| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui Song Cui, Dong Hyun Kim, So Young Joo, Yoon Soo Cho, June-Bum Kim, Cheong Hoon Se. Exosomes derived from human hypertrophic scar fibroblasts induces smad and TAK1 signaling in normal dermal fibroblasts. Archives of biochemistry and biophysics. 2022-04-17. PMID:35430216. |
exosomes derived from human hypertrophic scar fibroblasts induces smad and tak1 signaling in normal dermal fibroblasts. |
2022-04-17 |
2023-08-13 |
human |
| Hui Song Cui, Dong Hyun Kim, So Young Joo, Yoon Soo Cho, June-Bum Kim, Cheong Hoon Se. Exosomes derived from human hypertrophic scar fibroblasts induces smad and TAK1 signaling in normal dermal fibroblasts. Archives of biochemistry and biophysics. 2022-04-17. PMID:35430216. |
however, the functional properties of exosomes derived from hypertrophic scar fibroblasts (htsfs) have not yet been studied extensively. |
2022-04-17 |
2023-08-13 |
human |
| Hui Song Cui, Dong Hyun Kim, So Young Joo, Yoon Soo Cho, June-Bum Kim, Cheong Hoon Se. Exosomes derived from human hypertrophic scar fibroblasts induces smad and TAK1 signaling in normal dermal fibroblasts. Archives of biochemistry and biophysics. 2022-04-17. PMID:35430216. |
htsfs and hnfs were isolated from human hypertrophic scar tissues. |
2022-04-17 |
2023-08-13 |
human |
| Hui Song Cui, Dong Hyun Kim, So Young Joo, Yoon Soo Cho, June-Bum Kim, Cheong Hoon Se. Exosomes derived from human hypertrophic scar fibroblasts induces smad and TAK1 signaling in normal dermal fibroblasts. Archives of biochemistry and biophysics. 2022-04-17. PMID:35430216. |
our results demonstrate the fibrotic property of htsfs-derived exosomes, which suggests a potential functional role in hypertrophic scar development and a new therapeutic target. |
2022-04-17 |
2023-08-13 |
human |
| Qifei Shang, Yanhua Yang, Hangzhu L. LINC01605 knockdown induces apoptosis in human Tenon's capsule fibroblasts by inhibiting autophagy. Experimental and therapeutic medicine. vol 23. issue 5. 2022-04-11. PMID:35401799. |
formation of a hypertrophic scar (hs) is the main cause of failure of glaucoma surgery. |
2022-04-11 |
2023-08-13 |
human |
| Mark Brewin, Sharon Docherty, Vanessa Heaslip, Katie Breheny, Jonathon Pleat, Shelley Rhodes, Paul P M van Zuijlen, Mamta Sha. Early Laser for Burn Scars (ELABS): protocol for a multi-centre randomised, controlled trial of both the effectiveness and cost-effectiveness of the treatment of hypertrophic burn scars with Pulsed Dye Laser and standard care compared to standard care alone [version 1; peer review: 2 approved]. NIHR open research. vol 2. 2022-04-08. PMID:35392303. |
the aim is to assess the effectiveness of treating hypertrophic burns scars with pulsed dye laser (pdl) at an early stage of scar formation. |
2022-04-08 |
2023-08-13 |
Not clear |
| Zachariah E Hale, Junichi Sadoshim. Primary Cilia and Their Role in Acquired Heart Disease. Cells. vol 11. issue 6. 2022-03-25. PMID:35326411. |
induced primary cilia inactivation by other mechanisms also produces excess myocardial hypertrophy and altered scar architecture after ischemic injury, as well as hypertension due to a lack of vascular endothelial nitric oxide synthase activation and the resultant left ventricular dysfunction. |
2022-03-25 |
2023-08-13 |
Not clear |
| Y B Meng, J Lei, H R Zhang, Z M Hao, P Y Bai, P Dua. [Clinical effects of in situ perforation of preserved split scar matrix in combination with scalp transplantation and vacuum sealing drainage in the treatment of hypertrophic scar in non-functional sites after burns]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 38. issue 3. 2022-03-24. PMID:35325970. |
[clinical effects of in situ perforation of preserved split scar matrix in combination with scalp transplantation and vacuum sealing drainage in the treatment of hypertrophic scar in non-functional sites after burns]. |
2022-03-24 |
2023-08-13 |
Not clear |
| Shunuo Zhang, Ke Li, Zhixi Yu, Jun Chai, Zheng Zhang, Yixin Zhang, Peiru Mi. Dramatic Effect of Botulinum Toxin Type A on Hypertrophic Scar: A Promising Therapeutic Drug and Its Mechanism Through the SP-NK1R Pathway in Cutaneous Neurogenic Inflammation. Frontiers in medicine. vol 9. 2022-03-21. PMID:35308522. |
dramatic effect of botulinum toxin type a on hypertrophic scar: a promising therapeutic drug and its mechanism through the sp-nk1r pathway in cutaneous neurogenic inflammation. |
2022-03-21 |
2023-08-13 |
Not clear |
| Shunuo Zhang, Ke Li, Zhixi Yu, Jun Chai, Zheng Zhang, Yixin Zhang, Peiru Mi. Dramatic Effect of Botulinum Toxin Type A on Hypertrophic Scar: A Promising Therapeutic Drug and Its Mechanism Through the SP-NK1R Pathway in Cutaneous Neurogenic Inflammation. Frontiers in medicine. vol 9. 2022-03-21. PMID:35308522. |
hypertrophic scar formation may be related to cutaneous neurogenic inflammation (cni) through the substance p-neurokinin 1 receptor (sp-nk1r) signaling pathway. |
2022-03-21 |
2023-08-13 |
Not clear |
| Qin Guo, Yujia Li, Yuan Chen, Jin Ji, Shizhong Zheng, Xuefen Xu, Biyun Zhang, Jianzhou Y. β-Elemene induces apoptosis by activating the P53 pathway in human hypertrophic scar fibroblasts. IUBMB life. 2022-03-16. PMID:35294085. |
β-elemene induces apoptosis by activating the p53 pathway in human hypertrophic scar fibroblasts. |
2022-03-16 |
2023-08-13 |
human |
| Qin Guo, Yujia Li, Yuan Chen, Jin Ji, Shizhong Zheng, Xuefen Xu, Biyun Zhang, Jianzhou Y. β-Elemene induces apoptosis by activating the P53 pathway in human hypertrophic scar fibroblasts. IUBMB life. 2022-03-16. PMID:35294085. |
hypertrophic scar (hs) is a condition characterized by excessive synthesis and deposition of collagen. |
2022-03-16 |
2023-08-13 |
human |
| Nan Zhang, Lingping Xue, Ayesha Younas, Fenfen Liu, Junhong Sun, Zhuolin Dong, Yongxing Zha. Co-delivery of triamcinolone acetonide and verapamil for synergistic treatment of hypertrophic scars via carboxymethyl chitosan and Bletilla striata polysaccharide-based microneedles. Carbohydrate polymers. vol 284. 2022-03-15. PMID:35287918. |
hypertrophic scar (hs) is a frequently diagnosed skin disease that is difficult to treat. |
2022-03-15 |
2023-08-13 |
Not clear |
| Darren B Abbas, Hendrik Lintel, Michelle Griffin, Nicholas J Guardino, Jason L Guo, Amanda F Spielman, Asha C Cotterell, Jennifer B L Parker, Michael Januszyk, Derrick C Wa. Tension offloading improves cutaneous scar formation in Achilles tendon repair. Journal of surgical case reports. vol 2022. issue 3. 2022-03-14. PMID:35280050. |
hypertrophic scar formation and non-healing wounds following achilles tendon repair arise from poor vascularity to the incisional site or from excess mechanical stress/strain to the incision during the healing process. |
2022-03-14 |
2023-08-13 |
Not clear |
| Darren B Abbas, Hendrik Lintel, Michelle Griffin, Nicholas J Guardino, Jason L Guo, Amanda F Spielman, Asha C Cotterell, Jennifer B L Parker, Michael Januszyk, Derrick C Wa. Tension offloading improves cutaneous scar formation in Achilles tendon repair. Journal of surgical case reports. vol 2022. issue 3. 2022-03-14. PMID:35280050. |
by pod 120, the untreated portion of the achilles incision appeared hypertrophic and hyperpigmented, while the treated portion of the scar appeared flat with minimal pigmentation changes. |
2022-03-14 |
2023-08-13 |
Not clear |
| Martin Direder, Tamara Weiss, Dragan Copic, Vera Vorstandlechner, Maria Laggner, Karin Pfisterer, Caterina Selina Mildner, Katharina Klas, Daniel Bormann, Werner Haslik, Christine Radtke, Matthias Farlik, Lisa Shaw, Bahar Golabi, Erwin Tschachler, Konrad Hoetzenecker, Hendrik Jan Ankersmit, Michael Mildne. Schwann cells contribute to keloid formation. Matrix biology : journal of the International Society for Matrix Biology. 2022-03-12. PMID:35278628. |
here we analyzed the characteristics of keloidal cells by single cell sequencing and discovered the presence of an abundant population of schwann cells that persisted in the hypertrophic scar tissue after wound healing. |
2022-03-12 |
2023-08-13 |
Not clear |
| Xiaojing Ge, Yute Sun, Youzhi Tang, Jing Lin, Fang Zhou, Gang Yao, Xin S. Circular RNA HECTD1 knockdown inhibits transforming growth factor-beta/ small mothers against decapentaplegic (TGF-β/Smad) signaling to reduce hypertrophic scar fibrosis. Bioengineered. vol 13. issue 3. 2022-03-05. PMID:35246019. |
circular rna hectd1 knockdown inhibits transforming growth factor-beta/ small mothers against decapentaplegic (tgf-β/smad) signaling to reduce hypertrophic scar fibrosis. |
2022-03-05 |
2023-08-13 |
human |
| Xiaojing Ge, Yute Sun, Youzhi Tang, Jing Lin, Fang Zhou, Gang Yao, Xin S. Circular RNA HECTD1 knockdown inhibits transforming growth factor-beta/ small mothers against decapentaplegic (TGF-β/Smad) signaling to reduce hypertrophic scar fibrosis. Bioengineered. vol 13. issue 3. 2022-03-05. PMID:35246019. |
circhectd1 is highly expressed in hs tissues and human skin hypertrophic scar fibroblasts (hsf); its loss of function inhibits cell proliferation, migration, invasion, fibrosis, and tgf-β/smad signaling. |
2022-03-05 |
2023-08-13 |
human |
| Catherine R Tuckey, Susan H Kohut, Dale W Edga. Case study: Pilot testing of a local acupuncture intervention protocol for burn scars. Scars, burns & healing. vol 8. 2022-02-28. PMID:35223089. |
following burn injury and a prolonged duration of healing, scars may become hypertrophic, causing movement restriction, increased scar thickness, colour and pliability, and symptoms such as pain and itch. |
2022-02-28 |
2023-08-13 |
Not clear |
| Ebube Ob. Surgical Considerations In Skin of Colour. Clinical and experimental dermatology. 2022-02-21. PMID:35187688. |
many years later mancini (in 1962) and peacock (in 1970) classified excessive scarring into hypertrophic and keloid scar formation. |
2022-02-21 |
2023-08-13 |
Not clear |