (hts) formation is a common challenge for patients after burn injury. |
2022-07-19 |
2023-08-14 |
Not clear |