| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Subramaniam Jayanthi, Betina Gonzalez, Michael T McCoy, Bruce Ladenheim, Veronica Bisagno, Jean Lud Cade. Methamphetamine Induces TET1- and TET3-Dependent DNA Hydroxymethylation of Crh and Avp Genes in the Rat Nucleus Accumbens. Molecular neurobiology. vol 55. issue 6. 2019-02-04. PMID:28842817. |
here, we show that meth administration produced time-dependent increases in the expression of corticotropin-releasing hormone (crh/crf), arginine vasopressin (avp), and cocaine- and amphetamine-regulated transcript prepropeptide (cartpt) mrnas in the rat nucleus accumbens (nac). |
2019-02-04 |
2023-08-13 |
rat |
| Ju-Ping Li, Peng Liu, Gang Lei, Zheng Chu, Fei Liu, Chao-Feng Shi, Yong-Hui Dang, Teng Che. The Role of HINT1 in Methamphetamine-Induced Conditioned Place Preference. Neurotoxicity research. vol 33. issue 2. 2019-01-31. PMID:28844119. |
in our present study, we used different batches of mice to establish the different stages of methamphetamine (meth)-induced conditioned place preference (cpp) to explore the dynamic changes throughout the process of addiction in different brain regions, including prefrontal cortex (pfc), nucleus accumbens (nac), corpus striatum (cpu), and hippocampus (hip). |
2019-01-31 |
2023-08-13 |
mouse |
| J J Dimatelis, A Mtintsilana, V Naidoo, D J Stein, V A Russel. Chronic light exposure alters serotonergic and orexinergic systems in the rat brain and reverses maternal separation-induced increase in orexin receptors in the prefrontal cortex. Metabolic brain disease. vol 33. issue 2. 2019-01-31. PMID:29039077. |
at p80, rats were decapitated and brain tissue collected for analysis of glutamate- and potassium-stimulated dopamine release in the nucleus accumbens (nac) using an in vitro superfusion technique. |
2019-01-31 |
2023-08-13 |
rat |
| Iman Shafiei, Mahsaneh Vatankhah, Leila Zarepour, Somayeh Ezzatpanah, Abbas Haghparas. Role of D1- and D2-like dopaminergic receptors in the nucleus accumbens in modulation of formalin-induced orofacial pain: Involvement of lateral hypothalamus. Physiology & behavior. vol 188. 2019-01-31. PMID:29421337. |
the present study aims to investigate the role of dopaminergic receptors in the nucleus accumbens (nac) in modulation of nociceptive responses induced by formalin injection in the orofacial region. |
2019-01-31 |
2023-08-13 |
rat |
| Yusuf S Althobaiti, Fahad S Alshehri, Alqassem Y Hakami, Alaa M Hammad, Youssef Sar. Effects of Clavulanic Acid Treatment on Reinstatement to Methamphetamine, Glial Glutamate Transporters, and mGluR 2/3 Expression in P Rats Exposed to Ethanol. Journal of molecular neuroscience : MN. vol 67. issue 1. 2019-01-31. PMID:30471010. |
in addition, we examined the expression of glt-1, xct, and glast as well as metabotropic glutamate receptor (mglur2/3) in the nucleus accumbens (nac) shell, nac core, and dorsomedial prefrontal cortex (dmpfc). |
2019-01-31 |
2023-08-13 |
rat |
| Jimmie M Gmaz, James E Carmichael, Matthijs Aa van der Mee. Persistent coding of outcome-predictive cue features in the rat nucleus accumbens. eLife. vol 7. 2019-01-29. PMID:30234485. |
the nucleus accumbens (nac) is important for learning from feedback, and for biasing and invigorating behaviour in response to cues that predict motivationally relevant outcomes. |
2019-01-29 |
2023-08-13 |
rat |
| Daniel F Hill, Kate L Parent, Christopher W Atcherley, Stephen L Cowen, Michael L Heie. Differential release of dopamine in the nucleus accumbens evoked by low-versus high-frequency medial prefrontal cortex stimulation. Brain stimulation. vol 11. issue 2. 2019-01-28. PMID:29239776. |
the medial prefrontal cortex (mpfc) coordinates goal-directed behaviors, which may be mediated through mpfc regulation of dopamine release in the nucleus accumbens (nac). |
2019-01-28 |
2023-08-13 |
Not clear |
| Takatoshi Hikida, Tom MacPherson, Makiko Morit. [Basal Ganglia Circuit Mechanisms in Cognitive Learning]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 37. issue 2. 2019-01-28. PMID:30489042. |
the nucleus accumbens (nac), the ventral part of the striatum, plays a critical role in motivation, learning, and cognition in the basal ganglia circuit. |
2019-01-28 |
2023-08-13 |
Not clear |
| Katherine N Wright, Amanda M Dossat, Caroline E Strong, Lindsay L Sailer, Samantha M Pavlock, Mohamed Kabba. Optogenetic inhibition of medial prefrontal cortex projections to the nucleus accumbens core and methyl supplementation via L-Methionine attenuates cocaine-primed reinstatement. Integrative zoology. vol 13. issue 6. 2019-01-18. PMID:30318755. |
indeed, the medial prefrontal cortex (mpfc) projections to the nucleus accumbens (nac) are critically important for reinstated cocaine-seeking in a rodent model of cocaine relapse. |
2019-01-18 |
2023-08-13 |
rat |
| Ashley M Kopec, Caroline J Smith, Nathan R Ayre, Sean C Sweat, Staci D Bilb. Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats. Nature communications. vol 9. issue 1. 2019-01-16. PMID:30254300. |
adolescence is a developmental period in which the mesolimbic dopaminergic "reward" circuitry of the brain, including the nucleus accumbens (nac), undergoes significant plasticity. |
2019-01-16 |
2023-08-13 |
rat |
| Carina Soares-Cunha, Bárbara Coimbra, Ana Verónica Domingues, Nivaldo Vasconcelos, Nuno Sousa, Ana João Rodrigue. Nucleus Accumbens Microcircuit Underlying D2-MSN-Driven Increase in Motivation. eNeuro. vol 5. issue 2. 2019-01-11. PMID:29780881. |
the nucleus accumbens (nac) plays a central role in reinforcement and motivation. |
2019-01-11 |
2023-08-13 |
Not clear |
| David Ottenheimer, Jocelyn M Richard, Patricia H Jana. Ventral pallidum encodes relative reward value earlier and more robustly than nucleus accumbens. Nature communications. vol 9. issue 1. 2019-01-08. PMID:30341305. |
the ventral striatopallidal system, a basal ganglia network thought to convert limbic information into behavioral action, includes the nucleus accumbens (nac) and the ventral pallidum (vp), typically described as a major output of nac. |
2019-01-08 |
2023-08-13 |
rat |
| Caroline J W Smith, Kevin B Wilkins, Sara Li, Maxwell T Tulimieri, Alexa H Veenem. Nucleus accumbens mu opioid receptors regulate context-specific social preferences in the juvenile rat. Psychoneuroendocrinology. vol 89. 2018-12-31. PMID:29331800. |
the μ opioid receptor (mor) in the nucleus accumbens (nac) is involved in assigning pleasurable, or hedonic value to rewarding stimuli. |
2018-12-31 |
2023-08-13 |
rat |
| Taichi Onishi, Hirokazu Sakamoto, Shigeyuki Namiki, Kenzo Hiros. The Altered Supramolecular Structure of Dopamine D2 Receptors in Disc1-deficient Mice. Scientific reports. vol 8. issue 1. 2018-12-18. PMID:29374282. |
we found that d2rs in the nucleus accumbens (nac) of wild-type mice form nanoclusters (~ 20,000 nm |
2018-12-18 |
2023-08-13 |
mouse |
| M H Lehner, K Karas-Ruszczyk, A Zakrzewska, M Gryz, A Wislowska-Stanek, K Kolosowska, N Chmielewska, A Skorzewska, D Turzynska, A Sobolewska, P Mierzejewski, A Plazni. Chronic stress changes prepulse inhibition after amphetamine challenge: the role of the dopaminergic system. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 69. issue 3. 2018-12-18. PMID:30342432. |
it was found that the initially strong response to amphetamine in the control rats was weakened after stress on both the behavioural and biochemical levels: improved ppi, decreased dopamine d2 receptor expression in the central nucleus of amygdala (cea) and nucleus accumbens (nac), and decreased dopamine and 3-mt (3-methoxytyramine) levels in nac. |
2018-12-18 |
2023-08-13 |
rat |
| Daniel W Bloodgood, Jonathan A Sugam, Andrew Holmes, Thomas L Kas. Fear extinction requires infralimbic cortex projections to the basolateral amygdala. Translational psychiatry. vol 8. issue 1. 2018-12-12. PMID:29507292. |
however, it is unclear whether these pathways are exclusively involved in extinction, or whether other major targets of the il, such as the nucleus accumbens (nac) also play a role. |
2018-12-12 |
2023-08-13 |
mouse |
| Eduardo F Gallo, Jozsef Meszaros, Jeremy D Sherman, Muhammad O Chohan, Eric Teboul, Claire S Choi, Holly Moore, Jonathan A Javitch, Christoph Kellendon. Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum. Nature communications. vol 9. issue 1. 2018-12-12. PMID:29540712. |
dopamine d2 receptors (d2rs) in the nucleus accumbens (nac) regulate motivated behavior, but the underlying neurobiological mechanisms remain unresolved. |
2018-12-12 |
2023-08-13 |
Not clear |
| Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestle. Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine. Nature communications. vol 9. issue 1. 2018-12-12. PMID:30089879. |
the role of somatostatin interneurons in nucleus accumbens (nac), a key brain reward region, remains poorly understood due to the fact that these cells account for < 1% of nac neurons. |
2018-12-12 |
2023-08-13 |
Not clear |
| H Schoch, M Y Huerta, C M Ruiz, M R Farrell, K M Jung, J J Huang, R R Campbell, D Piomelli, S V Mahle. Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats. Psychopharmacology. vol 235. issue 1. 2018-12-11. PMID:29022083. |
as a result, adolescent cannabinoid receptor stimulation (acrs) with phytocannabinoids or synthetic agonists like "spice" cause robust and persistent changes in both behavior and circuit architecture in rodents, including in reward-related regions like medial prefrontal cortex and nucleus accumbens (nac). |
2018-12-11 |
2023-08-13 |
rat |
| Yadi Li, Wenhua Zhou, Haibo Dong, Wenwen Shen, Jianbing Zhang, Feng Li, Lingjun Zhan. Lower Fractional Anisotropy in the Gray Matter of Amygdala-Hippocampus-Nucleus Accumbens Circuit in Methamphetamine Users: an In Vivo Diffusion Tensor Imaging Study. Neurotoxicity research. vol 33. issue 4. 2018-12-11. PMID:29038922. |
the basolateral amygdala (bla), hippocampal ventral subiculum, and nucleus accumbens (nac) comprise the amygdala-hippocampus-nac (ahn) circuit, which is implicated in drug seeking and reward. |
2018-12-11 |
2023-08-13 |
human |