| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bin Zhao, Xueqin Shi, Dengchao Feng, Juntao Han, Dahai H. MicroRNA let-7d attenuates hypertrophic scar fibrosis through modulation of iron metabolism by reducing DMT1 expression. Journal of molecular histology. 2023-01-27. PMID:36705783. |
microrna let-7d attenuates hypertrophic scar fibrosis through modulation of iron metabolism by reducing dmt1 expression. |
2023-01-27 |
2023-08-14 |
human |
| Bin Zhao, Xueqin Shi, Dengchao Feng, Juntao Han, Dahai H. MicroRNA let-7d attenuates hypertrophic scar fibrosis through modulation of iron metabolism by reducing DMT1 expression. Journal of molecular histology. 2023-01-27. PMID:36705783. |
hypertrophic scar is an unavoidable result of wound healing following burns and trauma, which remains a challenging problem for clinicians. |
2023-01-27 |
2023-08-14 |
human |
| Bin Zhao, Xueqin Shi, Dengchao Feng, Juntao Han, Dahai H. MicroRNA let-7d attenuates hypertrophic scar fibrosis through modulation of iron metabolism by reducing DMT1 expression. Journal of molecular histology. 2023-01-27. PMID:36705783. |
consistent with the results in vitro, the mir-let-7d mimics effectively ameliorated hypertrophic scar fibrosis in a rabbit ear hypertrophic scar model. |
2023-01-27 |
2023-08-14 |
human |
| Bin Zhao, Xueqin Shi, Dengchao Feng, Juntao Han, Dahai H. MicroRNA let-7d attenuates hypertrophic scar fibrosis through modulation of iron metabolism by reducing DMT1 expression. Journal of molecular histology. 2023-01-27. PMID:36705783. |
taken together, our results indicated for the first time that mir-let-7d attenuated hypertrophic scar fibrosis through modulation of iron metabolism by reducing iron uptake through dmt1, which may provide a novel therapeutic strategy for hypertrophic scar. |
2023-01-27 |
2023-08-14 |
human |
| Yiman Chen, Huihui Deng, Liya Yang, Ling Guo, Min Fen. Desferrioxamine enhances 5-aminolaevulinic acid- induced protoporphyrin IX accumulation and therapeutic efficacy for hypertrophic scar. Journal of pharmaceutical sciences. 2023-01-22. PMID:36682488. |
desferrioxamine enhances 5-aminolaevulinic acid- induced protoporphyrin ix accumulation and therapeutic efficacy for hypertrophic scar. |
2023-01-22 |
2023-08-14 |
Not clear |
| Yiman Chen, Huihui Deng, Liya Yang, Ling Guo, Min Fen. Desferrioxamine enhances 5-aminolaevulinic acid- induced protoporphyrin IX accumulation and therapeutic efficacy for hypertrophic scar. Journal of pharmaceutical sciences. 2023-01-22. PMID:36682488. |
hypertrophic scar is a common problem after skin burns or trauma which brings physical, psychological, and cosmetic problems to patients. |
2023-01-22 |
2023-08-14 |
Not clear |
| Yiman Chen, Huihui Deng, Liya Yang, Ling Guo, Min Fen. Desferrioxamine enhances 5-aminolaevulinic acid- induced protoporphyrin IX accumulation and therapeutic efficacy for hypertrophic scar. Journal of pharmaceutical sciences. 2023-01-22. PMID:36682488. |
photodynamic therapy with 5-aminolevulinic acid (5-ala) is a promising therapy for hypertrophic scar. |
2023-01-22 |
2023-08-14 |
Not clear |
| Yiman Chen, Huihui Deng, Liya Yang, Ling Guo, Min Fen. Desferrioxamine enhances 5-aminolaevulinic acid- induced protoporphyrin IX accumulation and therapeutic efficacy for hypertrophic scar. Journal of pharmaceutical sciences. 2023-01-22. PMID:36682488. |
herein, a mixture of 5-ala and dfo (deferoxamine, a special iron chelator) was applied for the treatment of hypertrophic scar. |
2023-01-22 |
2023-08-14 |
Not clear |
| Yiman Chen, Huihui Deng, Liya Yang, Ling Guo, Min Fen. Desferrioxamine enhances 5-aminolaevulinic acid- induced protoporphyrin IX accumulation and therapeutic efficacy for hypertrophic scar. Journal of pharmaceutical sciences. 2023-01-22. PMID:36682488. |
in addition, injection locally into the lesion was applied, which combined with enhanced photodynamic therapy to destroy hypertrophic scar fibroblasts. |
2023-01-22 |
2023-08-14 |
Not clear |
| Yiman Chen, Huihui Deng, Liya Yang, Ling Guo, Min Fen. Desferrioxamine enhances 5-aminolaevulinic acid- induced protoporphyrin IX accumulation and therapeutic efficacy for hypertrophic scar. Journal of pharmaceutical sciences. 2023-01-22. PMID:36682488. |
in vitro experiments showed that 5-ala/dfo could increase more ros generation by increasing the accumulation of ppix, resulting in the apoptosis of hypertrophic scar fibroblasts. |
2023-01-22 |
2023-08-14 |
Not clear |
| Yiman Chen, Huihui Deng, Liya Yang, Ling Guo, Min Fen. Desferrioxamine enhances 5-aminolaevulinic acid- induced protoporphyrin IX accumulation and therapeutic efficacy for hypertrophic scar. Journal of pharmaceutical sciences. 2023-01-22. PMID:36682488. |
furthermore, 5-ala/dfo inhibited the proliferation and migration of hypertrophic scar fibroblasts. |
2023-01-22 |
2023-08-14 |
Not clear |
| Yiman Chen, Huihui Deng, Liya Yang, Ling Guo, Min Fen. Desferrioxamine enhances 5-aminolaevulinic acid- induced protoporphyrin IX accumulation and therapeutic efficacy for hypertrophic scar. Journal of pharmaceutical sciences. 2023-01-22. PMID:36682488. |
therefore, 5-ala/dfo has the potential to enhance the photodynamic therapy of 5-ala and provides a new treatment strategy for hypertrophic scar. |
2023-01-22 |
2023-08-14 |
Not clear |
| Fabio Stefano Frech, Loren Hernandez, Rebecca Urbonas, Ghufran Abo Zaken, Isabella Dreyfuss, Keyvan Nour. Hypertrophic Scars and Keloids: Advances in Treatment and Review of Established Therapies. American journal of clinical dermatology. 2023-01-20. PMID:36662366. |
still, keloid and hypertrophic scar therapies are widely diverse with novel treatment modalities providing alternatives for recurring lesions. |
2023-01-20 |
2023-08-14 |
Not clear |
| Yihui Huang, Jingwen Li, Yan Wang, Danyang Chen, Jianglong Huang, Wubin Dai, Pan Peng, Liang Guo, Yifeng Le. Intradermal delivery of an angiotensin II receptor blocker using a personalized microneedle patch for treatment of hypertrophic scars. Biomaterials science. vol 11. issue 2. 2023-01-17. PMID:36475528. |
high-quality postoperative rehabilitation is the focus of most patients currently, and hypertrophic scar (hs) greatly reduces the patient's quality of life due to the symptom of severe itching. |
2023-01-17 |
2023-08-14 |
rabbit |
| Yihui Huang, Jingwen Li, Yan Wang, Danyang Chen, Jianglong Huang, Wubin Dai, Pan Peng, Liang Guo, Yifeng Le. Intradermal delivery of an angiotensin II receptor blocker using a personalized microneedle patch for treatment of hypertrophic scars. Biomaterials science. vol 11. issue 2. 2023-01-17. PMID:36475528. |
losartan, as a drug class of angiotensin ii receptor blockers (arbs), can effectively inhibit the proliferation and migration of hypertrophic scar fibroblasts (hsfs) and downregulate the gene expression related to scar formation in hsfs. |
2023-01-17 |
2023-08-14 |
rabbit |
| Sebastian P Nischwitz, Julia Fink, Marlies Schellnegger, Hanna Luze, Vladimir Bubalo, Carolin Tetyczka, Eva Roblegg, Christian Holecek, Martin Zacharias, Lars-Peter Kamolz, Petra Kotzbec. The Role of Local Inflammation and Hypoxia in the Formation of Hypertrophic Scars-A New Model in the Duroc Pig. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36613761. |
the goal of this project was to investigate the mechanisms of scar formation after prolonged wound inflammation and to introduce a method for generating standardized hypertrophic scars by inducing prolonged inflammation. |
2023-01-08 |
2023-08-14 |
Not clear |
| Yajuan Song, Tong Wang, Liu Yang, Junzheng Wu, Lin Chen, Xiao Fan, Zhe Zhang, Qing Yang, Zhou Yu, Baoqiang Son. EGCG inhibits hypertrophic scar formation in a rabbit ear model. Journal of cosmetic dermatology. 2023-01-06. PMID:36606405. |
egcg inhibits hypertrophic scar formation in a rabbit ear model. |
2023-01-06 |
2023-08-14 |
mouse |
| Yajuan Song, Tong Wang, Liu Yang, Junzheng Wu, Lin Chen, Xiao Fan, Zhe Zhang, Qing Yang, Zhou Yu, Baoqiang Son. EGCG inhibits hypertrophic scar formation in a rabbit ear model. Journal of cosmetic dermatology. 2023-01-06. PMID:36606405. |
in the present study, the therapeutic effects of egcg on hypertrophic scar were analyzed using a rabbit ear hypertrophic scar model. |
2023-01-06 |
2023-08-14 |
mouse |
| C H Song, J B Li, W Lan, S Q Chen, Y Z Liu, X L Ji, X F Yi, T B Lin, Tianbao Su. [Effects and mechanism of pressure treatment on hemodynamic changes in patients with hypertrophic scar secondary to extensive burns]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 38. issue 12. 2023-01-03. PMID:36594142. |
[effects and mechanism of pressure treatment on hemodynamic changes in patients with hypertrophic scar secondary to extensive burns]. |
2023-01-03 |
2023-08-14 |
Not clear |
| L L Shi, M Z Liu, Z Y Jiang, X T Yu, J Q Li, G H Gu. [Research advances on pharmacological interventions for hypertrophic scar]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 38. issue 12. 2023-01-03. PMID:36594149. |
[research advances on pharmacological interventions for hypertrophic scar]. |
2023-01-03 |
2023-08-14 |
Not clear |