Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Meenakshi Khare, Moses Rodriguez, Chella S Davi. HLA class II transgenic mice authenticate restriction of myelin oligodendrocyte glycoprotein-specific immune response implicated in multiple sclerosis pathogenesis. International immunology. vol 15. issue 4. 2003-12-18. PMID:12663683. |
myelin oligodendrocyte glycoprotein (mog) is a potential target antigen of the central nervous system (cns), known to induce autoreactive t cell response and demyelinating anti-mog antibodies in multiple sclerosis (ms) patients. |
2003-12-18 |
2023-08-12 |
mouse |
Yossi Gilgun-Sherki, Hana Panet, Vered Holdengreber, Ronit Mosberg-Galili, Daniel Offe. Axonal damage is reduced following glatiramer acetate treatment in C57/bl mice with chronic-induced experimental autoimmune encephalomyelitis. Neuroscience research. vol 47. issue 2. 2003-12-11. PMID:14512144. |
here we report that ga reduced the clinical and pathological signs of mice in chronic eae induced by myelin oligodendrocyte glycoprotein (mog). |
2003-12-11 |
2023-08-12 |
mouse |
Hideto Ikushima, Masaharu Kanaoka, Shinichi Kojim. Cutting edge: Requirement for growth hormone-releasing hormone in the development of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 6. 2003-12-04. PMID:12960295. |
we found that lit/lit mice were resistant to myelin oligodendrocyte glycoprotein (mog)-induced eae. |
2003-12-04 |
2023-08-12 |
mouse |
Khairul Bariah Abdul-Majid, Judit Wefer, Christine Stadelmann, Andreas Stefferl, Hans Lassmann, Tomas Olsson, Robert A Harri. Comparing the pathogenesis of experimental autoimmune encephalomyelitis in CD4-/- and CD8-/- DBA/1 mice defines qualitative roles of different T cell subsets. Journal of neuroimmunology. vol 141. issue 1-2. 2003-12-04. PMID:12965249. |
experimental autoimmune encephalomyelitis (eae) was induced with myelin oligodendrocyte glycoprotein (mog(1-125)) in cd4(-/-) and cd8(-/-) dba/1 mice. |
2003-12-04 |
2023-08-12 |
mouse |
Maria Pagany, Maja Jagodic, Anna Schubart, Danielle Pham-Dinh, Corinne Bachelin, Anne Baron van Evercooren, François Lachapelle, Tomas Olsson, Christopher Liningto. Myelin oligodendrocyte glycoprotein is expressed in the peripheral nervous system of rodents and primates. Neuroscience letters. vol 350. issue 3. 2003-11-10. PMID:14550920. |
the myelin oligodendrocyte glycoprotein (mog) is a minor cns myelin-specific protein that is an important candidate autoantigen in multiple sclerosis. |
2003-11-10 |
2023-08-12 |
Not clear |
Mandy L Ford, Brian D Evavol. Regulation of polyclonal T cell responses by an MHC anchor-substituted variant of myelin oligodendrocyte glycoprotein 35-55. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 3. 2003-11-07. PMID:12874212. |
in this study, we demonstrate that individual myelin oligodendrocyte glycoprotein (mog) 35-55-specific t cell clones responded differentially to a mog 35-55 apl, raising questions about the ability of peptide analogs containing amino acid substitutions at tcr contact residues to control polyclonal populations of t cells. |
2003-11-07 |
2023-08-12 |
Not clear |
Craig S Clements, Hugh H Reid, Travis Beddoe, Fleur E Tynan, Matthew A Perugini, Terrance G Johns, Claude C A Bernard, Jamie Rossjoh. The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 19. 2003-10-29. PMID:12960396. |
myelin oligodendrocyte glycoprotein (mog) is a key cns-specific autoantigen for primary demyelination in multiple sclerosis. |
2003-10-29 |
2023-08-12 |
Not clear |
Michael Schroeter, Guido Stoll, Robert Weissert, Hans-Peter Hartung, Hans Lassmann, Sebastian Jande. CD8+ phagocyte recruitment in rat experimental autoimmune encephalomyelitis: association with inflammatory tissue destruction. The American journal of pathology. vol 163. issue 4. 2003-10-29. PMID:14507658. |
unexpectedly, in chronic demyelinating eae induced by immunization against myelin oligodendrocyte glycoprotein (mog) the majority of cd8 immunoreactivity was expressed on ed1(+) microglia/macrophages whereas only limited cd8(+) t-cell infiltration was present. |
2003-10-29 |
2023-08-12 |
rat |
Odile Costa, Didier Divoux, Alexander Ischenko, François Tron, Marc Fontain. Optimization of an animal model of experimental autoimmune encephalomyelitis achieved with a multiple MOG(35-55)peptide in C57BL6/J strain of mice. Journal of autoimmunity. vol 20. issue 1. 2003-10-16. PMID:12604312. |
to determine whether the immunization protocol could have an influence on clinical signs, c57bl6/j mice were immunized with a multiple antigen peptide (map) containing eight pmog(35-55)branches synthesized directly onto a lysine core, myelin oligodendrocyte glycoprotein (35-55)-multiple antigen peptide (mog(35-55)-map), in complete freund's adjuvant (cfa). |
2003-10-16 |
2023-08-12 |
mouse |
Constanze Breithaupt, Anna Schubart, Hilke Zander, Arne Skerra, Robert Huber, Christopher Linington, Uwe Jaco. Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 16. 2003-10-03. PMID:12874380. |
the immunopathogenesis of demyelination in multiple sclerosis involves an autoantibody response to myelin oligodendrocyte glycoprotein (mog), a type i transmembrane protein located at the surface of cns myelin. |
2003-10-03 |
2023-08-12 |
Not clear |
Alan D Salama, Tanuja Chitnis, Jaime Imitola, Mohammed Javeed I Ansari, Hisaya Akiba, Fumihiko Tushima, Miyuki Azuma, Hideo Yagita, Mohamed H Sayegh, Samia J Khour. Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. The Journal of experimental medicine. vol 198. issue 1. 2003-10-02. PMID:12847138. |
after immunization with myelin oligodendrocyte glycoprotein (mog) there was a progressive increase in expression of pd-1 and its ligand pd-l1 but not pd-l2 within the central nervous system (cns) of mice with eae, peaking after 3 wk. |
2003-10-02 |
2023-08-12 |
mouse |
Anne Camille La Flamme, Kate Ruddenklau, B Thomas Bäckströ. Schistosomiasis decreases central nervous system inflammation and alters the progression of experimental autoimmune encephalomyelitis. Infection and immunity. vol 71. issue 9. 2003-09-29. PMID:12933842. |
a preestablished infection with the parasitic helminth, schistosoma mansoni, significantly reduced the incidence and delayed the onset of experimental autoimmune encephalomyelitis (eae) in c57bl/6j mice immunized with myelin oligodendrocyte glycoprotein (mog)(35-55) peptide. |
2003-09-29 |
2023-08-12 |
mouse |
Ewa Balkowiec-Iskra, Iwona Kurkowska-Jastrzebska, Ilona Joniec, Anna Czlonkowska, Andrzej Czlonkowsk. Post intoxicative therapeutic immunization with myelin oligodendrocyte glycoproteine (MOG 35-55) suppresses spontaneous regeneration of dopaminergic neurons injured with 1-methyl-4 phenyl-1,2,3,6-tetrahydropiridine (MPTP). Acta neurobiologiae experimentalis. vol 63. issue 2. 2003-09-26. PMID:12926537. |
post intoxicative therapeutic immunization with myelin oligodendrocyte glycoproteine (mog 35-55) suppresses spontaneous regeneration of dopaminergic neurons injured with 1-methyl-4 phenyl-1,2,3,6-tetrahydropiridine (mptp). |
2003-09-26 |
2023-08-12 |
mouse |
Arthur A Vandenbark, Cathleen Rich, Jeff Mooney, Alex Zamora, Chunhe Wang, Jianya Huan, Lars Fugger, Halina Offner, Richard Jones, Gregory G Burrow. Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 1. 2003-09-22. PMID:12816990. |
in a previous study, we demonstrated that myelin oligodendrocyte glycoprotein (mog)-35-55 peptide could induce severe chronic experimental autoimmune encephalomyelitis (eae) in hla-dr2(+) transgenic mice lacking all mouse mhc class ii genes. |
2003-09-22 |
2023-08-12 |
mouse |
Carole Bourquin, Anna Schubart, Stephanie Tobollik, Ian Mather, Sherry Ogg, Roland Liblau, Christopher Liningto. Selective unresponsiveness to conformational B cell epitopes of the myelin oligodendrocyte glycoprotein in H-2b mice. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 1. 2003-09-22. PMID:12817030. |
autoantibodies directed against conformation-dependent epitopes of the extracellular domain of the myelin oligodendrocyte glycoprotein (mog(igd)) play a major role in the immunopathogenesis of demyelination in experimental autoimmune encephalomyelitis. |
2003-09-22 |
2023-08-12 |
mouse |
Alfred R Oliver, Geoffrey M Lyon, Nancy H Ruddl. Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 mice. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 1. 2003-09-22. PMID:12817031. |
c57bl/6 mice immunized with the extracellular ig-like domain of rat myelin oligodendrocyte glycoprotein (mog) developed experimental autoimmune encephalomyelitis (eae) resembling that induced by rodent mog 35-55 in its b cell independence and predominantly mononuclear cns infiltrate. |
2003-09-22 |
2023-08-12 |
mouse |
Ricarda Diem, Muriel Hobom, Katharina Maier, Robert Weissert, Maria K Storch, Roman Meyer, Mathias Bäh. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 18. 2003-09-09. PMID:12904460. |
the rationale for corticosteroid treatment lies in the antiinflammatory and immunosuppressive properties of these drugs, as shown in experimental autoimmune encephalomyelitis (eae), the animal model of ms. to investigate the influence of methylprednisolone therapy on the survival of retinal ganglion cells (rgcs), the neurons that form the axons of the on, we used a rat model of myelin oligodendrocyte glycoprotein (mog)-induced eae. |
2003-09-09 |
2023-08-12 |
rat |
Roberto Furlan, Alessandra Bergami, Daniela Cantarella, Elena Brambilla, Masaro Taniguchi, Paolo Dellabona, Giulia Casorati, Gianvito Martin. Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma. European journal of immunology. vol 33. issue 7. 2003-08-27. PMID:12811843. |
nkt cells protects from experimental autoimmune encephalomyelitis (eae), an immune-mediated disease of the central nervous system mimicking multiple sclerosis, induced in c57bl/6 mice by the myelin oligodendrocyte glycoprotein (mog) encephalitogenic peptide aa 35-55. alphagalcer was administered at the time of immunization s.c., mixed with complete freund's adjuvant and mog35-55 peptide, or administered i.p., diluted in pbs. |
2003-08-27 |
2023-08-12 |
mouse |
Kristina Becanovic, Liselotte Bäckdahl, Erik Wallström, Fahmy Aboul-Enein, Hans Lassmann, Tomas Olsson, Johnny C Lorentze. Paradoxical effects of arthritis-regulating chromosome 4 regions on myelin oligodendrocyte glycoprotein-induced encephalomyelitis in congenic rats. European journal of immunology. vol 33. issue 7. 2003-08-27. PMID:12811851. |
we here studied myelin oligodendrocyte glycoprotein (mog)-induced eae in rat strains congenic for arthritis-regulating genome regions on chromosome 4. |
2003-08-27 |
2023-08-12 |
rat |
C B Marta, C M Taylor, T Coetzee, T Kim, S Winkler, R Bansal, S E Pfeiffe. Antibody cross-linking of myelin oligodendrocyte glycoprotein leads to its rapid repartitioning into detergent-insoluble fractions, and altered protein phosphorylation and cell morphology. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 13. 2003-08-14. PMID:12843245. |
myelin oligodendrocyte glycoprotein (mog) is, quantitatively, a relatively minor component of the myelin membrane. |
2003-08-14 |
2023-08-12 |
Not clear |