| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoshinobu Okuda, Misa Okuda, Claude C A Bernar. Gender does not influence the susceptibility of C57BL/6 mice to develop chronic experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein. Immunology letters. vol 81. issue 1. 2002-08-06. PMID:11841842. |
in contrast, we report here that no significant difference between female mice and male mice with myelin oligodendrocyte glycoprotein (mog)-induced eae was observed in the incidence of disease, clinical course, histological findings in the cns, t cell response and cytokine production of spleen cells to mog, and anti-mog igg level in serum. |
2002-08-06 |
2023-08-12 |
mouse |
| I A Scarisbrick, S I Blaber, C F Lucchinetti, C P Genain, M Blaber, M Rodrigue. Activity of a newly identified serine protease in CNS demyelination. Brain : a journal of neurology. vol 125. issue Pt 6. 2002-07-24. PMID:12023317. |
to determine the potential activity of msp in cns demyelination, we examined its expression in multiple sclerosis lesions and in two animal models of multiple sclerosis: theiler's murine encephalomyelitis virus (tmev) and myelin oligodendrocyte glycoprotein (mog)-induced experimental allergic encephalomyelitis (eae) in marmosets. |
2002-07-24 |
2023-08-12 |
Not clear |
| Ming-Chao Zhong, Nicole Kerlero de Rosbo, Avraham Ben-Nu. Multiantigen/multiepitope-directed immune-specific suppression of "complex autoimmune encephalomyelitis" by a novel protein product of a synthetic gene. The Journal of clinical investigation. vol 110. issue 1. 2002-07-24. PMID:12093891. |
a synthetic gene was constructed to encode selected disease-relevant epitopes of myelin basic protein (mbp), proteolipid protein (plp), and myelin oligodendrocyte glycoprotein (mog). |
2002-07-24 |
2023-08-12 |
human |
| Ralf A Linker, Mathias Mäurer, Stefanie Gaupp, Rudolf Martini, Bettina Holtmann, Ralf Giess, Peter Rieckmann, Hans Lassmann, Klaus V Toyka, Michael Sendtner, Ralf Gol. CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation. Nature medicine. vol 8. issue 6. 2002-06-26. PMID:12042814. |
to investigate the role of endogenous cntf in inflammatory demyelinating disease, we studied myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) in cntf-deficient and wild-type c57bl/6 mice. |
2002-06-26 |
2023-08-12 |
mouse |
| Niklas K U Koehler, Claude P Genain, Barbara Giesser, Stephen L Hause. The human T cell response to myelin oligodendrocyte glycoprotein: a multiple sclerosis family-based study. Journal of immunology (Baltimore, Md. : 1950). vol 168. issue 11. 2002-06-12. PMID:12023398. |
myelin oligodendrocyte glycoprotein (mog) is an encephalitogenic myelin protein and a likely autoantigen in human multiple sclerosis (ms). |
2002-06-12 |
2023-08-12 |
human |
| Margaret M Morris-Downes, Paul A Smith, Jon L Rundle, Sara J Piddlesden, David Baker, Danielle Pham-Dinh, Nicole Heijmans, Sandra Amo. Pathological and regulatory effects of anti-myelin antibodies in experimental allergic encephalomyelitis in mice. Journal of neuroimmunology. vol 125. issue 1-2. 2002-05-31. PMID:11960647. |
during the demyelinating phase of chronic relapsing eae in abh mice, anti-myelin oligodendrocyte glycoprotein (mog) responses were increased compared to the inflammatory acute phase, but such levels did not correlate with the severity of clinical disease. |
2002-05-31 |
2023-08-12 |
mouse |
| Stephen Mark Tompkins, Josette Padilla, Mauro C Dal Canto, Jenny P-Y Ting, Luc Van Kaer, Stephen D Mille. De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 168. issue 8. 2002-05-23. PMID:11937578. |
c57bl/6 (b6) mice deficient for the class ii transactivator, which have defects in mhc class ii, invariant chain (ii), and h-2m (dm) expression, are resistant to initiation of myelin oligodendrocyte protein (mog) peptide, mog(35-55)-specific eae by both priming and adoptive transfer of encephalitogenic t cells. |
2002-05-23 |
2023-08-12 |
mouse |
| Rachael Reiman, Craig Gerard, Iain L Campbell, Scott R Barnu. Disruption of the C5a receptor gene fails to protect against experimental allergic encephalomyelitis. European journal of immunology. vol 32. issue 4. 2002-05-20. PMID:11932923. |
to investigate the role of the c5ar in this t cell-driven autoimmune model, we induced eae in c5ar-deficient mice (c5ar(-/-)) and wild-type mice using a myelin oligodendrocyte glycoprotein (mog) peptide as the immunogen. |
2002-05-20 |
2023-08-12 |
mouse |
| Michael F Mesleh, Nicole Belmar, Chuan Wei Lu, V V Krishnan, Robert S Maxwell, Claude P Genain, Monique Cosma. Marmoset fine B cell and T cell epitope specificities mapped onto a homology model of the extracellular domain of human myelin oligodendrocyte glycoprotein. Neurobiology of disease. vol 9. issue 2. 2002-05-09. PMID:11895369. |
aberrant association of autoantibodies with myelin oligodendrocyte glycoprotein (mog), an integral membrane protein of the central nervous system (cns) myelin, has been implicated in the pathogenesis of multiple sclerosis (ms). |
2002-05-09 |
2023-08-12 |
human |
| R Egg, M Reindl, F Deisenhammer, C Linington, T Berge. Anti-MOG and anti-MBP antibody subclasses in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). vol 7. issue 5. 2002-05-01. PMID:11724443. |
in this study we investigated igm, iga and igg serum antibodies against the myelin oligodendrocyte glycoprotein (mog) and the myelin basic protein (mbp) in 261 ms patients. |
2002-05-01 |
2023-08-12 |
Not clear |
| Caigan Du, Subramaniam Srira. Increased severity of experimental allergic encephalomyelitis in lyn-/- mice in the absence of elevated proinflammatory cytokine response in the central nervous system. Journal of immunology (Baltimore, Md. : 1950). vol 168. issue 6. 2002-04-15. PMID:11884485. |
following immunization with myelin oligodendrocyte protein (mog) p35-55, lyn(-/-) mice had higher clinical and pathological severity scores of eae when compared with wild type (wt). |
2002-04-15 |
2023-08-12 |
mouse |
| N H R Hamilton, J L Banyer, A J Hapel, S Mahalingam, A J Ramsay, I A Ramshaw, S A Thomso. IFN-gamma regulates murine interferon-inducible T cell alpha chemokine (I-TAC) expression in dendritic cell lines and during experimental autoimmune encephalomyelitis (EAE). Scandinavian journal of immunology. vol 55. issue 2. 2002-04-11. PMID:11896933. |
because i-tac appears to be secreted from antigen-presenting cells (apcs) and attracts activated t cells, we examined the level of murine i-tac mrna in the central nervous system (cns) of wild-type and ifn-gamma-receptor knockout (ifn-gammar-/-) mice with myelin oligodendrocyte glycoprotein (mog)35-55 peptide-induced experimental autoimmune encephalomyelitis (eae). |
2002-04-11 |
2023-08-12 |
mouse |
| K-B Abdul-Majid, A Stefferl, C Bourquin, H Lassmann, C Linington, T Olsson, S Kleinau, R A Harri. Fc receptors are critical for autoimmune inflammatory damage to the central nervous system in experimental autoimmune encephalomyelitis. Scandinavian journal of immunology. vol 55. issue 1. 2002-03-06. PMID:11841694. |
we investigated the role of fc receptors (fcrs), which link the cellular and humoral branches of the immune system, in myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae), using two different fcrgamma knockout dba/1 mice. |
2002-03-06 |
2023-08-12 |
mouse |
| Jan Bauer, Monika Bradl, Matthias Klein, Marianne Leisser, Thomas L Deckwerth, Hartmut Wekerle, Hans Lassman. Endoplasmic reticulum stress in PLP-overexpressing transgenic rats: gray matter oligodendrocytes are more vulnerable than white matter oligodendrocytes. Journal of neuropathology and experimental neurology. vol 61. issue 1. 2002-02-26. PMID:11829340. |
here we show that in rats that overexpress plp, impairment of plp transport from the cell body to the processes interferes with the translocation of other membrane proteins such as myelin-associated glycoprotein (mag) and myelin oligodendrocyte glycoprotein (mog), but not with peripherally translated mbp. |
2002-02-26 |
2023-08-12 |
rat |
| M Yura, I Takahashi, S Terawaki, T Hiroi, M N Kweon, Y Yuki, H Kiyon. Nasal administration of cholera toxin (CT) suppresses clinical signs of experimental autoimmune encephalomyelitis (EAE). Vaccine. vol 20. issue 1-2. 2002-01-29. PMID:11567757. |
we induced eae in c57bl/6 mice with myelin oligodendrocyte glycoprotein (mog) 35-55 and ct was nasally administered as an immunomodulator on day 7 following mog challenge. |
2002-01-29 |
2023-08-12 |
mouse |
| M Minohara, H Ochi, S Matsushita, A Irie, Y Nishimura, J Kir. Differences between T-cell reactivities to major myelin protein-derived peptides in opticospinal and conventional forms of multiple sclerosis and healthy controls. Tissue antigens. vol 57. issue 5. 2002-01-17. PMID:11556969. |
to clarify the characteristics of t cells autoreactive to myelin proteins in each ms subtype, we established t-cell lines reactive to such myelin antigens as myelin basic protein (mbp), proteolipid protein (plp) and myelin oligodendrocyte glycoprotein (mog) from 5 of 10 os-ms patients, 6 of 11 c-ms patients and 7 of 13 healthy controls (hcs), and t-cell epitopes and their restriction molecules were determined. |
2002-01-17 |
2023-08-12 |
Not clear |
| R D McShane, D S Gallagher, H Newkirk, J F Taylor, J D Burzlaff, S K Davis, L C Sko. Physical localization and order of genes in the class I region of the bovine MHC. Animal genetics. vol 32. issue 5. 2002-01-17. PMID:11683708. |
myelin oligodendrocyte glycoprotein (mog) was shown to be imbedded within the bola class i gene cluster. |
2002-01-17 |
2023-08-12 |
cattle |
| A Iglesias, J Bauer, T Litzenburger, A Schubart, C Liningto. T- and B-cell responses to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis and multiple sclerosis. Glia. vol 36. issue 2. 2002-01-04. PMID:11596130. |
the identification of myelin oligodendrocyte glycoprotein (mog) as a target for autoantibody-mediated demyelination in experimental autoimmune encephalomyelitis (eae) resulted in the re-evaluation of the role of b cell responses to myelin autoantigens in the immunopathogenesis of multiple sclerosis. |
2002-01-04 |
2023-08-12 |
mouse |
| T G Forsthuber, C L Shive, W Wienhold, K de Graaf, E G Spack, R Sublett, A Melms, J Kort, M K Racke, R Weisser. T cell epitopes of human myelin oligodendrocyte glycoprotein identified in HLA-DR4 (DRB1*0401) transgenic mice are encephalitogenic and are presented by human B cells. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 12. 2001-12-27. PMID:11739534. |
myelin oligodendrocyte glycoprotein (mog) is an ag present in the myelin sheath of the cns thought to be targeted by the autoimmune t cell response in multiple sclerosis (ms). |
2001-12-27 |
2023-08-12 |
mouse |
| R Gregersen, T Christensen, E Lehrmann, N H Diemer, B Finse. Focal cerebral ischemia induces increased myelin basic protein and growth-associated protein-43 gene transcription in peri-infarct areas in the rat brain. Experimental brain research. vol 138. issue 3. 2001-12-07. PMID:11460777. |
within the infarct, mbp messenger rna (mrna) had disappeared by 24 h, whereas myelin protein, identified by mbp and myelin oligodendrocyte glycoprotein (mog) immunohistochemistry, appeared structurally intact until day 3. |
2001-12-07 |
2023-08-12 |
rat |