| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Conversi, C Orsini, S Cabi. Distinct patterns of Fos expression induced by systemic amphetamine in the striatal complex of C57BL/6JICo and DBA/2JICo inbred strains of mice. Brain research. vol 1025. issue 1-2. 2005-01-06. PMID:15464745. |
we used fos expression as a tool to reveal strain differences in the postsynaptic effects of amphetamine (amph; 2.5 mg/kg) within the nucleus accumbens (nac) (core and shell) and the dorsal caudate (dorsomedial and dorsolateral). |
2005-01-06 |
2023-08-12 |
mouse |
| David W Self, Kwang-Ho Choi, Diana Simmons, John R Walker, Cynthia S Smagul. Extinction training regulates neuroadaptive responses to withdrawal from chronic cocaine self-administration. Learning & memory (Cold Spring Harbor, N.Y.). vol 11. issue 5. 2005-01-06. PMID:15466321. |
extinction training normalizes tyrosine hydroxylase levels in the nucleus accumbens (nac) shell, an effect that could help ameliorate dysphoria and depression associated with withdrawal from chronic cocaine use. |
2005-01-06 |
2023-08-12 |
rat |
| Young-Chul Chung, Zhu Li, Jin Dai, Herbert Y Meltzer, Junji Ichikaw. Clozapine increases both acetylcholine and dopamine release in rat ventral hippocampus: role of 5-HT1A receptor agonism. Brain research. vol 1023. issue 1. 2004-12-21. PMID:15364019. |
this advantage has been attributed, in part, to the ability of the atypical apds to markedly increase acetylcholine (ach) and dopamine (da) release in rat medial prefrontal cortex (mpfc), while producing a minimal effect in the nucleus accumbens (nac) or striatum. |
2004-12-21 |
2023-08-12 |
rat |
| David W Sel. Regulation of drug-taking and -seeking behaviors by neuroadaptations in the mesolimbic dopamine system. Neuropharmacology. vol 47 Suppl 1. 2004-12-20. PMID:15464141. |
our studies suggest that drug-induced up-regulation in cyclic amp (camp)-protein kinase a (pka) signaling in the nucleus accumbens (nac) contributes to escalating drug intake and a propensity for relapse by differentially altering the sensitivity of d1 and d2 dopamine receptors that regulate drug-taking and -seeking behaviors. |
2004-12-20 |
2023-08-12 |
Not clear |
| Maria Pia Arolfo, Lina Yao, Adrienne S Gordon, Ivan Diamond, Patricia H Jana. Ethanol operant self-administration in rats is regulated by adenosine A2 receptors. Alcoholism, clinical and experimental research. vol 28. issue 9. 2004-12-16. PMID:15365300. |
recently, we reported that expression of a betagamma inhibitor in the nucleus accumbens (nac) reduces etoh drinking in rats. |
2004-12-16 |
2023-08-12 |
rat |
| Takuro Oka, Takashi Hamamura, Youmei Lee, Shinji Miyata, Toshiaki Habara, Shiro Endo, Hideki Taoka, Shigetoshi Kurod. Atypical properties of several classes of antipsychotic drugs on the basis of differential induction of Fos-like immunoreactivity in the rat brain. Life sciences. vol 76. issue 2. 2004-12-16. PMID:15519367. |
furthermore, atypical index, the difference in the extent of increased fos-like immunoreactivity (fos-li) in the nucleus accumbens (nac) shell versus the dorsolateral striatum (dlst), has been proposed to classify antipsychotics into typical or atypical antipsychotics. |
2004-12-16 |
2023-08-12 |
rat |
| Laurea M Diaz, Rajani Maiya, Matthew A Sullivan, Yunqing Han, Heather A Walton, Stephen L Boehm, Susan E Bergeson, R Dayne Mayfield, Richard A Morriset. Sindbis viral-mediated expression of eGFP-dopamine D1 receptors in situ with real-time two-photon microscopic detection. Journal of neuroscience methods. vol 139. issue 1. 2004-12-15. PMID:15351518. |
parasagittal slice cultures, including the ventral tegmental area (vta) and nucleus accumbens (nac), were infected by manual injection below the glia surface. |
2004-12-15 |
2023-08-12 |
mouse |
| Ute Krügel, Thomas Schraft, Ralph Regenthal, Peter Illes, Holger Kittne. Purinergic modulation of extracellular glutamate levels in the nucleus accumbens in vivo. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 22. issue 7. 2004-12-15. PMID:15465287. |
in the present study, the p2 receptor-mediated modulation of the extracellular glutamate concentration was investigated by microdialysis in the nucleus accumbens (nac) of freely moving rats. |
2004-12-15 |
2023-08-12 |
rat |
| S Klein, M Hadamitzky, M Koch, K Schwab. Role of glutamate receptors in nucleus accumbens core and shell in spatial behaviour of rats. Neuroscience. vol 128. issue 2. 2004-12-09. PMID:15350636. |
the nucleus accumbens (nac) is considered to be an important neural interface between corticolimbic and motor systems of the brain. |
2004-12-09 |
2023-08-12 |
rat |
| Ken T Wakabayashi, Howard L Fields, Saleem M Nicol. Dissociation of the role of nucleus accumbens dopamine in responding to reward-predictive cues and waiting for reward. Behavioural brain research. vol 154. issue 1. 2004-12-08. PMID:15302107. |
dopamine release in the nucleus accumbens (nac) has been suggested to play an important role in cost/benefit computation. |
2004-12-08 |
2023-08-12 |
rat |
| Patricia H Janak, Ming-Teh Chen, Tara Caulde. Dynamics of neural coding in the accumbens during extinction and reinstatement of rewarded behavior. Behavioural brain research. vol 154. issue 1. 2004-12-08. PMID:15302118. |
neural correlates of reward-seeking behavior are observed in the nucleus accumbens (nac). |
2004-12-08 |
2023-08-12 |
human |
| Jouni A Ihalainen, Heikki Tanil. In vivo regulation of dopamine and noradrenaline release by alpha2A-adrenoceptors in the mouse nucleus accumbens. Journal of neurochemistry. vol 91. issue 1. 2004-11-29. PMID:15379886. |
the present study investigated the role of alpha2a-adrenoceptor (alpha2a-ar) subtype in the regulation of noradrenaline (na) and dopamine (da) release in the nucleus accumbens (nac). |
2004-11-29 |
2023-08-12 |
mouse |
| Kerry E Culm, Natasha Lugo-Escobar, Bruce T Hope, Ronald P Hamme. Repeated quinpirole treatment increases cAMP-dependent protein kinase activity and CREB phosphorylation in nucleus accumbens and reverses quinpirole-induced sensorimotor gating deficits in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 10. 2004-11-22. PMID:15138441. |
repeated quinpirole treatment did not alter the levels of basal-, forskolin- (5 microm), or skf 82958- (10 microm) stimulated adenylate cyclase activity in the nucleus accumbens (nac), but significantly increased camp-dependent protein kinase (pka) activity. |
2004-11-22 |
2023-08-12 |
rat |
| Hao-Wei Shen, Yoko Hagino, Hideaki Kobayashi, Keiko Shinohara-Tanaka, Kazutaka Ikeda, Hideko Yamamoto, Toshifumi Yamamoto, Klaus-Peter Lesch, Dennis L Murphy, F Scott Hall, George R Uhl, Ichiro Sor. Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 10. 2004-11-22. PMID:15226739. |
to help determine mechanisms underlying these effects, we now report examination of baselines and drug-induced changes of extracellular dopamine (daex) and serotonin (5-ht(ex)) levels in microdialysates from nucleus accumbens (nac), caudate putamen (cpu), and prefrontal cortex (pfc) of wild-type, homozygous dat- or sert-ko and heterozygous or homozygous dat/sert double-ko mice, which are differentially rewarded by cocaine. |
2004-11-22 |
2023-08-12 |
mouse |
| Akira Nakajima, Kiyofumi Yamada, Jue He, Nan Zeng, Atsumi Nitta, Toshitaka Nabeshim. Anatomical substrates for the discriminative stimulus effects of methamphetamine in rats. Journal of neurochemistry. vol 91. issue 2. 2004-11-15. PMID:15447664. |
fos expression in the brains of rats that discriminate methamphetamine from saline was significantly increased in the nucleus accumbens (nac) and the ventral tegmental area (vta), but not in other areas including the cerebral cortex, caudate putamen, substantia nigra, hippocampus, amygdala and habenulla, as compared with the expression in control rats that were maintained under the fr-20 schedule. |
2004-11-15 |
2023-08-12 |
rat |
| Olivera Pluzarev, Subhash C Pande. Modulation of CREB expression and phosphorylation in the rat nucleus accumbens during nicotine exposure and withdrawal. Journal of neuroscience research. vol 77. issue 6. 2004-11-06. PMID:15334606. |
to understand the molecular mechanisms of nicotine addiction, the present investigation examined the effects of acute and chronic nicotine treatment and its withdrawal on camp-responsive element binding (creb) protein expression and phosphorylation (serine-133) in nucleus accumbens (nac) structures of rats. |
2004-11-06 |
2023-08-12 |
rat |
| Angela J Grippo, Elisa S Na, Ralph F Johnson, Terry G Beltz, Alan Kim Johnso. Sucrose ingestion elicits reduced Fos expression in the nucleus accumbens of anhedonic rats. Brain research. vol 1019. issue 1-2. 2004-11-04. PMID:15306261. |
chronic mild stress (cms), an animal model of depression associated with anhedonia, was used to examine nucleus accumbens (nac) activation associated with a rewarding stimulus. |
2004-11-04 |
2023-08-12 |
rat |
| Remigijus Lape, John A Dan. Complex response to afferent excitatory bursts by nucleus accumbens medium spiny projection neurons. Journal of neurophysiology. vol 92. issue 3. 2004-11-04. PMID:15331641. |
the nucleus accumbens (nac) of the ventral striatum is involved in attention, motivation, movement, learning, reward, and addiction. |
2004-11-04 |
2023-08-12 |
mouse |
| Xiu-Ti Hu, Somnath Basu, Francis J Whit. Repeated cocaine administration suppresses HVA-Ca2+ potentials and enhances activity of K+ channels in rat nucleus accumbens neurons. Journal of neurophysiology. vol 92. issue 3. 2004-11-04. PMID:15331648. |
the nucleus accumbens (nac) is an important forebrain area involved in sensitization, withdrawal effects, and self-administration of cocaine. |
2004-11-04 |
2023-08-12 |
rat |
| Christian P Müller, Heike Thönnessen, Marilia Barros, Carlos Tomaz, Robert J Carey, Joseph P Husto. Hippocampus 5-HT(1A)-receptors attenuate cocaine-induced hyperlocomotion and the increase in hippocampal but not nucleus accumbens 5-HT. Hippocampus. vol 14. issue 6. 2004-11-01. PMID:15318330. |
cocaine induces an increase in hippocampal and nucleus accumbens (nac) serotonin (5-ht) concentration parallel to locomotor activation. |
2004-11-01 |
2023-08-12 |
rat |