| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Panayotis K Thanos, Seth N Rivera, Katrina Weaver, David K Grandy, Marcelo Rubinstein, Hiroyuki Umegaki, Gene Jack Wang, Robert Hitzemann, Nora D Volko. Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking. Life sciences. vol 77. issue 2. 2005-06-02. PMID:15862598. |
previous studies have shown that d2r upregulation in the nucleus accumbens (nac) attenuated alcohol consumption. |
2005-06-02 |
2023-08-12 |
mouse |
| Michael G Bankson, Bryan K Yamamot. Serotonin-GABA interactions modulate MDMA-induced mesolimbic dopamine release. Journal of neurochemistry. vol 91. issue 4. 2005-05-25. PMID:15525339. |
the present study used microdialysis in awake rats to measure mdma-induced changes in extracellular gaba in the ventral tegmental area (vta), simultaneous with measures of extracellular dopamine (da) in the nucleus accumbens (nac) shell. |
2005-05-25 |
2023-08-12 |
rat |
| b' Davide Quarta, Janusz Borycz, Marcello Solinas, Kshitij Patkar, J\\xc3\\xb6rg Hockemeyer, Francisco Ciruela, Carme Lluis, Rafael Franco, Amina S Woods, Steven R Goldberg, Sergi Ferr\\xc3\\xa. Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-D-aspartate receptor stimulation. Journal of neurochemistry. vol 91. issue 4. 2005-05-25. PMID:15525341.' |
by using in vivo microdialysis techniques, local perfusion of nmda (3, 10 microm), the selective a(2a) receptor agonist 2-p-(2-carboxyethyl)phenethylamino-5'-n-ethylcarboxamidoadenosine (cgs 21680; 3, 10 microm), the selective a(1) receptor antagonist 8-cyclopentyl-1,3-dimethylxanthine (cpt; 300, 1000 microm), or the non-selective a(1)-a(2a) receptor antagonist in vitro caffeine (300, 1000 microm) elicited significant increases in extracellular levels of dopamine in the shell of the nucleus accumbens (nac). |
2005-05-25 |
2023-08-12 |
Not clear |
| Anna Molander, Bo Söderpal. Accumbal strychnine-sensitive glycine receptors: an access point for ethanol to the brain reward system. Alcoholism, clinical and experimental research. vol 29. issue 1. 2005-05-25. PMID:15654288. |
ethanol (etoh), like other drugs of abuse, increases extracellular dopamine (da) levels in the nucleus accumbens (nac) of the brain reward system, an effect that may be of importance for alcohol addiction. |
2005-05-25 |
2023-08-12 |
Not clear |
| Anna Molander, Elin Löf, Rosita Stomberg, Mia Ericson, Bo Söderpal. Involvement of accumbal glycine receptors in the regulation of voluntary ethanol intake in the rat. Alcoholism, clinical and experimental research. vol 29. issue 1. 2005-05-25. PMID:15654289. |
extracellular dopamine (da) levels in the nucleus accumbens (nac) increase after ethanol (etoh) administration in the rat, a response that may be involved in the positive reinforcing effects of etoh. |
2005-05-25 |
2023-08-12 |
rat |
| Edwin H Jacobs, August B Smit, Taco J de Vries, Anton N M Schoffelmee. Long-term gene expression in the nucleus accumbens following heroin administration is subregion-specific and depends on the nature of drug administration. Addiction biology. vol 10. issue 1. 2005-05-19. PMID:15849023. |
within this system, the nucleus accumbens (nac) plays a major integrative role. |
2005-05-19 |
2023-08-12 |
rat |
| Carrie L Walters, Misty Godfrey, Xiao Li, Julie A Blend. Alterations in morphine-induced reward, locomotor activity, and thermoregulation in CREB-deficient mice. Brain research. vol 1032. issue 1-2. 2005-05-12. PMID:15680959. |
the behavioral differences in response to morphine seen in creb(alphadelta) mutant mice are not due to changes in mu opioid receptor (mor) mrna expression, as the creb deletion has no effect on baseline mor mrna in three of the brain regions involved in mediating these behaviors: the ventral tegmental area (vta), nucleus accumbens (nac), and hypothalamus. |
2005-05-12 |
2023-08-12 |
mouse |
| Teodoro Zornoza, María J Cano-Cebrián, Marta Miquel, Carlos Aragón, Ana Polache, Luis Graner. Hippocampal dopamine receptors modulate the motor activation and the increase in dopamine levels in the rat nucleus accumbens evoked by chemical stimulation of the ventral hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 5. 2005-05-12. PMID:15689964. |
a number of studies have shown that chemical stimulation (using n-methyl-d-aspartate (nmda) infusions) or electrical stimulation of the ventral hippocampus (vh) elicits locomotor activation and sustained increases in nucleus accumbens (nac) dopamine (da) levels in rodents. |
2005-05-12 |
2023-08-12 |
rat |
| Xiu-Ti Hu, Kerstin Ford, Francis J Whit. Repeated cocaine administration decreases calcineurin (PP2B) but enhances DARPP-32 modulation of sodium currents in rat nucleus accumbens neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 5. 2005-05-12. PMID:15726118. |
our previous studies have demonstrated that repeated cocaine (coc) administration reduces voltage-sensitive sodium and calcium currents (i(na) or vsscs and i(ca) or vsccs, respectively) in medium spiny nucleus accumbens (nac) neurons of rats. |
2005-05-12 |
2023-08-12 |
rat |
| M Pistis, A L Muntoni, G Pillolla, S Perra, G Cignarella, M Melis, G L Gess. Gamma-hydroxybutyric acid (GHB) and the mesoaccumbens reward circuit: evidence for GABA(B) receptor-mediated effects. Neuroscience. vol 131. issue 2. 2005-05-03. PMID:15708487. |
drugs of abuse exert remarkably similar effects upon reward-related circuits, in particular the mesolimbic dopaminergic system and the nucleus accumbens (nac). |
2005-05-03 |
2023-08-12 |
rat |
| Xiu-Ti Hu, Yan Dong, Xu-Feng Zhang, Francis J Whit. Dopamine D2 receptor-activated Ca2+ signaling modulates voltage-sensitive sodium currents in rat nucleus accumbens neurons. Journal of neurophysiology. vol 93. issue 3. 2005-05-02. PMID:15590733. |
receptor-mediated dopamine (da) modulation of neuronal excitability in the nucleus accumbens (nac) has been shown to be critically involved in drug addiction and a variety of brain diseases. |
2005-05-02 |
2023-08-12 |
rat |
| P Rada, D F Johnson, M J Lewis, B G Hoebe. In alcohol-treated rats, naloxone decreases extracellular dopamine and increases acetylcholine in the nucleus accumbens: evidence of opioid withdrawal. Pharmacology, biochemistry, and behavior. vol 79. issue 4. 2005-04-29. PMID:15582668. |
as with the withdrawal from morphine, nicotine, diazepam and sugar, the ethanol withdrawal state may involve an increase in nucleus accumbens (nac) acetylcholine (ach) causing an alteration of the dopamine (da)-ach balance in favor of ach. |
2005-04-29 |
2023-08-12 |
rat |
| David W Self, Kwang-Ho Cho. Extinction-induced neuroplasticity attenuates stress-induced cocaine seeking: a state-dependent learning hypothesis. Stress (Amsterdam, Netherlands). vol 7. issue 3. 2005-04-28. PMID:15764012. |
chronic drug use weakens excitatory neocortical input to the nucleus accumbens (nac). |
2005-04-28 |
2023-08-12 |
Not clear |
| Mitchell F Roitman, Robert A Wheeler, Regina M Carell. Nucleus accumbens neurons are innately tuned for rewarding and aversive taste stimuli, encode their predictors, and are linked to motor output. Neuron. vol 45. issue 4. 2005-04-25. PMID:15721244. |
the nucleus accumbens (nac) is a key component of the brain's reward pathway, yet little is known of how nac cells respond to primary rewarding or aversive stimuli. |
2005-04-25 |
2023-08-12 |
rat |
| Carl R Lupica, Arthur C Riegel, Alexander F Hoffma. Marijuana and cannabinoid regulation of brain reward circuits. British journal of pharmacology. vol 143. issue 2. 2005-04-22. PMID:15313883. |
of these brain regions, the ventral tegmental area (vta) and the nucleus accumbens (nac) play central roles in the processing of rewarding environmental stimuli and in drug addiction. |
2005-04-22 |
2023-08-12 |
Not clear |
| Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, Taketoshi On. Dopamine D1 receptors involved in locomotor activity and accumbens neural responses to prediction of reward associated with place. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 6. 2005-04-22. PMID:15684065. |
the nucleus accumbens (nac) receives converging inputs from corticolimbic information-processing areas and from mesolimbic dopamine neurons originating in the ventral tegmental area. |
2005-04-22 |
2023-08-12 |
mouse |
| Gregory O Hjelmsta. Dopamine excites nucleus accumbens neurons through the differential modulation of glutamate and GABA release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 39. 2005-04-14. PMID:15456835. |
afferent activity into the nucleus accumbens (nac) occurs in bursts of action potentials. |
2005-04-14 |
2023-08-12 |
rat |
| Pei Fei Gu, Jing Yu Yang, Chun Fu Wu, Wei Li, Yu Shan. Frontal decortication eliminates drug-induced ascorbic acid release in the striatum but not the nucleus accumbens of freely moving rats. Brain research. vol 1033. issue 2. 2005-04-13. PMID:15694924. |
the mechanism of morphine-, methamphetamine-, and nicotine-induced ascorbic acid (aa) release in the striatum and nucleus accumbens (nac) is not well understood. |
2005-04-13 |
2023-08-12 |
rat |
| Yolanda Mateo, Evgeny A Budygin, Carrie E John, Matthew L Banks, Sara R Jone. Voltammetric assessment of dopamine clearance in the absence of the dopamine transporter: no contribution of other transporters in core or shell of nucleus accumbens. Journal of neuroscience methods. vol 140. issue 1-2. 2005-04-12. PMID:15589348. |
cocaine elevates dopamine (da) in the nucleus accumbens (nac) by blocking the uptake of da through the da transporter (dat). |
2005-04-12 |
2023-08-12 |
mouse |
| Anita J Bechtholt, Christopher L Cunningha. Ethanol-induced conditioned place preference is expressed through a ventral tegmental area dependent mechanism. Behavioral neuroscience. vol 119. issue 1. 2005-04-12. PMID:15727526. |
the authors examined the role of the ventral tegmental area (vta) and nucleus accumbens (nac) in the expression of ethanol-induced conditioned place preference (cpp). |
2005-04-12 |
2023-08-12 |
mouse |