| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Aaron Bola, Eugene A Kiyatki. Inflow of oxygen and glucose in brain tissue induced by intravenous norepinephrine: relationships with central metabolic and peripheral vascular responses. Journal of neurophysiology. vol 119. issue 2. 2019-05-01. PMID:29118201. |
to assess whether this effect is applicable to the brain, we used high-speed amperometry to measure the changes in nucleus accumbens (nac) levels of oxygen and glucose induced by intravenous injections of ne in awake freely moving rats. |
2019-05-01 |
2023-08-13 |
rat |
| Marcus M Weera, Zeynep S Agim, Jason R Cannon, Julia A Cheste. Genetic correlations between nicotine reinforcement-related behaviors and propensity toward high or low alcohol preference in two replicate mouse lines. Genes, brain, and behavior. vol 18. issue 3. 2019-05-01. PMID:30129253. |
in experiment 3, the effects of a single nicotine injection on nucleus accumbens (nac) and dorsal striatum monoamine levels in hap2/3 and lap2/3 mice were tested. |
2019-05-01 |
2023-08-13 |
mouse |
| Lei Chen, Nan Li, Shunnan Ge, Andres M Lozano, Darrin J Lee, Chen Yang, Liang Li, Qianrong Bai, Hongbing Lu, Jing Wang, Xin Wang, Jiaming Li, Jiangpeng Jing, Mingming Su, Longxiao Wei, Xuelian Wang, Guodong Ga. Long-term results after deep brain stimulation of nucleus accumbens and the anterior limb of the internal capsule for preventing heroin relapse: An open-label pilot study. Brain stimulation. vol 12. issue 1. 2019-05-01. PMID:30245163. |
deep brain stimulation (dbs) is currently used to treat addiction, with the nucleus accumbens (nac) as one promising target. |
2019-05-01 |
2023-08-13 |
Not clear |
| Benjamin P Gold, Ernest Mas-Herrero, Yashar Zeighami, Mitchel Benovoy, Alain Dagher, Robert J Zatorr. Musical reward prediction errors engage the nucleus accumbens and motivate learning. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 8. 2019-05-01. PMID:30728301. |
like many hedonic experiences, it engages several reward-related brain areas, with activity in the nucleus accumbens (nac) most consistently reflecting the listener's subjective response. |
2019-05-01 |
2023-08-13 |
human |
| Shannon L Cole, Mike J F Robinson, Kent C Berridg. Optogenetic self-stimulation in the nucleus accumbens: D1 reward versus D2 ambivalence. PloS one. vol 13. issue 11. 2019-04-23. PMID:30496206. |
the nucleus accumbens (nac) contains multiple subpopulations of medium spiny neurons (msns). |
2019-04-23 |
2023-08-13 |
mouse |
| Y Hanada, Y Kawahara, Y N Ohnishi, T Shuto, M Kuroiwa, N Sotogaku, P Greengard, Y Sagi, A Nish. p11 in Cholinergic Interneurons of the Nucleus Accumbens Is Essential for Dopamine Responses to Rewarding Stimuli. eNeuro. vol 5. issue 5. 2019-04-19. PMID:30417079. |
a recent study showed that p11 expressed in cholinergic interneurons (cins) of the nucleus accumbens (nac) is a key regulator of depression-like behaviors. |
2019-04-19 |
2023-08-13 |
mouse |
| Zahra Farzinpour, Zahra Taslimi, Ronak Azizbeigi, Saeideh Karimi-Haghighi, Abbas Haghparas. Involvement of orexinergic receptors in the nucleus accumbens, in the effect of forced swim stress on the reinstatement of morphine seeking behaviors. Behavioural brain research. vol 356. 2019-04-16. PMID:30195020. |
orexinergic system is involved in primary rewards; the neural circuit of the ventral tegmental area (vta), nucleus accumbens (nac), prefrontal cortex and amygdala represents overlapping elements mediating the rewarding effects of drugs and stressful experiences. |
2019-04-16 |
2023-08-13 |
rat |
| L Stan Leung, Jingyi M. Generalized seizures evoked by nucleus accumbens stimulation induced an opiate-mediated suppression of psychosis relevant behaviors. Behavioural brain research. vol 356. 2019-04-16. PMID:30218680. |
we have previously demonstrated that kindling of the nucleus accumbens (nac) induced psychosis relevant behaviors only after one, but not after five, stage-5 seizures, suggesting that five stage-5 nac-evoked seizures antagonized psychosis relevant behaviors in rats. |
2019-04-16 |
2023-08-13 |
rat |
| David Nguyen, Victoria Fugariu, Suzanne Erb, Rutsuko It. Dissociable roles of the nucleus accumbens D1 and D2 receptors in regulating cue-elicited approach-avoidance conflict decision-making. Psychopharmacology. vol 235. issue 8. 2019-04-03. PMID:29737363. |
the nucleus accumbens (nac), a site where valenced information and action selection converge, has recently been found to be critically involved in the resolution of approach-avoidance conflict. |
2019-04-03 |
2023-08-13 |
Not clear |
| Su-Hyun Kim, Eun Young Park, Boram Park, Jae-Won Hyun, Na Young Park, AeRan Joung, Sang Hyun Lee, Ho Jin Ki. Multimodal magnetic resonance imaging in relation to cognitive impairment in neuromyelitis optica spectrum disorder. Scientific reports. vol 7. issue 1. 2019-04-01. PMID:28835657. |
a multivariate model indicated that mean fa values in the wm and volume in the nucleus accumbens (nac) were associated with overall cognition (p = 0.002 and p = 0.008, respectively). |
2019-04-01 |
2023-08-13 |
Not clear |
| Jinxu Liu, Pauravi J Gandhi, Ratnamala Pavuluri, Gajanan P Shelkar, Shashank M Dravi. Glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens. Translational psychiatry. vol 8. issue 1. 2019-04-01. PMID:30315226. |
cocaine exposure induces plasticity of glutamatergic synapses of medium spiny neurons (msns) in the nucleus accumbens (nac), which has been proposed to contribute to its addictive behavior. |
2019-04-01 |
2023-08-13 |
mouse |
| M P Dandekar, A J Fenoy, A F Carvalho, J C Soares, J Queved. Deep brain stimulation for treatment-resistant depression: an integrative review of preclinical and clinical findings and translational implications. Molecular psychiatry. vol 23. issue 5. 2019-03-27. PMID:29483673. |
overall, 92 references met inclusion criteria, and have evaluated six unique dbs targets namely the subcallosal cingulate gyrus (scg), nucleus accumbens (nac), ventral capsule/ventral striatum or anterior limb of internal capsule (alic), medial forebrain bundle (mfb), lateral habenula (lhb) and inferior thalamic peduncle for the treatment of unrelenting trd. |
2019-03-27 |
2023-08-13 |
Not clear |
| Jun-Tao Gao, Chloe J Jordan, Guo-Hua Bi, Yi He, Hong-Ju Yang, Eliot L Gardner, Zheng-Xiong X. Deletion of the type 2 metabotropic glutamate receptor increases heroin abuse vulnerability in transgenic rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 13. 2019-03-26. PMID:30283001. |
compared to wild-type controls, mglur2-ko rats exhibited higher nucleus accumbens (nac) dopamine (da) and locomotor responses to heroin, higher heroin self-administration and heroin intake, more potent morphine-induced analgesia and more severe naloxone-precipitated withdrawal symptoms. |
2019-03-26 |
2023-08-13 |
rat |
| Fawaz Alasmari, Richard L Bell, P S S Rao, Alaa M Hammad, Youssef Sar. Peri-adolescent drinking of ethanol and/or nicotine modulates astroglial glutamate transporters and metabotropic glutamate receptor-1 in female alcohol-preferring rats. Pharmacology, biochemistry, and behavior. vol 170. 2019-03-22. PMID:29753887. |
the present study determined the effects of these reinforcers on glt-1, xct, glast, and mglur1 expression in the nucleus accumbens (nac), hippocampus (hip) and prefrontal cortex (pfc). |
2019-03-22 |
2023-08-13 |
rat |
| Darakhshan Jabeen Haleem, Shazia Nawaz, Tabinda Salma. Dopamine and serotonin metabolism associated with morphine reward and its inhibition with buspirone: A study in the rat striatum. Pharmacology, biochemistry, and behavior. vol 170. 2019-03-22. PMID:29782941. |
adaptations within the nucleus accumbens (nac) and caudate nucleus (cn) dopamine neurotransmission are involved in behavioral sensitization and enhanced incentive motivation towards drug paired stimuli which lead to drug addiction. |
2019-03-22 |
2023-08-13 |
rat |
| Katayoun Sedaghat, Zahra Yousefian, Abbas Ali Vafaei, Ali Rashidy-Pour, Houman Parsaei, Ali Khaleghian, Sara Choobda. Mesolimbic dopamine system and its modulation by vitamin D in a chronic mild stress model of depression in the rat. Behavioural brain research. vol 356. 2019-03-22. PMID:30144460. |
depression, a common mood disorder, involves anhedonia and defects in reward circuits and mesolimbic dopamine transmission in the striatum and nucleus accumbens (nac). |
2019-03-22 |
2023-08-13 |
rat |
| Natalia Fantin Sardi, Glaucia Tobaldini, Rosana Nogueira Morais, Luana Fische. Nucleus accumbens mediates the pronociceptive effect of sleep deprivation: the role of adenosine A2A and dopamine D2 receptors. Pain. vol 159. issue 1. 2019-03-21. PMID:28953191. |
it has been suggested that nucleus accumbens (nac) influences sleep-wake cycle by means of a balance between adenosine activity at a2a receptors and dopamine activity at d2 receptors. |
2019-03-21 |
2023-08-13 |
rat |
| Di Liu, Qian-Qian Tang, Cui Yin, Yu Song, Yan Liu, Jun-Xia Yang, He Liu, Yue-Man Zhang, Si-Yin Wu, Ying Song, Barbara Juarez, Hai-Lei Ding, Ming-Hu Han, Hongxing Zhang, Jun-Li Ca. Brain-derived neurotrophic factor-mediated projection-specific regulation of depressive-like and nociceptive behaviors in the mesolimbic reward circuitry. Pain. vol 159. issue 1. 2019-03-21. PMID:29076919. |
we demonstrated that cms decreased the firing activity in vta projecting to medial prefrontal cortex (vta → mpfc), but not in vta to nucleus accumbens (vta → nac), da neurons. |
2019-03-21 |
2023-08-13 |
mouse |
| Caroline E Germany, Ashlie N Reker, David J Hinton, Alfredo Oliveros, Xinggui Shen, Lindsey G Andres-Beck, Katheryn M Wininger, Marjan Trutschl, Urska Cvek, Doo-Sup Choi, Hyung W Na. Pharmacoproteomics Profile in Response to Acamprosate Treatment of an Alcoholism Animal Model. Proteomics. vol 18. issue 7. 2019-03-21. PMID:29437267. |
then, to elucidate acamprosate efficacy mechanism in ent1 null mice, the authors utilize label-free quantification proteomics comparing both genotype and acamprosate treatment effects in the nucleus accumbens (nac). |
2019-03-21 |
2023-08-13 |
mouse |
| Debra A Bercovici, Oren Princz-Lebel, Maric T Tse, David E Moorman, Stan B Floresc. Optogenetic Dissection of Temporal Dynamics of Amygdala-Striatal Interplay during Risk/Reward Decision Making. eNeuro. vol 5. issue 6. 2019-03-21. PMID:30627636. |
previous studies using pharmacological inactivations have shown that the basolateral amygdala (bla) to nucleus accumbens (nac) pathway promotes choice towards larger/riskier rewards. |
2019-03-21 |
2023-08-13 |
rat |