| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui Zheng, Han Zhang, Feng Liu, Yuanyuan Qi, Hong Jian. T cell-depleted splenocytes from mice pre-immunized with neuroantigen in incomplete Freund's adjuvant involved in protection from experimental autoimmune encephalomyelitis. Immunology letters. vol 157. issue 1-2. 2014-07-31. PMID:24220208. |
in this work, the effects of cd4(-)-, cd8(-)- splenocytes on protection from eae in c57bl/6 mice which were immunized with myelin oligodendrocyte glycoprotein 35-55 (mog)35-55 in ifa were evaluated. |
2014-07-31 |
2023-08-12 |
mouse |
| Jérome de Seze, Nicolas Collongue. Novel advances in the diagnosis and treatment of neuromyelitis optica: is there a need to redefine the gold standard? Expert review of clinical immunology. vol 9. issue 10. 2014-07-14. PMID:24128159. |
it was also recently found that other immunological targets such as myelin oligodendrocyte glycoprotein (mog) may be associated with seronegative nmo patients. |
2014-07-14 |
2023-08-12 |
Not clear |
| Euan R O Allan, Pankaj Tailor, Dale R Balce, Payman Pirzadeh, Neil T McKenna, Bernard Renaux, Amy L Warren, Frank R Jirik, Robin M Yate. NADPH oxidase modifies patterns of MHC class II-restricted epitopic repertoires through redox control of antigen processing. Journal of immunology (Baltimore, Md. : 1950). vol 192. issue 11. 2014-07-02. PMID:24778444. |
additionally, it was found that nox2 deficiency adversely affected the ability of bone marrow-derived macrophages, but not dendritic cells, to process and present the i-a(b)-immunodominant peptide of the autoantigen myelin oligodendrocyte glycoprotein (mog). |
2014-07-02 |
2023-08-13 |
mouse |
| Kevin Rostasy, Markus Reind. Role of autoantibodies in acquired inflammatory demyelinating diseases of the central nervous system in children. Neuropediatrics. vol 44. issue 6. 2014-07-01. PMID:24166146. |
the recent detection of aquaporin-4 (aqp4) and myelin oligodendrocyte glycoprotein (mog) autoantibodies in acquired inflammatory demyelinating diseases, such as neuromyelitis optica, or acute disseminated encephalomyelitis, and multiple sclerosis, in children strongly indicates that b-cell-dependent mechanisms contribute to the pathogenesis. |
2014-07-01 |
2023-08-12 |
Not clear |
| S Flytzani, P Stridh, A O Guerreiro-Cacais, M Marta, M T Hedreul, M Jagodic, T Olsso. Anti-MOG antibodies are under polygenic regulation with the most significant control coming from the C-type lectin-like gene locus. Genes and immunity. vol 14. issue 7. 2014-06-20. PMID:23784360. |
there is evidence supporting a role of myelin oligodendrocyte glycoprotein (mog) humoral immunity in ms. we aimed to determine the genetic regulation of anti-mog antibodies and their involvement in disease, by using mog-induced experimental autoimmune encephalomyelitis (eae) in rat, an animal model that closely mimics human ms. we show polygenic regulation of anti-mog antibodies in two backcross populations, including a major genetic determinant for antibody expression on chromosome 4, amig3. |
2014-06-20 |
2023-08-12 |
human |
| T Kalantari, M H Karimi, B Ciric, Y Yan, A Rostami, E Kamali-Sarvestan. Tolerogenic dendritic cells produced by lentiviral-mediated CD40- and interleukin-23p19-specific shRNA can ameliorate experimental autoimmune encephalomyelitis by suppressing T helper type 17 cells. Clinical and experimental immunology. vol 176. issue 2. 2014-06-20. PMID:24387596. |
in-vitro studies showed that double-transduced bmdcs (cd40(+) p19lv-dcs) resemble tolerogenic dcs due to profound down-regulation of cd40, lower expression of proinflammatory cytokines (il-6 and il-12), increased il-10 production and stronger stimulation of myelin oligodendrocyte glycoprotein (mog)35-55 -specific t cells for production of il-10 compared with cd40lv-dcs, p19lv-dcs and bmdcs transduced with control lentiviral vector (colv-dcs). |
2014-06-20 |
2023-08-12 |
mouse |
| Anne I Boullerne, Paul E Polak, David Braun, Anthony Sharp, Dale Pelligrino, Douglas L Feinstei. Effects of peptide fraction and counter ion on the development of clinical signs in experimental autoimmune encephalomyelitis. Journal of neurochemistry. vol 129. issue 4. 2014-06-15. PMID:24471474. |
the most commonly used immunogen to induce experimental autoimmune encephalomyelitis is mog35-55 , a 21-residue peptide derived from myelin oligodendrocyte glycoprotein (mog). |
2014-06-15 |
2023-08-12 |
mouse |
| Roberto Meza-Romero, Gil Benedek, Xiaolin Yu, Jeffery L Mooney, Rony Dahan, Nerri Duvshani, Richard Bucala, Halina Offner, Yoram Reiter, Gregory G Burrows, Arthur A Vandenbar. HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 192. issue 9. 2014-06-06. PMID:24683185. |
potency of the drα1 domain could be destroyed by trypsin digestion but enhanced by addition of a peptide extension (myelin oligodendrocyte glycoprotein [mog]-35-55 peptide) that provided secondary structure not present in drα1. |
2014-06-06 |
2023-08-12 |
mouse |
| Masami Tanaka, Keiko Tanak. Anti-MOG antibodies in adult patients with demyelinating disorders of the central nervous system. Journal of neuroimmunology. vol 270. issue 1-2. 2014-06-05. PMID:24703097. |
the myelin oligodendrocyte glycoprotein (mog) is considered as a candidate marker of demyelinating disorders of the central nervous system. |
2014-06-05 |
2023-08-13 |
human |
| Jie-Yu Chung, William Figgett, Kirsten Fairfax, Claude Bernard, James Chan, Ban-Hock Toh, Fabienne Mackay, Frank Alderucci. Gene therapy delivery of myelin oligodendrocyte glycoprotein (MOG) via hematopoietic stem cell transfer induces MOG-specific B cell deletion. Journal of immunology (Baltimore, Md. : 1950). vol 192. issue 6. 2014-05-15. PMID:24532581. |
gene therapy delivery of myelin oligodendrocyte glycoprotein (mog) via hematopoietic stem cell transfer induces mog-specific b cell deletion. |
2014-05-15 |
2023-08-12 |
mouse |
| Jie-Yu Chung, William Figgett, Kirsten Fairfax, Claude Bernard, James Chan, Ban-Hock Toh, Fabienne Mackay, Frank Alderucci. Gene therapy delivery of myelin oligodendrocyte glycoprotein (MOG) via hematopoietic stem cell transfer induces MOG-specific B cell deletion. Journal of immunology (Baltimore, Md. : 1950). vol 192. issue 6. 2014-05-15. PMID:24532581. |
we have previously shown in the mouse model of experimental autoimmune encephalomyelitis that transfer of bone marrow (bm) transduced with retrovirus encoding myelin oligodendrocyte glycoprotein (mog) promotes disease resistance and cd4(+) t cell deletion within the thymus. |
2014-05-15 |
2023-08-12 |
mouse |
| Fang Xie, Jiu-Cong Zhang, Han Fu, Jun Che. Age-related decline of myelin proteins is highly correlated with activation of astrocytes and microglia in the rat CNS. International journal of molecular medicine. vol 32. issue 5. 2014-05-09. PMID:24026164. |
in the present study, immunohistochemical mapping was used to investigate the overall expression of myelin basic protein (mbp) and myelin oligodendrocyte glycoprotein (mog) in the central nervous system (cns) of rats in postnatal months 2, 5, 18 and 26. |
2014-05-09 |
2023-08-12 |
rat |
| Cecile Delarasse, Paul Smith, David Baker, Sandra Amo. Novel pathogenic epitopes of myelin oligodendrocyte glycoprotein induce experimental autoimmune encephalomyelitis in C57BL/6 mice. Immunology. vol 140. issue 4. 2014-04-18. PMID:23876060. |
myelin oligodendrocyte glycoprotein (mog), a minor protein of the central nervous system myelin, is recognized as a potential target in multiple sclerosis and neuromyelitis optica. |
2014-04-18 |
2023-08-12 |
mouse |
| Abhinoy Kishore, Anurag Kanaujia, Soma Nag, A M Rostami, Lawrence C Kenyon, Kenneth S Shindler, Jayasri Das Sarm. Different mechanisms of inflammation induced in virus and autoimmune-mediated models of multiple sclerosis in C57BL6 mice. BioMed research international. vol 2013. 2014-04-15. PMID:24083230. |
immunization with myelin oligodendrocyte glycoprotein (mog) induces experimental autoimmune encephalomyelitis (eae), a mainly cd4(+) t-cell-mediated disease, although cd8(+) t cells may play a significant role in demyelination. |
2014-04-15 |
2023-08-12 |
mouse |
| Douglas Kazutoshi Sato, Dagoberto Callegaro, Marco Aurelio Lana-Peixoto, Patrick J Waters, Frederico M de Haidar Jorge, Toshiyuki Takahashi, Ichiro Nakashima, Samira Luisa Apostolos-Pereira, Natalia Talim, Renata Faria Simm, Angelina Maria Martins Lino, Tatsuro Misu, Maria Isabel Leite, Masashi Aoki, Kazuo Fujihar. Distinction between MOG antibody-positive and AQP4 antibody-positive NMO spectrum disorders. Neurology. vol 82. issue 6. 2014-04-01. PMID:24415568. |
to evaluate clinical features among patients with neuromyelitis optica spectrum disorders (nmosd) who have myelin oligodendrocyte glycoprotein (mog) antibodies, aquaporin-4 (aqp4) antibodies, or seronegativity for both antibodies. |
2014-04-01 |
2023-08-12 |
Not clear |
| Kentaro Yomogida, Yuan K Chou, Cong-Qiu Ch. Superantigens induce IL-17 production from polarized Th1 clones. Cytokine. vol 63. issue 1. 2014-03-31. PMID:23664273. |
however, here we demonstrate that highly polarized myelin oligodendrocyte glycoprotein (mog)- and herpes simples virus-specific th1 clones were still capable of producing il-17 upon superantigen stimulation. |
2014-03-31 |
2023-08-12 |
Not clear |
| Manu Rangachari, Vijay K Kuchro. Using EAE to better understand principles of immune function and autoimmune pathology. Journal of autoimmunity. vol 45. 2014-03-31. PMID:23849779. |
eae is classically induced by the immunization of mice with encephalitogenic antigens derived from cns proteins such as proteolipid protein (plp), myelin basic protein (mbp) and myelin oligodendrocyte glycoprotein (mog). |
2014-03-31 |
2023-08-12 |
mouse |
| Mei-Mei Zheng, Xing-Hu Zhan. Cross-reactivity between human cytomegalovirus peptide 981-1003 and myelin oligodendroglia glycoprotein peptide 35-55 in experimental autoimmune encephalomyelitis in Lewis rats. Biochemical and biophysical research communications. vol 443. issue 3. 2014-03-19. PMID:24388990. |
immunization with myelin oligodendroglia glycoprotein (mog) 35-55 also induced inflammatory infiltrates in spinal cords. |
2014-03-19 |
2023-08-12 |
human |
| K Rostásy, S Mader, E M Hennes, K Schanda, V Gredler, A Guenther, A Blaschek, C Korenke, M Pritsch, D Pohl, O Maier, G Kuchukhidze, M Brunner-Krainz, T Berger, M Reind. Persisting myelin oligodendrocyte glycoprotein antibodies in aquaporin-4 antibody negative pediatric neuromyelitis optica. Multiple sclerosis (Houndmills, Basingstoke, England). vol 19. issue 8. 2014-02-28. PMID:23257621. |
recently we showed that antibodies to myelin oligodendrocyte glycoprotein (mog) can be found in aquaporin-4 (aqp4)-immunoglobulin (igg) seronegative pediatric and adult patients with definite and high-risk neuromyelitis optica (nmo). |
2014-02-28 |
2023-08-12 |
Not clear |
| Paula Pifarré, María Gutierrez-Mecinas, Judith Prado, Lorena Usero, Carme Roura-Mir, Mercedes Giralt, Juan Hidalgo, Agustina Garcí. Phosphodiesterase 5 inhibition at disease onset prevents experimental autoimmune encephalomyelitis progression through immunoregulatory and neuroprotective actions. Experimental neurology. vol 251. 2014-02-19. PMID:24211383. |
using myelin oligodendrocyte glycoprotein peptide 35-55 (mog)-induced experimental autoimmune encephalomyelitis (eae) as a model of ms, we recently showed that daily treatment with the phosphodiesterase 5 (pde5) inhibitor sildenafil at peak disease rapidly ameliorates clinical symptoms and neuropathology (pifarre et al., 2011). |
2014-02-19 |
2023-08-12 |
human |