| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joon Seok Lee, Gyeong Hwa Kim, Jong Ho Lee, Jeong Yeop Ryu, Eun Jung Oh, Hyun Mi Kim, Suin Kwak, Keun Hur, Ho Yun Chun. MicroRNA-365a/b-3p as a Potential Biomarker for Hypertrophic Scars. International journal of molecular sciences. vol 23. issue 11. 2022-06-10. PMID:35682793. |
however, the mechanism of hypertrophic scar (hs) formation remains unclear. |
2022-06-10 |
2023-08-14 |
mouse |
| Yunxian Dong, Dongming Lv, Zirui Zhao, Zhongye Xu, Zhicheng Hu, Bing Tan. Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis. Frontiers in bioengineering and biotechnology. vol 10. 2022-06-10. PMID:35685086. |
lycorine inhibits hypertrophic scar formation by inducing ros-mediated apoptosis. |
2022-06-10 |
2023-08-14 |
Not clear |
| David Dolivo, Adrian Rodrigues, Lauren Sun, Chun Hou, Yingxing Li, Eugene Chung, Kai Leung, Robert Galiano, Thomas Mustoe, Seok Jong Hon. Simvastatin cream alleviates dermal fibrosis in a rabbit ear hypertrophic scar model. Journal of cosmetic dermatology. 2022-06-06. PMID:35665590. |
simvastatin cream alleviates dermal fibrosis in a rabbit ear hypertrophic scar model. |
2022-06-06 |
2023-08-14 |
rabbit |
| Jing Wang, Ming Zhao, Hongyun Zhang, Fangfang Yang, Liang Luo, Kuo Shen, Xujie Wang, Yan Li, Jian Zhang, Jinxin Zhang, Kejia Wang, Jin Li, Yunwei Wang, Yunshu Yang, Dahai H. KLF4 Alleviates Hypertrophic Scar Fibrosis by Directly Activating BMP4 Transcription. International journal of biological sciences. vol 18. issue 8. 2022-05-31. PMID:35637963. |
klf4 alleviates hypertrophic scar fibrosis by directly activating bmp4 transcription. |
2022-05-31 |
2023-08-13 |
Not clear |
| Qing Zhang, Lin Shi, Hong He, Xingmou Liu, Yong Huang, Dan Xu, Mengyun Yao, Ning Zhang, Yicheng Guo, Yifei Lu, Haisheng Li, Junyi Zhou, Jianglin Tan, Malcolm Xing, Gaoxing Lu. Down-Regulating Scar Formation by Microneedles Directly ACS nano. 2022-05-26. PMID:35617518. |
down-regulating scar formation by microneedles directly excessive extracellular matrix deposition drives fibroblasts into a state of high mechanical stress, exacerbating pathological fibrosis and hypertrophic scar formation, leading to tissue dysfunction. |
2022-05-26 |
2023-08-13 |
rabbit |
| Qing Zhang, Lin Shi, Hong He, Xingmou Liu, Yong Huang, Dan Xu, Mengyun Yao, Ning Zhang, Yicheng Guo, Yifei Lu, Haisheng Li, Junyi Zhou, Jianglin Tan, Malcolm Xing, Gaoxing Lu. Down-Regulating Scar Formation by Microneedles Directly ACS nano. 2022-05-26. PMID:35617518. |
we found that by tuning the mn size and density only, the biocompatible mns significantly decreased the scar elevation index in the rabbit ear hypertrophic scar model and increased ultimate tensile strength close to regular skin. |
2022-05-26 |
2023-08-13 |
rabbit |
| C Wang, W Chen, B J Wan. [Regulatory effects and signaling mechanism of sodium ferulate on the proliferation and apoptosis of human skin hypertrophic scar fibroblasts]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 38. issue 5. 2022-05-23. PMID:35599423. |
[regulatory effects and signaling mechanism of sodium ferulate on the proliferation and apoptosis of human skin hypertrophic scar fibroblasts]. |
2022-05-23 |
2023-08-13 |
human |
| Junzheng Wu, Yajuan Song, Zhou Yu, Baoqiang Son. [Research progress of IL-10 in hypertrophic scar]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 4. 2022-05-18. PMID:35583067. |
[research progress of il-10 in hypertrophic scar]. |
2022-05-18 |
2023-08-13 |
Not clear |
| Junzheng Wu, Yajuan Song, Zhou Yu, Baoqiang Son. [Research progress of IL-10 in hypertrophic scar]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 4. 2022-05-18. PMID:35583067. |
hypertrophic scar is a common skin fibrosis disease. |
2022-05-18 |
2023-08-13 |
Not clear |
| Junzheng Wu, Yajuan Song, Zhou Yu, Baoqiang Son. [Research progress of IL-10 in hypertrophic scar]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 4. 2022-05-18. PMID:35583067. |
with the deepening understanding of immune response and related cytokines in the process of hypertrophic scar formation, the immunotherapy for hypertrophic scar is also gradually improved. |
2022-05-18 |
2023-08-13 |
Not clear |
| Junzheng Wu, Yajuan Song, Zhou Yu, Baoqiang Son. [Research progress of IL-10 in hypertrophic scar]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 4. 2022-05-18. PMID:35583067. |
interleukin 10 (il-10) is an important member of the leukocyte family, which has different expression in different cells and exerts an immunosuppressive effect mainly through regulating the activity of immune cells infiltrated in hypertrophic scar. |
2022-05-18 |
2023-08-13 |
Not clear |
| Junzheng Wu, Yajuan Song, Zhou Yu, Baoqiang Son. [Research progress of IL-10 in hypertrophic scar]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 4. 2022-05-18. PMID:35583067. |
therefore, its role in the formation of hypertrophic scar is critical for developing and improving the immunotherapy for hypertrophic scar. |
2022-05-18 |
2023-08-13 |
Not clear |
| Oluwatosin Stephen Ilori, Ayodeji O Oladele, Oluwatosin Ruth Ilori, David A Oniled. Efficacy Of Microporous Tape In The Prevention Of Abnormal Post-Surgical Scars Among A Black Population. Journal of Ayub Medical College, Abbottabad : JAMC. vol 34. issue 2. 2022-05-16. PMID:35576276. |
the conversion of normal scarring to hypertrophic scarring occurs six to eight weeks after surgery as a result of increasing scar tension. |
2022-05-16 |
2023-08-13 |
Not clear |
| D Nidhal Ghazy, A Rahmah Abu-Raghi. Effects of Apremilast on Induced Hypertrophic Scar of Rabbits. Archives of Razi Institute. vol 76. issue 6. 2022-05-13. PMID:35546978. |
effects of apremilast on induced hypertrophic scar of rabbits. |
2022-05-13 |
2023-08-13 |
rabbit |
| D Nidhal Ghazy, A Rahmah Abu-Raghi. Effects of Apremilast on Induced Hypertrophic Scar of Rabbits. Archives of Razi Institute. vol 76. issue 6. 2022-05-13. PMID:35546978. |
group i consists of apparently healthy control rabbits, in group ii, the rabbits with an induced hypertrophic scar received no treatment, except for base gel. |
2022-05-13 |
2023-08-13 |
rabbit |
| D Nidhal Ghazy, A Rahmah Abu-Raghi. Effects of Apremilast on Induced Hypertrophic Scar of Rabbits. Archives of Razi Institute. vol 76. issue 6. 2022-05-13. PMID:35546978. |
in group iii, the rabbits with induced hypertrophic scar were treated with triamcinolone acetonide (tac) 0.1% as standard medication. |
2022-05-13 |
2023-08-13 |
rabbit |
| D Nidhal Ghazy, A Rahmah Abu-Raghi. Effects of Apremilast on Induced Hypertrophic Scar of Rabbits. Archives of Razi Institute. vol 76. issue 6. 2022-05-13. PMID:35546978. |
in the treatments, the inflammatory score, scar index, as well as immunological scores of tgfβ1 and collagen iii, significantly decreased, compared to the hypertrophic induced scar group ( |
2022-05-13 |
2023-08-13 |
rabbit |
| Ignace De Decker, Henk Hoeksema, Els Vanlerberghe, Anse Beeckman, Jozef Verbelen, Petra De Coninck, Marijn M Speeckaert, Phillip Blondeel, Stan Monstrey, Karel E Y Clae. Occlusion and hydration of scars: moisturizers versus silicone gels. Burns : journal of the International Society for Burn Injuries. 2022-05-13. PMID:35550830. |
it is generally accepted that scar dehydration resulting from impaired barrier function of the stratum corneum and expressed by raised trans epidermal water loss (tewl) values, can lead to increased fibroblast activity and thereby hypertrophic scar formation. |
2022-05-13 |
2023-08-13 |
Not clear |
| Qin Guo, Ping Xu, Jianzhou Y. Observation on the efficacy of 1565-nm non-ablative fractional laser combined with compound betamethasone topical application on the treatment of early scar in Chinese patients. Lasers in medical science. 2022-04-28. PMID:35482129. |
the objective of the study was to evaluate the efficacy of combining 1565-nm non-ablative fractional laser with low-dose compound betamethasone topical application in the treatment of immature early red hypertrophic scar. |
2022-04-28 |
2023-08-13 |
Not clear |
| Qin Guo, Ping Xu, Jianzhou Y. Observation on the efficacy of 1565-nm non-ablative fractional laser combined with compound betamethasone topical application on the treatment of early scar in Chinese patients. Lasers in medical science. 2022-04-28. PMID:35482129. |
we enrolled 38 cases of patients who had immature red hypertrophic scar due to surgery or trauma which are all less than 6 months old. |
2022-04-28 |
2023-08-13 |
Not clear |