| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kunjumon Ittira Vadakka. Framework for internal sensation of pleasure using constraints from disparate findings in nucleus accumbens. World journal of psychiatry. vol 11. issue 10. 2021-11-05. PMID:34733636. |
the actual mechanism is expected to explain several disparate findings in nucleus accumbens (nac), a brain region associated with pleasure, in an interconnected manner. |
2021-11-05 |
2023-08-13 |
Not clear |
| Rocío Guerrero-Bautista, Aurelio Franco-García, Juana M Hidalgo, Francisco Fernández-Gómez, M Victoria Milanés, Cristina Núñe. Blockade of D3 receptor prevents changes in DAT and D3R expression in the mesolimbic dopaminergic circuit produced by social stress- and cocaine prime-induced reinstatement of cocaine-CPP. Journal of psychopharmacology (Oxford, England). vol 34. issue 11. 2021-11-04. PMID:32648812. |
cocaine may cause persistent changes in the brain, which are more apparent in da transporter (dat) and da receptor availability within the nucleus accumbens (nac). |
2021-11-04 |
2023-08-13 |
Not clear |
| You-Hsin Lin, Yukie Yamahashi, Keisuke Kuroda, Md Omar Faruk, Xinjian Zhang, Kiyofumi Yamada, Akihiro Yamanaka, Taku Nagai, Kozo Kaibuch. Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway. Neurochemistry international. vol 143. 2021-11-04. PMID:33301817. |
the nucleus accumbens (nac) plays a crucial role in various mental activities, including positive and negative reinforcement. |
2021-11-04 |
2023-08-13 |
mouse |
| Fei Zeng, Qiaosheng Zhang, Yaling Liu, Guanghao Sun, Anna Li, Robert S Talay, Jing Wan. AMPAkines potentiate the corticostriatal pathway to reduce acute and chronic pain. Molecular brain. vol 14. issue 1. 2021-11-04. PMID:33653395. |
specifically, the projection from the prelimbic cortex (pl) to the nucleus accumbens (nac) has been shown to regulate sensory and affective aspects of pain in a number of rodent models. |
2021-11-04 |
2023-08-13 |
rat |
| Xia-Qing Wang, Tahmineh Mokhtari, Yu-Xuan Zeng, Lu-Peng Yue, Li H. The Distinct Functions of Dopaminergic Receptors on Pain Modulation: A Narrative Review. Neural plasticity. vol 2021. 2021-11-04. PMID:33688340. |
in the present report, we have reviewed the analgesic effects of different dopamine receptors, particularly d1 and d2 receptors, in different regions of the central nervous system, including the spinal cord, striatum, nucleus accumbens (nac), and periaqueductal gray (pag). |
2021-11-04 |
2023-08-13 |
Not clear |
| Wei-Wei Bao, Wei Xu, Gao-Jie Pan, Tian-Xiao Wang, Yuan Han, Wei-Min Qu, Wen-Xian Li, Zhi-Li Huan. Nucleus accumbens neurons expressing dopamine D1 receptors modulate states of consciousness in sevoflurane anesthesia. Current biology : CB. vol 31. issue 9. 2021-11-04. PMID:33705720. |
here, we found that population activities of neurons expressing dopamine d1 receptor (d1r) in the nucleus accumbens (nac), a critical interface between the basal ganglia and limbic system, began to decrease before sevoflurane-induced loc and gradually returned after recovery of consciousness (roc). |
2021-11-04 |
2023-08-13 |
Not clear |
| Hashem Saberian, Afsaneh Asgari Taei, Anahita Torkaman-Boutorabi, Esmail Riahi, Samaneh Aminyavari, Ayeh Naghizadeh, Maryam Farahmandfa. Effect of histone acetylation on maintenance and reinstatement of morphine-induced conditioned place preference and ΔFosB expression in the nucleus accumbens and prefrontal cortex of male rats. Behavioural brain research. vol 414. 2021-11-04. PMID:34302880. |
h4 acetylation and Δfosb expression in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) were assessed on the last day of extinction and the following cpp reinstatement. |
2021-11-04 |
2023-08-13 |
rat |
| Wenqi Cai, Huan Ma, Yufeng Xun, Wenjuan Hou, Limin Wang, Xueni Zhang, Yufeng Ran, Wei Yuan, Qianqian Guo, Jing Zhang, Laifu Li, Yang Yang, Yitong Li, Zijian Lv, Zhixiong He, Rui Jia, Fadao Ta. Involvement of the dopamine system in paternal behavior induced by repeated pup exposure in virgin male ICR mice. Behavioural brain research. vol 415. 2021-11-04. PMID:34389426. |
repeated pup exposure increased c-fos-positive neurons and the levels of dopamine- and th-positive neurons in the nucleus accumbens (nac). |
2021-11-04 |
2023-08-13 |
mouse |
| Ai T M Nguyen, Tran V B Quach, Peddanna Kotha, Szu-Yu Chien, Iona J MacDonald, Hsien-Yuan Lane, Cheng-Hao Tu, Jaung-Geng Lin, Yi-Hung Che. Electroacupuncture prevents cocaine-induced conditioned place preference reinstatement and attenuates ΔFosB and GluR2 expression. Scientific reports. vol 11. issue 1. 2021-11-03. PMID:34211013. |
this experimental study compared the effects of electroacupuncture (ea) at acupoints li4 and li11 with those of another potentially beneficial intervention, gabapentin (gbp), alone or in combination, on reinstatement of cocaine-induced conditioned place preference (cpp) and levels of Δfosb and glutamate receptor subunit 2 (glur2) expression in the nucleus accumbens (nac). |
2021-11-03 |
2023-08-13 |
Not clear |
| Gui-Ying Zan, Yu-Jun Wang, Xue-Ping Li, Jun-Fan Fang, Song-Yu Yao, Jun-Ying Du, Qian Wang, Xiang Sun, Rui Liu, Xiao-Mei Shao, Jian-Dong Long, Jing-Rui Chai, Ying-Zhi Deng, Ye-Qing Chen, Qing-Lin Li, Jian-Qiao Fang, Zhi-Qiang Liu, Jing-Gen Li. Amygdalar κ-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence. Cell reports. vol 37. issue 5. 2021-11-03. PMID:34731618. |
upregulation of glt1 expression contributes to opiate-abstinence-elicited depressive-like behaviors through modulating amygdalar glutamatergic inputs to the nucleus accumbens (nac). |
2021-11-03 |
2023-08-13 |
Not clear |
| Zeinab Khastkhodaei, Muthuraman Muthuraman, Jenq-Wei Yang, Sergiu Groppa, Heiko J Luhman. Functional and directed connectivity of the cortico-limbic network in mice in vivo. Brain structure & function. vol 226. issue 3. 2021-11-02. PMID:33442810. |
central structures of this cortico-limbic network are ventral hippocampus (vhc), medial prefrontal cortex (pfc), basolateral amygdala (bla) and nucleus accumbens (nac). |
2021-11-02 |
2023-08-13 |
mouse |
| Jesper Vestlund, Filip Bergquist, Valentina Licheri, Louise Adermark, Elisabet Jerlha. Activation of glucagon-like peptide-1 receptors and skilled reach foraging. Addiction biology. vol 26. issue 3. 2021-11-01. PMID:32770792. |
acute activation of glp-1r in the nucleus accumbens (nac) shell, an area essential for motivation, reduces the motivation to consume sucrose or alcohol when assessed in a simple motor task. |
2021-11-01 |
2023-08-13 |
rat |
| Anna Loftén, Louise Adermark, Mia Ericson, Bo Söderpal. An acetylcholine-dopamine interaction in the nucleus accumbens and its involvement in ethanol's dopamine-releasing effect. Addiction biology. vol 26. issue 3. 2021-11-01. PMID:32789970. |
cholinergic interneurons (cin) within the nucleus accumbens (nac) have been suggested to exert a regulatory impact on dopamine (da) neurotransmission locally, and defects in cin have been implied in several psychiatric disorders. |
2021-11-01 |
2023-08-13 |
rat |
| Andrew T Gargiulo, Breanne E Pirino, Genevieve R Curtis, Jessica R Barso. Effects of pituitary adenylate cyclase-activating polypeptide isoforms in nucleus accumbens subregions on ethanol drinking. Addiction biology. vol 26. issue 3. 2021-11-01. PMID:33020973. |
one region that has been found both to exhibit pacap binding and, separately, to be involved in ethanol drinking is the nucleus accumbens (nac). |
2021-11-01 |
2023-08-13 |
rat |
| Casey K Lardner, Yentl van der Zee, Molly S Estill, Hope G Kronman, Marine Salery, Ashley M Cunningham, Arthur Godino, Eric M Parise, Jee Hyun Kim, Rachael L Neve, Li Shen, Peter J Hamilton, Eric J Nestle. Gene-Targeted, CREB-Mediated Induction of ΔFosB Controls Distinct Downstream Transcriptional Patterns Within D1 and D2 Medium Spiny Neurons. Biological psychiatry. vol 90. issue 8. 2021-11-01. PMID:34425966. |
Δfosb is a transcription factor that accumulates in the nucleus accumbens (nac)-a brain region responsible for coordinating reward and motivation-after exposure to virtually every known rewarding substance, including cocaine and opioids. |
2021-11-01 |
2023-08-13 |
Not clear |
| Erik J Garcia, Mary E Cai. Isolation housing elevates amphetamine seeking independent of nucleus accumbens glutamate receptor adaptations. The European journal of neuroscience. vol 54. issue 7. 2021-11-01. PMID:34481424. |
preclinical models have determined that glutamate receptor plasticity within the nucleus accumbens (nac) drives amplified cue-evoked drug seeking after prolonged abstinence (>40 days). |
2021-11-01 |
2023-08-13 |
rat |
| Kolter B Grigsby, Thomas E Childs, Frank W Boot. The role of nucleus accumbens CREB attenuation in rescuing low voluntary running behavior in female rats. Journal of neuroscience research. vol 98. issue 11. 2021-10-29. PMID:32725625. |
given the integral role of nucleus accumbens (nac) camp response element binding protein (creb) activity in motivational processes, the goal of the current study was to determine whether blunting chronic nac creb activity could rescue the low physical activity motivation of female, low voluntary running (lvr) rats. |
2021-10-29 |
2023-08-13 |
human |
| b' F Quessy, T Bittar, L J Blanchette, M L\\xc3\\xa9vesque, B Labont\\xc3\\xa. Stress-induced alterations of mesocortical and mesolimbic dopaminergic pathways. Scientific reports. vol 11. issue 1. 2021-10-29. PMID:34040100.' |
density of the mesolimbic and mesocortical projections was assessed via immuno-histochemistry combined with sholl analysis along with the staining of activity-dependent markers perk and c-fos in the ventral tegmental area (vta), nucleus accumbens (nac) and medial prefrontal cortex (mpfc). |
2021-10-29 |
2023-08-13 |
mouse |
| Iwona Olejniczak, Jürgen A Ripperger, Federica Sandrelli, Anna Schnell, Laureen Mansencal-Strittmatter, Katrin Wendrich, Ka Yi Hui, Andrea Brenna, Naila Ben Fredj, Urs Albrech. Light affects behavioral despair involving the clock gene Period 1. PLoS genetics. vol 17. issue 7. 2021-10-29. PMID:34237069. |
in the nucleus accumbens (nac), sensory perception of smell and g-protein coupled receptor signaling were affected the most. |
2021-10-29 |
2023-08-13 |
mouse |
| Katherine N Wright, Daniel W Wesso. The tubular striatum and nucleus accumbens distinctly represent reward-taking and reward-seeking. Journal of neurophysiology. vol 125. issue 1. 2021-10-28. PMID:33174477. |
the ventral striatum contains both the nucleus accumbens (nac), which is well established to contribute to motivated behavior, and the adjacent tubular striatum (tus), which is poorly understood in this context. |
2021-10-28 |
2023-08-13 |
mouse |