| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katsuyuki Kaneda, Satoshi Deyama, Eiichi Hinoi, Junko Yanagida, Tong Zhang, Hitoki Sasas. [Analyses of cocaine rewarding memories by AAV vector-induced introduction of DREADD system]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 153. issue 5. 2019-08-13. PMID:31092754. |
the development and persistence of drug addiction are associated with the activation and adaptation of the brain reward circuitry, which consists of dopaminergic projection from the ventral tegmental area to the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc). |
2019-08-13 |
2023-08-13 |
mouse |
| Ernesto Solis, Anum Afzal, Eugene A Kiyatki. Opposing mechanisms underlying differential changes in brain oxygen and temperature induced by intravenous morphine. Journal of neurophysiology. vol 120. issue 5. 2019-08-02. PMID:30183460. |
we used oxygen sensors coupled with high-speed amperometry and conducted measurements in the nucleus accumbens (nac) and subcutaneous (sc) space, the latter serving as a proxy for blood oxygen levels that depend on respiratory activity. |
2019-08-02 |
2023-08-13 |
rat |
| N Yao, O Skiteva, X Zhang, P Svenningsson, K Chergu. Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit. Molecular psychiatry. vol 23. issue 10. 2019-07-31. PMID:29158578. |
we found that one day after the injection of a low dose of ketamine, long-term potentiation (ltp) in the nucleus accumbens (nac) was impaired. |
2019-07-31 |
2023-08-13 |
mouse |
| Negar Baharlouei, Abdolrahman Sarihi, Marzieh Moradi, Shahram Zarrabian, Abbas Haghparas. Microinjection of the mGluR2/3 agonist, LY379268, into the nucleus accumbens attenuates extinction latencies and the reinstatement of morphine-induced conditioned place preference in rats. Behavioural pharmacology. vol 29. issue 5. 2019-07-31. PMID:29462112. |
the nucleus accumbens (nac), which is one of the important areas involved in the reward circuitry, also expresses these receptors. |
2019-07-31 |
2023-08-13 |
rat |
| Krystal Iacopetta, Lyndsey E Collins-Praino, Femke T A Buisman-Pijlman, Mark R Hutchinso. Can neuroimmune mechanisms explain the link between ultraviolet light (UV) exposure and addictive behavior? Brain, behavior, and immunity. vol 73. 2019-07-31. PMID:30009997. |
as both neurotransmitter systems play a key role in the development of addiction behaviors through their actions at key brain regions, such as the nucleus accumbens (nac), we hypothesize a novel connection between uv-induced inflammation and the activation of pathways that contribute to the development of addiction. |
2019-07-31 |
2023-08-13 |
Not clear |
| Sean J Reed, Christopher K Lafferty, Jesse A Mendoza, Angela K Yang, Thomas J Davidson, Logan Grosenick, Karl Deisseroth, Jonathan P Brit. Coordinated Reductions in Excitatory Input to the Nucleus Accumbens Underlie Food Consumption. Neuron. vol 99. issue 6. 2019-07-30. PMID:30146308. |
reward-seeking behavior is regulated by a diverse collection of inputs to the nucleus accumbens (nac). |
2019-07-30 |
2023-08-13 |
mouse |
| Hossein Khaleghzadeh-Ahangar, Fariba Khodagholi, Fatemeh Shaerzadeh, Abbas Haghparas. Modulatory role of the intra-accumbal CB1 receptor in protein level of the c-fos and pCREB/CREB ratio in the nucleus accumbens and ventral tegmental area in extinction and morphine seeking in the rats. Brain research bulletin. vol 142. 2019-07-30. PMID:30170186. |
brain reward and motivation circuit begin from the ventral tegmental area (vta) that its dopaminergic terminals project to various regions of the brain including the nucleus accumbens (nac). |
2019-07-30 |
2023-08-13 |
rat |
| Natasha L Mason, Eef L Theunissen, Nadia R P W Hutten, Desmond H Y Tse, Stefan W Toennes, Peter Stiers, Johannes G Ramaeker. Cannabis induced increase in striatal glutamate associated with loss of functional corticostriatal connectivity. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 2. 2019-07-30. PMID:30553697. |
administration of thc increased striatal glutamate concentrations, and dopamine as indicated by a reduction in functional connectivity (fc) between the nucleus accumbens (nac) and cortical areas. |
2019-07-30 |
2023-08-13 |
Not clear |
| Giulia Costa, Pier Francesca Porceddu, Marcello Serra, Maria Antonietta Casu, Valentina Schiano, Francesco Napolitano, Annalisa Pinna, Alessandro Usiello, Micaela Morell. Lack of Rhes Increases MDMA-Induced Neuroinflammation and Dopamine Neuron Degeneration: Role of Gender and Age. International journal of molecular sciences. vol 20. issue 7. 2019-07-29. PMID:30925704. |
in these mice, the increase of cd11b was more extensive including str, snc, motor cortex (ctx), ventral tegmental area (vta), and nucleus accumbens (nac). |
2019-07-29 |
2023-08-13 |
mouse |
| Hongbin Yang, Johannes W de Jong, YeEun Tak, James Peck, Helen S Bateup, Stephan Lamme. Nucleus Accumbens Subnuclei Regulate Motivated Behavior via Direct Inhibition and Disinhibition of VTA Dopamine Subpopulations. Neuron. vol 97. issue 2. 2019-07-17. PMID:29307710. |
neurons in the medial shell subdivision of the nucleus accumbens (nac) exert direct inhibitory control over two separate populations of mesolimbic da neurons by activating different gaba receptor subtypes. |
2019-07-17 |
2023-08-13 |
Not clear |
| Anna Beyeler, Chia-Jung Chang, Margaux Silvestre, Clémentine Lévêque, Praneeth Namburi, Craig P Wildes, Kay M Ty. Organization of Valence-Encoding and Projection-Defined Neurons in the Basolateral Amygdala. Cell reports. vol 22. issue 4. 2019-07-15. PMID:29386133. |
accumulating evidence supports the notion that different bla projections distinctly alter motivated behavior, including projections to the nucleus accumbens (nac), medial aspect of the central amygdala (cem), and ventral hippocampus (vhpc). |
2019-07-15 |
2023-08-13 |
Not clear |
| Pamela F Marcott, Sheng Gong, Prashant Donthamsetti, Steven G Grinnell, Melissa N Nelson, Amy H Newman, Lutz Birnbaumer, Kirill A Martemyanov, Jonathan A Javitch, Christopher P For. Regional Heterogeneity of D2-Receptor Signaling in the Dorsal Striatum and Nucleus Accumbens. Neuron. vol 98. issue 3. 2019-07-15. PMID:29656874. |
here we examined the activation of d2 receptors following the synaptic release of dopamine in the dorsal striatum (dstr) and nucleus accumbens (nac) shell. |
2019-07-15 |
2023-08-13 |
Not clear |
| Sanjeev K Bhardwaj, Fatéma Dodat, Daniel Lévesque, Lalit K Srivastav. Altered regulation of Nur77 nuclear receptor gene expression in the mesocorticolimbic regions of rat brain by amphetamine sensitization. Brain research. vol 1694. 2019-07-11. PMID:29750935. |
here we evaluated changes in nur77 mrna levels in the medial prefrontal cortex (mpfc), dorsal striatum (str) and nucleus accumbens (nac) of rats receiving a repeated, sensitizing regimen of amphetamine (amph). |
2019-07-11 |
2023-08-13 |
rat |
| Lukas Maurer, Hui Tang, Jens K Haumesser, Jennifer Altschüler, Andrea A Kühn, Joachim Spranger, Christoph van Riese. High-fat diet-induced obesity and insulin resistance are characterized by differential beta oscillatory signaling of the limbic cortico-basal ganglia loop. Scientific reports. vol 7. issue 1. 2019-07-09. PMID:29138510. |
our analysis demonstrates increased oscillatory beta power in the nucleus accumbens (nac) associated with decreased beta coherence between cortex and nac in animals fed a hfd. |
2019-07-09 |
2023-08-13 |
rat |
| Ramesh Chandra, Michel Engeln, Christopher Schiefer, Mary H Patton, Jennifer A Martin, Craig T Werner, Lace M Riggs, T Chase Francis, Madeleine McGlincy, Brianna Evans, Hyungwoo Nam, Shweta Das, Kasey Girven, Prasad Konkalmatt, Amy M Gancarz, Sam A Golden, Sergio D Iñiguez, Scott J Russo, Gustavo Turecki, Brian N Mathur, Meaghan Creed, David M Dietz, Mary Kay Lob. Drp1 Mitochondrial Fission in D1 Neurons Mediates Behavioral and Cellular Plasticity during Early Cocaine Abstinence. Neuron. vol 96. issue 6. 2019-07-05. PMID:29268097. |
we demonstrate an increase of dynamin-related protein-1 (drp1), the mitochondrial fission mediator, in nucleus accumbens (nac) after repeated cocaine exposure and in cocaine-dependent individuals. |
2019-07-05 |
2023-08-13 |
Not clear |
| Marco Pignatelli, Antonello Bonc. Spiraling Connectivity of NAc-VTA Circuitry. Neuron. vol 97. issue 2. 2019-07-02. PMID:29346748. |
how do nucleus accumbens (nac) subdivisions shape information flow into distinct ventral tegmental area (vta) subcircuits? |
2019-07-02 |
2023-08-13 |
Not clear |
| Elizabeth M Doncheck, Madalyn Hafenbreidel, Sarah A Ruder, Michael K Fitzgerald, Lilith Torres, Devin Muelle. bFGF expression is differentially regulated by cocaine seeking versus extinction in learning-related brain regions. Learning & memory (Cold Spring Harbor, N.Y.). vol 25. issue 8. 2019-07-02. PMID:30012881. |
therefore, we used the conditioned place preference (cpp) paradigm to assess bfgf expression following cocaine-associated cpp or extinction of that cpp within the mpfc, nucleus accumbens (nac), hippocampus (hipp), and basolateral amygdala (bla). |
2019-07-02 |
2023-08-13 |
Not clear |
| Alaa M Hammad, Fawaz Alasmari, Youssef Sari, F Scott Hall, Amit K Tiwar. Alcohol and Cocaine Exposure Modulates ABCB1 and ABCG2 Transporters in Male Alcohol-Preferring Rats. Molecular neurobiology. vol 56. issue 3. 2019-07-01. PMID:29978425. |
in this study, we determined the effects of voluntary ethanol consumption following repeated exposure to cocaine or vehicle on the relative mrna and protein expression of abcg2/abcg2 and abcb1/abcb1 in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) of male alcohol-preferring (p) rats. |
2019-07-01 |
2023-08-13 |
rat |
| Lixia Xiong, Qing Meng, Xi Sun, Xiangtong Lu, Qiang Fu, Qinghua Peng, Jianhua Yang, Ki-Wan Oh, Zhenzhen H. Cocaine- and amphetamine-regulated transcript peptide in the nucleus accumbens shell inhibits cocaine-induced locomotor sensitization to transient over-expression of α-Ca Journal of neurochemistry. vol 146. issue 3. 2019-06-26. PMID:29313985. |
cocaine- and amphetamine-regulated transcript peptide in the nucleus accumbens shell inhibits cocaine-induced locomotor sensitization to transient over-expression of α-ca cocaine- and amphetamine-regulated transcript (cart) peptide is a widely distributed neurotransmitter that attenuates cocaine-induced locomotor activity when injected into the nucleus accumbens (nac). |
2019-06-26 |
2023-08-13 |
Not clear |
| Daniel Knowland, Byung Kook Li. Circuit-based frameworks of depressive behaviors: The role of reward circuitry and beyond. Pharmacology, biochemistry, and behavior. vol 174. 2019-06-24. PMID:29309799. |
in particular, areas such as the ventral tegmental area (vta), nucleus accumbens (nac), and ventral pallidum (vp) are thought to generally promote reward, with the medial prefrontal cortex (mpfc) providing top-down control of reward seeking. |
2019-06-24 |
2023-08-13 |
Not clear |