| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer M Bossert, Sarah M Gray, Lin Lu, Yavin Shaha. Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16341024. |
here, we tested whether injections of ly379268 into the nucleus accumbens (nac), a terminal region of the mesolimbic dopamine system, would also attenuate context-induced reinstatement of heroin seeking. |
2006-11-01 |
2023-08-12 |
rat |
| Jesse R Schank, Rossella Ventura, Stefano Puglisi-Allegra, Antonio Alcaro, Charlene D Cole, L Cameron Liles, Philip Seeman, David Weinshenke. Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16395294. |
basal extracellular da levels were significantly attenuated in the nucleus accumbens (nac) and caudate putamen (cp), but not prefrontal cortex (pfc), of dbh-/- mice, while amphetamine-induced da release was absent in the nac and attenuated in the cp and pfc. |
2006-11-01 |
2023-08-12 |
mouse |
| Taylor Moran-Gates, Carla Massari, Amaury Graulich, Jean-François Liégeois, Frank I Taraz. Long-term effects of JL 13, a potential atypical antipsychotic, on rat dopamine and serotonin receptor subtypes. Journal of neuroscience research. vol 84. issue 3. 2006-11-01. PMID:16810690. |
similar to other typical and atypical antipsychotics, jl 13 increased labeling of d(2) receptors in medial prefrontal cortex (mpc) and hippocampus (hip) and d(4) receptors in nucleus accumbens (nac), caudate-putamen (cpu), and hip. |
2006-11-01 |
2023-08-12 |
rat |
| Ashley Acheson, Andrew M Farrar, Michele Patak, Kathryn A Hausknecht, Artur K Kieres, Seulgi Choi, Harriet de Wit, Jerry B Richard. Nucleus accumbens lesions decrease sensitivity to rapid changes in the delay to reinforcement. Behavioural brain research. vol 173. issue 2. 2006-11-01. PMID:16884790. |
to investigate the neural mechanisms that mediate delay discounting, the present study examined the effects of excitotoxic lesions of the nucleus accumbens (nac) on discounting of reward value by delay and probability. |
2006-11-01 |
2023-08-12 |
rat |
| Gregg D Stanwood, Joshua P Parlaman, Pat Levit. Genetic or pharmacological inactivation of the dopamine D1 receptor differentially alters the expression of regulator of G-protein signalling (Rgs) transcripts. The European journal of neuroscience. vol 24. issue 3. 2006-11-01. PMID:16930410. |
these changes were confirmed by in situ hybridization, and were also observed in the nucleus accumbens (nac). |
2006-11-01 |
2023-08-12 |
mouse |
| Wei Xiong, Long-Chuan Y. Involvement of endogenous cholecystokinin in tolerance to morphine antinociception in the nucleus accumbens of rats. Behavioural brain research. vol 173. issue 1. 2006-10-12. PMID:16837074. |
the present study investigated the effects of endogenous cck on tolerance to morphine antinociception in the nucleus accumbens (nac) of rats. |
2006-10-12 |
2023-08-12 |
rat |
| Tanja Vihavainen, Jelena Mijatovic, T Petteri Piepponen, Raimo K Tuominen, Liisa Ahte. Effect of morphine on locomotor activity and striatal monoamine metabolism in nicotine-withdrawn mice. Behavioural brain research. vol 173. issue 1. 2006-10-12. PMID:16846651. |
in the present study mice withdrawn from a 7-week oral nicotine treatment were administered morphine, following which their locomotor activities were recorded and the concentrations of dopamine, 5-hydroxytryptamine (5-ht), noradrenaline and their metabolites were measured in the caudate putamen (cpu) and nucleus accumbens (nac). |
2006-10-12 |
2023-08-12 |
mouse |
| Kazuhiro Ishikawa, Atsumi Nitta, Hiroyuki Mizoguchi, Akihiro Mohri, Rina Murai, Yoshiaki Miyamoto, Yukihiro Noda, Kiyoyuki Kitaichi, Kiyofumi Yamada, Toshitaka Nabeshim. Effects of single and repeated administration of methamphetamine or morphine on neuroglycan C gene expression in the rat brain. The international journal of neuropsychopharmacology. vol 9. issue 4. 2006-10-10. PMID:16146580. |
repeated map (chronic map) administration significantly increased ngc mrna levels in the frontal cortex, nucleus accumbens (nac), striatum, hippocampus, vta, and amygdala compared to acute map treatment. |
2006-10-10 |
2023-08-12 |
rat |
| Liliana Spina, Sandro Fenu, Rosanna Longoni, Emilia Rivas, Gaetano Di Chiar. Nicotine-conditioned single-trial place preference: selective role of nucleus accumbens shell dopamine D1 receptors in acquisition. Psychopharmacology. vol 184. issue 3-4. 2006-10-06. PMID:16341849. |
however, the role of da transmission of the two main subdivisions of the nucleus accumbens (nac), the shell and the core, in the motivational properties of nicotine is unknown. |
2006-10-06 |
2023-08-12 |
Not clear |
| Daniele Lecca, Fabio Cacciapaglia, Valentina Valentini, Janne Gronli, Saturnino Spiga, Gaetano Di Chiar. Preferential increase of extracellular dopamine in the rat nucleus accumbens shell as compared to that in the core during acquisition and maintenance of intravenous nicotine self-administration. Psychopharmacology. vol 184. issue 3-4. 2006-10-06. PMID:16397746. |
it has been reported that passive administration of nicotine increases preferentially extracellular dopamine (da) release in the shell as compared to that in the core of the nucleus accumbens (nac). |
2006-10-06 |
2023-08-12 |
rat |
| S Saellstroem Baum, Anke Huebner, M Krimphove, Rudolf Morgenstern, Abdulla A-B Badawy, Claudia D Spie. Nicotine stimulation on extracellular glutamate levels in the nucleus accumbens of ethanol-withdrawn rats in vivo. Alcoholism, clinical and experimental research. vol 30. issue 8. 2006-09-29. PMID:16899045. |
the effects and differences of nicotine stimulation on glutamate response measured by microdialysis in the nucleus accumbens (nac) between ethanol-withdrawn rats (ew group) and ethanol-naïve rats (control group) were investigated. |
2006-09-29 |
2023-08-12 |
rat |
| Markus Fendt, Isabel Schwienbacher, Hans-Ulrich Schnitzle. Carbachol injections into the nucleus accumbens induce 50 kHz calls in rats. Neuroscience letters. vol 401. issue 1-2. 2006-09-28. PMID:16563619. |
this is supported by studies demonstrating that infusions of the dopamine agonist amphetamine into the nucleus accumbens (nac), a key structure for appetitive behaviors, induce 50 khz calls. |
2006-09-28 |
2023-08-12 |
rat |
| Mark R Stefani, Bita Moghadda. Rule learning and reward contingency are associated with dissociable patterns of dopamine activation in the rat prefrontal cortex, nucleus accumbens, and dorsal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 34. 2006-09-28. PMID:16928870. |
we measured dopamine release in the prefrontal cortex (pfc), nucleus accumbens (nac), and dorsal striatum (ds) of rats exposed to the same maze apparatus under three behavioral conditions: a set-shift task in which reward depended on discrimination learning and extradimensional set-shifting, a yoked condition in which reward was intermittent and not under the control of the subject, and a "reward-retrieval" variant in which reward was certain on every trial. |
2006-09-28 |
2023-08-12 |
human |
| Peter Olausson, J David Jentsch, Natalie Tronson, Rachel L Neve, Eric J Nestler, Jane R Taylo. DeltaFosB in the nucleus accumbens regulates food-reinforced instrumental behavior and motivation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 36. 2006-09-26. PMID:16957076. |
repeated exposure to drugs of abuse or stress is known to persistently induce the transcription factor deltafosb in the nucleus accumbens (nac) and dorsal striatum, effects hypothesized to contribute to neuroadaptations in dopamine-regulated signaling. |
2006-09-26 |
2023-08-12 |
mouse |
| Yao-Ying Ma, Chang-Yong Guo, Peng Yu, David Yue-Wei Lee, Ji-Sheng Han, Cai-Lian Cu. The role of NR2B containing NMDA receptor in place preference conditioned with morphine and natural reinforcers in rats. Experimental neurology. vol 200. issue 2. 2006-09-21. PMID:16631172. |
experimental results showed that (1) an augmented expression of nr2b subunit was revealed by western blotting in the nucleus accumbens (nac) and the hippocampus in rats with cpp induced by morphine, but not by natural rewards such as food, novel environment and social interaction. |
2006-09-21 |
2023-08-12 |
rat |
| Ann C Voorhies, Ilene L Bernstei. Induction and expression of salt appetite: effects on Fos expression in nucleus accumbens. Behavioural brain research. vol 172. issue 1. 2006-09-20. PMID:16712968. |
the present studies examined expression of the immediate early gene fos in the nucleus accumbens (nac) as a marker of neuronal activation following the induction and expression of furosemide-induced sodium appetite. |
2006-09-20 |
2023-08-12 |
Not clear |
| José Antonio Fuentealba, Katia Gysling, Karin Magendzo, María Estela André. Repeated administration of the selective kappa-opioid receptor agonist U-69593 increases stimulated dopamine extracellular levels in the rat nucleus accumbens. Journal of neuroscience research. vol 84. issue 2. 2006-09-19. PMID:16676328. |
this effect is related to the inhibition of dopamine (da) release in the nucleus accumbens (nac) produced by the acute administration of kor agonists. |
2006-09-19 |
2023-08-12 |
rat |
| Jeremy J Day, Robert A Wheeler, Mitchell F Roitman, Regina M Carell. Nucleus accumbens neurons encode Pavlovian approach behaviors: evidence from an autoshaping paradigm. The European journal of neuroscience. vol 23. issue 5. 2006-09-18. PMID:16553795. |
here, we examined the activity of individual nucleus accumbens (nac) neurons during an autoshaping paradigm. |
2006-09-18 |
2023-08-12 |
rat |
| Heather C Brenhouse, Stefanie Montalto, James R Stella. Electrolytic lesions of a discrete area within the nucleus accumbens shell attenuate the long-term expression, but not early phase, of sensitization to cocaine. Behavioural brain research. vol 170. issue 2. 2006-09-14. PMID:16580740. |
the nucleus accumbens (nac), a major termination site of dopaminergic neurons, is believed to be involved in behavioral sensitization and studies have demonstrated that the nac shell can be split into five zones of analysis; the vertex, arch, cone, intermediate and ventrolateral zones [todtenkopf ms, stellar jr. assessment of tyrosine hydroxylase immunoreactive innervation in five subregions of the nucleus accumbens shell in rats treated with repeated cocaine. |
2006-09-14 |
2023-08-12 |
rat |
| Zheng-Xiong Xi, Jeremy G Gilbert, Xiao-Qing Peng, Arlene C Pak, Xia Li, Eliot L Gardne. Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 33. 2006-09-12. PMID:16914679. |
given the importance of dopamine, glutamate, and gaba in cocaine reward and relapse, we studied the effects of am251 [n-(piperidin-1-yl)-5-(4-iodophonyl)-1-(2,4-dichlorophenyl)-4-methyl-1h-pyrazole-3-carboxamide], a novel highly selective cb1 receptor antagonist, on cocaine-primed reinstatement of drug-seeking behavior and on cocaine-induced changes in extracellular da, glutamate, and gaba in the nucleus accumbens (nac) under reinstatement conditions. |
2006-09-12 |
2023-08-12 |
rat |