| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Wallström, M Khademi, M Andersson, R Weissert, C Linington, T Olsso. Increased reactivity to myelin oligodendrocyte glycoprotein peptides and epitope mapping in HLA DR2(15)+ multiple sclerosis. European journal of immunology. vol 28. issue 10. 1998-12-15. PMID:9808202. |
myelin oligodendrocyte glycoprotein (mog) is a surface-exposed minor myelin component that is a prime candidate autoantigen. |
1998-12-15 |
2023-08-12 |
Not clear |
| P Hjelmström, A E Juedes, J Fjell, N H Ruddl. B-cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitization. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 9. 1998-11-18. PMID:9794370. |
myelin oligodendrocyte glycoprotein (mog) induced experimental allergic encephalomyelitis (eae) is an animal model for the central nervous system disease multiple sclerosis (ms). |
1998-11-18 |
2023-08-12 |
mouse |
| N K de Rosbo, A Ben-Nu. T-cell responses to myelin antigens in multiple sclerosis; relevance of the predominant autoimmune reactivity to myelin oligodendrocyte glycoprotein. Journal of autoimmunity. vol 11. issue 4. 1998-11-05. PMID:9776706. |
more relevant to ms pathogenesis may be, as we outlined in this review, the autoimmune reactivity directed against minor myelin proteins, in particular the cns-specific myelin oligodendrocyte glycoprotein (mog). |
1998-11-05 |
2023-08-12 |
Not clear |
| E B Samoilova, J L Horton, Y Che. Acceleration of experimental autoimmune encephalomyelitis in interleukin-10-deficient mice: roles of interleukin-10 in disease progression and recovery. Cellular immunology. vol 188. issue 2. 1998-10-29. PMID:9756642. |
we found that il-10- but not il-4-deficient mice had accelerated eae following immunization with myelin oligodendrocyte glycoprotein (mog). |
1998-10-29 |
2023-08-12 |
mouse |
| Y Okuda, S Sakoda, C C Bernard, T Yanagihar. The development of autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein is associated with an upregulation of both proinflammatory and immunoregulatory cytokines in the central nervous system. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 18. issue 6. 1998-10-16. PMID:9660249. |
we report here that gene expression for both proinflammatory and immunoregulatory cytokines increased during the course of disease in the cns of mice with myelin oligodendrocyte glycoprotein (mog)-induced nonrelapsing eae. |
1998-10-16 |
2023-08-12 |
mouse |
| P Hjelmström, J E Penzotti, R M Henne, T P Lybran. A molecular model of myelin oligodendrocyte glycoprotein. Journal of neurochemistry. vol 71. issue 4. 1998-10-14. PMID:9751210. |
myelin oligodendrocyte glycoprotein (mog) is a protein on the surface of myelin sheaths. |
1998-10-14 |
2023-08-12 |
mouse |
| Y Okuda, C C Bernard, H Fujimura, T Yanagihara, S Sakod. Fas has a crucial role in the progression of experimental autoimmune encephalomyelitis. Molecular immunology. vol 35. issue 5. 1998-09-30. PMID:9747891. |
the frequency of myelin oligodendrocyte glycoprotein (mog)-induced eae in b6.lpr mice was significantly lower than that in b6 mice (19% vs 94%). |
1998-09-30 |
2023-08-12 |
mouse |
| Y Okuda, S Sakoda, C C Bernard, H Fujimura, Y Saeki, T Kishimoto, T Yanagihar. IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein. International immunology. vol 10. issue 5. 1998-09-08. PMID:9645618. |
the role of il-6 in experimental autoimmune encephalomyelitis (eae) provoked by myelin oligodendrocyte glycoprotein (mog) was investigated using il-6-deficient mice. |
1998-09-08 |
2023-08-12 |
mouse |
| T Litzenburger, R Fässler, J Bauer, H Lassmann, C Linington, H Wekerle, A Iglesia. B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice. The Journal of experimental medicine. vol 188. issue 1. 1998-08-14. PMID:9653093. |
we studied the cellular basis of self tolerance of b cells specific for brain autoantigens using transgenic mice engineered to produce high titers of autoantibodies against the myelin oligodendrocyte glycoprotein (mog), a surface component of central nervous system myelin. |
1998-08-14 |
2023-08-12 |
mouse |
| H P Eugster, K Frei, M Kopf, H Lassmann, A Fontan. IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. European journal of immunology. vol 28. issue 7. 1998-08-13. PMID:9692887. |
experimental autoimmune encephalomyelitis (eae) is induced by immunization with myelin components including myelin oligodendrocyte glycoprotein (mog). |
1998-08-13 |
2023-08-12 |
mouse |
| I Dahlman, J C Lorentzen, K L de Graaf, A Stefferl, C Linington, H Luthman, T Olsso. Quantitative trait loci disposing for both experimental arthritis and encephalomyelitis in the DA rat; impact on severity of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis and antibody isotype pattern. European journal of immunology. vol 28. issue 7. 1998-08-13. PMID:9692888. |
we have investigated whether five non-mhc qtl controlling susceptibility to experimental arthritis in the da rat also influence myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) in an f2 intercross between inbred da and pvg.rt1a rats. |
1998-08-13 |
2023-08-12 |
rat |
| I Mews, M Bergmann, S Bunkowski, F Gullotta, W Brüc. Oligodendrocyte and axon pathology in clinically silent multiple sclerosis lesions. Multiple sclerosis (Houndmills, Basingstoke, England). vol 4. issue 2. 1998-07-10. PMID:9599334. |
oligodendrocytes were identified by immunocytochemistry for myelin oligodendrocyte glycoprotein (mog) and in situ hybridization for proteolipid protein (plp) mrna. |
1998-07-10 |
2023-08-12 |
Not clear |
| E A Leadbetter, C R Bourque, B Devaux, C D Olson, G H Sunshine, S Hirani, B P Wallner, D E Smilek, M P Hap. Experimental autoimmune encephalomyelitis induced with a combination of myelin basic protein and myelin oligodendrocyte glycoprotein is ameliorated by administration of a single myelin basic protein peptide. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 1. 1998-07-09. PMID:9647262. |
multiple sclerosis is an autoimmune disease of the central nervous system in which t cell reactivity to several myelin proteins, including myelin basic protein (mbp), proteolipid protein, and myelin oligodendrocyte glycoprotein (mog), has been implicated in the perpetuation of the disease state. |
1998-07-09 |
2023-08-12 |
mouse |
| C Ewing, C C Bernar. Insights into the aetiology and pathogenesis of multiple sclerosis. Immunology and cell biology. vol 76. issue 1. 1998-05-21. PMID:9553776. |
the primary target autoantigen in ms has yet to be definitively identified, but as well as the major myelin proteins, it is now clear that minor myelin components, such as myelin oligodendrocyte glycoprotein (mog) may play a primary role in disease initiation. |
1998-05-21 |
2023-08-12 |
Not clear |
| U C Sahrbacher, F Lechner, H P Eugster, K Frei, H Lassmann, A Fontan. Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis. European journal of immunology. vol 28. issue 4. 1998-05-13. PMID:9565373. |
in this study mice genetically deficient for inos are shown to be susceptible to eae induced by immunization with myelin oligodendrocyte glycoprotein (mog). |
1998-05-13 |
2023-08-12 |
mouse |
| J Bettadapura, K K Menon, S Moritz, J Liu, C C Bernar. Expression, purification, and encephalitogenicity of recombinant human myelin oligodendrocyte glycoprotein. Journal of neurochemistry. vol 70. issue 4. 1998-04-23. PMID:9523576. |
myelin oligodendrocyte glycoprotein (mog), a putative autoantigen in multiple sclerosis (ms), is a quantitatively minor component of the cns. |
1998-04-23 |
2023-08-12 |
mouse |
| A Tourbah, C Linnington, C Bachelin, V Avellana-Adalid, H Wekerle, A Baron-Van Evercoore. Inflammation promotes survival and migration of the CG4 oligodendrocyte progenitors transplanted in the spinal cord of both inflammatory and demyelinated EAE rats. Journal of neuroscience research. vol 50. issue 5. 1998-02-18. PMID:9418972. |
eae was induced by immunization with the encephalitogenic peptide of myelin basic protein (amino acids 68-88; c1) in adjuvant, either alone or in combination with a single injection of an anti-myelin oligodendrocyte glycoprotein (mog) antibody to enhance central nervous system (cns) demyelination. |
1998-02-18 |
2023-08-12 |
rat |
| J Liu, M W Marino, G Wong, D Grail, A Dunn, J Bettadapura, A J Slavin, L Old, C C Bernar. TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination. Nature medicine. vol 4. issue 1. 1998-01-23. PMID:9427610. |
to determine the contribution of tnf to the pathogenesis of the ms-like disease provoked by the myelin oligodendrocyte glycoprotein (mog), we have tested mice with an homologous disruption of the gene encoding tnf. |
1998-01-23 |
2023-08-12 |
mouse |
| N Kerlero de Rosbo, M Hoffman, I Mendel, I Yust, J Kaye, R Bakimer, S Flechter, O Abramsky, R Milo, A Karni, A Ben-Nu. Predominance of the autoimmune response to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis: reactivity to the extracellular domain of MOG is directed against three main regions. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394837. |
predominance of the autoimmune response to myelin oligodendrocyte glycoprotein (mog) in multiple sclerosis: reactivity to the extracellular domain of mog is directed against three main regions. |
1998-01-02 |
2023-08-12 |
human |
| N Kerlero de Rosbo, M Hoffman, I Mendel, I Yust, J Kaye, R Bakimer, S Flechter, O Abramsky, R Milo, A Karni, A Ben-Nu. Predominance of the autoimmune response to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis: reactivity to the extracellular domain of MOG is directed against three main regions. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394837. |
our previous analysis of the t cell reactivity to myelin antigens in a group of 24 patients with multiple sclerosis (ms) and 16 control individuals revealed that the autoimmune response to myelin oligodendrocyte glycoprotein (mog) predominates in ms over that to myelin basic protein (mbp), proteolipid protein or myelin-associated glycoprotein, suggesting a prevalent role for the autoimmune response to mog in the pathogenesis of ms. |
1998-01-02 |
2023-08-12 |
human |