| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexia Polissidis, Andreas Galanopoulos, George Naxakis, Demetris Papahatjis, Zeta Papadopoulou-Daifoti, Katerina Antonio. The cannabinoid CB1 receptor biphasically modulates motor activity and regulates dopamine and glutamate release region dependently. The international journal of neuropsychopharmacology. vol 16. issue 2. 2013-08-21. PMID:22391102. |
the present study examines the effects of high and low dose win55,212-2, a cb1 receptor agonist, on extracellular dopamine and glutamate release in vivo via brain microdialysis in the nucleus accumbens (nac), striatum and prefrontal cortex (pfc) in parallel to its effects on locomotor activity. |
2013-08-21 |
2023-08-12 |
Not clear |
| Carine Chassain, Guy Bielicki, Carole Carcenac, Anne-Claire Ronsin, Jean-Pierre Renou, Marc Savasta, Franck Duri. Does MPTP intoxication in mice induce metabolite changes in the nucleus accumbens? A ¹H nuclear MRS study. NMR in biomedicine. vol 26. issue 3. 2013-08-20. PMID:23059905. |
the aim of this study was to determine whether the changes previously observed in the motor part of the striatum were reproduced in a ventral part of the striatum, the nucleus accumbens (nac). |
2013-08-20 |
2023-08-12 |
mouse |
| V Warnault, E Darcq, A Levine, S Barak, D Ro. Chromatin remodeling--a novel strategy to control excessive alcohol drinking. Translational psychiatry. vol 3. 2013-08-15. PMID:23423140. |
in line with these behavioral findings, we demonstrate that excessive alcohol drinking increases dnmt1 levels and reduces histone h4 acetylation in the nucleus accumbens (nac) of rodents. |
2013-08-15 |
2023-08-12 |
mouse |
| Emily J Knight, Hoon-Ki Min, Sun-Chul Hwang, Michael P Marsh, Seungleal Paek, Inyong Kim, Joel P Felmlee, Osama A Abulseoud, Kevin E Bennet, Mark A Frye, Kendall H Le. Nucleus accumbens deep brain stimulation results in insula and prefrontal activation: a large animal FMRI study. PloS one. vol 8. issue 2. 2013-08-13. PMID:23441210. |
deep brain stimulation (dbs) of the nucleus accumbens (nac) has previously been investigated clinically for the treatment of several psychiatric conditions, including obsessive-compulsive disorder and treatment resistant depression. |
2013-08-13 |
2023-08-12 |
Not clear |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Kuei-Sen Hs. A single in vivo cocaine administration impairs 5-HT(1B) receptor-induced long-term depression in the nucleus accumbens. Journal of neurochemistry. vol 125. issue 6. 2013-08-06. PMID:23452061. |
the nucleus accumbens (nac) is a crucial forebrain nucleus implicated in reward-based decision-making. |
2013-08-06 |
2023-08-12 |
mouse |
| Alexis W Ary, Kevin D Lominac, Melissa G Wroten, Amy R Williams, Rianne R Campbell, Osnat Ben-Shahar, Georg von Jonquieres, Matthias Klugmann, Karen K Szumlinsk. Imbalances in prefrontal cortex CC-Homer1 versus CC-Homer2 expression promote cocaine preference. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 19. 2013-08-06. PMID:23658151. |
intriguingly, both these transgenic manipulations produced glutamate anomalies within the nucleus accumbens (nac) of cocaine-naive animals that are reminiscent of those observed in cocaine experienced animals, including reduced basal extracellular glutamate content, reduced homer1/2 and glutamate receptor expression, and augmented cocaine-elicited glutamate release. |
2013-08-06 |
2023-08-12 |
mouse |
| Venkata Siva Sai Sujith Sajja, Matthew Galloway, Farhad Ghoddoussi, Andrea Kepsel, Pamela VandeVor. Effects of blast-induced neurotrauma on the nucleus accumbens. Journal of neuroscience research. vol 91. issue 4. 2013-08-05. PMID:23335267. |
the nucleus accumbens (nac) plays an important role in reward, addiction, aggression, and fear pathways. |
2013-08-05 |
2023-08-12 |
Not clear |
| E Lizárraga-Mollinedo, C Alvarez, E Fernández-Millán, F Escrivá, C González-Martín, E Salas, J M Pérez-Ortiz, L F Alguaci. Undernutrition upregulates fumarate hydratase in the rat nucleus accumbens. Metabolic brain disease. vol 28. issue 1. 2013-08-02. PMID:23160834. |
this work has been focused to investigate fh activity in the nucleus accumbens (nac) of undernourished rats, taking into account that malnutrition has been related to increased responsiveness to food and drug reward. |
2013-08-02 |
2023-08-12 |
rat |
| Bryan B Gore, Larry S Zweife. Genetic reconstruction of dopamine D1 receptor signaling in the nucleus accumbens facilitates natural and drug reward responses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 20. 2013-08-02. PMID:23678109. |
using conditional reconstruction of functional d1r signaling in d1r knock-out mice, we define distinct requirements of d1r in subregions of the nucleus accumbens (nac) for specific dimensions of reward. |
2013-08-02 |
2023-08-12 |
mouse |
| Kathryn D Fischer, Alexander C W Houston, George V Rebe. Role of the major glutamate transporter GLT1 in nucleus accumbens core versus shell in cue-induced cocaine-seeking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 22. 2013-07-26. PMID:23719800. |
relapse to cocaine-seeking behavior requires an increase in nucleus accumbens (nac) core glutamate transmission. |
2013-07-26 |
2023-08-12 |
rat |
| Maria Stratinaki, Artemis Varidaki, Vasiliki Mitsi, Subroto Ghose, Jane Magida, Caroline Dias, Scott J Russo, Vincent Vialou, Barbara J Caldarone, Carol A Tamminga, Eric J Nestler, Venetia Zachario. Regulator of G protein signaling 4 [corrected] is a crucial modulator of antidepressant drug action in depression and neuropathic pain models. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 20. 2013-07-25. PMID:23630294. |
we first analyzed human postmortem brain tissue and found robust up-regulation of rgs4 expression in the nucleus accumbens (nac) of subjects receiving standard antidepressant medications that target monoamine systems. |
2013-07-25 |
2023-08-12 |
mouse |
| Shunnan Ge, Chongwang Chang, John R Adler, Haikang Zhao, Xiaozan Chang, Li Gao, Heming Wu, Jing Wang, Nan Li, Xuelian Wang, Guodong Ga. Long-term changes in the personality and psychopathological profile of opiate addicts after nucleus accumbens ablative surgery are associated with treatment outcome. Stereotactic and functional neurosurgery. vol 91. issue 1. 2013-07-23. PMID:23154203. |
to investigate the long-term outcome and changes of the personality and psychopathological profile of opiate addicts after bilateral stereotactic nucleus accumbens (nac) ablative surgery. |
2013-07-23 |
2023-08-12 |
Not clear |
| John W Muschamp, William A Carlezo. Roles of nucleus accumbens CREB and dynorphin in dysregulation of motivation. Cold Spring Harbor perspectives in medicine. vol 3. issue 2. 2013-07-18. PMID:23293139. |
psychostimulants such as amphetamine and cocaine are believed to produce dependence by causing rapid, supraphysiological elevations in synaptic dopamine (da) within the nucleus accumbens (nac) (volkow et al. |
2013-07-18 |
2023-08-12 |
Not clear |
| Cristine L Czachowski, Michael J Delory, Jason D Pop. Behavioral and neurotransmitter specific roles for the ventral tegmental area in reinforcer-seeking and intake. Alcoholism, clinical and experimental research. vol 36. issue 10. 2013-07-12. PMID:22432593. |
the primary dopamine projections within this system originate in the vta and innervate several areas including the nucleus accumbens (nac) and prefrontal cortex (pfc), and the pfc has afferent glutamate projections to the vta and the nac. |
2013-07-12 |
2023-08-12 |
Not clear |
| Jocelyn M Richard, Kent C Berridg. Prefrontal cortex modulates desire and dread generated by nucleus accumbens glutamate disruption. Biological psychiatry. vol 73. issue 4. 2013-07-12. PMID:22981656. |
corticolimbic circuits, including direct projections from prefrontal cortex to nucleus accumbens (nac), permit top-down control of intense motivations generated by subcortical circuits. |
2013-07-12 |
2023-08-12 |
rat |
| Haichen Niu, Yingwei Zheng, Tanzeel Huma, Joshua D Rizak, Ling Li, Guimei Wang, He Ren, Liqi Xu, Jianzhen Yang, Yuanye Ma, Hao Le. Lesion of olfactory epithelium attenuates expression of morphine-induced behavioral sensitization and reinstatement of drug-primed conditioned place preference in mice. Pharmacology, biochemistry, and behavior. vol 103. issue 3. 2013-07-09. PMID:23103203. |
compared to the saline-treated ones, the zne-treated animals showed reduced c-fos expression in the nucleus accumbens (nac) associated with behavioral sensitization, and in the nac, cingulate cortex, dentate gyrus, amygdala, lateral hypothalamus and ventral tegmental area associated with cpp reinstatement. |
2013-07-09 |
2023-08-12 |
mouse |
| Ilona Obara, Scott P Goulding, Adam T Gould, Kevin D Lominac, Jia-Hua Hu, Ping Wu Zhang, Georg von Jonquieres, Marlin Dehoff, Bo Xiao, Peter H Seeburg, Paul F Worley, Matthias Klugmann, Karen K Szumlinsk. Homers at the Interface between Reward and Pain. Frontiers in psychiatry. vol 4. 2013-07-04. PMID:23761764. |
however, heroin cpp did not depend upon full homer1c expression within the nucleus accumbens (nac), as cpp occurred in controls infused locally with small hairpin rna-homer1c, although intra-nac and/or intrathecal cdna-homer1c, -homer1a, and -homer2b infusions (to best mimic cci's effects) were sufficient to blunt heroin cpp in uninjured mice. |
2013-07-04 |
2023-08-12 |
mouse |
| J E Eipper-Mains, D D Kiraly, M O Duff, M J Horowitz, C J McManus, B A Eipper, B R Graveley, R E Main. Effects of cocaine and withdrawal on the mouse nucleus accumbens transcriptome. Genes, brain, and behavior. vol 12. issue 1. 2013-07-03. PMID:23094851. |
the gabaergic medium spiny neurons of the nucleus accumbens (nac) exhibit changes in the expression of genes encoding receptors for glutamate and in the signaling pathways triggered by dopamine binding to g-protein-coupled dopamine receptors. |
2013-07-03 |
2023-08-12 |
mouse |
| Xia Li, Zheng-Xiong Xi, Athina Marko. Metabotropic glutamate 7 (mGlu7) receptor: a target for medication development for the treatment of cocaine dependence. Neuropharmacology. vol 66. 2013-07-02. PMID:22546614. |
systemic or local administration of amn082 into the nucleus accumbens (nac), a critical brain region involved in reward and drug dependence processes, inhibited the reinforcing and motivational effects of cocaine, heroin and ethanol, as assessed by the intravenous drug self-administration procedure. |
2013-07-02 |
2023-08-12 |
Not clear |
| E Salas, E Alonso, M J Polanco, M V Cano, M Ruiz-Gayo, L F Alguaci. Differential regulation of CDK5 and c-Fos expression by morphine in the brain of Lewis and Fischer 344 rat strains. Neuroscience. vol 230. 2013-07-01. PMID:23153991. |
the number of cdk5 immunoreactive cells was significantly higher in the nucleus accumbens (nac), the locus coeruleus (lc) and the nucleus tractus solitarius (nts) of saline-injected f344 rats than in those of the lewis rats. |
2013-07-01 |
2023-08-12 |
rat |