Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Itzhak Mendel, Kannan Natarajan, Avraham Ben-Nun, Ethan M Shevac. A novel protective model against experimental allergic encephalomyelitis in mice expressing a transgenic TCR-specific for myelin oligodendrocyte glycoprotein. Journal of neuroimmunology. vol 149. issue 1-2. 2004-05-10. PMID:15020060. |
myelin oligodendrocyte glycoprotein (mog) is an important autoantigen in multiple sclerosis and in experimental autoimmune encephalomyelitis (eae). |
2004-05-10 |
2023-08-12 |
mouse |
Guang-Xian Zhang, Shuo Yu, Bruno Gran, Jifen Li, Divina Calida, Elvira Ventura, Xiaohan Chen, Abdolmohamad Rostam. T cell and antibody responses in remitting-relapsing experimental autoimmune encephalomyelitis in (C57BL/6 x SJL) F1 mice. Journal of neuroimmunology. vol 148. issue 1-2. 2004-04-05. PMID:14975581. |
to characterize t cell and antibody responses in remitting-relapsing experimental autoimmune encephalomyelitis (rr-eae), we compared myelin oligodendrocyte glycoprotein (mog)-induced rr-eae in c57bl/6 (b6) x sjl (f1) mice and chronic-progressive eae (cp-eae) in b6 mice at week 8 p.i. |
2004-04-05 |
2023-08-12 |
mouse |
Robyn S Klein, Leonid Izikson, Terry Means, Hilary D Gibson, Eugene Lin, Raymond A Sobel, Howard L Weiner, Andrew D Luste. IFN-inducible protein 10/CXC chemokine ligand 10-independent induction of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 172. issue 1. 2004-04-02. PMID:14688366. |
in the present study, we report that targeted deletion of ip-10 did not diminish the expression, severity, or histopathology of eae induced by active immunization with 100 micro g of myelin oligodendrocyte glycoprotein peptide (mog)p35-55. |
2004-04-02 |
2023-08-12 |
mouse |
Johannes Guggenmos, Anna S Schubart, Sherry Ogg, Magnus Andersson, Tomas Olsson, Ian H Mather, Christopher Liningto. Antibody cross-reactivity between myelin oligodendrocyte glycoprotein and the milk protein butyrophilin in multiple sclerosis. Journal of immunology (Baltimore, Md. : 1950). vol 172. issue 1. 2004-04-02. PMID:14688379. |
in this study, we demonstrate that ab specific for the extracellular ig-like domain of myelin oligodendrocyte glycoprotein (mog) cross-reacts with a homologous n-terminal domain of the bovine milk protein butyrophilin (btn). |
2004-04-02 |
2023-08-12 |
cattle |
Mandy L Ford, Brian D Evavol. An MHC anchor-substituted analog of myelin oligodendrocyte glycoprotein 35-55 induces IFN-gamma and autoantibodies in the absence of experimental autoimmune encephalomyelitis and optic neuritis. European journal of immunology. vol 34. issue 2. 2004-03-30. PMID:14768043. |
we recently showed that a variant of myelin oligodendrocyte glycoprotein (mog) 35-55 possessing low affinity for mhc (45d) induced anergy in mog 35-55-specific t cells and reduced their encephalitogenicity upon adoptive transfer. |
2004-03-30 |
2023-08-12 |
mouse |
Susanna Carboni, Fahmy Aboul-Enein, Caroline Waltzinger, Nigel Killeen, Hans Lassmann, Claudia Peña-Ross. CD134 plays a crucial role in the pathogenesis of EAE and is upregulated in the CNS of patients with multiple sclerosis. Journal of neuroimmunology. vol 145. issue 1-2. 2004-03-22. PMID:14644025. |
eae induced by myelin oligodendrocyte glycoprotein (mog) injection in cd134(-/-) mice showed less severe clinical signs of disease and markedly reduced inflammatory infiltrates within the central nervous system (cns). |
2004-03-22 |
2023-08-12 |
mouse |
Troels R Petersen, Estelle Bettelli, John Sidney, Alessandro Sette, Vijay Kuchroo, B Thomas Bäckströ. Characterization of MHC- and TCR-binding residues of the myelin oligodendrocyte glycoprotein 38-51 peptide. European journal of immunology. vol 34. issue 1. 2004-03-16. PMID:14971042. |
myelin oligodendrocyte glycoprotein (mog) is a major experimental autoimmune encephalomyelitis (eae) antigen in h-2b mice and a potential autoantigen in multiple sclerosis. |
2004-03-16 |
2023-08-12 |
mouse |
Mandy L Ford, Thandi M Onami, Anne I Sperling, Rafi Ahmed, Brian D Evavol. CD43 modulates severity and onset of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 12. 2004-03-15. PMID:14662853. |
the absence of cd43 also affected cytokine production, as myelin oligodendrocyte glycoprotein (mog) 35-55-specific cd43(-/-) cd4(+) t cells exhibited reduced ifn-gamma and increased il-4 production. |
2004-03-15 |
2023-08-12 |
mouse |
Dan Frenkel, Zhihong Huang, Ruth Maron, Djordje N Koldzic, Wayne W Hancock, Michael A Moskowitz, Howard L Weine. Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 12. 2004-03-15. PMID:14662856. |
we mucosally administered myelin oligodendrocyte glycoprotein (mog) 35-55 peptide to c57bl/6 mice before middle cerebral artery occlusion (mcao) to induce an anti-inflammatory t cell response directed at cns myelin. |
2004-03-15 |
2023-08-12 |
mouse |
Marcel Zocher, Patrick A Baeuerle, Torsten Dreier, Antonio Iglesia. Specific depletion of autoreactive B lymphocytes by a recombinant fusion protein in vitro and in vivo. International immunology. vol 15. issue 7. 2004-03-08. PMID:12807817. |
we have designed and expressed a fusion protein, referred to as mog-fc, composed of the extracellular ig-like domain of human myelin oligodendrocyte glycoprotein (mog) and the c(h)2 and c(h)3 domains of the human igg1 heavy chain. |
2004-03-08 |
2023-08-12 |
mouse |
L E Hughes, P A Smith, S Bonell, R S Natt, C Wilson, T Rashid, S Amor, E J Thompson, J Croker, A Ebringe. Cross-reactivity between related sequences found in Acinetobacter sp., Pseudomonas aeruginosa, myelin basic protein and myelin oligodendrocyte glycoprotein in multiple sclerosis. Journal of neuroimmunology. vol 144. issue 1-2. 2004-03-02. PMID:14597104. |
antibodies to mimicry peptides from acinetobacter (p<0.001), p. aeruginosa (p<0.001), myelin basic protein (mbp) (p<0.001) and myelin oligodendrocyte glycoprotein (mog) (p<0.001) were significantly elevated in ms patients compared to controls. |
2004-03-02 |
2023-08-12 |
Not clear |
Chandramohan Natarajan, Gladson Muthian, Yaavov Barak, Ronald M Evans, John J Brigh. Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 11. 2004-03-01. PMID:14634082. |
in this study, we show that the ppargamma-deficient heterozygous mice develop an exacerbated eae with prolonged clinical symptoms than the wild-type littermates, following immunization with myelin oligodendrocyte glycoprotein (mog) p35-55 peptide. |
2004-03-01 |
2023-08-12 |
mouse |
Akio Suzumura, Atsushi Ito, Tetsuya Mizun. Phosphodiesterase inhibitors suppress IL-12 production with microglia and T helper 1 development. Multiple sclerosis (Houndmills, Basingstoke, England). vol 9. issue 6. 2004-02-26. PMID:14664469. |
in addition, the pdei ibudilast also suppressed interferon-gamma, but not il-4 or il-10, production by myelin oligodendrocyte glycoprotein (mog)-specific t cells reactivated with mog in the presence of microglia. |
2004-02-26 |
2023-08-12 |
Not clear |
Richard Reynolds, Mary Dawson, Dimitrios Papadopoulos, Annabella Polito, Isabelle Cenci Di Bello, Danielle Pham-Dinh, Joel Levin. The response of NG2-expressing oligodendrocyte progenitors to demyelination in MOG-EAE and MS. Journal of neurocytology. vol 31. issue 6-7. 2004-02-11. PMID:14501221. |
here we review the literature on the response of ng2-expressing opcs to demyelination and provide some new evidence on their response to the chronic inflammatory demyelinating environment seen in recombinant myelin oligodendrocyte glycoprotein (mog) induced experimental allergic encephalomyelitis (eae) in the da rat. |
2004-02-11 |
2023-08-12 |
human |
Robert D Hollifield, Laurence S Harbige, Danielle Pham-Dinh, Mohammed K Sharie. Evidence for cytokine dysregulation in multiple sclerosis: peripheral blood mononuclear cell production of pro-inflammatory and anti-inflammatory cytokines during relapse and remission. Autoimmunity. vol 36. issue 3. 2004-01-30. PMID:12911279. |
we investigated circulating anti-inflammatory and pro-inflammatory cytokines, and their ex vivo pbmc production in the absence or presence of the neuroantigens myelin basic protein (mbp) and myelin oligodendrocyte glycoprotein (mog) and t cell mitogen (pha) in ms patients in relapse and remission, patients with other neurological disorders (ond) and normal healthy controls. |
2004-01-30 |
2023-08-12 |
Not clear |
Guang-Xian Zhang, Shuo Yu, Bruno Gran, Jifen Li, Ines Siglienti, Xiaohan Chen, Divina Calida, Elvira Ventura, Malek Kamoun, Abdolmohamad Rostam. Role of IL-12 receptor beta 1 in regulation of T cell response by APC in experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 9. 2004-01-30. PMID:14568921. |
il-12rbeta1(-/-) mice are completely resistant to myelin oligodendrocyte glycoprotein (mog)-induced eae, with an autoantigen-specific th2 response. |
2004-01-30 |
2023-08-12 |
mouse |
Yossi Gilgun-Sherki, Hana Panet, Eldad Melamed, Daniel Offe. Riluzole suppresses experimental autoimmune encephalomyelitis: implications for the treatment of multiple sclerosis. Brain research. vol 989. issue 2. 2004-01-28. PMID:14556941. |
therefore, we examined whether riluzole, an inhibitor of glutamate transmission, affects the pathogenesis and clinical features of ms-like disease in myelin oligodendrocyte glycoprotein (mog)-induced eae in mice. |
2004-01-28 |
2023-08-12 |
mouse |
Hanna Cwiklinska, Marcin P Mycko, Otgonbajar Luvsannorov, Bogdan Walkowiak, Celia F Brosnan, Cedric S Raine, Krzysztof W Selma. Heat shock protein 70 associations with myelin basic protein and proteolipid protein in multiple sclerosis brains. International immunology. vol 15. issue 2. 2004-01-06. PMID:12578854. |
we have investigated the association of hsp70 with myelin basic protein (mbp), myelin proteolipid protein (plp) and myelin oligodendrocyte protein (mog) in ms and control brain tissue. |
2004-01-06 |
2023-08-12 |
mouse |
Deming Sun, Yiping Zhang, Bingyuan Wei, Stephen C Peiper, Hui Shao, Henry J Kapla. Encephalitogenic activity of truncated myelin oligodendrocyte glycoprotein (MOG) peptides and their recognition by CD8+ MOG-specific T cells on oligomeric MHC class I molecules. International immunology. vol 15. issue 2. 2004-01-06. PMID:12578856. |
encephalitogenic activity of truncated myelin oligodendrocyte glycoprotein (mog) peptides and their recognition by cd8+ mog-specific t cells on oligomeric mhc class i molecules. |
2004-01-06 |
2023-08-12 |
mouse |
Deming Sun, Yiping Zhang, Bingyuan Wei, Stephen C Peiper, Hui Shao, Henry J Kapla. Encephalitogenic activity of truncated myelin oligodendrocyte glycoprotein (MOG) peptides and their recognition by CD8+ MOG-specific T cells on oligomeric MHC class I molecules. International immunology. vol 15. issue 2. 2004-01-06. PMID:12578856. |
we have previously demonstrated that the 21-residue peptide pmog(35-55) from myelin oligodendrocyte glycoprotein (mog) contains an antigenic epitope that activates cd8(+) encephalitogenic t cells in c57bl/6 (b6) mice. |
2004-01-06 |
2023-08-12 |
mouse |