| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Adelmann, J Wood, I Benzel, P Fiori, H Lassmann, J M Matthieu, M V Gardinier, K Dornmair, C Liningto. The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat. Journal of neuroimmunology. vol 63. issue 1. 1996-02-27. PMID:8557821. |
using a highly purified recombinant protein, mmog, we demonstrated that autoimmune responses to the n-terminal domain (a.a 1-125) of the myelin oligodendrocyte glycoprotein (mog) induce an acute demyelinating variant of experimental autoimmune encephalomyelitis (eae) in the lewis rat. |
1996-02-27 |
2023-08-12 |
rat |
| J C Lorentzen, S Issazadeh, M Storch, M I Mustafa, H Lassman, C Linington, L Klareskog, T Olsso. Protracted, relapsing and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete Freund's adjuvant. Journal of neuroimmunology. vol 63. issue 2. 1996-02-21. PMID:8550817. |
the induction of spr-eae was associated with humoral autoreactivity to myelin oligodendrocyte glycoprotein (mog) and cellular autoreactivity to the rat myelin basic protein (mbp) peptides 69-87 and 87-101. |
1996-02-21 |
2023-08-12 |
rat |
| M P Roth, L Malfroy, C Offer, J Sevin, G Enault, N Borot, P Pontarotti, H Coppi. The human myelin oligodendrocyte glycoprotein (MOG) gene: complete nucleotide sequence and structural characterization. Genomics. vol 28. issue 2. 1996-02-01. PMID:8530032. |
the human myelin oligodendrocyte glycoprotein (mog) gene: complete nucleotide sequence and structural characterization. |
1996-02-01 |
2023-08-12 |
human |
| M P Roth, L Malfroy, C Offer, J Sevin, G Enault, N Borot, P Pontarotti, H Coppi. The human myelin oligodendrocyte glycoprotein (MOG) gene: complete nucleotide sequence and structural characterization. Genomics. vol 28. issue 2. 1996-02-01. PMID:8530032. |
human myelin oligodendrocyte glycoprotein (mog), a myelin component of the central nervous system, is a candidate target antigen for autoimmune-mediated demyelination. |
1996-02-01 |
2023-08-12 |
human |
| L Malfroy, C Viratelle, H Coppin, N Borot, M P Rot. Polymorphic tri- and tetranucleotide repeats in exons 1 and 8 of the myelin oligodendrocyte glycoprotein (MOG) gene. Human genetics. vol 96. issue 6. 1996-01-22. PMID:8522338. |
polymorphic tri- and tetranucleotide repeats in exons 1 and 8 of the myelin oligodendrocyte glycoprotein (mog) gene. |
1996-01-22 |
2023-08-12 |
Not clear |
| L Malfroy, C Viratelle, H Coppin, N Borot, M P Rot. Polymorphic tri- and tetranucleotide repeats in exons 1 and 8 of the myelin oligodendrocyte glycoprotein (MOG) gene. Human genetics. vol 96. issue 6. 1996-01-22. PMID:8522338. |
polymorphic (ctc)n and (taaa)n sequences were identified in exons 1 and 8 of the myelin oligodendrocyte glycoprotein (mog) gene. |
1996-01-22 |
2023-08-12 |
Not clear |
| M P Roth, L Dolbois, N Borot, P Pontarotti, M Clanet, H Coppi. Myelin oligodendrocyte glycoprotein (MOG) gene polymorphisms and multiple sclerosis: no evidence of disease association with MOG. Journal of neuroimmunology. vol 61. issue 2. 1995-11-30. PMID:7593547. |
myelin oligodendrocyte glycoprotein (mog) gene polymorphisms and multiple sclerosis: no evidence of disease association with mog. |
1995-11-30 |
2023-08-12 |
Not clear |
| M P Roth, L Dolbois, N Borot, P Pontarotti, M Clanet, H Coppi. Myelin oligodendrocyte glycoprotein (MOG) gene polymorphisms and multiple sclerosis: no evidence of disease association with MOG. Journal of neuroimmunology. vol 61. issue 2. 1995-11-30. PMID:7593547. |
the region surrounding the myelin oligodendrocyte glycoprotein (mog) gene, located telomeric to the major histocompatibility complex on chromosome 6, was shown to contain three highly informative microsatellites. |
1995-11-30 |
2023-08-12 |
Not clear |
| I Mendel, N Kerlero de Rosbo, A Ben-Nu. A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogenic T cells. European journal of immunology. vol 25. issue 7. 1995-08-29. PMID:7621871. |
a predominant response to myelin oligodendrocyte glycoprotein (mog) was recently observed in patients with multiple sclerosis (ms). |
1995-08-29 |
2023-08-12 |
mouse |
| N Schaeren-Wiemers, C Schaefer, D M Valenzuela, G D Yancopoulos, M E Schwa. Identification of new oligodendrocyte- and myelin-specific genes by a differential screening approach. Journal of neurochemistry. vol 65. issue 1. 1995-07-26. PMID:7790852. |
four of these genes are exclusively expressed by oligodendrocytes: three of these are not related to known genes, whereas one encodes the myelin oligodendrocyte glycoprotein (mog). |
1995-07-26 |
2023-08-12 |
rat |
| A A Hilton, A J Slavin, D J Hilton, C C Bernar. Characterization of cDNA and genomic clones encoding human myelin oligodendrocyte glycoprotein. Journal of neurochemistry. vol 65. issue 1. 1995-07-26. PMID:7790876. |
myelin oligodendrocyte glycoprotein (mog) is a transmembrane protein expressed only in the cns and is a possible target autoantigen in multiple sclerosis (ms). |
1995-07-26 |
2023-08-12 |
human |
| I Huitinga, S R Ruuls, S Jung, N Van Rooijen, H P Hartung, C D Dijkstr. Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats. Clinical and experimental immunology. vol 100. issue 2. 1995-06-15. PMID:7743675. |
t cell-eae with pronounced demyelination as induced by an additionally injected moab directed against myelin oligodendrocyte glycoprotein (mog) was also significantly ameliorated after macrophage depletion. |
1995-06-15 |
2023-08-12 |
rat |
| C Fressinaud, J M Vallat, G Labourdett. Basic fibroblast growth factor down-regulates myelin basic protein gene expression and alters myelin compaction of mature oligodendrocytes in vitro. Journal of neuroscience research. vol 40. issue 3. 1995-06-14. PMID:7745622. |
moreover, the percentage of oligodendrocytes labelled with anti-mbp antibodies decreased by 50%, as well as that of oligodendrocytes expressing myelin oligodendrocyte glycoprotein (mog), whereas proteolipid protein (plp) immunolabelled cells were less affected. |
1995-06-14 |
2023-08-12 |
rat |
| N Kerlero de Rosbo, I Mendel, A Ben-Nu. Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)-derived peptide: preliminary analysis of MOG T cell epitopes. European journal of immunology. vol 25. issue 4. 1995-06-07. PMID:7737302. |
chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in pl/j mice by myelin oligodendrocyte glycoprotein (mog)-derived peptide: preliminary analysis of mog t cell epitopes. |
1995-06-07 |
2023-08-12 |
mouse |
| N Kerlero de Rosbo, I Mendel, A Ben-Nu. Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)-derived peptide: preliminary analysis of MOG T cell epitopes. European journal of immunology. vol 25. issue 4. 1995-06-07. PMID:7737302. |
however, there is increasing evidence to suggest that autoimmune reactivity against the quantitatively minor myelin component, myelin oligodendrocyte glycoprotein (mog), can also play a role in the pathogenicity of ms. we recently demonstrated a predominant response to mog by peripheral blood lymphocytes from patients with ms tested for their reactivity against various myelin antigens, including mbp and plp. |
1995-06-07 |
2023-08-12 |
mouse |
| S Amor, N Groome, C Linington, M M Morris, K Dornmair, M V Gardinier, J M Matthieu, D Bake. Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice. Journal of immunology (Baltimore, Md. : 1950). vol 153. issue 10. 1994-12-07. PMID:7525700. |
a recombinant protein corresponding to the ig-like domain of myelin oligodendrocyte glycoprotein (mog) and synthetic 15-mer peptides of the whole mog molecule with eight amino acid overlaps were screened for their ability to induce experimental allergic encephalomyelitis (eae) in biozzi ab/h (h-2dq1) and sjl (h-2s) mice. |
1994-12-07 |
2023-08-12 |
mouse |
| C Z Lu, S Fredrikson, B G Xiao, H Lin. Interleukin-2 secreting cells in multiple sclerosis and controls. Journal of the neurological sciences. vol 120. issue 1. 1994-02-22. PMID:8289087. |
numbers of il-2 secreting cells were higher in ms patients compared to patients with am + th after stimulation with myelin proteolipid protein (plp), myelin associated glycoprotein (mag) and myelin oligodendrocyte glycoprotein (mog), but not after stimulation with myelin basic protein (mbp). |
1994-02-22 |
2023-08-12 |
Not clear |
| N Kerlero de Rosbo, R Milo, M B Lees, D Burger, C C Bernard, A Ben-Nu. Reactivity to myelin antigens in multiple sclerosis. Peripheral blood lymphocytes respond predominantly to myelin oligodendrocyte glycoprotein. The Journal of clinical investigation. vol 92. issue 6. 1994-01-12. PMID:7504688. |
although t cell responses to the quantitatively major myelin proteins, myelin basic protein (mbp) and proteolipid protein (plp), are likely to be of importance in the course of multiple sclerosis (ms), cell-mediated autoimmune responses to other myelin antigens, in particular quantitatively minor myelin antigens, such as myelin-associated glycoprotein (mag) and the central nervous system-specific myelin oligodendrocyte glycoprotein (mog), could also play a prevalent role in disease initiation or progression. |
1994-01-12 |
2023-08-12 |
Not clear |
| S Abo, C C Bernard, M Webb, T G Johns, A Alafaci, L D Ward, R J Simpson, N Kerlero de Rosb. Preparation of highly purified human myelin oligodendrocyte glycoprotein in quantities sufficient for encephalitogenicity and immunogenicity studies. Biochemistry and molecular biology international. vol 30. issue 5. 1993-11-26. PMID:8220243. |
myelin oligodendrocyte glycoprotein, (mog), a quantitatively minor central nervous system (cns) myelin component, is a candidate target antigen for autoimmune-mediated demyelination. |
1993-11-26 |
2023-08-12 |
human |
| M V Gardinier, J M Matthie. Cloning and cDNA sequence analysis of myelin/oligodendrocyte glycoprotein: a novel member of the immunoglobulin gene superfamily. Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985). vol 144. issue 3. 1993-08-17. PMID:7687365. |
myelin/oligodendrocyte glycoprotein (mog) is a cns-specific protein that has been identified on the external myelin sheath and oligodendrocyte processes. |
1993-08-17 |
2023-08-12 |
rat |