| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mei Bai, Xiongzhao Zhu, Li Zhang, Yi Zhang, Liang Xue, Yuting Wang, Mingtian Zhong, Xiuwu Zhan. Divergent anomaly in mesocorticolimbic dopaminergic circuits might be associated with different depressive behaviors, an animal study. Brain and behavior. vol 7. issue 10. 2018-07-09. PMID:29075568. |
the mesocorticolimbic dopamine system, which originates from the ventral tegmental area (vta) and projects primarily to the prefrontal cortex (pfc), olfactory tubercle (ot), nucleus accumbens (nac), dorsal striatum (st), and the amygdala (amy), plays a pivotal role in determining individual motivation and sensitivity to rewards, namely, anhedonia. |
2018-07-09 |
2023-08-13 |
Not clear |
| Hemmings Wu, Kai J Miller, Zack Blumenfeld, Nolan R Williams, Vinod K Ravikumar, Karen E Lee, Bina Kakusa, Matthew D Sacchet, Max Wintermark, Daniel J Christoffel, Brian K Rutt, Helen Bronte-Stewart, Brian Knutson, Robert C Malenka, Casey H Halper. Closing the loop on impulsivity via nucleus accumbens delta-band activity in mice and man. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 1. 2018-07-09. PMID:29255043. |
temporally specific changes in activity within the nucleus accumbens (nac), which occur during anticipatory periods preceding consummatory behavior, represent a critical opportunity for intervention. |
2018-07-09 |
2023-08-13 |
mouse |
| Chayaporn Reakkamnuan, Dania Cheaha, Ekkasit Kumarnsi. Nucleus accumbens local field potential power spectrums, phase-amplitude couplings and coherences following morphine treatment. Acta neurobiologiae experimentalis. vol 77. issue 3. 2018-07-06. PMID:29182612. |
however, neural signaling in the nucleus accumbens (nac) that might clarify reward process remained to be investigated. |
2018-07-06 |
2023-08-13 |
mouse |
| Maw Shin Sim, Tomoko Soga, Vijayapandi Pandy, Yuan Seng Wu, Ishwar S Parhar, Zahurin Mohame. MicroRNA expression signature of methamphetamine use and addiction in the rat nucleus accumbens. Metabolic brain disease. vol 32. issue 6. 2018-07-03. PMID:28681200. |
nucleus accumbens (nac) plays an important role in these changes, especially in drug addiction. |
2018-07-03 |
2023-08-13 |
rat |
| Binbin Wu, Wenxuan Lin, Hong Wang, Taha Abdullah, Benfu Wang, Ying Su, Ren-Shan Ge, Qingquan Lia. Glucocorticoid receptor in rat nucleus accumbens: Its roles in propofol addictions. Neuroscience letters. vol 662. 2018-07-02. PMID:29037790. |
however, the direct effect of gr in the nucleus accumbens (nac) on propofol self-administration behavior has not been explored. |
2018-07-02 |
2023-08-13 |
rat |
| Ali Siahposht-Khachaki, Somayeh Ezzatpanah, Yasaman Razavi, Abbas Haghparas. NMDA receptor dependent changes in c-fos and p-CREB signaling following extinction and reinstatement of morphine place preference. Neuroscience letters. vol 662. 2018-06-29. PMID:29054430. |
neural circuitry comprising the ventral tegmental area, nucleus accumbens (nac), prefrontal cortex (pfc) and hippocampus (hip) has a main role in reward phenomena. |
2018-06-29 |
2023-08-13 |
rat |
| Hossein Khaleghzadeh-Ahangar, Abbas Haghparas. Intra-accumbal Cannabinoid Agonist Attenuated Reinstatement but not Extinction Period of Morphine-Induced Conditioned Place Preference; Evidence for Different Characteristics of Extinction Period and Reinstatement. Neurochemical research. vol 42. issue 11. 2018-06-26. PMID:28780734. |
the brain reward system consists of the ventral tegmental area that sends its dopaminergic projections to the forebrain, cortical areas, amygdala and largely to the nucleus accumbens (nac). |
2018-06-26 |
2023-08-13 |
rat |
| Caddy N Hobbs, Gordon Holzberg, Akira S Min, R Mark Wightma. Comparison of Spreading Depolarizations in the Motor Cortex and Nucleus Accumbens: Similar Patterns of Oxygen Responses and the Role of Dopamine. ACS chemical neuroscience. vol 8. issue 11. 2018-06-26. PMID:28820571. |
here, we describe sd responses in the cortex and the deep brain region of the nucleus accumbens (nac) of the anesthetized rat with a minimally invasive, implantable sensor. |
2018-06-26 |
2023-08-13 |
rat |
| Jun Yu, Yijin Yan, King-Lun Li, Yao Wang, Yanhua H Huang, Nathaniel N Urban, Eric J Nestler, Oliver M Schlüter, Yan Don. Nucleus accumbens feedforward inhibition circuit promotes cocaine self-administration. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 41. 2018-06-26. PMID:28973852. |
the basolateral amygdala (bla) sends excitatory projections to the nucleus accumbens (nac) and regulates motivated behaviors partially by activating nac medium spiny neurons (msns). |
2018-06-26 |
2023-08-13 |
Not clear |
| Xinwen Dong, Sa Li, Gilbert J Kiroua. Collateralization of projections from the paraventricular nucleus of the thalamus to the nucleus accumbens, bed nucleus of the stria terminalis, and central nucleus of the amygdala. Brain structure & function. vol 222. issue 9. 2018-06-25. PMID:28528379. |
the paraventricular nucleus of the thalamus (pvt) is a midline thalamic nucleus with dense projections to the nucleus accumbens (nac), dorsolateral region of the bed nucleus of the stria terminalis (bstdl) and the lateral/capsular region of the central nucleus of the amygdala (cel/cec). |
2018-06-25 |
2023-08-13 |
Not clear |
| Daniel S Wheeler, Amanda L Ebben, Beliz Kurtoglu, Marissa E Lovell, Austin T Bohn, Isabella A Jasek, David A Baker, John R Mantsch, Paul J Gasser, Robert A Wheele. Corticosterone regulates both naturally occurring and cocaine-induced dopamine signaling by selectively decreasing dopamine uptake. The European journal of neuroscience. vol 46. issue 10. 2018-06-22. PMID:28965353. |
this effect is also observed when the stress hormone corticosterone is administered directly into the nucleus accumbens (nac), indicating that glucocorticoids act locally in dopamine terminal regions to enhance cocaine's effects on dopamine signaling. |
2018-06-22 |
2023-08-13 |
rat |
| Sara E Morrison, Vincent B McGinty, Johann du Hoffmann, Saleem M Nicol. Limbic-motor integration by neural excitations and inhibitions in the nucleus accumbens. Journal of neurophysiology. vol 118. issue 5. 2018-06-19. PMID:28794196. |
the nucleus accumbens (nac) has often been described as a "limbic-motor interface," implying that the nac integrates the value of expected rewards with the motor planning required to obtain them. |
2018-06-19 |
2023-08-13 |
rat |
| Hui Ye, Jingxin Wang, Zichuan Tian, Fengfei Ma, James Dowell, Quentin Bremer, Gaoyuan Lu, Brian Baldo, Lingjun L. Quantitative Mass Spectrometry Reveals Food Intake-Induced Neuropeptide Level Changes in Rat Brain: Functional Assessment of Selected Neuropeptides as Feeding Regulators. Molecular & cellular proteomics : MCP. vol 16. issue 11. 2018-06-19. PMID:28864778. |
previous work has shown that neuropeptide gene expression levels in a forebrain reward site, the nucleus accumbens (nac), were changed by feeding. |
2018-06-19 |
2023-08-13 |
rat |
| Ernesto Solis, Keaton T Cameron-Burr, Eugene A Kiyatki. Heroin Contaminated with Fentanyl Dramatically Enhances Brain Hypoxia and Induces Brain Hypothermia. eNeuro. vol 4. issue 5. 2018-06-14. PMID:29085909. |
since respiratory depression that leads to acute hypoxia is the most dangerous complication of opioid drug use, we examined the effects of intravenous heroin and heroin contaminated with 10% fentanyl on oxygen levels in the nucleus accumbens (nac) monitored using high-speed amperometry in freely moving rats. |
2018-06-14 |
2023-08-13 |
rat |
| Mariusz Papp, Piotr Gruca, Magdalena Lason-Tyburkiewicz, Ewa Litwa, Monika Niemczyk, Katarzyna Tota-Glowczyk, Paul Willne. Dopaminergic mechanisms in memory consolidation and antidepressant reversal of a chronic mild stress-induced cognitive impairment`. Psychopharmacology. vol 234. issue 17. 2018-06-13. PMID:28567697. |
in experiments 1 and 2, we examined the effect of infusions into medial pfc, dorsal hippocampus (hpc), and nucleus accumbens (nac) shell of d1 and d2 antagonists and d3 agonist, which were predicted to impair nor with a short (1 h) delay, and of d1 and d2 agonists and d3 antagonist, which were predicted to facilitate nor with a long (24 h) delay. |
2018-06-13 |
2023-08-13 |
Not clear |
| Jin W Park, Rohan V Bhimani, Jinwoo Par. Noradrenergic Modulation of Dopamine Transmission Evoked by Electrical Stimulation of the Locus Coeruleus in the Rat Brain. ACS chemical neuroscience. vol 8. issue 9. 2018-06-12. PMID:28594540. |
herein, we investigated how electrical stimulation of the lc modulates vta-da neurotransmission in the nucleus accumbens (nac). |
2018-06-12 |
2023-08-13 |
rat |
| Idu Azogu, Helene Plamondo. Inhibition of TrkB at the nucleus accumbens, using ANA-12, regulates basal and stress-induced orexin A expression within the mesolimbic system and affects anxiety, sociability and motivation. Neuropharmacology. vol 125. 2018-06-12. PMID:28705440. |
an emerging biological substrate of depression and associated pathology is the nucleus accumbens (nac), which through interactions with limbic, cognitive and motor circuits can regulate a variety of stress responses. |
2018-06-12 |
2023-08-13 |
rat |
| R Aaron Bola, Eugene A Kiyatki. Brain temperature effects of intravenous heroin: State dependency, environmental modulation, and the effects of dose. Neuropharmacology. vol 126. 2018-06-12. PMID:28755887. |
when administered under standard laboratory conditions (quiet rest at 22 °c ambient temperature), heroin induced moderate temperature increases (1.0-1.5 °c) in the nucleus accumbens (nac), a critical structure of the brain motivation-reinforcement circuit. |
2018-06-12 |
2023-08-13 |
human |
| Mirmohammadali Mirramezani Alizamini, Zahra Farzinpour, Somayeh Ezzatpanah, Abbas Haghparas. Role of intra-accumbal orexin receptors in the acquisition of morphine-induced conditioned place preference in the rats. Neuroscience letters. vol 660. 2018-06-11. PMID:28889006. |
in the present study, we investigated the effects of bilateral administration of sb334867, as an orexin-1 receptor antagonist, and tcs ox2 29, as an orexin-2 receptor antagonist, into the nucleus accumbens (nac) on the acquisition of morphine-induced conditioned place preference (cpp) in the rats. |
2018-06-11 |
2023-08-13 |
rat |
| Mengbing Huang, Lingpin Kong, Lihua Yang, Xiang Li, Xiaoshuang Zhou, Ye Li, Jie Ba. The role of thioredoxin-1 in resisting methamphetamine-induced rewarding effect. Behavioural brain research. vol 337. 2018-06-08. PMID:28782589. |
in this study, we examined the rewarding effect after meth administration by conditioned place preference (cpp) of mice, and detected the levels of dopamine and the activity of camp responsive element-binding protein (creb), the expressions of Δfosb and cyclin-dependent kinase 5 (cdk5) in the ventral tegmental area (vta) and nucleus accumbens (nac) in mice. |
2018-06-08 |
2023-08-13 |
mouse |