| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Dahlman, E Wallström, R Weissert, M Storch, B Kornek, L Jacobsson, C Linington, H Luthman, H Lassmann, T Olsso. Linkage analysis of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in the rat identifies a locus controlling demyelination on chromosome 18. Human molecular genetics. vol 8. issue 12. 1999-12-14. PMID:10545597. |
we have recently established a chronic relapsing eae model characterized by inflammation and focal demyelination in the cns by immunizing a variety of rat strains with the cns-specific myelin oligodendrocyte glycoprotein (mog). |
1999-12-14 |
2023-08-12 |
rat |
| E Seboun, J R Oksenberg, A Rombos, K Usuku, D E Goodkin, R R Lincoln, M Wong, D Pham-Dinh, O Boesplug-Tanguy, R Carsique, R Fitoussi, C Gartioux, C Reyes, F Ribierre, S Faure, C Fizames, G Gyapay, J Weissenbach, A Dautigny, J B Rimmler, M E Garcia, M A Pericak-Vance, J L Haines, S L Hause. Linkage analysis of candidate myelin genes in familial multiple sclerosis. Neurogenetics. vol 2. issue 3. 1999-12-10. PMID:10541588. |
the present study was designed to analyze whether differences in genes that encode myelin proteins influence susceptibility to ms. we performed linkage analysis of ms to markers in chromosomal regions that include the genes encoding myelin basic protein (mbp), proteolipid protein (plp), myelin-associated glycoprotein (mag), oligodendrocyte myelin glycoprotein (omgp), and myelin oligodendrocyte glycoprotein (mog) in a well-characterized population of 65 multiplex ms families consisting of 399 total individuals, 169 affected with ms and 102 affected sibpairs. |
1999-12-10 |
2023-08-12 |
Not clear |
| M Reindl, C Linington, U Brehm, R Egg, E Dilitz, F Deisenhammer, W Poewe, T Berge. Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study. Brain : a journal of neurology. vol 122 ( Pt 11). 1999-12-10. PMID:10545390. |
in experimental animal models of multiple sclerosis demyelinating antibody responses are directed against the myelin oligodendrocyte glycoprotein (mog). |
1999-12-10 |
2023-08-12 |
human |
| Y Okuda, S Sakoda, H Fujimura, Y Saeki, T Kishimoto, T Yanagihar. IL-6 plays a crucial role in the induction phase of myelin oligodendrocyte glucoprotein 35-55 induced experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 101. issue 2. 1999-12-09. PMID:10580801. |
we investigated the role of il-6 in myelin oligodendrocyte glycoprotein (mog) peptide induced experimental autoimmune encephalomyelitis (eae) using il-6-deficient mice and found that il-6-deficient mice were resistant to active induction of eae, but that the treatment of those mice with il-6 during the preclinical phase caused typical eae. |
1999-12-09 |
2023-08-12 |
mouse |
| A Van der Goes, M Kortekaas, K Hoekstra, C D Dijkstra, S Amo. The role of anti-myelin (auto)-antibodies in the phagocytosis of myelin by macrophages. Journal of neuroimmunology. vol 101. issue 1. 1999-12-09. PMID:10580814. |
monoclonal antibodies directed to myelin basic protein (mbp)--clones 1, 12, 17, 22, 26, proteolipid protein (plp), galactocerebroside (galc) and myelin oligodendrocyte glycoprotein (mog)--clones y1, y4, y6, y7, y9, y10, y11 and z12 were incubated with purified murine myelin labeled with dii. |
1999-12-09 |
2023-08-12 |
Not clear |
| R Maron, W W Hancock, A Slavin, M Hattori, V Kuchroo, H L Weine. Genetic susceptibility or resistance to autoimmune encephalomyelitis in MHC congenic mice is associated with differential production of pro- and anti-inflammatory cytokines. International immunology. vol 11. issue 9. 1999-12-07. PMID:10464178. |
furthermore, nod mice which spontaneously develop diabetes are susceptible to eae induction with myelin oligodendrocyte glycoprotein (mog) 35-55, whereas a mhc congenic strain, iii, which also expresses i-a(g7) mhc haplotype does not develop diabetes and is also resistant to eae induction. |
1999-12-07 |
2023-08-12 |
mouse |
| T Kuhlmann, C Lucchinetti, U K Zettl, A Bitsch, H Lassmann, W Brüc. Bcl-2-expressing oligodendrocytes in multiple sclerosis lesions. Glia. vol 28. issue 1. 1999-11-22. PMID:10498820. |
double immunocytochemistry was performed with antibodies against bcl-2 and myelin oligodendrocyte glycoprotein (mog) to identify bcl-2-expressing oligodendrocytes within ms lesions from 43 patients. |
1999-11-22 |
2023-08-12 |
Not clear |
| H Gur, I Mendel, N Kerlero de Rosbo, A Ben-Nu. Effect of the bm12 class II mutation on proliferative and cytokine responses of encephalitogenic T cells in myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis. Journal of autoimmunity. vol 13. issue 1. 1999-11-04. PMID:10441162. |
effect of the bm12 class ii mutation on proliferative and cytokine responses of encephalitogenic t cells in myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis. |
1999-11-04 |
2023-08-12 |
mouse |
| H Gur, I Mendel, N Kerlero de Rosbo, A Ben-Nu. Effect of the bm12 class II mutation on proliferative and cytokine responses of encephalitogenic T cells in myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis. Journal of autoimmunity. vol 13. issue 1. 1999-11-04. PMID:10441162. |
we have studied the effect of this mutation on experimental autoimmune encephalomyelitis (eae), induced in h-2(b)mice by myelin oligodendrocyte glycoprotein (mog), and recently showed that mog 35-55 peptide (pmog 35-55), which represents the immunodominant encephalitogenic region for h-2(b)mice, is also a strong encephalitogen for h-2(bm12)mice. |
1999-11-04 |
2023-08-12 |
mouse |
| T T Chang, C Jabs, R A Sobel, V K Kuchroo, A H Sharp. Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis. The Journal of experimental medicine. vol 190. issue 5. 1999-10-14. PMID:10477557. |
in this study, the role of b7-cd28 costimulation and the relative importance of b7 costimulators for the induction and effector phases of experimental autoimmune encephalomyelitis (eae) induced by myelin oligodendrocyte glycoprotein (mog) peptide were examined. |
1999-10-14 |
2023-08-12 |
mouse |
| R Furlan, G Martino, F Galbiati, P L Poliani, S Smiroldo, A Bergami, G Desina, G Comi, R Flavell, M S Su, L Adorin. Caspase-1 regulates the inflammatory process leading to autoimmune demyelination. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 5. 1999-09-14. PMID:10452974. |
a reduction of eae incidence and severity is observed in caspase-1-deficient mice, depending on the immunogenicity and on the amount of the encephalitogenic myelin oligodendrocyte glycoprotein (mog) peptide used. |
1999-09-14 |
2023-08-12 |
mouse |
| D R Goddard, M Berry, A M But. In vivo actions of fibroblast growth factor-2 and insulin-like growth factor-I on oligodendrocyte development and myelination in the central nervous system. Journal of neuroscience research. vol 57. issue 1. 1999-08-04. PMID:10397637. |
in parallel experiments, amv were treated for western blot analysis to determine relative changes in expression of the myelin proteins 2', 3'-cyclic nucleotide 3'-phosphohydrolase (cnp) and myelin oligodendrocyte glycoprotein (mog), which, respectively, characterise early and late stages of myelin maturation. |
1999-08-04 |
2023-08-12 |
rat |
| A Stefferl, U Brehm, M Storch, D Lambracht-Washington, C Bourquin, K Wonigeit, H Lassmann, C Liningto. Myelin oligodendrocyte glycoprotein induces experimental autoimmune encephalomyelitis in the "resistant" Brown Norway rat: disease susceptibility is determined by MHC and MHC-linked effects on the B cell response. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 1. 1999-07-15. PMID:10384097. |
experimental autoimmune encephalomyelitis (eae) induced by active immunization with the myelin oligodendrocyte glycoprotein (mog) is an ab-mediated, t cell-dependent autoimmune disease that replicates the inflammatory demyelinating pathology of multiple sclerosis. |
1999-07-15 |
2023-08-12 |
rat |
| U Brehm, S J Piddlesden, M V Gardinier, C Liningto. Epitope specificity of demyelinating monoclonal autoantibodies directed against the human myelin oligodendrocyte glycoprotein (MOG). Journal of neuroimmunology. vol 97. issue 1-2. 1999-07-12. PMID:10408984. |
epitope specificity of demyelinating monoclonal autoantibodies directed against the human myelin oligodendrocyte glycoprotein (mog). |
1999-07-12 |
2023-08-12 |
human |
| V Jaquet, G Pfend, M Tosic, J M Matthie. Analysis of cis-acting sequences from the myelin oligodendrocyte glycoprotein promoter. Journal of neurochemistry. vol 73. issue 1. 1999-07-08. PMID:10386962. |
myelin oligodendrocyte glycoprotein (mog), a minor component of the myelin sheath, appears to be implicated in the late events of cns myelinogenesis. |
1999-07-08 |
2023-08-12 |
mouse |
| F Mokhtarian, Z Zhang, Y Shi, E Gonzales, R A Sobe. Molecular mimicry between a viral peptide and a myelin oligodendrocyte glycoprotein peptide induces autoimmune demyelinating disease in mice. Journal of neuroimmunology. vol 95. issue 1-2. 1999-05-17. PMID:10229114. |
to investigate the role of molecular mimicry in the pathogenesis of postviral demyelination, alignment algorithms were used and amino acid homologies between immunogenic epitopes of sfv and myelin autoantigens, myelin basic protein (mbp), myelin proteolipid protein (plp) and myelin oligodendrocyte glycoprotein (mog) were identified. |
1999-05-17 |
2023-08-12 |
mouse |
| S Weerth, T Berger, H Lassmann, C Liningto. Encephalitogenic and neuritogenic T cell responses to the myelin-associated glycoprotein (MAG) in the Lewis rat. Journal of neuroimmunology. vol 95. issue 1-2. 1999-05-17. PMID:10229126. |
co-transfer of mp1.1 (a.a. sequence 20-34)-specific t cells with the myelin oligodendrocyte glycoprotein (mog)-specific monoclonal antibody 8-18c5 enhanced disease severity and induced widespread demyelination in the cns. |
1999-05-17 |
2023-08-12 |
rat |
| A Karni, R Bakimer-Kleiner, O Abramsky, A Ben-Nu. Elevated levels of antibody to myelin oligodendrocyte glycoprotein is not specific for patients with multiple sclerosis. Archives of neurology. vol 56. issue 3. 1999-04-14. PMID:10190821. |
to evaluate the presence and specificity of anti-myelin oligodendrocyte glycoprotein (mog) antibody in the cerebrospinal fluid and plasma of patients with multiple sclerosis (ms). |
1999-04-14 |
2023-08-12 |
Not clear |
| H I McFarland, A A Lobito, M M Johnson, J T Nyswaner, J A Frank, G R Palardy, N Tresser, C P Genain, J P Mueller, L A Matis, M J Lenard. Determinant spreading associated with demyelination in a nonhuman primate model of multiple sclerosis. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 4. 1999-04-13. PMID:9973519. |
demyelination was associated with spreading to myelin oligodendrocyte glycoprotein (mog) determinants that generated anti-mog serum abs and ig deposition in central nervous system white matter lesions. |
1999-04-13 |
2023-08-12 |
marmoset |
| H P Eugster, K Frei, R Bachmann, H Bluethmann, H Lassmann, A Fontan. Severity of symptoms and demyelination in MOG-induced EAE depends on TNFR1. European journal of immunology. vol 29. issue 2. 1999-03-16. PMID:10064079. |
in wild-type (wt) mice immunized with myelin oligodendrocyte glycoprotein (mog) peptide 35-55 the clinical course is characterized by an acute disease onset with peak disease scores and a consecutive chronic phase lasting up to 60 days. |
1999-03-16 |
2023-08-12 |
mouse |