| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yingliang Xie, Peizhen Wang, Xiaoyan Cui, Lei Liu, Pengcheng Wang, Shimei Jing, Qi Liu, Yuting Wang, Shiqiang Wan. Dopaminergic neurons project to the nucleus accumbens regulates anxiety-like behaviors through dopamine D Behavioural brain research. vol 416. 2021-10-05. PMID:34419513. |
our c-fos labeling results showed that da neurons projected to nucleus accumbens (nac) are activated in animals treated with the elevated plus-maze (epm). |
2021-10-05 |
2023-08-13 |
mouse |
| Allen L Ho, Austin Y Feng, Daniel A N Barbosa, Hemmings Wu, Monique L Smith, Robert C Malenka, Peter A Tass, Casey H Halper. Accumbens coordinated reset stimulation in mice exhibits ameliorating aftereffects on binge alcohol drinking. Brain stimulation. vol 14. issue 2. 2021-10-04. PMID:33524612. |
despite treatment, aud often manifests with relapse to binge drinking, which has been associated with corticostriatal hypersynchrony involving the nucleus accumbens (nac). |
2021-10-04 |
2023-08-13 |
mouse |
| Yongxiang Li, Lvshuang Chen, Weijie Zhao, Lijuan Sun, Ruixue Zhang, Shuqing Zhu, Kailai Xie, Xiajie Feng, Xin Wu, Zhonghua Sun, Gang Shu, Songbo Wang, Ping Gao, Xiaotong Zhu, Lina Wang, Qingyan Jian. Food reward depends on TLR4 activation in dopaminergic neurons. Pharmacological research. vol 169. 2021-10-04. PMID:33971268. |
conditional deletion of tlr4 also decreased the activity of da neurons while suppressing the expression of tyrosine hydroxylase (th) in the vta, which regulates the concentration of da in the nucleus accumbens (nac) to affect food reward. |
2021-10-04 |
2023-08-13 |
mouse |
| Shruthi A Thomas, David Perekopskiy, Eugene A Kiyatki. Cocaine added to heroin fails to affect heroin-induced brain hypoxia. Brain research. vol 1746. 2021-10-01. PMID:32645379. |
here, we used high-speed amperometry with oxygen sensors to examine changes in oxygen concentrations in the nucleus accumbens (nac) induced by intravenous (iv) cocaine, heroin, and their mixtures in freely-moving rats. |
2021-10-01 |
2023-08-13 |
rat |
| Anna Brancato, Valentina Castelli, Gianluca Lavanco, Giuseppe Tringali, Vincenzo Micale, Martin Kuchar, Cesare D'Amico, Giuseppe Pizzolanti, Salvatore Feo, Carla Cannizzar. Binge-like Alcohol Exposure in Adolescence: Behavioural, Neuroendocrine and Molecular Evidence of Abnormal Neuroplasticity… and Return. Biomedicines. vol 9. issue 9. 2021-10-01. PMID:34572345. |
binge alcohol consumption among adolescents affects the developing neural networks underpinning reward and stress processing in the nucleus accumbens (nac). |
2021-10-01 |
2023-08-13 |
rat |
| Léa Décarie-Spain, Cécile Hryhorczuk, David Lau, Élizabeth Jacob-Brassard, Alexandre Fisette, Stephanie Fulto. Prolonged saturated, but not monounsaturated, high-fat feeding provokes anxiodepressive-like behaviors in female mice despite similar metabolic consequences. Brain, behavior, & immunity - health. vol 16. 2021-10-01. PMID:34589811. |
our group has recently demonstrated a role for nucleus accumbens (nac) pro-inflammatory nuclear factor kappa-b (nfkb) signaling in the development of anxiodepressive-like behaviors by diet-induced obesity in male mice. |
2021-10-01 |
2023-08-13 |
mouse |
| Jun Wang, Yuzhen Zhang, Henghui Zhang, Kewan Wang, Hongxiao Wang, Dadi Qian, Songtao Qi, Kaijun Yang, Hao Lon. Nucleus accumbens shell: A potential target for drug-resistant epilepsy with neuropsychiatric disorders. Epilepsy research. vol 164. 2021-09-30. PMID:32460115. |
the nucleus accumbens (nac) is an important component of the ventral striatum, involving motivational and emotional processes, limbic-motor interfaces. |
2021-09-30 |
2023-08-13 |
Not clear |
| John Drake, Gowon O McMichael, Eric Sean Vornholt, Kellen Cresswell, Vernell Williamson, Chris Chatzinakos, Mohammed Mamdani, Siddharth Hariharan, Kenneth S Kendler, Gursharan Kalsi, Brien P Riley, Mikhail Dozmorov, Michael F Miles, Silviu-Alin Bacanu, Vladimir I Vladimiro. Assessing the Role of Long Noncoding RNA in Nucleus Accumbens in Subjects With Alcohol Dependence. Alcoholism, clinical and experimental research. vol 44. issue 12. 2021-09-29. PMID:33067813. |
thus, we sought to profile lncrna expression in the nucleus accumbens (nac) in a large postmortem alcohol brain sample. |
2021-09-29 |
2023-08-13 |
human |
| Huaqiang Zhu, Dingding Zhuang, Zhongze Lou, Miaojun Lai, Dan Fu, Qingxiao Hong, Huifen Liu, Wenhua Zho. Akt and its phosphorylation in nucleus accumbens mediate heroin-seeking behavior induced by cues in rats. Addiction biology. vol 26. issue 5. 2021-09-29. PMID:33619816. |
here, we aimed to explore the role of p-akt in the nucleus accumbens (nac) in cue-induced heroin-seeking behaviors after withdrawal. |
2021-09-29 |
2023-08-13 |
rat |
| Jonna M Leyrer-Jackson, Lauren E Hood, M Foster Oliv. Alcohol consumption preferentially activates a subset of pro-opiomelanocortin (POMC) producing neurons targeting the amygdala. Neuropharmacology. vol 195. 2021-09-29. PMID:34153315. |
pro-opiomelanocortin (pomc) producing neurons located within the arcuate nucleus (arcn) of the hypothalamus make up one circuit of the endogenous opioid system, and heavily projects to reward-related brain areas such as the amygdala, nucleus accumbens (nac) and ventral tegmental area (vta). |
2021-09-29 |
2023-08-13 |
Not clear |
| Shunji Yamada, Nienke van Kooten, Takuma Mori, Katsutoshi Taguchi, Atsushi Tsujimura, Masaki Tanak. Efferent and Afferent Connections of Neuropeptide Y Neurons in the Nucleus Accumbens of Mice. Frontiers in neuroanatomy. vol 15. 2021-09-29. PMID:34566585. |
we previously reported that npy neurons in the nucleus accumbens (nac) are involved in the regulation of anxiety behavior. |
2021-09-29 |
2023-08-13 |
mouse |
| Hossein Khaleghzadeh-Ahangar, Abbas Haghparas. Cannabinoid receptor modulation changes the accumbal neuronal responses to morphine in the reinstatement of morphine-induced conditioned place preference. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31436887. |
the nucleus accumbens (nac) is a central component of the brain reward system. |
2021-09-28 |
2023-08-13 |
rat |
| Magdalena Sustkova-Fiserova, Nina Puskina, Tereza Havlickova, Marek Lapka, Kamila Syslova, Veronika Pohorala, Chrysostomos Charalambou. Ghrelin receptor antagonism of fentanyl-induced conditioned place preference, intravenous self-administration, and dopamine release in the nucleus accumbens in rats. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31696597. |
therefore, the aim of our study was to clarify whether the ghs-r1a antagonist jmv2959 could reduce the fentanyl-induced conditioned place preference (cpp), the fentanyl intravenous self-administration (ivsa), and the tendency to relapse, but also whether jmv2959 could significantly influence the fentanyl-induced dopamine efflux in the nucleus accumbens (nac) in rats, that importantly participates in opioids' reinforcing effects. |
2021-09-28 |
2023-08-13 |
rat |
| William J Wright, Yan Don. Psychostimulant-Induced Adaptations in Nucleus Accumbens Glutamatergic Transmission. Cold Spring Harbor perspectives in medicine. vol 10. issue 12. 2021-09-28. PMID:31964644. |
carrying different aspects of emotional and motivational signals, glutamatergic synaptic projections from multiple limbic and paralimbic brain regions converge to the nucleus accumbens (nac), in which these arousing signals are processed and prioritized for behavioral output. |
2021-09-28 |
2023-08-13 |
Not clear |
| Zhanglei Dong, Bingwu Huang, Chenchen Jiang, Jiangfan Chen, Han Lin, Qingquan Lian, Binbin W. The Adenosine A2A Receptor Activation in Nucleus Accumbens Suppress Cue-Induced Reinstatement of Propofol Self-administration in Rats. Neurochemical research. vol 46. issue 5. 2021-09-27. PMID:33616808. |
adenosine a2a receptors (a2ar) in the nucleus accumbens (nac) modulate dopamine signal and addictive behaviors such as cocaine- and amphetamine-induced self-administration. |
2021-09-27 |
2023-08-13 |
rat |
| Eric M Parise, Lyonna F Parise, Omar K Sial, Astrid M Cardona-Acosta, Trevonn M Gyles, Barbara Juarez, Dipesh Chaudhury, Ming-Hu Han, Eric J Nestler, Carlos A Bolaños-Guzmá. The Resilient Phenotype Induced by Prophylactic Ketamine Exposure During Adolescence Is Mediated by the Ventral Tegmental Area-Nucleus Accumbens Pathway. Biological psychiatry. vol 90. issue 7. 2021-09-27. PMID:34247781. |
recent evidence showed that ket reverses stress-induced (i.e., depressive-like) deficits within major mesocorticolimbic regions, such as the prefrontal cortex, nucleus accumbens (nac), and hippocampus, in adult rodents. |
2021-09-27 |
2023-08-13 |
Not clear |
| Susanne Nikolaus, Markus Beu, Hans-Jörg Wittsack, Anja Müller-Lutz, Christina Antke, Hubertus Hautzel, Yuriko Mori, Eduards Mamlins, Gerald Antoch, Hans-Wilhelm Mülle. GABAergic and glutamatergic effects on nigrostriatal and mesolimbic dopamine release in the rat. Reviews in the neurosciences. vol 31. issue 6. 2021-09-24. PMID:32619197. |
in these studies, [123i]iodobenzamide binding to the d2/3r was mesured in nucleus accumbens (nac), caudateputamen (cp), substantia nigra/ventral tegmental area (sn/vta), frontal (fc), motor (mc) and parietal cortex (pc) as well as anterior (ahipp) and posterior hippocampus (phipp) with small animal spect in baseline and after injection of either the gabaar agonist muscimol (1 mg/kg), the gabaar antagonist bicuculline (1 mg/kg), the nmdar agonist d-cycloserine (20 mg/kg) or the nmdar antagonist amantadine (40 mg/kg). |
2021-09-24 |
2023-08-13 |
rat |
| Talia Sabran-Cohen, Uri Bright, Tomer Mizrachi Zer-Aviv, Irit Akira. Rapamycin prevents the long-term impairing effects of adolescence Δ-9-tetrahydrocannabinol on memory and plasticity in male rats. The European journal of neuroscience. vol 54. issue 6. 2021-09-24. PMID:34405459. |
thirty days after the last injection, rats were tested for short-term and working memory, anxiety-like behaviour, and plasticity in the pathways projecting from the ventral subiculum (vsub) of the hippocampus to the prefrontal cortex (pfc) and nucleus accumbens (nac). |
2021-09-24 |
2023-08-13 |
rat |
| Claudia Rangel-Barajas, Israel Coronel, Yanping Zhang, Maribel Hernández, Stephen L Boehm I. Low-level developmental lead exposure does not predispose to adult alcohol self-administration, but does increase the risk of relapsing to alcohol seeking in mice: Contrasting role of GLT1 and xCT brain expression. Neuropharmacology. vol 181. 2021-09-23. PMID:33010299. |
because pb exposure is associated with increased glutamatergic tone, we also studied the effects on the expression of synaptic and non-synaptic glutamate transporters in brain regions associated with drug addiction such as the nucleus accumbens (nac), dorsomedial striatum (dms), dorsolateral striatum (dls), and medial prefrontal cortex (mpfc). |
2021-09-23 |
2023-08-13 |
mouse |
| Breanne E Pirino, Mary B Spodnick, Andrew T Gargiulo, Genevieve R Curtis, Jessica R Barson, Anushree N Karkhani. Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis. Neuropharmacology. vol 181. 2021-09-23. PMID:33011200. |
neural circuit engagement within the nucleus accumbens (nac) shell is implicated in the regulation of both negative and positive affect. |
2021-09-23 |
2023-08-13 |
rat |