Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M Ichikawa, C S Koh, Y Inaba, C Seki, A Inoue, M Itoh, Y Ishihara, C C Bernard, A Komiyam. IgG subclass switching is associated with the severity of experimental autoimmune encephalomyelitis induced with myelin oligodendrocyte glycoprotein peptide in NOD mice. Cellular immunology. vol 191. issue 2. 1999-03-15. PMID:9973531. |
we have recently shown that a single dose of the myelin oligodendrocyte glycoprotein (mog) peptide 35-55 produces a relapsing-remitting demyelinating disease similar to multiple sclerosis (ms) in lewis rats. |
1999-03-15 |
2023-08-12 |
mouse |
M K Storch, A Stefferl, U Brehm, R Weissert, E Wallström, M Kerschensteiner, T Olsson, C Linington, H Lassman. Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology. Brain pathology (Zurich, Switzerland). vol 8. issue 4. 1999-01-29. PMID:9804377. |
recently, however, a new model of myelin oligodendrocyte glycoprotein (mog) induced autoimmune encephalomyelitis became available, which, in a very standardized and predictable way, leads to chronic (relapsing or progressive) disease and widespread cns demyelination. |
1999-01-29 |
2023-08-12 |
rat |
B della Gaspera, D Pham-Dinh, G Roussel, J L Nussbaum, A Dautign. Membrane topology of the myelin/oligodendrocyte glycoprotein. European journal of biochemistry. vol 258. issue 2. 1999-01-28. PMID:9874214. |
myelin/oligodendrocyte glycoprotein (mog), a specific component of the mammalian central nervous system, is located on the surface of the oligodendrocyte plasma membrane and the outermost lamellae of mature myelin; it is expressed during the latter steps of myelinogenesis. |
1999-01-28 |
2023-08-12 |
Not clear |
E B Samoilova, J L Horton, B Hilliard, T S Liu, Y Che. IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 12. 1999-01-22. PMID:9862671. |
we found that il-6-deficient mice were completely resistant to eae induced by myelin oligodendrocyte glycoprotein (mog), whereas il-6-competent control mice developed eae characterized by focal inflammation and demyelination in the central nervous system and deficiency in neurologic functions. |
1999-01-22 |
2023-08-12 |
mouse |
T G Johns, C C Bernar. The structure and function of myelin oligodendrocyte glycoprotein. Journal of neurochemistry. vol 72. issue 1. 1999-01-21. PMID:9886048. |
myelin oligodendrocyte glycoprotein (mog) is a quantitatively minor component of cns myelin whose function remains relatively unknown. |
1999-01-21 |
2023-08-12 |
mouse |
T G Johns, C C Bernar. The structure and function of myelin oligodendrocyte glycoprotein. Journal of neurochemistry. vol 72. issue 1. 1999-01-21. PMID:9886048. |
on the basis of this knowledge we suggest three possible functions for mog: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. |
1999-01-21 |
2023-08-12 |
mouse |
M N Grote, W Klitz, G Thomso. Constrained disequilibrium values and hitchhiking in a three-locus system. Genetics. vol 150. issue 3. 1999-01-07. PMID:9799280. |
we present a microsatellite data set from human chromosome 6, in which constrained disequilibrium values suggest the action of selection in a region containing the human leukocyte antigen (hla)-a and myelin oligodendrocyte glycoprotein (mog) loci. |
1999-01-07 |
2023-08-12 |
human |
A Slavin, C Ewing, J Liu, M Ichikawa, J Slavin, C C Bernar. Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. Autoimmunity. vol 28. issue 2. 1998-12-29. PMID:9771980. |
myelin oligodendrocyte glycoprotein (mog) is postulated to be a target autoantigen in multiple sclerosis (ms). |
1998-12-29 |
2023-08-12 |
mouse |
E Wallström, M Khademi, M Andersson, R Weissert, C Linington, T Olsso. Increased reactivity to myelin oligodendrocyte glycoprotein peptides and epitope mapping in HLA DR2(15)+ multiple sclerosis. European journal of immunology. vol 28. issue 10. 1998-12-15. PMID:9808202. |
myelin oligodendrocyte glycoprotein (mog) is a surface-exposed minor myelin component that is a prime candidate autoantigen. |
1998-12-15 |
2023-08-12 |
Not clear |
P Hjelmström, A E Juedes, J Fjell, N H Ruddl. B-cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitization. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 9. 1998-11-18. PMID:9794370. |
myelin oligodendrocyte glycoprotein (mog) induced experimental allergic encephalomyelitis (eae) is an animal model for the central nervous system disease multiple sclerosis (ms). |
1998-11-18 |
2023-08-12 |
mouse |
N K de Rosbo, A Ben-Nu. T-cell responses to myelin antigens in multiple sclerosis; relevance of the predominant autoimmune reactivity to myelin oligodendrocyte glycoprotein. Journal of autoimmunity. vol 11. issue 4. 1998-11-05. PMID:9776706. |
more relevant to ms pathogenesis may be, as we outlined in this review, the autoimmune reactivity directed against minor myelin proteins, in particular the cns-specific myelin oligodendrocyte glycoprotein (mog). |
1998-11-05 |
2023-08-12 |
Not clear |
E B Samoilova, J L Horton, Y Che. Acceleration of experimental autoimmune encephalomyelitis in interleukin-10-deficient mice: roles of interleukin-10 in disease progression and recovery. Cellular immunology. vol 188. issue 2. 1998-10-29. PMID:9756642. |
we found that il-10- but not il-4-deficient mice had accelerated eae following immunization with myelin oligodendrocyte glycoprotein (mog). |
1998-10-29 |
2023-08-12 |
mouse |
Y Okuda, S Sakoda, C C Bernard, T Yanagihar. The development of autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein is associated with an upregulation of both proinflammatory and immunoregulatory cytokines in the central nervous system. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 18. issue 6. 1998-10-16. PMID:9660249. |
we report here that gene expression for both proinflammatory and immunoregulatory cytokines increased during the course of disease in the cns of mice with myelin oligodendrocyte glycoprotein (mog)-induced nonrelapsing eae. |
1998-10-16 |
2023-08-12 |
mouse |
P Hjelmström, J E Penzotti, R M Henne, T P Lybran. A molecular model of myelin oligodendrocyte glycoprotein. Journal of neurochemistry. vol 71. issue 4. 1998-10-14. PMID:9751210. |
myelin oligodendrocyte glycoprotein (mog) is a protein on the surface of myelin sheaths. |
1998-10-14 |
2023-08-12 |
mouse |
Y Okuda, C C Bernard, H Fujimura, T Yanagihara, S Sakod. Fas has a crucial role in the progression of experimental autoimmune encephalomyelitis. Molecular immunology. vol 35. issue 5. 1998-09-30. PMID:9747891. |
the frequency of myelin oligodendrocyte glycoprotein (mog)-induced eae in b6.lpr mice was significantly lower than that in b6 mice (19% vs 94%). |
1998-09-30 |
2023-08-12 |
mouse |
Y Okuda, S Sakoda, C C Bernard, H Fujimura, Y Saeki, T Kishimoto, T Yanagihar. IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein. International immunology. vol 10. issue 5. 1998-09-08. PMID:9645618. |
the role of il-6 in experimental autoimmune encephalomyelitis (eae) provoked by myelin oligodendrocyte glycoprotein (mog) was investigated using il-6-deficient mice. |
1998-09-08 |
2023-08-12 |
mouse |
T Litzenburger, R Fässler, J Bauer, H Lassmann, C Linington, H Wekerle, A Iglesia. B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice. The Journal of experimental medicine. vol 188. issue 1. 1998-08-14. PMID:9653093. |
we studied the cellular basis of self tolerance of b cells specific for brain autoantigens using transgenic mice engineered to produce high titers of autoantibodies against the myelin oligodendrocyte glycoprotein (mog), a surface component of central nervous system myelin. |
1998-08-14 |
2023-08-12 |
mouse |
H P Eugster, K Frei, M Kopf, H Lassmann, A Fontan. IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. European journal of immunology. vol 28. issue 7. 1998-08-13. PMID:9692887. |
experimental autoimmune encephalomyelitis (eae) is induced by immunization with myelin components including myelin oligodendrocyte glycoprotein (mog). |
1998-08-13 |
2023-08-12 |
mouse |
I Dahlman, J C Lorentzen, K L de Graaf, A Stefferl, C Linington, H Luthman, T Olsso. Quantitative trait loci disposing for both experimental arthritis and encephalomyelitis in the DA rat; impact on severity of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis and antibody isotype pattern. European journal of immunology. vol 28. issue 7. 1998-08-13. PMID:9692888. |
we have investigated whether five non-mhc qtl controlling susceptibility to experimental arthritis in the da rat also influence myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) in an f2 intercross between inbred da and pvg.rt1a rats. |
1998-08-13 |
2023-08-12 |
rat |
I Mews, M Bergmann, S Bunkowski, F Gullotta, W Brüc. Oligodendrocyte and axon pathology in clinically silent multiple sclerosis lesions. Multiple sclerosis (Houndmills, Basingstoke, England). vol 4. issue 2. 1998-07-10. PMID:9599334. |
oligodendrocytes were identified by immunocytochemistry for myelin oligodendrocyte glycoprotein (mog) and in situ hybridization for proteolipid protein (plp) mrna. |
1998-07-10 |
2023-08-12 |
Not clear |