| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xuejun Zhang, Jin-Qing Liu, Yun Shi, Hugh H Reid, Richard L Boyd, Mazin Khattabi, Hani Y El-Omrani, Pan Zheng, Yang Liu, Xue-Feng Ba. CD24 on thymic APCs regulates negative selection of myelin antigen-specific T lymphocytes. European journal of immunology. vol 42. issue 4. 2012-06-18. PMID:22213356. |
the cd24-deficient 2d2 tcr transgenic mice (2d2(+) cd24(-/-) ), whose tcr recognizes myelin oligodendrocyte glycoprotein (mog), fail to generate functional 2d2 t cells. |
2012-06-18 |
2023-08-12 |
mouse |
| Xuefang Ren, Kozaburo Akiyoshi, Marjorie R Grafe, Arthur A Vandenbark, Patricia D Hurn, Paco S Herson, Halina Offne. Myelin specific cells infiltrate MCAO lesions and exacerbate stroke severity. Metabolic brain disease. vol 27. issue 1. 2012-06-05. PMID:21989743. |
disruption of the blood-brain barrier (bbb) during stroke allows cns antigens to leak into the peripheral circulation and enhances access of circulating leukocytes to the brain, including those specific for cns antigens such as myelin oligodendrocyte glycoprotein (mog) that can induce experimental autoimmune encephalomyelitis (eae). |
2012-06-05 |
2023-08-12 |
mouse |
| Sarah E Lutz, Cedric S Raine, Celia F Brosna. Loss of astrocyte connexins 43 and 30 does not significantly alter susceptibility or severity of acute experimental autoimmune encephalomyelitis in mice. Journal of neuroimmunology. vol 245. issue 1-2. 2012-06-05. PMID:22342190. |
eae was induced using myelin oligodendrocyte glycoprotein (mog(35-55)) peptide, and mice were monitored for acute expression of disease. |
2012-06-05 |
2023-08-12 |
mouse |
| Ana C Anderson, Rucha Chandwaskar, David H Lee, Jenna M Sullivan, Adam Solomon, Roselynn Rodriguez-Manzanet, Bernhard Greve, Raymond A Sobel, Vijay K Kuchro. A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells. Journal of immunology (Baltimore, Md. : 1950). vol 188. issue 5. 2012-05-31. PMID:22279107. |
we have generated a tcr transgenic mouse that expresses the α- and β-chains of a myelin oligodendrocyte glycoprotein (mog) 35-55-reactive tcr (1c6) on the nod background. |
2012-05-31 |
2023-08-12 |
mouse |
| Richard A O'Connor, Xujian Li, Seth Blumerman, Stephen M Anderton, Randolph J Noelle, Dyana K Dalto. Adjuvant immunotherapy of experimental autoimmune encephalomyelitis: immature myeloid cells expressing CXCL10 and CXCL16 attract CXCR3+CXCR6+ and myelin-specific T cells to the draining lymph nodes rather than the central nervous system. Journal of immunology (Baltimore, Md. : 1950). vol 188. issue 5. 2012-05-31. PMID:22287719. |
subsequently, cd4(+) t cells coexpressing the cognate chemokine receptors cxcr3 and cxcr6 and myelin oligodendrocyte glycoprotein (mog)-specific cd4(+) t cells accumulated within the chemokine-expressing dlns, rather than within the cns. |
2012-05-31 |
2023-08-12 |
mouse |
| Ding Yuan Oh, Peng Cui, Hamid Hosseini, Jennifer Mosse, Ban-Hock Toh, James Cha. Potently immunosuppressive 5-fluorouracil-resistant mesenchymal stromal cells completely remit an experimental autoimmune disease. Journal of immunology (Baltimore, Md. : 1950). vol 188. issue 5. 2012-05-31. PMID:22291191. |
administration of these 5-fu-resistant cd11b(-)cd45(-) mscs 6 d after myelin oligodendrocyte glycoprotein (mog) immunization completely remitted mog-induced experimental autoimmune encephalomyelitis after initial development of mild disease. |
2012-05-31 |
2023-08-12 |
mouse |
| Jianzheng Zheng, Anushka Dasgupta, Oscar A Bizzozer. Changes in 20S subunit composition are largely responsible for altered proteasomal activities in experimental autoimmune encephalomyelitis. Journal of neurochemistry. vol 121. issue 3. 2012-05-24. PMID:22353035. |
we recently reported that the proteasomal peptidase activities are altered in the cerebellum of mice with myelin oligodendrocyte glycoprotein (mog) peptide-induced experimental autoimmune encephalomyelitis (eae). |
2012-05-24 |
2023-08-12 |
mouse |
| Julieann C Durham-Lee, Venkata Usha L Mokkapati, Kathia M Johnson, Olivera Nesi. Amiloride improves locomotor recovery after spinal cord injury. Journal of neurotrauma. vol 28. issue 7. 2012-05-21. PMID:21534729. |
rats receiving amiloride treatment also exhibited a significant increase in myelin oligodendrocyte glycoprotein (mog) levels 35 days after sci at the site of injury (t10) when compared to vehicle-treated controls, which indicated a partial reverse in the decrease of mog observed with injury. |
2012-05-21 |
2023-08-12 |
rat |
| Francesco Girolamo, Giovanni Ferrara, Maurizio Strippoli, Marco Rizzi, Mariella Errede, Maria Trojano, Roberto Perris, Luisa Roncali, Maria Svelto, Tiziana Mennini, Daniela Virgintin. Cerebral cortex demyelination and oligodendrocyte precursor response to experimental autoimmune encephalomyelitis. Neurobiology of disease. vol 43. issue 3. 2012-05-21. PMID:21679768. |
the analysis demonstrated that a2b5(+) glial restricted progenitors (grps) and ng2(+)/pdgfr-α(+) oligodendrocyte precursor cells (opcs) were increased in number during "early" disease, 20 days post mog immunization, whereas in the "late" disease, 39 days post-immunization, they were strongly diminished, and there was an accompanying reduction in ng2(+)/o4(+) pre-oligodendrocytes and gst-π mature oligodendrocytes. |
2012-05-21 |
2023-08-12 |
mouse |
| Paul E Polak, Sergey Kalinin, David Braun, Anthony Sharp, Shao X Lin, Douglas L Feinstei. The vincamine derivative vindeburnol provides benefit in a mouse model of multiple sclerosis: effects on the Locus coeruleus. Journal of neurochemistry. vol 121. issue 2. 2012-05-21. PMID:22288774. |
female c57bl/6 mice were immunized with myelin oligodendrocyte glycoprotein (mog)(35-55) peptide, and treated with vindeburnol at the first appearance of clinical signs. |
2012-05-21 |
2023-08-12 |
mouse |
| Hongwei Qin, Wen-I Yeh, Patrizia De Sarno, Andrew T Holdbrooks, Yudong Liu, Michelle T Muldowney, Stephanie L Reynolds, Lora L Yanagisawa, Thomas H Fox, Keun Park, Laurie E Harrington, Chander Raman, Etty N Benvenist. Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 13. 2012-05-21. PMID:22411837. |
the myeloid-specific socs3-deficient mice are vulnerable to myelin oligodendrocyte glycoprotein (mog)-induced eae, with a severe, nonresolving atypical form of disease. |
2012-05-21 |
2023-08-12 |
mouse |
| Lakshmi Devi Kandagaddala, Min-Jung Kang, Bong Chul Chung, Tucker A Patterson, Oh-Seung Kwo. Expression and activation of matrix metalloproteinase-9 and NADPH oxidase in tissues and plasma of experimental autoimmune encephalomyelitis in mice. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 64. issue 1-2. 2012-05-14. PMID:20810258. |
experimental autoimmune encephalomyelitis (eae) is a widely used animal model for multiple sclerosis (ms) that can be induced by immunization with myelin antigens such as myelin oligodendrocyte glycoprotein (mog). |
2012-05-14 |
2023-08-12 |
mouse |
| Pedro J Gonzalez-Cabrera, Stuart M Cahalan, Nhan Nguyen, Gor Sarkisyan, Nora B Leaf, Michael D Cameron, Tomoyuki Kago, Hugh Rose. S1P(1) receptor modulation with cyclical recovery from lymphopenia ameliorates mouse model of multiple sclerosis. Molecular pharmacology. vol 81. issue 2. 2012-05-04. PMID:22031473. |
using daily treatment with 10 mg/kg 2-(4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1h-inden-1-yl amino)ethanol (cym-5442) at the onset of clinical signs in myelin oligodendrocyte glycoprotein mog(35-55)- induced experimental allergic encephalomyelitis (eae), we assessed clinical scores, cns cellular infiltration, demyelination, and gliosis for 12 days with cym-5442, vehicle, or fingolimod. |
2012-05-04 |
2023-08-12 |
mouse |
| Eduardo Huarte, Agnieszka Rynda-Apple, Carol Riccardi, Jerod A Skyberg, Sarah Golden, Maryclare F Rollins, Andrew G Ramstead, Larissa O Jackiw, Massimo Maddaloni, David W Pascua. Tolerogen-induced interferon-producing killer dendritic cells (IKDCs) protect against EAE. Journal of autoimmunity. vol 37. issue 4. 2012-04-02. PMID:22018711. |
here, we show ikdcs play an essential role in the resolution of experimental autoimmune encephalomyelitis (eae) upon treatment with the tolerizing agent, myelin oligodendrocyte glycoprotein (mog), genetically fused to reovirus protein σ1 (termed mog-pσ1). |
2012-04-02 |
2023-08-12 |
Not clear |
| Ahmad Othman, David M Frim, Paul Polak, Snezana Vujicic, Barry G W Arnason, Anne I Boullern. Olig1 is expressed in human oligodendrocytes during maturation and regeneration. Glia. vol 59. issue 6. 2012-03-26. PMID:21446039. |
we profiled by quantitative pcr (qpcr) the sequential mrna expression of transcription factors olig1, olig2, nkx2.2, sox10, pparδ, pparγ, cyclic nucleotide phosphodiesterase (cnp), myelin basic protein (mbp), myelin-associated glycoprotein (mag) and myelin oligodendrocyte glycoprotein (mog). |
2012-03-26 |
2023-08-12 |
human |
| Petra D Cravens, Rehana Z Hussain, Tresa E Zacharias, Li-Hong Ben, Emily Herndon, Ramya Vinnakota, Doris Lambracht-Washington, Stefan Nessler, Scott S Zamvil, Todd N Eagar, Olaf Stüv. Lymph node-derived donor encephalitogenic CD4+ T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet. Journal of neuroinflammation. vol 8. 2012-02-23. PMID:21702922. |
donor mice were immunized with myelin oligodendrocyte glycoprotein (mog)p35-55 in complete freund's adjuvant (cfa) followed by pertussis toxin (pt). |
2012-02-23 |
2023-08-12 |
mouse |
| Ghasem Mosayebi, Seyed Mohammad Moazzen. Spleen and liver dendritic cells differ in their tolerogenic and cytokine induction potential. Iranian journal of allergy, asthma, and immunology. vol 10. issue 3. 2012-02-21. PMID:21891822. |
cd11c+ dcs were separated from the liver and spleen of c57bl/6 mice and pulsed with myelin oligodendrocyte glycoprotein (mog) peptide 35-55. |
2012-02-21 |
2023-08-12 |
mouse |
| Roxana del Rio, Rajkumar Noubade, Naresha Saligrama, Emma H Wall, Dimitry N Krementsov, Matthew E Poynter, James F Zachary, Robin L Thurmond, Cory Teusche. Histamine H4 receptor optimizes T regulatory cell frequency and facilitates anti-inflammatory responses within the central nervous system. Journal of immunology (Baltimore, Md. : 1950). vol 188. issue 2. 2012-02-21. PMID:22147765. |
b'in this study, we show that, compared with wild-type mice, animals with a disrupted hrh4 (h(4)rko) develop more severe myelin oligodendrocyte glycoprotein (mog)(35\\x{2013}55)-induced experimental allergic encephalomyelitis.' |
2012-02-21 |
2023-08-12 |
mouse |
| Manjunatha Ankathatti Munegowda, Yulin Deng, Rajni Chibbar, Qingyong Xu, Andrew Freywald, Sean J Mulligan, Sylvia van Drunen Littel-van den Hurk, Deming Sun, Sidong Xiong, Jim Xian. A distinct role of CD4+ Th17- and Th17-stimulated CD8+ CTL in the pathogenesis of type 1 diabetes and experimental autoimmune encephalomyelitis. Journal of clinical immunology. vol 31. issue 5. 2012-02-14. PMID:21674137. |
we generated ovalbumin (ova)- or myelin oligodendrocyte glycoprotein (mog)-specific th17 cells expressing rorγt and il-17 by in vitro co-culturing ova-pulsed and mog(35-55) peptide-pulsed dendritic cells (dc(ova) and dc(mog)) with cd4(+) t cells derived from transgenic otii and mog-t cell receptor mice, respectively. |
2012-02-14 |
2023-08-12 |
mouse |
| Suzan Dziennis, Sarah Mader, Kozaburo Akiyoshi, Xuefang Ren, Patricia Ayala, Gregory G Burrows, Arthur A Vandenbark, Paco S Herson, Patricia D Hurn, Halina A Offne. Therapy with recombinant T-cell receptor ligand reduces infarct size and infiltrating inflammatory cells in brain after middle cerebral artery occlusion in mice. Metabolic brain disease. vol 26. issue 2. 2012-02-10. PMID:21472429. |
recombinant t-cell receptor (tcr) ligand (rtl)551 is designed as a partial tcr agonist for myelin oligodendrocyte glycoprotein (mog)-reactive t cells and has demonstrated the capacity to limit infarct volume and inflammation in brain when administered to mice undergoing middle cerebral artery occlusion (mcao). |
2012-02-10 |
2023-08-12 |
mouse |