| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Akbar Karimi, Farhad Ahmadi, Kazem Parivar, Mohammad Nabiuni, Saied Haghighi, Sohrab Imani, Hossein Afrouz. Effect of honey bee venom on lewis rats with experimental allergic encephalomyelitis, a model for multiple sclerosis. Iranian journal of pharmaceutical research : IJPR. vol 11. issue 2. 2013-11-19. PMID:24250492. |
experimental allergic encephalomyelitis (eae) is a widely accepted animal model for ms. eae is created in animals by injecting the tissue of myelin basic protein (mbp), cns, or myelin oligodendrocyte glycoprotein (mog) along with the adjuvant. |
2013-11-19 |
2023-08-12 |
rat |
| Sabine Ring, Michael Maas, Dirk M Nettelbeck, Alexander H Enk, Karsten Mahnk. Targeting of autoantigens to DEC205⁺ dendritic cells in vivo suppresses experimental allergic encephalomyelitis in mice. Journal of immunology (Baltimore, Md. : 1950). vol 191. issue 6. 2013-11-13. PMID:23945139. |
to test this system for tolerance induction in experimental allergic encephalomyelitis (eae), we created single-chain fragment variables (scfv) specific for dec205 and fused the scfv to the self-ag myelin oligodendrocyte glycoprotein (mog; scfv dec:mog). |
2013-11-13 |
2023-08-12 |
mouse |
| Mascha S Recks, Eva R Stormanns, Jonas Bader, Stefan Arnhold, Klaus Addicks, Stefanie Kuerte. Early axonal damage and progressive myelin pathology define the kinetics of CNS histopathology in a mouse model of multiple sclerosis. Clinical immunology (Orlando, Fla.). vol 149. issue 1. 2013-11-12. PMID:23899992. |
the ultrastructural data presented here and obtained from studies of myelin oligodendrocyte glycoprotein (mog):35-55-induced experimental autoimmune encephalomyelitis (eae) in c57bl/6 mice delineate that axonal damage and myelin pathology follow different kinetics in the disease course. |
2013-11-12 |
2023-08-12 |
mouse |
| Qian-Qian Yin, Chuan-Xu Liu, Ying-Li Wu, Shao-Fang Wu, Yan Wang, Xia Zhang, Xiao-Juan Hu, Jian-Xin Pu, Ying Lu, Hu-Chen Zhou, Hong-Lin Wang, Hong Nie, Han-Dong Sun, Guo-Qiang Che. Preventive and therapeutic effects of adenanthin on experimental autoimmune encephalomyelitis by inhibiting NF-κB signaling. Journal of immunology (Baltimore, Md. : 1950). vol 191. issue 5. 2013-11-06. PMID:23964105. |
using myelin oligodendrocyte glycoprotein (mog)35-55-induced experimental autoimmune encephalomyelitis (eae), an animal model for multiple sclerosis, we report in this study that adenanthin exerts efficaciously preventive and therapeutic effects on eae accompanied by significant restriction of infiltration of inflammatory cells and demyelination in cns. |
2013-11-06 |
2023-08-12 |
Not clear |
| Petra D Cravens, Bernd C Kieseier, Rehana Hussain, Emily Herndon, Benjamine Arellano, Li-Hong Ben, Brenda C Timmons, Cyd Castro-Rojas, Hans-Peter Hartung, Bernhard Hemmer, Martin S Weber, Scott S Zamvil, Olaf Stüv. The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis. Journal of neuroinflammation. vol 10. 2013-11-05. PMID:23705890. |
c57bl/6 mice younger than eight weeks were resistant to experimental autoimmune encephalomyelitis (eae) following active immunization with myelin oligodendrocyte glycoprotein (mog) peptide (p) 35-55. |
2013-11-05 |
2023-08-12 |
mouse |
| B de Andrade Pereira, C Fraefel, M Hilbe, M Ackermann, C Dresc. Transcriptional targeting of DCs with lentiviral vectors induces antigen-specific tolerance in a mouse model of multiple sclerosis. Gene therapy. vol 20. issue 5. 2013-11-01. PMID:22951454. |
here, we demonstrate that targeting myelin oligodendrocyte glycoprotein (mog) expression to dcs indeed resulted in complete and stable protection from eae. |
2013-11-01 |
2023-08-12 |
mouse |
| Xiao Hu, Xinyue Qi. Lentivirus-mediated estrogen receptor α overexpression in the central nervous system ameliorates experimental autoimmune encephalomyelitis in mice. International journal of molecular medicine. vol 31. issue 5. 2013-10-29. PMID:23525227. |
after 2 weeks, eae was induced with myelin oligodendrocyte glycoprotein (mog) 35-55 peptide. |
2013-10-29 |
2023-08-12 |
mouse |
| Bo Young Choi, Bong Geom Jang, Jin Hee Kim, Jae-Nam Seo, Guang Wu, Min Sohn, Tae Nyoung Chung, Sang Won Su. Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model. Neurobiology of disease. vol 54. 2013-10-21. PMID:23360710. |
experimental autoimmune encephalomyelitis was induced by immunization with myelin oligodendrocyte glycoprotein (mog(35-55)) in female mice. |
2013-10-21 |
2023-08-12 |
mouse |
| Zivar Salehi, Sara Pishgah Hadiyan, Reza Navid. Ciliary neurotrophic factor role in myelin oligodendrocyte glycoprotein expression in Cuprizone-induced multiple sclerosis mice. Cellular and molecular neurobiology. vol 33. issue 4. 2013-10-17. PMID:23443463. |
myelin oligodendrocyte glycoprotein (mog) is a minor component of the myelin sheath, but is an important autoantigen linked to the pathogenesis of ms. ciliary neurotrophic factor (cntf) has been shown to enhance the generation, maturation, and survival of oligodendrocytes in culture medium. |
2013-10-17 |
2023-08-12 |
mouse |
| Pankaj Bansal, Tarique Khan, Uta Bussmeyer, Dilip K Challa, Rafal Swiercz, Ramraj Velmurugan, Raimund J Ober, E Sally War. The encephalitogenic, human myelin oligodendrocyte glycoprotein-induced antibody repertoire is directed toward multiple epitopes in C57BL/6-immunized mice. Journal of immunology (Baltimore, Md. : 1950). vol 191. issue 3. 2013-09-30. PMID:23817425. |
although abs specific for myelin oligodendrocyte glycoprotein (mog) have been detected in patients with multiple sclerosis (ms), their contribution to pathogenesis remains poorly understood. |
2013-09-30 |
2023-08-12 |
mouse |
| Samantha Jilek, Myriam Schluep, Giuseppe Pantaleo, Renaud A Du Pasquie. MOBP-specific cellular immune responses are weaker than MOG-specific cellular immune responses in patients with multiple sclerosis and healthy subjects. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 34. issue 4. 2013-09-26. PMID:22752855. |
myelin oligodendrocyte glycoprotein (mog) and myelin oligodendrocyte basic protein (mobp) were both shown to be highly encephalitogenic in animal models of ms. |
2013-09-26 |
2023-08-12 |
human |
| Takeshi Kezuk. [Optic neuritis--immunological approach to elucidate pathogenesis and develop innovative therapy]. Nippon Ganka Gakkai zasshi. vol 117. issue 3. 2013-09-17. PMID:23631257. |
especially, the disease becomes severe in individuals who possess anti-aqp4 antibodies that target astrocytes, together with anti-myelin oligodendrocyte glycoprotein (mog) antibodies that target myelin oligodendrocytes. |
2013-09-17 |
2023-08-12 |
Not clear |
| Ilaria Cervellini, Pietro Ghezzi, Manuela Mengozz. Therapeutic efficacy of erythropoietin in experimental autoimmune encephalomyelitis in mice, a model of multiple sclerosis. Methods in molecular biology (Clifton, N.J.). vol 982. 2013-09-04. PMID:23456868. |
moreover, we report in detail the protocol to administer epo to mice with myelin oligodendrocyte glycoprotein (mog)-induced chronic progressive eae, and a representative result. |
2013-09-04 |
2023-08-12 |
mouse |
| Kelly M Flynn, Michael Michaud, Joseph A Madr. CD44 deficiency contributes to enhanced experimental autoimmune encephalomyelitis: a role in immune cells and vascular cells of the blood-brain barrier. The American journal of pathology. vol 182. issue 4. 2013-08-27. PMID:23416161. |
in this study, we examined the effect of global cd44 deficiency on myelin oligodendrocyte glycoprotein peptide (mog)-induced experimental autoimmune encephalomyelitis (eae), a murine model of multiple sclerosis. |
2013-08-27 |
2023-08-12 |
mouse |
| Kai-Chen Wang, Ching-Piao Tsai, Chao-Lin Lee, Shao-Yuan Chen, Gu-Jiun Lin, Mao-Hsiung Yen, Huey-Kang Sytwu, Shyi-Jou Che. α-Lipoic acid enhances endogenous peroxisome-proliferator-activated receptor-γ to ameliorate experimental autoimmune encephalomyelitis in mice. Clinical science (London, England : 1979). vol 125. issue 7. 2013-08-13. PMID:23550596. |
in this study, we found that ala restricts the infiltration of inflammatory cells into the cns (central nervous system) in mog (myelin oligodendrocyte glycoprotein)-eae mice, thus reducing the disease severity. |
2013-08-13 |
2023-08-12 |
mouse |
| Jason A Cascio, Cara L Haymaker, Rohit D Divekar, Sarah Zaghouani, Marie-Therese Khairallah, Xiaoxiao Wan, Linda M Rowland, Mermagya Dhakal, Weirong Chen, Habib Zaghouan. Antigen-specific effector CD4 T lymphocytes school lamina propria dendritic cells to transfer innate tolerance. Journal of immunology (Baltimore, Md. : 1950). vol 190. issue 12. 2013-08-12. PMID:23686493. |
indeed, when ig-myelin oligodendrocyte glycoprotein (mog) carrying the mog(35-55) epitope was orally administered into either t cell-sufficient or -deficient mice, only the t cell-sufficient hosts yielded cd8α(+) and cd8α(-) lp dcs that were able to transfer tolerance to a variety of mhc class ii-restricted effector t cells. |
2013-08-12 |
2023-08-12 |
mouse |
| Guilherme S do Olival, Thiago S Faria, Luiz H S Nali, Augusto C P de Oliveira, Jorge Casseb, Jose E Vidal, Vitor B Cavenaghi, Charles P Tilbery, Lenira Moraes, Maria C S Fink, Laura M Sumita, Hervé Perron, Camila M Roman. Genomic analysis of ERVWE2 locus in patients with multiple sclerosis: absence of genetic association but potential role of human endogenous retrovirus type W elements in molecular mimicry with myelin antigen. Frontiers in microbiology. vol 4. 2013-06-28. PMID:23805135. |
finally, since plaque formation in central nervous system (cns) of ms patients is attributed to immunological mechanisms triggered by autoimmune attack against myelin, we also investigated the level of similarity between envelope protein and myelin oligodendrocyte glycoprotein (mog). |
2013-06-28 |
2023-08-12 |
human |
| Mahdia Benkhoucha, Nicolas Molnarfi, Marie-Laure Santiago-Raber, Martin S Weber, Doron Merkler, Mattias Collin, Patrice H Laliv. IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis. Journal of neuroinflammation. vol 9. 2013-06-17. PMID:22943418. |
we demonstrate here that endos has a protective effect in myelin oligodendrocyte glycoprotein peptide amino acid 35-55 (mog(35-55))-induced eae, a chronic neuroinflammatory demyelinating disorder of the central nervous system (cns) in which humoral immune responses are thought to play only a minor role. |
2013-06-17 |
2023-08-12 |
mouse |
| Subo Yuan, Yuqiang Shi, Shao-Jun Tan. Wnt signaling in the pathogenesis of multiple sclerosis-associated chronic pain. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 7. issue 4. 2013-05-24. PMID:22547300. |
the eae model was created by immunization of adult mice (c57bl/6, 10 weeks) with myelin oligodendrocyte glycoprotein (mog) 35-55. |
2013-05-24 |
2023-08-12 |
mouse |
| H Hosseini, D Y Oh, S T Chan, X T Chen, Z Nasa, H Yagita, F Alderuccio, B-H Toh, J Cha. Non-myeloablative transplantation of bone marrow expressing self-antigen establishes peripheral tolerance and completely prevents autoimmunity in mice. Gene therapy. vol 19. issue 11. 2013-04-19. PMID:22071968. |
myeloablative transplantation of bone marrow (bm) engineered to express myelin oligodendrocyte glycoprotein (mog) establishes central intrathymic tolerance and completely prevents mog-induced experimental autoimmune encephalomyelitis (eae) in mice. |
2013-04-19 |
2023-08-12 |
mouse |