| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emily Mills Ko, Joyce H Ma, Fuzheng Guo, Laird Miers, Eunyoung Lee, Peter Bannerman, Travis Burns, David Ko, Jiho Sohn, Athena M Soulika, David Pleasur. Deletion of astroglial CXCL10 delays clinical onset but does not affect progressive axon loss in a murine autoimmune multiple sclerosis model. Journal of neuroinflammation. vol 11. 2014-12-01. PMID:24924222. |
these mice, and littermate controls, were immunized with myelin oligodendrocyte glycoprotein peptide 35-55 (mog peptide) to induce experimental autoimmune encephalomyelitis (eae). |
2014-12-01 |
2023-08-13 |
mouse |
| Xing-Mei Zhang, Harald Lund, Sohel Mia, Roham Parsa, Robert A Harri. Adoptive transfer of cytokine-induced immunomodulatory adult microglia attenuates experimental autoimmune encephalomyelitis in DBA/1 mice. Glia. vol 62. issue 5. 2014-11-24. PMID:24677019. |
myelin oligodendrocyte glycoprotein (mog)-induced eae was induced in dba/1 mice and at different time points (0, 5, 12, or 15 days postimmunization) 3 × 105 m2 microglia were transferred intranasally. |
2014-11-24 |
2023-08-12 |
mouse |
| Kerstin Göbel, Michael K Schuhmann, Susann Pankratz, David Stegner, Alexander M Herrmann, Attila Braun, Johanna Breuer, Stefan Bittner, Tobias Ruck, Heinz Wiendl, Christoph Kleinschnitz, Bernhard Nieswandt, Sven G Meut. Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis. European journal of immunology. vol 44. issue 8. 2014-11-18. PMID:24811005. |
by using pld1-deficient mice, we investigated the functional significance of pld1 for lymphocyte adhesion and migration in vitro and after myelin oligodendrocyte glycoprotein (mog)35-55 -induced eae, a model of human ms. |
2014-11-18 |
2023-08-13 |
mouse |
| Liliana E Lucca, Sabine Desbois, Abdulraouf Ramadan, Avraham Ben-Nun, Miriam Eisenstein, Nadège Carrié, Jean-Charles Guéry, Alessandro Sette, Phuong Nguyen, Terrence L Geiger, Lennart T Mars, Roland S Libla. Bispecificity for myelin and neuronal self-antigens is a common feature of CD4 T cells in C57BL/6 mice. Journal of immunology (Baltimore, Md. : 1950). vol 193. issue 7. 2014-11-14. PMID:25135834. |
we have previously shown that the 2d2 tcr recognizes the myelin oligodendrocyte glycoprotein epitope (mog)35-55 as well as an epitope within the axonal protein neurofilament medium (nf-m15-35) in h-2(b) mice. |
2014-11-14 |
2023-08-13 |
mouse |
| Yu-Han Liu, James Chan, Vijesh Vaghjiani, Padma Murthi, Ursula Manuelpillai, Ban-Hock To. Human amniotic epithelial cells suppress relapse of corticosteroid-remitted experimental autoimmune disease. Cytotherapy. vol 16. issue 4. 2014-11-10. PMID:24411589. |
previously we reported that haec given near disease onset ameliorated clinical signs and decreased myelin oligodendrocyte glycoprotein (mog)-specific immune responses in mog-induced experimental autoimmune encephalomyelitis (eae), an experimental ms model. |
2014-11-10 |
2023-08-12 |
human |
| Nilufer Esen, Zakhar Serkin, Paula Dore-Duff. Induction of vascular remodeling: a novel therapeutic approach in EAE. Journal of the neurological sciences. vol 333. issue 1-2. 2014-11-06. PMID:23810780. |
we therefore hypothesized that restoration of microvascular angiodynamics would augment tissue plasticity mitigating the extent of secondary injury and sparing cognitive decline in patients with ms. to test this hypothesis, we have performed preclinical studies and characterized changes in angiodynamics in myelin oligodendrocyte glycoprotein (mog) peptide (35-55)-induced eae in c57bl/6 mice with or without concomitant exposure to chronic mild low oxygen. |
2014-11-06 |
2023-08-12 |
mouse |
| Sudarshini Ramanathan, Stephen W Reddel, Andrew Henderson, John D E Parratt, Michael Barnett, Prudence N Gatt, Vera Merheb, Raani-Yogeeta Anusuiya Kumaran, Karrnan Pathmanandavel, Nese Sinmaz, Mahtab Ghadiri, Con Yiannikas, Steve Vucic, Graeme Stewart, Andrew F Bleasel, David Booth, Victor S C Fung, Russell C Dale, Fabienne Brilo. Antibodies to myelin oligodendrocyte glycoprotein in bilateral and recurrent optic neuritis. Neurology(R) neuroimmunology & neuroinflammation. vol 1. issue 4. 2014-11-03. PMID:25364774. |
we examined a cohort of adults with aquaporin-4 (aqp4) antibody-negative neuromyelitis optica/neuromyelitis optica spectrum disorder (nmo/nmosd) for antibodies to myelin oligodendrocyte glycoprotein (mog). |
2014-11-03 |
2023-08-13 |
Not clear |
| Yakov A Lomakin, Maria Yu Zakharova, Alexey V Stepanov, Maria A Dronina, Ivan V Smirnov, Tatyana V Bobik, Andrey Yu Pyrkov, Nina V Tikunova, Svetlana N Sharanova, Vitali M Boitsov, Sergey Yu Vyazmin, Marsel R Kabilov, Alexey E Tupikin, Alexey N Krasnov, Nadezda A Bykova, Yulia A Medvedeva, Marina V Fridman, Alexander V Favorov, Natalia A Ponomarenko, Michael V Dubina, Alexey N Boyko, Valentin V Vlassov, Alexey A Belogurov, Alexander G Gabibo. Heavy-light chain interrelations of MS-associated immunoglobulins probed by deep sequencing and rational variation. Molecular immunology. vol 62. issue 2. 2014-10-28. PMID:24534716. |
on the other hand, we have performed deep sequencing of the sublibraries of scfvs against mbp, epstein-barr virus (ebv) latent membrane protein 1 (lmp1), and myelin oligodendrocyte glycoprotein (mog). |
2014-10-28 |
2023-08-12 |
human |
| Russell C Dale, Esther M Tantsis, Vera Merheb, Raani-Yogeeta A Kumaran, Nese Sinmaz, Karrnan Pathmanandavel, Sudarshini Ramanathan, David R Booth, Louise A Wienholt, Kristina Prelog, Damien R Clark, Gilles J Guillemin, Chai K Lim, Emily K Mathey, Fabienne Brilo. Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton. Neurology(R) neuroimmunology & neuroinflammation. vol 1. issue 1. 2014-10-23. PMID:25340056. |
antibodies to mog have a demyelination phenotype and affect oligodendrocyte cytoskeleton. |
2014-10-23 |
2023-08-13 |
Not clear |
| Russell C Dale, Esther M Tantsis, Vera Merheb, Raani-Yogeeta A Kumaran, Nese Sinmaz, Karrnan Pathmanandavel, Sudarshini Ramanathan, David R Booth, Louise A Wienholt, Kristina Prelog, Damien R Clark, Gilles J Guillemin, Chai K Lim, Emily K Mathey, Fabienne Brilo. Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton. Neurology(R) neuroimmunology & neuroinflammation. vol 1. issue 1. 2014-10-23. PMID:25340056. |
to examine the clinical features of pediatric cns demyelination associated with positive myelin oligodendrocyte glycoprotein (mog) antibodies and to examine the functional effects of mog antibody on oligodendrocyte cytoskeleton. |
2014-10-23 |
2023-08-13 |
Not clear |
| Michel Varrin-Doyer, Aparna Shetty, Collin M Spencer, Ulf Schulze-Topphoff, Martin S Weber, Claude C A Bernard, Thomas Forsthuber, Bruce A C Cree, Anthony J Slavin, Scott S Zamvi. MOG transmembrane and cytoplasmic domains contain highly stimulatory T-cell epitopes in MS. Neurology(R) neuroimmunology & neuroinflammation. vol 1. issue 2. 2014-10-23. PMID:25340072. |
recently, we reported that the 218 amino acid murine full-length myelin oligodendrocyte glycoprotein (mog) contains novel t-cell epitopes p119-132, p181-195, and p186-200, located within its transmembrane and cytoplasmic domains, and that p119-132 is its immunodominant encephalitogenic t-cell epitope in mice. |
2014-10-23 |
2023-08-13 |
mouse |
| Aparna Shetty, Sheena G Gupta, Michel Varrin-Doyer, Martin S Weber, Thomas Prod'homme, Nicolas Molnarfi, Niannian Ji, Patricia A Nelson, Juan C Patarroyo, Ulf Schulze-Topphoff, Stephen E Fogal, Thomas Forsthuber, Raymond A Sobel, Claude C A Bernard, Anthony J Slavin, Scott S Zamvi. Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE. Neurology(R) neuroimmunology & neuroinflammation. vol 1. issue 2. 2014-10-23. PMID:25340074. |
studies evaluating t-cell recognition of myelin oligodendrocyte glycoprotein (mog) in multiple sclerosis (ms) and its model, experimental autoimmune encephalomyelitis (eae), have focused mostly on its 117 amino acid (aa) extracellular domain, especially peptide (p) 35-55. |
2014-10-23 |
2023-08-13 |
Not clear |
| Marjan Taherian, Ali Reza Razavi, Maryam Izad, Rubina Boghozian, Haydeh Namdari, Mojgan Ghayedi, Parisa Rahimzadeh, Katayoon Bidad, Eisa Saleh. The role of interleukin-23 in stability of in vitro T helper-17 cells. Iranian journal of allergy, asthma, and immunology. vol 13. issue 2. 2014-10-16. PMID:24338259. |
in this research project, we generated in vitro myelin oligodendrocyte glycoprotein (mog)-specific th17 cells in the presence of tgf-β, il-6, il-23 and peptide mog35-55. |
2014-10-16 |
2023-08-12 |
mouse |
| J J García-Vallejo, J M Ilarregui, H Kalay, S Chamorro, N Koning, W W Unger, M Ambrosini, V Montserrat, R J Fernandes, S C M Bruijns, J R T van Weering, N J Paauw, T O'Toole, J van Horssen, P van der Valk, K Nazmi, J G M Bolscher, J Bajramovic, C D Dijkstra, B A 't Hart, Y van Kooy. CNS myelin induces regulatory functions of DC-SIGN-expressing, antigen-presenting cells via cognate interaction with MOG. The Journal of experimental medicine. vol 211. issue 7. 2014-09-04. PMID:24935259. |
myelin oligodendrocyte glycoprotein (mog), a constituent of central nervous system myelin, is an important autoantigen in the neuroinflammatory disease multiple sclerosis (ms). |
2014-09-04 |
2023-08-13 |
human |
| Conan K Wang, Christian W Gruber, Maša Cemazar, Christopher Siatskas, Prascilla Tagore, Natalie Payne, Guizhi Sun, Shunhe Wang, Claude C Bernard, David J Crai. Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis. ACS chemical biology. vol 9. issue 1. 2014-09-02. PMID:24147816. |
peptide epitopes from cns proteins, such as myelin oligodendrocyte glycoprotein (mog), possess promising immunoregulatory potential for treating ms; however, their instability and poor bioavailability is a major impediment for their use clinically. |
2014-09-02 |
2023-08-12 |
mouse |
| De-Hyung Lee, Ralf A Linke. The role of myelin oligodendrocyte glycoprotein in autoimmune demyelination: a target for multiple sclerosis therapy? Expert opinion on therapeutic targets. vol 16. issue 5. 2014-08-29. PMID:22494461. |
myelin oligodendrocyte glycoprotein (mog) is a myelin antigen at the outer surface of the central nervous system (cns) myelin sheath, which may trigger t-cell as well as b-cell responses. |
2014-08-29 |
2023-08-12 |
Not clear |
| Thais Graziela Donegá França, Fernanda Chiuso-Minicucci, Sofia Fernanda Gonçalves Zorzella-Pezavento, Larissa Lumi Watanabe Ishikawa, Larissa Camargo da Rosa, Priscila Maria Colavite, Camila Marques, Maura Rosane Valério Ikoma, Maria de Lourdes Ribeiro de Souza da Cunha, Alexandrina Sartor. Previous infection with Staphylococcus aureus strains attenuated experimental encephalomyelitis. BMC neuroscience. vol 15. 2014-08-27. PMID:24401094. |
three days later, the animals were subjected to eae induction by immunization with myelin oligodendrocyte glycoprotein (mog). |
2014-08-27 |
2023-08-12 |
mouse |
| Jong-Hwan Lee, Hyuk Seong Seo, Jong Am Song, Koo Chul Kwon, Eun Jung Lee, Ho Jin Kim, Eun Bong Lee, Young Joo Cha, Jeewon Le. Proteinticle engineering for accurate 3D diagnosis. ACS nano. vol 7. issue 12. 2014-08-26. PMID:24195532. |
the surface display of the extracellular domain of myelin oligodendrocyte glycoprotein (mog) with native conformation successfully discriminated between autoantibodies to native or denatured mog, leading to the reliable diagnosis of multiple sclerosis with enhanced accuracy. |
2014-08-26 |
2023-08-12 |
human |
| Henrique Lemos, Lei Huang, Phillip R Chandler, Eslam Mohamed, Guilherme R Souza, Lingqian Li, Gabriela Pacholczyk, Glen N Barber, Yoshihiro Hayakawa, David H Munn, Andrew L Mello. Activation of the STING adaptor attenuates experimental autoimmune encephalitis. Journal of immunology (Baltimore, Md. : 1950). vol 192. issue 12. 2014-08-18. PMID:24799564. |
in this study, we show that systemic treatments with dna nanoparticles (dnps) induced potent immune regulatory responses via sting signaling that suppressed experimental autoimmune encephalitis (eae) when administered to mice after immunization with myelin oligodendrocyte glycoprotein (mog), at eae onset, or at peak disease severity. |
2014-08-18 |
2023-08-13 |
mouse |
| Xiaojie Wang, Joan K Brieland, Joong H Kim, Ying-Jr Chen, Janet O'Neal, Shawn P O'Neil, Tsang-Wei Tu, Kathryn Trinkaus, Sheng-Kwei Son. Diffusion tensor imaging detects treatment effects of FTY720 in experimental autoimmune encephalomyelitis mice. NMR in biomedicine. vol 26. issue 12. 2014-08-06. PMID:23939596. |
eae was induced through active immunization of c57bl/6 mice using myelin oligodendrocyte glycoprotein peptide 35-55 (mog(35-55)). |
2014-08-06 |
2023-08-12 |
mouse |