| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrew M J Young, Paula M Moran, Michael H Josep. The role of dopamine in conditioning and latent inhibition: what, when, where and how? Neuroscience and biobehavioral reviews. vol 29. issue 6. 2005-10-27. PMID:16045987. |
it is well established that dopamine is released in the nucleus accumbens (nac) in animals in rewarding or reinforcing situations, and widely believed that this release is the substrate of, or at least closely related to, the experience of reward. |
2005-10-27 |
2023-08-12 |
Not clear |
| Junji Ichikawa, Young-Chul Chung, Jin Dai, Herbert Y Meltze. Valproic acid potentiates both typical and atypical antipsychotic-induced prefrontal cortical dopamine release. Brain research. vol 1052. issue 1. 2005-10-27. PMID:16061211. |
vpa (50 mg/kg), which was insufficient by itself to increase prefrontal cortical da release, potentiated the ability of clozapine (20 mg/kg) and risperidone (1 mg/kg) to increase da release in the mpfc, but not in the nucleus accumbens (nac). |
2005-10-27 |
2023-08-12 |
rat |
| Todor V Gerdjikov, Richard J Beninge. Differential effects of calcineurin inhibition and protein kinase A activation on nucleus accumbens amphetamine-produced conditioned place preference in rats. The European journal of neuroscience. vol 22. issue 3. 2005-10-27. PMID:16101751. |
the nucleus accumbens (nac) plays a critical role in amphetamine-produced conditioned place preference (cpp). |
2005-10-27 |
2023-08-12 |
rat |
| Xuebing Liu, Yi Li, Liang Zhou, Hongxian Chen, Zhonghua Su, Wei Ha. Conditioned place preference associates with the mRNA expression of diazepam binding inhibitor in brain regions of the addicted rat during withdrawal. Brain research. Molecular brain research. vol 137. issue 1-2. 2005-09-19. PMID:15950760. |
remarkably, the dbi mrna expressions in the ca1 region of the hippocampus (ca1), ventral tagmental area (vta), nucleus accumbens (nac) and amygdala (amg) were positively correlated to cpp during the periods from withdrawal for 3 days to withdrawal for 6 days. |
2005-09-19 |
2023-08-12 |
rat |
| Daniel G Smith, Eleni T Tzavara, Janice Shaw, Susan Luecke, Mark Wade, Richard Davis, Craig Salhoff, George G Nomikos, Donald R Gehler. Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 4. 2005-08-31. PMID:15673672. |
melanin-concentrating hormone (mch) neurons and mch-1 receptors (mch1r) densely populate mesolimbic dopaminergic brain regions such as the nucleus accumbens (nac). |
2005-08-31 |
2023-08-12 |
mouse |
| Rejean M Guerriero, Anjali Rajadhyaksha, Claire Crozatier, Bruno Giros, Marika Nosten-Bertrand, Barry E Kosofsk. Augmented constitutive CREB expression in the nucleus accumbens and striatum may contribute to the altered behavioral response to cocaine of adult mice exposed to cocaine in utero. Developmental neuroscience. vol 27. issue 2-4. 2005-08-25. PMID:16046859. |
tissue samples of the nucleus accumbens (nac) and striatum (str) of all four prenatal treatment groups were examined to determine whether alterations in the transcription factor creb or glutamate receptor subunit, glur1, induced by prenatal cocaine treatment may have contributed to the altered behavioral responses. |
2005-08-25 |
2023-08-12 |
mouse |
| Robert C Risinger, Betty Jo Salmeron, Thomas J Ross, Shelley L Amen, Michael Sanfilipo, Raymond G Hoffmann, Alan S Bloom, Hugh Garavan, Elliot A Stei. Neural correlates of high and craving during cocaine self-administration using BOLD fMRI. NeuroImage. vol 26. issue 4. 2005-08-23. PMID:15886020. |
drug-induced high was found to correlate negatively with activity in limbic, paralimbic, and mesocortical regions including the nucleus accumbens (nac), inferior frontal/orbitofrontal gyrus (ofc), and anterior cingulate (ac), while craving correlated positively with activity in these regions. |
2005-08-23 |
2023-08-12 |
human |
| Lina Yao, Krista McFarland, Peidong Fan, Zhan Jiang, Yuichiro Inoue, Ivan Diamon. Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 24. 2005-08-16. PMID:15937104. |
the nucleus accumbens (nac) is central to heroin addiction. |
2005-08-16 |
2023-08-12 |
human |
| W M Freeman, K Brebner, S G Amara, M S Reed, J Pohl, A G Phillip. Distinct proteomic profiles of amphetamine self-administration transitional states. The pharmacogenomics journal. vol 5. issue 3. 2005-08-12. PMID:15852055. |
stimulation of the ventral subiculum (vsub) during voluntary abstinence from d-amph self-administration reinstates self-administration and increases nucleus accumbens (nac) dopamine efflux. |
2005-08-12 |
2023-08-12 |
rat |
| S L Haberny, K D Car. Food restriction increases NMDA receptor-mediated calcium-calmodulin kinase II and NMDA receptor/extracellular signal-regulated kinase 1/2-mediated cyclic amp response element-binding protein phosphorylation in nucleus accumbens upon D-1 dopamine receptor stimulation in rats. Neuroscience. vol 132. issue 4. 2005-08-03. PMID:15857708. |
the main purpose of the present study was to characterize the involvement and mechanisms of interaction between nmda receptor function and the augmented cellular responses to d-1 da receptor stimulation in nucleus accumbens (nac) of fr rats. |
2005-08-03 |
2023-08-12 |
human |
| Catharine A Winstanley, David E H Theobald, Jeffrey W Dalley, Trevor W Robbin. Interactions between serotonin and dopamine in the control of impulsive choice in rats: therapeutic implications for impulse control disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 4. 2005-07-28. PMID:15688093. |
nucleus accumbens (nac) lesions increase impulsivity, but the extent to which accumbal da is involved in regulating impulsive choice is unknown. |
2005-07-28 |
2023-08-12 |
human |
| Pepe J Hernandez, Matthew E Andrzejewski, Kenneth Sadeghian, Jules B Panksepp, Ann E Kelle. AMPA/kainate, NMDA, and dopamine D1 receptor function in the nucleus accumbens core: a context-limited role in the encoding and consolidation of instrumental memory. Learning & memory (Cold Spring Harbor, N.Y.). vol 12. issue 3. 2005-07-27. PMID:15930507. |
neural integration of glutamate- and dopamine-coded signals within the nucleus accumbens (nac) is a fundamental process governing cellular plasticity underlying reward-related learning. |
2005-07-27 |
2023-08-12 |
rat |
| Ryan T LaLumiere, Erene M Nawar, James L McGaug. Modulation of memory consolidation by the basolateral amygdala or nucleus accumbens shell requires concurrent dopamine receptor activation in both brain regions. Learning & memory (Cold Spring Harbor, N.Y.). vol 12. issue 3. 2005-07-27. PMID:15930508. |
previous findings indicate that the basolateral amygdala (bla) and the nucleus accumbens (nac) interact in influencing memory consolidation. |
2005-07-27 |
2023-08-12 |
rat |
| Jeffrey W Dalley, Kristjan Lääne, David E H Theobald, Hannah C Armstrong, Philip R Corlett, Yogita Chudasama, Trevor W Robbin. Time-limited modulation of appetitive Pavlovian memory by D1 and NMDA receptors in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 17. 2005-07-08. PMID:15833811. |
recent research has implicated the nucleus accumbens (nac) in consolidating recently acquired goal-directed appetitive memories, including spatial learning and other instrumental processes. |
2005-07-08 |
2023-08-12 |
rat |
| Linda I Perrotti, Yuki Hadeishi, Paula G Ulery, Michel Barrot, Lisa Monteggia, Ronald S Duman, Eric J Nestle. Induction of deltaFosB in reward-related brain structures after chronic stress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 47. 2005-07-05. PMID:15564575. |
western blotting, using an antibody that recognizes all fos family members, revealed that acute restraint stress caused robust induction of c-fos and full-length fosb, as well as a small induction of deltafosb, in the frontal cortex (fctx) and nucleus accumbens (nac). |
2005-07-05 |
2023-08-12 |
Not clear |
| Elena Butovsky, Ana Juknat, Igor Goncharov, Judith Elbaz, Raya Eilam, Abraham Zangen, Zvi Voge. In vivo up-regulation of brain-derived neurotrophic factor in specific brain areas by chronic exposure to Delta-tetrahydrocannabinol. Journal of neurochemistry. vol 93. issue 4. 2005-07-05. PMID:15857384. |
real-time pcr revealed a 10-fold up-regulation of bdnf mrna in the nucleus accumbens (nac) upon chronic delta(9)-thc treatment, but there was no change at 3 or 24 h after a single injection. |
2005-07-05 |
2023-08-12 |
rat |
| Anthony D Miller, Charles D Blah. Midbrain muscarinic receptor mechanisms underlying regulation of mesoaccumbens and nigrostriatal dopaminergic transmission in the rat. The European journal of neuroscience. vol 21. issue 7. 2005-07-05. PMID:15869479. |
the present study investigated the role of midbrain muscarinic receptors in the functional modulation of vta and snc dopamine cell activity as reflected by alterations in, respectively, nucleus accumbens (nac) and striataldopamine efflux. |
2005-07-05 |
2023-08-12 |
rat |
| Isabel Schwienbacher, Markus Fendt, Hans-Ulrich Schnitzle. Amphetamine injections into the nucleus accumbens affect neither acquisition/expression of conditioned fear nor baseline startle response. Experimental brain research. vol 160. issue 4. 2005-06-30. PMID:15650891. |
we therefore injected the dopamine agonist amphetamine into the nucleus accumbens (nac) immediately before either acquisition or expression of conditioned fear and measured the effect of these injections on fear-potentiated startle and baseline startle response. |
2005-06-30 |
2023-08-12 |
Not clear |
| Taku Nagai, Hiroyuki Kamei, Mina Ito, Kazuki Hashimoto, Kazuhiro Takuma, Toshitaka Nabeshima, Kiyofumi Yamad. Modification by the tissue plasminogen activator-plasmin system of morphine-induced dopamine release and hyperlocomotion, but not anti-nociceptive effect in mice. Journal of neurochemistry. vol 93. issue 5. 2005-06-24. PMID:15948318. |
we have recently demonstrated that the tpa-plasmin system participates in the rewarding and locomotor-stimulating effects of morphine by acutely regulating morphine-induced dopamine release in the nucleus accumbens (nac). |
2005-06-24 |
2023-08-12 |
mouse |
| Samuel B Kombian, Kethireddy V V Ananthalakshmi, Subramanian S Parvathy, Wandikayi C Matow. Cholecystokinin inhibits evoked inhibitory postsynaptic currents in the rat nucleus accumbens indirectly through gamma-aminobutyric acid and gamma-aminobutyric acid type B receptors. Journal of neuroscience research. vol 79. issue 3. 2005-06-10. PMID:15605383. |
we recently reported that cholecystokinin (cck) excited nucleus accumbens (nac) cells and depressed excitatory synaptic transmission indirectly through gamma-aminobutyric acid (gaba), acting on presynaptic gabab receptors (kombian et al. |
2005-06-10 |
2023-08-12 |
rat |