| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stan B Floresco, Sarvin Ghods-Sharifi, Claudia Vexelman, Orsolya Magya. Dissociable roles for the nucleus accumbens core and shell in regulating set shifting. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 9. 2006-04-11. PMID:16510723. |
the present study investigated the role of two major efferents of the prefrontal cortex, the nucleus accumbens (nac) core and shell, in behavioral flexibility using a maze-based strategy set-shifting task. |
2006-04-11 |
2023-08-12 |
rat |
| Guojun Chen, Josef T Kittler, Stephen J Moss, Zhen Ya. Dopamine D3 receptors regulate GABAA receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 9. 2006-04-11. PMID:16510729. |
the dopamine d3 receptor, which is highly enriched in nucleus accumbens (nac), has been suggested to play an important role in reinforcement and reward. |
2006-04-11 |
2023-08-12 |
Not clear |
| V I Chefer, T S Shippenber. Paradoxical effects of prodynorphin gene deletion on basal and cocaine-evoked dopaminergic neurotransmission in the nucleus accumbens. The European journal of neuroscience. vol 23. issue 1. 2006-04-06. PMID:16420432. |
quantitative and conventional microdialysis were used to investigate the effects of constitutive deletion of the prodynorphin gene on basal dopamine (da) dynamics in the nucleus accumbens (nac) and the responsiveness of da neurons to an acute cocaine challenge. |
2006-04-06 |
2023-08-12 |
mouse |
| Taylor Moran-Gates, Lu Gan, Young Shik Park, Kehong Zhang, Ross J Baldessarini, Frank I Taraz. Repeated antipsychotic drug exposure in developing rats: dopamine receptor effects. Synapse (New York, N.Y.). vol 59. issue 2. 2006-04-05. PMID:16270300. |
fluphenazine and olanzapine, but not clozapine, also increased d2 receptor levels in hippocampus, and d4 levels in nucleus accumbens (nac) and caudate-putamen (cpu) in both juvenile and adult brain. |
2006-04-05 |
2023-08-12 |
rat |
| Regina M Carelli, Joyce Wondolowsk. Anatomic distribution of reinforcer selective cell firing in the core and shell of the nucleus accumbens. Synapse (New York, N.Y.). vol 59. issue 2. 2006-04-05. PMID:16270303. |
we have previously reported that distinct populations of nucleus accumbens (nac) neurons differentially encode information about goal-directed behaviors for "natural" (food/water) vs. cocaine reinforcement [j neurosci 20:4255-4266, (2000)]. |
2006-04-05 |
2023-08-12 |
rat |
| Patrick N Augustyniak, Said Kourrich, Shohreh M Rezazadeh, Jane Stewart, Andreas Arvanitogianni. Differential behavioral and neurochemical effects of cocaine after early exposure to methylphenidate in an animal model of attention deficit hyperactivity disorder. Behavioural brain research. vol 167. issue 2. 2006-04-04. PMID:16246436. |
we used a putative animal model of attention deficit hyperactivity disorder (adhd), the shr rat, to examine the effects of repeated exposure to methylphenidate (mph; ritalin) during the pubertal period on cocaine-induced conditioned place preference and dopamine (da) levels in the nucleus accumbens (nac) in adulthood. |
2006-04-04 |
2023-08-12 |
rat |
| William A Carlezon, Cécile Béguin, Jennifer A DiNieri, Michael H Baumann, Michele R Richards, Mark S Todtenkopf, Richard B Rothman, Zhongze Ma, David Y-W Lee, Bruce M Cohe. Depressive-like effects of the kappa-opioid receptor agonist salvinorin A on behavior and neurochemistry in rats. The Journal of pharmacology and experimental therapeutics. vol 316. issue 1. 2006-03-31. PMID:16223871. |
at a dose that caused the depressive-like effects in both the fst and icss assays, salva decreased extracellular concentrations of dopamine (da) within the nucleus accumbens (nac), a critical component of brain reward circuitry, without affecting extracellular concentrations of serotonin (5-ht). |
2006-03-31 |
2023-08-12 |
rat |
| Eleftherios G Pallis, Christina Spyraki, Kyriaki Thermo. Chronic antidepressant treatment modulates the release of somatostatin in the rat nucleus accumbens. Neuroscience letters. vol 395. issue 1. 2006-03-29. PMID:16293366. |
this study investigated the in vivo neuronal release of somatostatin in the rat nucleus accumbens (nac), and the effect of chronic administration of antidepressants. |
2006-03-29 |
2023-08-12 |
rat |
| Venetia Zachariou, Carlos A Bolanos, Dana E Selley, David Theobald, Michael P Cassidy, Max B Kelz, Tamara Shaw-Lutchman, Olivier Berton, Laura J Sim-Selley, Ralph J Dileone, Arvind Kumar, Eric J Nestle. An essential role for DeltaFosB in the nucleus accumbens in morphine action. Nature neuroscience. vol 9. issue 2. 2006-03-29. PMID:16415864. |
the transcription factor deltafosb is induced in the nucleus accumbens (nac) and dorsal striatum by the repeated administration of drugs of abuse. |
2006-03-29 |
2023-08-12 |
mouse |
| Natalia Omelchenko, Susan R Sesac. Cholinergic axons in the rat ventral tegmental area synapse preferentially onto mesoaccumbens dopamine neurons. The Journal of comparative neurology. vol 494. issue 6. 2006-03-27. PMID:16385486. |
these actions are believed to involve connections with dopamine (da) neurons projecting to the nucleus accumbens (nac). |
2006-03-27 |
2023-08-12 |
rat |
| Eric A Engleman, Cynthia M Ingraham, Caryn E O'Brien, William J McBride, James M Murph. Effect of housing conditions on sulpiride-induced increases in extracellular dopamine (DA) levels in the nucleus accumbens of alcohol-preferring (P) rats. Brain research. vol 1022. issue 1-2. 2006-03-23. PMID:15353236. |
the effect of housing conditions on sulpiride-induced increases in extracellular dopamine (da) levels was investigated in the nucleus accumbens (nac) of p rats. |
2006-03-23 |
2023-08-12 |
rat |
| Sandra L Haberny, Kenneth D Car. Comparison of basal and D-1 dopamine receptor agonist-stimulated neuropeptide gene expression in caudate-putamen and nucleus accumbens of ad libitum fed and food-restricted rats. Brain research. Molecular brain research. vol 141. issue 2. 2006-03-21. PMID:16257473. |
results indicate that, in nucleus accumbens (nac), basal levels of ppd and preprotachykinin (ppt) mrna are lower in fr than al rats. |
2006-03-21 |
2023-08-12 |
human |
| Jun-ichi Karasawa, Takao Yoshimizu, Shigeyuki Chak. A metabotropic glutamate 2/3 receptor antagonist, MGS0039, increases extracellular dopamine levels in the nucleus accumbens shell. Neuroscience letters. vol 393. issue 2-3. 2006-03-14. PMID:16233956. |
in the present study, we examined the effect of mgs0039 on extracellular dopamine levels in the rat nucleus accumbens (nac) shell using in vivo microdialysis evaluation because accumbal dopamine has been implicated in depression. |
2006-03-14 |
2023-08-12 |
rat |
| Yan Pan, Ermanda Siregar, Kenneth D Car. Striatal cell signaling in chronically food-restricted rats under basal conditions and in response to brief handling. Neuroscience letters. vol 393. issue 2-3. 2006-03-14. PMID:16239070. |
specifically, d-1 dopamine (da) receptor agonist challenge produced stronger activation of extracellular signal-regulated kinase (erk), calcium-calmodulin-dependent kinase ii (camkii), and the nuclear transcription factor camp response element binding protein (creb) in nucleus accumbens (nac) of food-restricted (fr) relative to ad libitum fed (al) rats. |
2006-03-14 |
2023-08-12 |
human |
| Eugene D Festa, Shirzad Jenab, Jan Weiner, Arbi Nazarian, Tipyamol Niyomchai, Scott J Russo, Lynne M Kemen, Alaleh Akhavan, Hui-Bing K Wu, Vanya Quinones-Jena. Cocaine-induced sex differences in D1 receptor activation and binding levels after acute cocaine administration. Brain research bulletin. vol 68. issue 4. 2006-03-08. PMID:16377433. |
there were no sex differences in baseline levels of d1, d2, and da transporter binding in the caudate putamen (cpu) and the nucleus accumbens (nac). |
2006-03-08 |
2023-08-12 |
rat |
| Zachary N Stowe, Jacque C Landry, Zhongliang Tang, Michael J Owens, Becky Kinkead, Charles B Nemerof. The electrophysiological effects of neurotensin on spontaneously active neurons in the nucleus accumbens: an in vivo study. Synapse (New York, N.Y.). vol 58. issue 3. 2006-02-24. PMID:16108007. |
the electrophysiological effects of nt were studied using extracellular recording techniques and iontophoretic application in 243 spontaneously active neurons in the nucleus accumbens (nac), with a positive/negative waveform. |
2006-02-24 |
2023-08-12 |
Not clear |
| Jörg Lesting, Jörg Neddens, Gertraud Teuchert-Nood. Ontogeny of the dopamine innervation in the nucleus accumbens of gerbils. Brain research. vol 1066. issue 1-2. 2006-02-15. PMID:16343448. |
the postnatal maturation of immunohistochemically stained dopamine (da) fibres was quantitatively examined in the core and shell subareas of the nucleus accumbens (nac) of gerbils. |
2006-02-15 |
2023-08-12 |
Not clear |
| Y R Fang, T Abekawa, X B Li, Z C Wang, T Inoue, T Koyam. Effect of the protein kinase C inhibitor, staurosporine, on the high dose of methamphetamine-induced behavioral sensitization to dizocilpine (MK-801). Psychopharmacology. vol 180. issue 1. 2006-02-13. PMID:15682296. |
in our preliminary study, methamphetamine (meth) at 2.5 mg/kg, but not at 1.0 mg/kg, induced a delayed increase in glutamate levels in the nucleus accumbens (nac). |
2006-02-13 |
2023-08-12 |
Not clear |
| I Aharon, L Becerra, L Becerraa, C F Chabris, D Borsook, D Borsook. Noxious heat induces fMRI activation in two anatomically distinct clusters within the nucleus accumbens. Neuroscience letters. vol 392. issue 3. 2006-02-07. PMID:16257488. |
using functional magnetic resonance imaging (fmri) we found that a noxious thermal stimulus (46 degrees c) to the hand activates the nucleus accumbens (nac) in humans, while a non-noxious warm stimulus (41 degrees c) does not. |
2006-02-07 |
2023-08-12 |
Not clear |
| Mayumi Fujio, Takayuki Nakagawa, Yumiko Sekiya, Tohru Ozawa, Yuichi Suzuki, Masabumi Minami, Masamichi Satoh, Shuji Kanek. Gene transfer of GLT-1, a glutamate transporter, into the nucleus accumbens shell attenuates methamphetamine- and morphine-induced conditioned place preference in rats. The European journal of neuroscience. vol 22. issue 11. 2006-02-07. PMID:16324108. |
several lines of evidence have suggested that the glutamatergic system in the nucleus accumbens (nac) plays an important role in the conditioned rewarding effect of drugs of abuse. |
2006-02-07 |
2023-08-12 |
mouse |