| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiuwu Zhang, Tong H Lee, Xueying Xiong, Qiang Chen, Colin Davidson, William C Wetsel, Everett H Ellinwoo. Methamphetamine induces long-term changes in GABAA receptor alpha2 subunit and GAD67 expression. Biochemical and biophysical research communications. vol 351. issue 1. 2006-12-22. PMID:17056007. |
western blot assay showed that meth sensitization decreases gaba(a) alpha2 subunit and gad(67) protein levels in the nucleus accumbens (nac) core and shell, and conversely, these proteins were increased in the caudate. |
2006-12-22 |
2023-08-12 |
rat |
| Donald C Cooper, William D Klipec, Melissa A Fowler, Emin D Ozka. A role for the subiculum in the brain motivation/reward circuitry. Behavioural brain research. vol 174. issue 2. 2006-12-20. PMID:16870273. |
the ventral subiculum (vsub) is an interface between the hippocampal formation and structures in the brain reward circuitry, such as the nucleus accumbens (nac) and prefrontal cortex (pfc). |
2006-12-20 |
2023-08-12 |
Not clear |
| Vladimir I Chefer, Agustin Zapata, Toni S Shippenberg, Peter M Bunga. Quantitative no-net-flux microdialysis permits detection of increases and decreases in dopamine uptake in mouse nucleus accumbens. Journal of neuroscience methods. vol 155. issue 2. 2006-12-18. PMID:16466808. |
here we report that the ed for da in the nucleus accumbens (nac) of the behaving mouse is increased following pharmacological inactivation of kappa-opioid receptors, a treatment previously shown to augment da uptake. |
2006-12-18 |
2023-08-12 |
mouse |
| Taku Nagai, Mina Ito, Noritaka Nakamichi, Hiroyuki Mizoguchi, Hiroyuki Kamei, Ayumi Fukakusa, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamad. The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 47. 2006-12-15. PMID:17122062. |
in vivo microdialysis revealed that microinjection of either tpa or plasmin into the nucleus accumbens (nac) significantly potentiated whereas plasminogen activator inhibitor-1 reduced the nicotine-induced dopamine release in the nac in a dose-dependent manner. |
2006-12-15 |
2023-08-12 |
mouse |
| Pamela B Yang, Alan C Swann, Nachum Dafn. Chronic methylphenidate modulates locomotor activity and sensory evoked responses in the VTA and NAc of freely behaving rats. Neuropharmacology. vol 51. issue 3. 2006-12-14. PMID:16824558. |
there is some evidence that psychostimulants, such as amphetamine and cocaine, activate the ventral tegmental area (vta) and nucleus accumbens (nac). |
2006-12-14 |
2023-08-12 |
rat |
| Ryan K Bachtell, Kimberly Whisler, David Karanian, David W Sel. Effects of intra-nucleus accumbens shell administration of dopamine agonists and antagonists on cocaine-taking and cocaine-seeking behaviors in the rat. Psychopharmacology. vol 183. issue 1. 2006-12-12. PMID:16163523. |
dopamine signaling in the nucleus accumbens (nac) plays an important role in regulating drug-taking and drug-seeking behaviors, but the role of d(1)- and d(2)-like receptors in this regulation remains unclear. |
2006-12-12 |
2023-08-12 |
rat |
| M E Walton, S W Kennerley, D M Bannerman, P E M Phillips, M F S Rushwort. Weighing up the benefits of work: behavioral and neural analyses of effort-related decision making. Neural networks : the official journal of the International Neural Network Society. vol 19. issue 8. 2006-12-12. PMID:16949252. |
we suggest that top-down signals from acc to nucleus accumbens (nac) and/or midbrain da cells may be vital for overcoming effort-related response costs. |
2006-12-12 |
2023-08-12 |
monkey |
| Arlene C Pak, Charles R Ashby, Christian A Heidbreder, Maria Pilla, Jeremy Gilbert, Zheng-Xiong Xi, Eliot L Gardne. The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions. The international journal of neuropsychopharmacology. vol 9. issue 5. 2006-12-11. PMID:16942635. |
increasing evidence suggests that enhanced dopamine (da) neurotransmission in the nucleus accumbens (nac) may play a role in mediating the reward and reinforcement produced by addictive drugs and in the attentional processing of drug-associated environmental cues. |
2006-12-11 |
2023-08-12 |
rat |
| K Ito, T Abekawa, T Koyam. Relationship between development of cross-sensitization to MK-801 and delayed increases in glutamate levels in the nucleus accumbens induced by a high dose of methamphetamine. Psychopharmacology. vol 187. issue 3. 2006-12-07. PMID:16850286. |
the present study hypothesized that delayed increases in extracellular glutamate (glu) levels in the nucleus accumbens (nac), induced by a high dose of methamphetamine (meth), can result in some functional changes of excitatory amino acid receptors, developing behavioral cross-sensitization to a non-competitive n-methyl-d-aspartate (nmda) receptor antagonist, mk-801. |
2006-12-07 |
2023-08-12 |
Not clear |
| Sachiyo Sakamoto, Shinichi Nakao, Munehiro Masuzawa, Takefumi Inada, Mervyn Maze, Nicholas P Franks, Koh Shing. The differential effects of nitrous oxide and xenon on extracellular dopamine levels in the rat nucleus accumbens: a microdialysis study. Anesthesia and analgesia. vol 103. issue 6. 2006-12-07. PMID:17122223. |
dopamine release in the nucleus accumbens (nac) plays a crucial role in the action of various psychotropic and addictive drugs, such as antagonists of the n-methyl-d-aspartate subtype of the glutamate. |
2006-12-07 |
2023-08-12 |
rat |
| Mariela F Perez, Francis J White, Xiu-Ti H. Dopamine D(2) receptor modulation of K(+) channel activity regulates excitability of nucleus accumbens neurons at different membrane potentials. Journal of neurophysiology. vol 96. issue 5. 2006-12-06. PMID:16885524. |
the nucleus accumbens (nac) is a forebrain area in the mesocorticolimbic dopamine (da) system that regulates many aspects of drug addiction. |
2006-12-06 |
2023-08-12 |
rat |
| Zhifang Dong, Huili Han, Meina Wang, Lin Xu, Wei Hao, Jun Ca. Morphine conditioned place preference depends on glucocorticoid receptors in both hippocampus and nucleus accumbens. Hippocampus. vol 16. issue 10. 2006-12-04. PMID:16897719. |
learned association between drugs of abuse and context is essential for the formation of drug conditioned place preference (cpp), which is believed to engage many brain regions including hippocampus and nucleus accumbens (nac). |
2006-12-04 |
2023-08-12 |
rat |
| Mina Ito, Taku Nagai, Hiroyuki Kamei, Noritaka Nakamichi, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamad. Involvement of tissue plasminogen activator-plasmin system in depolarization-evoked dopamine release in the nucleus accumbens of mice. Molecular pharmacology. vol 70. issue 5. 2006-12-04. PMID:16908600. |
in the present study, we investigated the role of the tpa-plasmin system in depolarization-evoked dopamine (da) and acetylcholine (ach) release in the nucleus accumbens (nac) and hippocampus, respectively, of mice, by using in vivo microdialysis. |
2006-12-04 |
2023-08-12 |
mouse |
| Nu-Chu Liang, Andras Hajnal, Ralph Norgre. Sham feeding corn oil increases accumbens dopamine in the rat. American journal of physiology. Regulatory, integrative and comparative physiology. vol 291. issue 5. 2006-11-29. PMID:16763080. |
both real and sham feeding of sucrose increase dopamine (da) overflow in the nucleus accumbens (nac). |
2006-11-29 |
2023-08-12 |
rat |
| K Ito, T Abekawa, T Koyam. Valproate blocks high-dose methamphetamine-induced behavioral cross-sensitization to locomotion-inducing effect of dizocilpine (MK-801), but not methamphetamine. Psychopharmacology. vol 186. issue 4. 2006-11-28. PMID:16758239. |
our group has recently shown that methamphetamine (meth) (2.5 mg/kg) induced delayed increases in glutamate (glu) levels in the rat nucleus accumbens (nac), and that its repeated administration leads to behavioral cross-sensitization to a selective uncompetitive n-methyl-d-aspartate (nmda) receptor antagonist, dizocilpine (mk-801). |
2006-11-28 |
2023-08-12 |
rat |
| Mark S Todtenkopf, Aram Parsegian, Alipi Naydenov, Rachael L Neve, Christine Konradi, William A Carlezo. Brain reward regulated by AMPA receptor subunits in nucleus accumbens shell. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 45. 2006-11-28. PMID:17093088. |
drugs of abuse alter expression of ampa-type glutamate receptor subunits (glurs) in the nucleus accumbens (nac), a key component of brain reward systems. |
2006-11-28 |
2023-08-12 |
rat |
| Elena Butovsky, Ana Juknat, Judith Elbaz, Maytal Shabat-Simon, Raya Eilam, Abraham Zangen, Miriam Altstein, Zvi Voge. Chronic exposure to Delta9-tetrahydrocannabinol downregulates oxytocin and oxytocin-associated neurophysin in specific brain areas. Molecular and cellular neurosciences. vol 31. issue 4. 2006-11-22. PMID:16513365. |
; 7 days) to rats, downregulates the expression of oxytocin-neurophysin (ot-np) mrna and of ot and oxytocin-associated np (npot) immunoreactivity in nucleus accumbens (nac) and ventral tegmental area (vta), brain areas involved in reward and addiction. |
2006-11-22 |
2023-08-12 |
rat |
| Helen H J Pothuizen, Joram Feldon, Benjamin K Ye. Facilitated extinction of appetitive instrumental conditioning following excitotoxic lesions of the core or the medial shell subregion of the nucleus accumbens in rats. Experimental brain research. vol 172. issue 1. 2006-11-14. PMID:16432699. |
here, we evaluated the effect of n-methyl-d: -aspartate (nmda)-induced excitotoxic lesions restricted to either the core or the medial shell subregions of the nucleus accumbens (nac) on extinction in rats using a trial discrete fixed ratio-5 (fr-5) appetitive operant procedure. |
2006-11-14 |
2023-08-12 |
rat |
| Xun Wan, Laura L People. Firing patterns of accumbal neurons during a pavlovian-conditioned approach task. Journal of neurophysiology. vol 96. issue 2. 2006-11-08. PMID:16641388. |
the nucleus accumbens (nac) is necessary for the expression of pavlovian-conditioned approach behavior but not for the expression of instrumental behavior conditioned in sessions that set a low response requirement. |
2006-11-08 |
2023-08-12 |
rat |
| Stephanie Fulton, Pavlos Pissios, Ramon Pinol Manchon, Linsey Stiles, Lauren Frank, Emmanuel N Pothos, Eleftheria Maratos-Flier, Jeffrey S Flie. Leptin regulation of the mesoaccumbens dopamine pathway. Neuron. vol 51. issue 6. 2006-11-07. PMID:16982425. |
retrograde tracing combined with pstat3 immunohistochemistry show leptin-responsive vta neurons projecting to nucleus accumbens (nac). |
2006-11-07 |
2023-08-12 |
mouse |