| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Darlene A Mitrano, Kelsey Jackson, Samantha Finley, Allison Seele. α1b-Adrenergic Receptor Localization and Relationship to the D1-Dopamine Receptor in the Rat Nucleus Accumbens. Neuroscience. vol 371. 2018-12-11. PMID:29229557. |
therefore, using immunohistochemistry and electron microscopy techniques, this study describes the subcellular localization of the α1b-adrenergic receptor (α1bar), the subtype most tied to relapse behaviors, as well as its relationship to the d1-dopamine receptor (d1r) in both the shell and core of the rat nucleus accumbens (nac). |
2018-12-11 |
2023-08-13 |
rat |
| Xixi Zhao, Ru Yang, Kewan Wang, Zhongping Zhang, Junling Wang, Xiangliang Tan, Jiajun Zhang, Yingjie Mei, Queenie Chan, Jun Xu, Qianjin Feng, Yikai X. Connectivity-based parcellation of the nucleus accumbens into core and shell portions for stereotactic target localization and alterations in each NAc subdivision in mTLE patients. Human brain mapping. vol 39. issue 3. 2018-12-11. PMID:29266652. |
connectivity-based parcellation of the nucleus accumbens into core and shell portions for stereotactic target localization and alterations in each nac subdivision in mtle patients. |
2018-12-11 |
2023-08-13 |
Not clear |
| Xixi Zhao, Ru Yang, Kewan Wang, Zhongping Zhang, Junling Wang, Xiangliang Tan, Jiajun Zhang, Yingjie Mei, Queenie Chan, Jun Xu, Qianjin Feng, Yikai X. Connectivity-based parcellation of the nucleus accumbens into core and shell portions for stereotactic target localization and alterations in each NAc subdivision in mTLE patients. Human brain mapping. vol 39. issue 3. 2018-12-11. PMID:29266652. |
the nucleus accumbens (nac), an important target of deep brain stimulation for some neuropsychiatric disorders, is thought to be involved in epileptogenesis, especially the shell portion. |
2018-12-11 |
2023-08-13 |
Not clear |
| Zahra Fatahi, Abbas Haghparas. Activation of the cannabinoid system in the nucleus accumbens affects effort-based decision making. Pharmacology, biochemistry, and behavior. vol 165. 2018-12-11. PMID:29291421. |
the nucleus accumbens (nac) is implicated in allowing an animal to overcome effort constraints to obtain greater benefits, and it has been previously shown that cannabis derivatives may affect such processes. |
2018-12-11 |
2023-08-13 |
rat |
| Zachary S Lorsch, Yong-Hwee Eddie Loh, Immanuel Purushothaman, Deena M Walker, Eric M Parise, Marine Salery, Michael E Cahill, Georgia E Hodes, Madeline L Pfau, Hope Kronman, Peter J Hamilton, Orna Issler, Benoit Labonté, Ann E Symonds, Matthew Zucker, Tie Yuan Zhang, Michael J Meaney, Scott J Russo, Li Shen, Rosemary C Bagot, Eric J Nestle. Estrogen receptor α drives pro-resilient transcription in mouse models of depression. Nature communications. vol 9. issue 1. 2018-12-11. PMID:29549264. |
we identify estrogen receptor α (erα) as the top regulator of pro-resilient transcriptional changes in the nucleus accumbens (nac), a key brain reward region implicated in depression. |
2018-12-11 |
2023-08-13 |
mouse |
| Yan-Jia Luo, Ya-Dong Li, Lu Wang, Su-Rong Yang, Xiang-Shan Yuan, Juan Wang, Yoan Cherasse, Michael Lazarus, Jiang-Fan Chen, Wei-Min Qu, Zhi-Li Huan. Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D Nature communications. vol 9. issue 1. 2018-12-11. PMID:29679009. |
nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine d nucleus accumbens (nac) is involved in behaviors that depend on heightened wakefulness, but its impact on arousal remains unclear. |
2018-12-11 |
2023-08-13 |
Not clear |
| Rachel-Karson Thériault, Francesco Leri, Bettina Kalisc. The role of neuronal nitric oxide synthase in cocaine place preference and mu opioid receptor expression in the nucleus accumbens. Psychopharmacology. vol 235. issue 9. 2018-12-11. PMID:29992335. |
there is evidence that central mu opioid receptors (mors) are implicated in several aspects of cocaine addiction, and that mor expression is elevated by cocaine in vitro and in the nucleus accumbens (nac) when administered in vivo. |
2018-12-11 |
2023-08-13 |
Not clear |
| Yu-Hua Tian, Shi-Xun Ma, Kwang-Wook Lee, Sunmee Wee, George F Koob, Seok-Yong Lee, Choon-Gon Jan. Blockade of TRPV1 Inhibits Methamphetamine-induced Rewarding Effects. Scientific reports. vol 8. issue 1. 2018-11-27. PMID:29343767. |
recent studies have identified the distribution of trpv1 in several brain regions that are related to drug addiction, including nucleus accumbens (nac) and dorsal striatum (dst). |
2018-11-27 |
2023-08-13 |
mouse |
| Michael J Caruso, Nicole A Crowley, Dana E Reiss, Jasmine I Caulfield, Bernhard Luscher, Sonia A Cavigelli, Helen M Kamen. Adolescent Social Stress Increases Anxiety-like Behavior and Alters Synaptic Transmission, Without Influencing Nicotine Responses, in a Sex-Dependent Manner. Neuroscience. vol 373. 2018-11-26. PMID:29343455. |
finally, we assessed prefrontal cortex (pfc) and nucleus accumbens (nac) synaptic transmission (pnd 64-80); brain regions that are implicated in anxiety and addiction. |
2018-11-26 |
2023-08-13 |
mouse |
| Raúl López-Arnau, Mario Buenrostro-Jáuregui, Jorge Camarasa, David Pubill, Elena Escubed. Effect of the combination of mephedrone plus ethanol on serotonin and dopamine release in the nucleus accumbens and medial prefrontal cortex of awake rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 3. 2018-11-26. PMID:29349706. |
in the present study, we investigated the combined effects of meph plus ethanol (etoh) on neurotransmitter release in the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc). |
2018-11-26 |
2023-08-13 |
rat |
| Joyce T Da Silva, Youping Zhang, Jamila Asgar, Jin Y Ro, David A Seminowic. Diffuse noxious inhibitory controls and brain networks are modulated in a testosterone-dependent manner in Sprague Dawley rats. Behavioural brain research. vol 349. 2018-11-26. PMID:29733874. |
rsfmri scans were acquired before and after capsaicin injection to analyze the effects of dnic on periaqueductal gray (pag), anterior cingulate cortex (acc) and nucleus accumbens (nac) connectivity to the whole brain. |
2018-11-26 |
2023-08-13 |
rat |
| Rifka C Derman, Carrie R Ferrari. Enhanced incentive motivation in obesity-prone rats is mediated by NAc core CP-AMPARs. Neuropharmacology. vol 131. 2018-11-19. PMID:29291424. |
the nucleus accumbens (nac) mediates cue-triggered reward seeking and activity in the nac is enhanced in obesity-susceptible populations. |
2018-11-19 |
2023-08-13 |
human |
| Shi-Yu Peng, Bin Li, Kang Xi, Jian-Jun Wang, Jing-Ning Zh. Presynaptic α Neuroscience letters. vol 665. 2018-11-15. PMID:29195907. |
presynaptic α the nucleus accumbens (nac), integrating information from the prefrontal cortex and limbic structures, plays a critical role in reward and emotion regulation. |
2018-11-15 |
2023-08-13 |
Not clear |
| Yanjiong Chen, Cuo Yang, Li Zhu, Jiaqi Li, Fanglin Guan, Teng Che. Depletion of D3 dopamine receptor affects methamphetamine-induced expression patterns of Pde4b and Atf3. Neuroscience letters. vol 665. 2018-11-13. PMID:29175029. |
here, we measured changes in pde4b and atf3 in the camp signaling pathway of dopaminergic system components, including the nucleus accumbens (nac), caudate putamen (cpu) and hippocampus (hip), in d3r knockout mice(d3r-/-) 1h and 24h after meth-induced behavioral sensitization. |
2018-11-13 |
2023-08-13 |
mouse |
| Anna E Ingebretson, Matthew C Hearing, Ethan D Huffington, Mark J Thoma. Endogenous dopamine and endocannabinoid signaling mediate cocaine-induced reversal of AMPAR synaptic potentiation in the nucleus accumbens shell. Neuropharmacology. vol 131. 2018-11-13. PMID:29225042. |
during a 10-14 day period of abstinence from cocaine, ampar signaling is potentiated at synapses on nucleus accumbens (nac) medium spiny neurons (msns), promoting a state of heightened synaptic excitability. |
2018-11-13 |
2023-08-13 |
Not clear |
| Ashlie N Reker, Alfredo Oliveros, John M Sullivan, Lailun Nahar, David J Hinton, Taehyun Kim, Robert C Bruner, Doo-Sup Choi, Nicholas E Goeders, Hyung W Na. Neurogranin in the nucleus accumbens regulates NMDA receptor tolerance and motivation for ethanol seeking. Neuropharmacology. vol 131. 2018-11-13. PMID:29225043. |
dysfunction of n-methyl-d-aspartate receptor (nmdar) signaling in the nucleus accumbens (nac) has been implicated in the pathophysiology of alcohol use disorders (aud). |
2018-11-13 |
2023-08-13 |
Not clear |
| Annalisa Nobili, Emanuele Claudio Latagliata, Maria Teresa Viscomi, Virve Cavallucci, Debora Cutuli, Giacomo Giacovazzo, Paraskevi Krashia, Francesca Romana Rizzo, Ramona Marino, Mauro Federici, Paola De Bartolo, Daniela Aversa, Maria Concetta Dell'Acqua, Alberto Cordella, Marco Sancandi, Flavio Keller, Laura Petrosini, Stefano Puglisi-Allegra, Nicola Biagio Mercuri, Roberto Coccurello, Nicola Berretta, Marcello D'Ameli. Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease. Nature communications. vol 8. 2018-11-09. PMID:28367951. |
the selective vta daergic neuron degeneration results in lower da outflow in the hippocampus and nucleus accumbens (nac) shell. |
2018-11-09 |
2023-08-13 |
mouse |
| Zi-Jun Wang, Jennifer A Martin, Amy M Gancarz, Danielle N Adank, Fraser J Sim, David M Diet. Activin A is increased in the nucleus accumbens following a cocaine binge. Scientific reports. vol 7. 2018-11-08. PMID:28272550. |
drug addiction is a long-lasting disease characterized by compulsive drug intake mediated in part by neuronal and biological adaptations in key brain areas, such as the nucleus accumbens (nac). |
2018-11-08 |
2023-08-13 |
Not clear |
| Jeremy S Lum, Bo Pan, Chao Deng, Xu-Feng Huang, Lezanne Ooi, Kelly A Newel. Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol. Psychiatry research. vol 260. 2018-11-05. PMID:29195167. |
group 1 metabotropic glutamate receptors (mglurs) and their endogenous modulators, norbin and homer1, are regulated by d2 receptor activity, particularly within the nucleus accumbens (nac), a target region of aripiprazole and haloperidol. |
2018-11-05 |
2023-08-13 |
rat |
| Jiaojiao Song, Ming Chen, Yi Dong, Bin Lai, Ping Zhen. Chronic morphine selectively sensitizes the effect of D1 receptor agonist on presynaptic glutamate release in basolateral amygdala neurons that project to prelimbic cortex. Neuropharmacology. vol 133. 2018-11-05. PMID:29427651. |
using retrogradely labelling technique combined with whole-cell patch-clamp methods, our results showed that (1) chronic morphine sensitized the effect of d1 receptor agonist on presynaptic glutamate release in bla neurons that projected to the prelimbic cortex (prl), but had no influence on that in bla neurons that projected to the nucleus accumbens (nac) or the ca1 of the hippocampus; (2) chronic morphine sensitized the effect of d1 receptor agonist on action potential firing in bla neurons that projected to the prl, but without affecting the intrinsic excitability and the sensitivity of postsynaptic glutamate receptors to glutamate in bla neurons that projected to the prl. |
2018-11-05 |
2023-08-13 |
Not clear |