| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Issazadeh, K Abdallah, T Chitnis, A Chandraker, A D Wells, L A Turka, M H Sayegh, S J Khour. Role of passive T-cell death in chronic experimental autoimmune encephalomyelitis. The Journal of clinical investigation. vol 105. issue 8. 2000-05-19. PMID:10772655. |
we found that mice transgenic for bcl-x(l) have an earlier onset and a more chronic form of eae induced by myelin oligodendrocyte glycoprotein (mog) peptide 35-55 compared with wild-type littermate mice. |
2000-05-19 |
2023-08-12 |
mouse |
| J J Bajramović, A C Plomp, A v Goes, C Koevoets, J Newcombe, M L Cuzner, J M van Noor. Presentation of alpha B-crystallin to T cells in active multiple sclerosis lesions: an early event following inflammatory demyelination. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 8. 2000-05-09. PMID:10754336. |
in 3 of 10 active ms lesions, alpha b-crystallin could be detected inside phagocytic vesicles of perivascular macrophages, colocalizing with myelin basic protein and myelin oligodendrocyte glycoprotein (mog). |
2000-05-09 |
2023-08-12 |
human |
| V H Secor, W E Secor, C A Gutekunst, M A Brow. Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis. The Journal of experimental medicine. vol 191. issue 5. 2000-04-04. PMID:10704463. |
using a myelin oligodendrocyte glycoprotein (mog)-induced model of acute eae, we show that mast cell-deficient w/w(v) mice exhibit significantly reduced disease incidence, delayed disease onset, and decreased mean clinical scores when compared with their wild-type congenic littermates. |
2000-04-04 |
2023-08-12 |
mouse |
| F Mattner, S Smiroldo, F Galbiati, M Muller, P Di Lucia, P L Poliani, G Martino, P Panina-Bordignon, L Adorin. Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D(3). European journal of immunology. vol 30. issue 2. 2000-03-14. PMID:10671205. |
administration of 1,25(oh)(2)d(3) or its analogue prevents chronic-relapsing experimental allergic encephalomyelitis (cr-eae) induced by the myelin oligodendrocyte glycoprotein (mog) peptide 35 - 55 (mog(35 - 55)) in biozzi ab / h mice. |
2000-03-14 |
2023-08-12 |
mouse |
| E Pál, T Yamamura, T Tabir. Autonomic regulation of experimental autoimmune encephalomyelitis in IL-4 knockout mice. Journal of neuroimmunology. vol 100. issue 1-2. 2000-03-09. PMID:10695725. |
when actively sensitized with myelin oligodendrocyte glycoprotein (mog)35-55 peptide, control b6 mice developed a mild form of eae with full recovery. |
2000-03-09 |
2023-08-12 |
mouse |
| G Wolswij. Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis. Brain : a journal of neurology. vol 123 ( Pt 1). 2000-02-14. PMID:10611125. |
sections of post-mortem multiple sclerosis tissue were therefore immunolabelled with antibodies to galactocerebroside (galc), the first oligodendrocyte-specific molecule to be expressed by differentiating oligodendrocyte precursor cells, and myelin oligodendrocyte glycoprotein (mog), a marker for mature oligodendrocytes. |
2000-02-14 |
2023-08-12 |
human |
| A M Butt, M Ibrahim, N Gregson, M Berr. Differential expression of the L- and S-isoforms of myelin associated glycoprotein (MAG) in oligodendrocyte unit phenotypes in the adult rat anterior medullary velum. Journal of neurocytology. vol 27. issue 4. 2000-02-08. PMID:10640185. |
in this study, we have determined the expression of myelin proteins in oligodendrocyte unit phenotypes i-iv, which myelinate fibres ranging in diameter from 0.3-12 microns diameter in the amv, by using double immunolabelling for rip, which labels entire units, and mbp, plp, myelin oligodendrocyte glycoprotein (mog), l-mag and s-mag. |
2000-02-08 |
2023-08-12 |
rat |
| M Ichikawa, C S Koh, A Inoue, J Tsuyusaki, M Yamazaki, Y Inaba, Y Sekiguchi, M Itoh, H Yagita, A Komiyam. Anti-IL-12 antibody prevents the development and progression of multiple sclerosis-like relapsing--remitting demyelinating disease in NOD mice induced with myelin oligodendrocyte glycoprotein peptide. Journal of neuroimmunology. vol 102. issue 1. 2000-02-03. PMID:10626667. |
treatment with monoclonal anti-il-12 antibody injected on day 0, 7 and 10 after immunization with myelin oligodendrocyte glycoprotein (mog) peptide 35-55 in nod mice resulted in significant suppression of the development and the severity of the chronic relapsing-remitting experimental autoimmune encephalomyelitis (eae) both clinically and histologically. |
2000-02-03 |
2023-08-12 |
mouse |
| C Lucchinetti, W Brück, J Parisi, B Scheithauer, M Rodriguez, H Lassman. A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases. Brain : a journal of neurology. vol 122 ( Pt 12). 2000-01-20. PMID:10581222. |
in inactive areas, an increased number of ogs expressing proteolipid protein (plp) mrna compared with those expressing myelin oligodendrocyte glycoprotein (mog) suggested these cells may have been derived from the progenitor pool. |
2000-01-20 |
2023-08-12 |
Not clear |
| A E Juedes, P Hjelmström, C M Bergman, A L Neild, N H Ruddl. Kinetics and cellular origin of cytokines in the central nervous system: insight into mechanisms of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 1. 2000-01-19. PMID:10605038. |
experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein (mog) in c57bl/6 (h-2b) mice is characterized by early (day 12) acute paralysis, followed by a sustained chronic clinical course that gradually stabilizes. |
2000-01-19 |
2023-08-12 |
mouse |
| T W Spahn, S Issazadah, A J Salvin, H L Weine. Decreased severity of myelin oligodendrocyte glycoprotein peptide 33 - 35-induced experimental autoimmune encephalomyelitis in mice with a disrupted TCR delta chain gene. European journal of immunology. vol 29. issue 12. 2000-01-04. PMID:10602017. |
immunization of c57bl / 6 mice with myelin oligodendrocyte glycoprotein (mog) peptide (p) 35 - 55 induces chronic experimental autoimmune encephalomyelitis (eae). |
2000-01-04 |
2023-08-12 |
mouse |
| J A Lyons, M San, M P Happ, A H Cros. B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptide. European journal of immunology. vol 29. issue 11. 1999-12-23. PMID:10556797. |
to further characterize the role of b cells in experimental allergic encephalomyelitis (eae), wild-type and b cell-deficient c57bl/6 mice were immunized with either a recombinant form of myelin oligodendrocyte glycoprotein (mog) or with the encephalitogenic mog(35-55) peptide. |
1999-12-23 |
2023-08-12 |
mouse |
| I Dahlman, E Wallström, R Weissert, M Storch, B Kornek, L Jacobsson, C Linington, H Luthman, H Lassmann, T Olsso. Linkage analysis of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in the rat identifies a locus controlling demyelination on chromosome 18. Human molecular genetics. vol 8. issue 12. 1999-12-14. PMID:10545597. |
we have recently established a chronic relapsing eae model characterized by inflammation and focal demyelination in the cns by immunizing a variety of rat strains with the cns-specific myelin oligodendrocyte glycoprotein (mog). |
1999-12-14 |
2023-08-12 |
rat |
| E Seboun, J R Oksenberg, A Rombos, K Usuku, D E Goodkin, R R Lincoln, M Wong, D Pham-Dinh, O Boesplug-Tanguy, R Carsique, R Fitoussi, C Gartioux, C Reyes, F Ribierre, S Faure, C Fizames, G Gyapay, J Weissenbach, A Dautigny, J B Rimmler, M E Garcia, M A Pericak-Vance, J L Haines, S L Hause. Linkage analysis of candidate myelin genes in familial multiple sclerosis. Neurogenetics. vol 2. issue 3. 1999-12-10. PMID:10541588. |
the present study was designed to analyze whether differences in genes that encode myelin proteins influence susceptibility to ms. we performed linkage analysis of ms to markers in chromosomal regions that include the genes encoding myelin basic protein (mbp), proteolipid protein (plp), myelin-associated glycoprotein (mag), oligodendrocyte myelin glycoprotein (omgp), and myelin oligodendrocyte glycoprotein (mog) in a well-characterized population of 65 multiplex ms families consisting of 399 total individuals, 169 affected with ms and 102 affected sibpairs. |
1999-12-10 |
2023-08-12 |
Not clear |
| M Reindl, C Linington, U Brehm, R Egg, E Dilitz, F Deisenhammer, W Poewe, T Berge. Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study. Brain : a journal of neurology. vol 122 ( Pt 11). 1999-12-10. PMID:10545390. |
in experimental animal models of multiple sclerosis demyelinating antibody responses are directed against the myelin oligodendrocyte glycoprotein (mog). |
1999-12-10 |
2023-08-12 |
human |
| Y Okuda, S Sakoda, H Fujimura, Y Saeki, T Kishimoto, T Yanagihar. IL-6 plays a crucial role in the induction phase of myelin oligodendrocyte glucoprotein 35-55 induced experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 101. issue 2. 1999-12-09. PMID:10580801. |
we investigated the role of il-6 in myelin oligodendrocyte glycoprotein (mog) peptide induced experimental autoimmune encephalomyelitis (eae) using il-6-deficient mice and found that il-6-deficient mice were resistant to active induction of eae, but that the treatment of those mice with il-6 during the preclinical phase caused typical eae. |
1999-12-09 |
2023-08-12 |
mouse |
| A Van der Goes, M Kortekaas, K Hoekstra, C D Dijkstra, S Amo. The role of anti-myelin (auto)-antibodies in the phagocytosis of myelin by macrophages. Journal of neuroimmunology. vol 101. issue 1. 1999-12-09. PMID:10580814. |
monoclonal antibodies directed to myelin basic protein (mbp)--clones 1, 12, 17, 22, 26, proteolipid protein (plp), galactocerebroside (galc) and myelin oligodendrocyte glycoprotein (mog)--clones y1, y4, y6, y7, y9, y10, y11 and z12 were incubated with purified murine myelin labeled with dii. |
1999-12-09 |
2023-08-12 |
Not clear |
| R Maron, W W Hancock, A Slavin, M Hattori, V Kuchroo, H L Weine. Genetic susceptibility or resistance to autoimmune encephalomyelitis in MHC congenic mice is associated with differential production of pro- and anti-inflammatory cytokines. International immunology. vol 11. issue 9. 1999-12-07. PMID:10464178. |
furthermore, nod mice which spontaneously develop diabetes are susceptible to eae induction with myelin oligodendrocyte glycoprotein (mog) 35-55, whereas a mhc congenic strain, iii, which also expresses i-a(g7) mhc haplotype does not develop diabetes and is also resistant to eae induction. |
1999-12-07 |
2023-08-12 |
mouse |
| T Kuhlmann, C Lucchinetti, U K Zettl, A Bitsch, H Lassmann, W Brüc. Bcl-2-expressing oligodendrocytes in multiple sclerosis lesions. Glia. vol 28. issue 1. 1999-11-22. PMID:10498820. |
double immunocytochemistry was performed with antibodies against bcl-2 and myelin oligodendrocyte glycoprotein (mog) to identify bcl-2-expressing oligodendrocytes within ms lesions from 43 patients. |
1999-11-22 |
2023-08-12 |
Not clear |
| H Gur, I Mendel, N Kerlero de Rosbo, A Ben-Nu. Effect of the bm12 class II mutation on proliferative and cytokine responses of encephalitogenic T cells in myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis. Journal of autoimmunity. vol 13. issue 1. 1999-11-04. PMID:10441162. |
effect of the bm12 class ii mutation on proliferative and cytokine responses of encephalitogenic t cells in myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis. |
1999-11-04 |
2023-08-12 |
mouse |