| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M José Mansilla, Carme Costa, Herena Eixarch, Vanja Tepavcevic, Mireia Castillo, Roland Martin, Catherine Lubetzki, Marie-Stéphane Aigrot, Xavier Montalban, Carmen Espej. Hsp70 regulates immune response in experimental autoimmune encephalomyelitis. PloS one. vol 9. issue 8. 2015-11-12. PMID:25153885. |
we found that hsp70.1-deficient mice were more resistant to developing experimental autoimmune encephalomyelitis (eae) compared with their wild-type (wt) littermates, suggesting that hsp70.1 plays a critical role in promoting an effective myelin oligodendrocyte glycoprotein (mog)-specific t cell response. |
2015-11-12 |
2023-08-13 |
mouse |
| Jyothi T Mony, Reza Khorooshi, Trevor Owen. MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE. Multiple sclerosis (Houndmills, Basingstoke, England). vol 20. issue 10. 2015-10-27. PMID:24552747. |
we asked whether immunization with the immunoglobulin-like domain of myelin oligodendrocyte glycoprotein (mog(igd), residues 1-125) might induce distinct cd4+ t-cell response and/or a stronger cd8+ t-cell response, compared to the 21 amino acid immunodominant mhc ii-associating peptide (p35-55). |
2015-10-27 |
2023-08-12 |
mouse |
| Theodore Tselios, Mihalis Aggelidakis, Anthi Tapeinou, Vivian Tseveleki, Ioannis Kanistras, Dimitrios Gatos, John Matsouka. Rational design and synthesis of altered peptide ligands based on human myelin oligodendrocyte glycoprotein 35-55 epitope: inhibition of chronic experimental autoimmune encephalomyelitis in mice. Molecules (Basel, Switzerland). vol 19. issue 11. 2015-10-14. PMID:25375337. |
although the etiology of ms remains unclear, there is evidence t-cell recognition of immunodominant epitopes of myelin proteins, such as the 35-55 epitope of myelin oligodendrocyte glycoprotein (mog), plays a pathogenic role in the induction of chronic eae. |
2015-10-14 |
2023-08-13 |
mouse |
| Joanna Jung, Elzbieta Dudek, Marek Michala. The role of N-glycan in folding, trafficking and pathogenicity of myelin oligodendrocyte glycoprotein (MOG). Biochimica et biophysica acta. vol 1853. issue 9. 2015-10-02. PMID:25541284. |
the role of n-glycan in folding, trafficking and pathogenicity of myelin oligodendrocyte glycoprotein (mog). |
2015-10-02 |
2023-08-13 |
Not clear |
| Joanna Jung, Elzbieta Dudek, Marek Michala. The role of N-glycan in folding, trafficking and pathogenicity of myelin oligodendrocyte glycoprotein (MOG). Biochimica et biophysica acta. vol 1853. issue 9. 2015-10-02. PMID:25541284. |
myelin oligodendrocyte glycoprotein (mog) is a type i integral membrane protein that is expressed in the central nervous system. |
2015-10-02 |
2023-08-13 |
Not clear |
| J Eckhardt, M Döbbeler, C König, K Kuczera, C Kuhnt, C Ostalecki, E Zinser, T W Mak, A Steinkasserer, M Lechman. Thymic stromal lymphopoietin deficiency attenuates experimental autoimmune encephalomyelitis. Clinical and experimental immunology. vol 181. issue 1. 2015-08-24. PMID:25753260. |
furthermore, cd3(+) t cells isolated in the preclinical phase from myelin oligodendrocyte glycoprotein peptide 35-55 (mog(35-55))-immunized tslp ko mice showed a reduced response after secondary exposure to mog(35-55), indicating that differentiation of naive t cells into mog(35-55)-specific effector and memory t cells was impaired in ko mice. |
2015-08-24 |
2023-08-13 |
mouse |
| Chelsea R Parker Harp, Angela S Archambault, Julia Sim, Stephen T Ferris, Robert J Mikesell, Pandelakis A Koni, Michiko Shimoda, Christopher Linington, John H Russell, Gregory F W. B cell antigen presentation is sufficient to drive neuroinflammation in an animal model of multiple sclerosis. Journal of immunology (Baltimore, Md. : 1950). vol 194. issue 11. 2015-08-17. PMID:25895531. |
in this study, we find that b cells cooperate with dendritic cells to enhance eae severity resulting from myelin oligodendrocyte glycoprotein (mog) immunization. |
2015-08-17 |
2023-08-13 |
mouse |
| S J Bing, D Ha, G Ahn, J Cho, A Kim, S K Park, H S Yu, Y Je. Galectin isolated from parasite inhibits remission of experimental autoimmune encephalomyelitis by up-regulating autoantibody. Clinical and experimental immunology. vol 180. issue 3. 2015-08-11. PMID:25619397. |
further, rtl-gal-treated eae mice markedly increased the number of cd45r/b220(+) b cells in both infiltrated inflammation and the periphery, along with the increased production of autoantibody [anti-myelin oligodendrocyte glycoprotein (mog)35-55 ] in serum at chronic stage. |
2015-08-11 |
2023-08-13 |
mouse |
| Davide Cossu, Giuseppe Mameli, Speranza Masala, Eleonora Cocco, Jessica Frau, Maria Giovanna Marrosu, Leonardo Antonio Sech. Evaluation of the humoral response against mycobacterial peptides, homologous to MOG₃₅₋₅₅, in multiple sclerosis patients. Journal of the neurological sciences. vol 347. issue 1-2. 2015-08-06. PMID:25271190. |
a peptide-based indirect elisa was used to detect antibodies against the encephalitogenic myelin oligodendrocyte glycoprotein (mog)35-55 epitope, and two mycobacterial peptides sharing sequence homology with the latter: map_2619c352-361/bcg_1224355-364 and bcg_3329c64-74. |
2015-08-06 |
2023-08-13 |
human |
| Rie S Tsuburaya, Naoki Miki, Keiko Tanaka, Takashi Kageyama, Kaori Irahara, Souichi Mukaida, Kazuhiro Shiraishi, Masami Tanak. Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in a Japanese boy with recurrent optic neuritis. Brain & development. vol 37. issue 1. 2015-08-04. PMID:24582475. |
anti-myelin oligodendrocyte glycoprotein (mog) antibodies in a japanese boy with recurrent optic neuritis. |
2015-08-04 |
2023-08-12 |
Not clear |
| Rie S Tsuburaya, Naoki Miki, Keiko Tanaka, Takashi Kageyama, Kaori Irahara, Souichi Mukaida, Kazuhiro Shiraishi, Masami Tanak. Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in a Japanese boy with recurrent optic neuritis. Brain & development. vol 37. issue 1. 2015-08-04. PMID:24582475. |
myelin oligodendrocyte glycoprotein (mog) localizes on the outermost surface of the myelin sheath and oligodendrocytes in the central nervous system (cns). |
2015-08-04 |
2023-08-12 |
Not clear |
| Christine Römer, Odilo Engel, Katarzyna Winek, Sonja Hochmeister, Tian Zhang, Georg Royl, Juliane Klehmet, Ulrich Dirnagl, Christian Meisel, Andreas Meise. Blocking stroke-induced immunodeficiency increases CNS antigen-specific autoreactivity but does not worsen functional outcome after experimental stroke. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 20. 2015-08-03. PMID:25995466. |
to address this, we used myelin oligodendrocyte glycoprotein (mog) t-cell receptor transgenic (2d2) mice where >80% of peripheral cd4(+) t cells express a functional receptor for mog. |
2015-08-03 |
2023-08-13 |
mouse |
| Shogo Tanabe, Toshihide Yamashit. Repulsive guidance molecule-a is involved in Th17-cell-induced neurodegeneration in autoimmune encephalomyelitis. Cell reports. vol 9. issue 4. 2015-07-21. PMID:25456136. |
we induced eae by adoptive transfer of myelin oligodendrocyte glycoprotein (mog)-specific th17 cells and then inhibited rgma with a neutralizing antibody. |
2015-07-21 |
2023-08-13 |
mouse |
| Tan Wang, Na-na Xi, Yu Chen, Xiao-feng Shang, Qiang Hu, Jiang-fan Chen, Rong-yuan Zhen. Chronic caffeine treatment protects against experimental autoimmune encephalomyelitis in mice: therapeutic window and receptor subtype mechanism. Neuropharmacology. vol 86. 2015-07-14. PMID:25019206. |
chronic treatment with caffeine, the most widely consumed psychoactive drug and a non-selective antagonist of adenosine receptors, can protection against myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae), an animal model of multiple sclerosis (ms). |
2015-07-14 |
2023-08-13 |
mouse |
| Stefan Bittner, Ali M Afzali, Heinz Wiendl, Sven G Meut. Myelin oligodendrocyte glycoprotein (MOG35-55) induced experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice. Journal of visualized experiments : JoVE. issue 86. 2015-06-10. PMID:24797125. |
c57bl/6 mice are the commonly used strain for transgenic mouse construction and respond among others to myelin oligodendrocyte glycoprotein (mog). |
2015-06-10 |
2023-08-13 |
mouse |
| Ali Radjavi, Igor Smirnov, Jonathan Kipni. Brain antigen-reactive CD4+ T cells are sufficient to support learning behavior in mice with limited T cell repertoire. Brain, behavior, and immunity. vol 35. 2015-05-27. PMID:24012647. |
moreover, transfer of a monoclonal t cell population reactive to the central nervous system (cns) antigen, myelin oligodendrocyte glycoprotein (mog), was sufficient to improve cognitive task performance in otherwise impaired otii mice, raising the possibility that the antigen-specificity requirement of pro-cognitive t cells may be directed against cns-derived self-antigens. |
2015-05-27 |
2023-08-12 |
mouse |
| Shukkur M Farooq, Hossam M Ashou. In vitro-induced cell-mediated immune deviation to encephalitogenic antigens. Brain, behavior, and immunity. vol 35. 2015-05-27. PMID:24095895. |
the encephalitogenic antigens myelin oligodendrocyte glycoprotein (mog) and myelin basic protein (mbp) have an obvious clinical relevance. |
2015-05-27 |
2023-08-12 |
mouse |
| O M Dumitrascu, K R Mott, H Ghias. A comparative study of experimental mouse models of central nervous system demyelination. Gene therapy. vol 21. issue 6. 2015-05-12. PMID:24718267. |
mice with hsv-il-2- and myelin oligodendrocyte glycoprotein (mog)-induced demyelinating diseases demonstrated a similar pattern and distribution of demyelination in their brain, spinal cord (sc) and optic nerves (ons). |
2015-05-12 |
2023-08-13 |
mouse |
| Michael W Y Chan, Chia-Bin Chang, Chien-Hsueh Tung, Justin Sun, Jau-Ling Suen, Shu-Fen W. Low-dose 5-aza-2'-deoxycytidine pretreatment inhibits experimental autoimmune encephalomyelitis by induction of regulatory T cells. Molecular medicine (Cambridge, Mass.). vol 20. 2015-05-11. PMID:24869907. |
we found that disease activity was inhibited in a myelin oligodendrocyte glycoprotein (mog) peptide-induced eae mouse briefly pretreated with low-dose (0.15 mg/kg) 5-aza, ameliorating significant cns inflammatory responses, as indicated by greatly decreased proinflammatory cytokines. |
2015-05-11 |
2023-08-13 |
mouse |
| M Baumann, K Sahin, C Lechner, E M Hennes, K Schanda, S Mader, M Karenfort, C Selch, M Häusler, A Eisenkölbl, M Salandin, U Gruber-Sedlmayr, A Blaschek, V Kraus, S Leiz, J Finsterwalder, T Gotwald, G Kuchukhidze, T Berger, M Reindl, K Rostás. Clinical and neuroradiological differences of paediatric acute disseminating encephalomyelitis with and without antibodies to the myelin oligodendrocyte glycoprotein. Journal of neurology, neurosurgery, and psychiatry. vol 86. issue 3. 2015-05-11. PMID:25121570. |
myelin oligodendrocyte glycoprotein (mog) antibodies have been recently described in children with acute disseminating encephalomyelitis (adem), but the clinical and neuroradiological characterisation of this subgroup is lacking. |
2015-05-11 |
2023-08-13 |
Not clear |