| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sade Spencer, Edgardo Falcon, Jaswinder Kumar, Vaishnav Krishnan, Shibani Mukherjee, Shari G Birnbaum, Colleen A McClun. Circadian genes Period 1 and Period 2 in the nucleus accumbens regulate anxiety-related behavior. The European journal of neuroscience. vol 37. issue 2. 2013-06-27. PMID:23039899. |
moreover, we found that mper1 and mper2 expression was reduced in the nucleus accumbens (nac) after exposure to chronic social defeat stress, a paradigm that led to increased anxiety-related behavior. |
2013-06-27 |
2023-08-12 |
mouse |
| Roland Bock, J Hoon Shin, Alanna R Kaplan, Alice Dobi, Eric Markey, Paul F Kramer, Christina M Gremel, Christine H Christensen, Martin F Adrover, Veronica A Alvare. Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use. Nature neuroscience. vol 16. issue 5. 2013-06-27. PMID:23542690. |
we found that individual variability in the development of highly motivated and perseverative behavior toward cocaine is associated with synaptic plasticity in medium spiny neurons expressing dopamine d2 receptors (d2-msns) in the nucleus accumbens (nac) of mice. |
2013-06-27 |
2023-08-12 |
mouse |
| Michael Lazarus, Zhi-Li Huang, Jun Lu, Yoshihiro Urade, Jiang-Fan Che. How do the basal ganglia regulate sleep-wake behavior? Trends in neurosciences. vol 35. issue 12. 2013-06-26. PMID:22858523. |
furthermore, we propose a model whereby adenosine and dopamine receptors in the nucleus accumbens (nac) are involved in the integration of behavioral processes and the induction of wakefulness through cortical activation. |
2013-06-26 |
2023-08-12 |
Not clear |
| Candace R Lewis, Kelsey Staudinger, Lena Scheck, M Foster Oliv. The Effects of Maternal Separation on Adult Methamphetamine Self-Administration, Extinction, Reinstatement, and MeCP2 Immunoreactivity in the Nucleus Accumbens. Frontiers in psychiatry. vol 4. 2013-06-21. PMID:23785337. |
given the known influence of early life stress and drug exposure on epigenetic processes, we also investigated group differences in levels of the epigenetic marker methyl cpg binding protein 2 (mecp2) in the nucleus accumbens (nac) core. |
2013-06-21 |
2023-08-12 |
rat |
| Mia Ericson, Peipei Chau, Louise Adermark, Bo Söderpal. Rising taurine and ethanol concentrations in nucleus accumbens interact to produce the dopamine-activating effects of alcohol. Advances in experimental medicine and biology. vol 775. 2013-06-12. PMID:23392937. |
ethanol is known to increase extracellular levels of both dopamine and taurine in the nucleus accumbens (nac), a part of the brain reward system, but the two events have not been connected. |
2013-06-12 |
2023-08-12 |
human |
| Shashank Tandon, Sidney A Simon, Miguel A L Nicoleli. Appetitive changes during salt deprivation are paralleled by widespread neuronal adaptations in nucleus accumbens, lateral hypothalamus, and central amygdala. Journal of neurophysiology. vol 108. issue 4. 2013-06-11. PMID:22572944. |
because forebrain areas such as the lateral hypothalamus (lh), central amygdala (cea), and nucleus accumbens (nac) are known to play an important role in this behavior, we recorded from these areas while water-deprived (wd) and salt-deprived (sd) rats performed a two-bottle choice test between 0.5 m salt (nacl) and 0.4 m sucrose. |
2013-06-11 |
2023-08-12 |
rat |
| Franciela P Della, Helena M Abelaira, Gislaine Z Réus, Altamir R Antunes, Maria Augusta B Dos Santos, Giovanni Zappelinni, Amanda V Steckert, Francieli Vuolo, Letícia S Galant, Felipe Dal-Pizzol, Flávio Kapczinski, João Queved. Tianeptine exerts neuroprotective effects in the brain tissue of rats exposed to the chronic stress model. Pharmacology, biochemistry, and behavior. vol 103. issue 2. 2013-06-11. PMID:23036485. |
additionally, il-6, il-1, tnf-α levels and oxidative stress parameters were assessed in the prefrontal cortex (pfc), hippocampus (hpc), amygdala (amy) and nucleus accumbens (nac) in all of the experimental groups studied. |
2013-06-11 |
2023-08-12 |
rat |
| Yonwoo Jung, Patrick J Mulholland, Shari L Wiseman, L Judson Chandler, Marina R Picciott. Constitutive knockout of the membrane cytoskeleton protein beta adducin decreases mushroom spine density in the nucleus accumbens but does not prevent spine remodeling in response to cocaine. The European journal of neuroscience. vol 37. issue 1. 2013-06-11. PMID:23106536. |
using diolistic labeling with the lipophilic dye dii, we found that the density of mature mushroom-shaped spines was significantly decreased in the nucleus accumbens (nac) in brain slices from βadd-knockout (ko) mice as compared to their wildtype (wt) siblings. |
2013-06-11 |
2023-08-12 |
mouse |
| Ramesh Chandra, Jeffrey D Lenz, Amy M Gancarz, Dipesh Chaudhury, Gabrielle L Schroeder, Ming-Hu Han, Joseph F Cheer, David M Dietz, Mary Kay Lob. Optogenetic inhibition of D1R containing nucleus accumbens neurons alters cocaine-mediated regulation of Tiam1. Frontiers in molecular neuroscience. vol 6. 2013-06-10. PMID:23745104. |
these d1-msns in the nucleus accumbens (nac) positively regulate drug seeking, reward, and locomotor behavioral effects as well as the morphological adaptations of psychostimulant drugs. |
2013-06-10 |
2023-08-12 |
rat |
| Guiqin Xie, Krešimir Krnjević, Jiang-Hong Y. Salsolinol modulation of dopamine neurons. Frontiers in behavioral neuroscience. vol 7. 2013-06-10. PMID:23745110. |
previous evidence obtained in vivo links salsolinol with the mesolimbic dopaminergic (da) system: salsolinol is self-administered into the posterior of the ventral tegmental area (pvta) of rats; intra-vta administration of salsolinol induces a strong conditional place preference and increases dopamine release in the nucleus accumbens (nac). |
2013-06-10 |
2023-08-12 |
human |
| Ya Xu, Xiu-Fang Lv, Cai-Lian Cui, Fei-Fei Ge, Yi-Jing Li, Hao-Lin Zhan. Essential role of NR2B-containing NMDA receptor-ERK pathway in nucleus accumbens shell in morphine-associated contextual memory. Brain research bulletin. vol 89. issue 1-2. 2013-06-06. PMID:22776695. |
although it has been shown that extracellular signal-regulated kinase 1/2 (erk1/2) activity in the nucleus accumbens (nac) is modulated by the primary rewarding effect of opiates, little is known as to its role in the morphine-associated contextual memory. |
2013-06-06 |
2023-08-12 |
rat |
| Michael P Saddoris, Jonathan A Sugam, Fabio Cacciapaglia, Regina M Carell. Rapid dopamine dynamics in the accumbens core and shell: learning and action. Frontiers in bioscience (Elite edition). vol 5. 2013-06-05. PMID:23276989. |
emerging data has suggested that this same principle of separate neural circuits may be applicable within structural subregions, such as the core and shell of the nucleus accumbens (nac). |
2013-06-05 |
2023-08-12 |
Not clear |
| Panayotis K Thanos, Lisa Robison, Eric J Nestler, Ronald Kim, Michael Michaelides, Mary-Kay Lobo, Nora D Volko. Mapping brain metabolic connectivity in awake rats with μPET and optogenetic stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 15. 2013-06-05. PMID:23575833. |
positron emission tomography (pet) with [(18)f]2-fluoro-2-deoxy-d-glucose was used to measure changes in regional brain glucose metabolism (bglum) in response to optogenetic stimulation (using the excitatory channelrhodopsin-2) of the nucleus accumbens (nac) in awake rats. |
2013-06-05 |
2023-08-12 |
rat |
| Jose M Lerma-Cabrera, Francisca Carvajal, Gabriela Chotro, Mirari Gaztañaga, Montserrat Navarro, Todd E Thiele, Inmaculada Cuber. MC4-R signaling within the nucleus accumbens shell, but not the lateral hypothalamus, modulates ethanol palatability in rats. Behavioural brain research. vol 239. 2013-06-04. PMID:23146409. |
recently, we have shown that nucleus accumbens (nac), but not lateral hypothalamic (lh), infusion of a selective mc4-r agonist decreases ethanol consumption. |
2013-06-04 |
2023-08-12 |
rat |
| Ulf J Müller, Jürgen Voges, Johann Steiner, Imke Galazky, Hans-Jochen Heinze, Michaela Möller, Jared Pisapia, Casey Halpern, Arthur Caplan, Bernhard Bogerts, Jens Kuh. Deep brain stimulation of the nucleus accumbens for the treatment of addiction. Annals of the New York Academy of Sciences. vol 1282. 2013-06-03. PMID:23227826. |
in this review, beginning with an introduction of deep brain stimulation (dbs), we highlight the importance of the nucleus accumbens (nac) in the context of the reward circuitry and addictive behavior. |
2013-06-03 |
2023-08-12 |
Not clear |
| Xiao-Jie Wu, Jing Zhang, Chun-Ling Wei, Zhi-Qiang Liu, Wei Re. [Repeated morphine pretreatment reduces glutamatergic synaptic potentiation in the nucleus accumbens induced by acute morphine exposure]. Sheng li xue bao : [Acta physiologica Sinica]. vol 64. issue 2. 2013-05-30. PMID:22513467. |
the glutamatergic projection from prefrontal cortex (pfc) to the nucleus accumbens (nac) plays an important role in rewarding effects. |
2013-05-30 |
2023-08-12 |
rat |
| Xiaobo Wu, Meimei Shi, Hengli Ling, Chunling Wei, Yihui Liu, Zhiqiang Liu, Wei Re. Effects of morphine withdrawal on the membrane properties of medium spiny neurons in the nucleus accumbens shell. Brain research bulletin. vol 90. 2013-05-30. PMID:23069789. |
medium spiny neurons (msns) in the nucleus accumbens (nac) undergo persistent alterations in their biological and physiological characteristics upon exposure to drugs of abuse. |
2013-05-30 |
2023-08-12 |
rat |
| Jun Zhu, Michael T Bardo, Linda P Dwoski. Distinct effects of enriched environment on dopamine clearance in nucleus accumbens shell and core following systemic nicotine administration. Synapse (New York, N.Y.). vol 67. issue 2. 2013-05-29. PMID:23065942. |
nucleus accumbens (nac) shell and core respond differentially to regulate the rewarding properties and locomotor stimulant effects of psychostimulants. |
2013-05-29 |
2023-08-12 |
rat |
| Nan Li, Li Gao, Xue-lian Wang, Lei Chen, Wei Fang, Shun-nan Ge, Guo-dong Ga. Deep brain stimulation of the bilateral nucleus accumbens in normal rhesus monkey. Neuroreport. vol 24. issue 1. 2013-05-23. PMID:23196414. |
the nucleus accumbens (nac) has been considered as a novel target of deep brain stimulation (dbs) for intractable psychiatric disorders. |
2013-05-23 |
2023-08-12 |
monkey |
| Jianjun Sun, Jinbin Xu, Nigel J Cairns, Joel S Perlmutter, Robert H Mac. Dopamine D1, D2, D3 receptors, vesicular monoamine transporter type-2 (VMAT2) and dopamine transporter (DAT) densities in aged human brain. PloS one. vol 7. issue 11. 2013-05-22. PMID:23185343. |
dopamine d(1), d(2), and d(3) receptors are extensively distributed throughout striatum; the highest density of d(3) receptors occurred in the nucleus accumbens (nac). |
2013-05-22 |
2023-08-12 |
human |